The genomes of a monogenic fly: views of primitive sex chromosomes.

Abstract:

:The production of male and female offspring is often determined by the presence of specific sex chromosomes which control sex-specific expression, and sex chromosomes evolve through reduced recombination and specialized gene content. Here we present the genomes of Chrysomya rufifacies, a monogenic blow fly (females produce female or male offspring, exclusively) by separately sequencing and assembling each type of female and the male. The genomes (> 25X coverage) do not appear to have any sex-linked Muller F elements (typical for many Diptera) and exhibit little differentiation between groups supporting the morphological assessments of C. rufifacies homomorphic chromosomes. Males in this species are associated with a unimodal coverage distribution while females exhibit bimodal coverage distributions, suggesting a potential difference in genomic architecture. The presence of the individual-sex draft genomes herein provides new clues regarding the origination and evolution of the diverse sex-determining mechanisms observed within Diptera. Additional genomic analysis of sex chromosomes and sex-determining genes of other blow flies will allow a refined evolutionary understanding of how flies with a typical X/Y heterogametic amphogeny (male and female offspring in similar ratios) sex determination systems evolved into one with a dominant factor that results in single sex progeny in a chromosomally monomorphic system.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Andere AA,Pimsler ML,Tarone AM,Picard CJ

doi

10.1038/s41598-020-72880-0

subject

Has Abstract

pub_date

2020-09-25 00:00:00

pages

15728

issue

1

issn

2045-2322

pii

10.1038/s41598-020-72880-0

journal_volume

10

pub_type

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