The chemically driven phase transformation in a memristive abacus capable of calculating decimal fractions.

Abstract:

:The accurate calculation of decimal fractions is still a challenge for the binary-coded computations that rely on von Neumann paradigm. Here, we report a kind of memristive abacus based on synaptic Ag-Ge-Se device, in which the memristive long-term potentiation and depression are caused by a chemically driven phase transformation. The growth and the rupture of conductive Ag₂Se dendrites are confirmed via in situ transmission electron microscopy. By detecting the change in memristive synaptic weight, the quantity of input signals applied onto the device can be "counted". This makes it possible to achieve the functions of abacus that is basically a counting frame. We demonstrate through experimental studies that this kind of memristive abacus can calculate decimal fractions in the light of the abacus algorithms. This approach opens up a new route to do decimal arithmetic in memristive devices without encoding binary-coded decimal.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Xu H,Xia Y,Yin K,Lu J,Yin Q,Yin J,Sun L,Liu Z

doi

10.1038/srep01230

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

1230

issn

2045-2322

journal_volume

3

pub_type

杂志文章
  • Arc/Arg3.1 has an activity-regulated interaction with PICK1 that results in altered spatial dynamics.

    abstract::Activity-regulated cytoskeleton-associated protein (Arc; also known as Arg3.1) is an immediate early gene product that is transcribed in dendritic spines and, to date, has been best characterized as a positive regulator of AMPAR endocytosis during long-term depression (LTD) through interaction with endocytic proteins....

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-32821-4

    authors: Goo BMSS,Sanstrum BJ,Holden DZY,Yu Y,James NG

    更新日期:2018-10-02 00:00:00

  • Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry.

    abstract::Immunoaffinity enrichment of proteotypic peptides, coupled with selected reaction monitoring, enables indirect protein quantification. However the lack of suitable antibodies limits its widespread application. We developed a method in which multi-specific antibodies are used to enrich groups of peptides, thus facilita...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08759

    authors: Weiß F,Schnabel A,Planatscher H,van den Berg BH,Serschnitzki B,Nuessler AK,Thasler WE,Weiss TS,Reuss M,Stoll D,Templin MF,Joos TO,Marcus K,Poetz O

    更新日期:2015-03-04 00:00:00

  • Vertical migration by bulk phytoplankton sustains biodiversity and nutrient input to the surface ocean.

    abstract::Phytoplankton subsumes the great variety of unicellular photoautotrophs that perform roughly half of Earth's primary production. They achieve this despite their challenging oceanic habitat, with opposing vertical gradients of nutrients (which often limit their growth near the surface) and light (which becomes limiting...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-57890-2

    authors: Wirtz K,Smith SL

    更新日期:2020-01-24 00:00:00

  • Smooth and flat phase-locked Kerr frequency comb generation by higher order mode suppression.

    abstract::High-Q microresonator is perceived as a promising platform for optical frequency comb generation, via dissipative soliton formation. In order to achieve a higher quality factor and obtain the necessary anomalous dispersion, multi-mode waveguides were previously implemented in Si3N4 microresonators. However, coupling b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep26255

    authors: Huang SW,Liu H,Yang J,Yu M,Kwong DL,Wong CW

    更新日期:2016-05-16 00:00:00

  • Localized Down-regulation of P-glycoprotein by Focused Ultrasound and Microbubbles induced Blood-Brain Barrier Disruption in Rat Brain.

    abstract::Multi-drug resistant efflux transporters found in Blood-Brain Barrier (BBB) acts as a functional barrier, by pumping out most of the drugs into the blood. Previous studies showed focused ultrasound (FUS) induced microbubble oscillation can disrupt the BBB by loosening the tight junctions in the brain endothelial cells...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep31201

    authors: Cho H,Lee HY,Han M,Choi JR,Ahn S,Lee T,Chang Y,Park J

    更新日期:2016-08-11 00:00:00

  • Molecular and Histopathological Study on the Ameliorative Impacts of Petroselinum Crispum and Apium Graveolens against Experimental Hyperuricemia.

    abstract::Hyperuricemia is an abnormal metabolic condition characterized by an increase in uric acid levels in the blood. It is the cause of gout, manifested by inflammatory arthritis, pain and disability. This study examined the possible ameliorative impacts of parsley (PAR) and celery (CEL) as hypouricemic agents at biochemic...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-66205-4

    authors: Soliman MM,Nassan MA,Aldhahrani A,Althobaiti F,Mohamed WA

    更新日期:2020-06-11 00:00:00

  • Genome-wide characterization and expression analysis suggested diverse functions of the mechanosensitive channel of small conductance-like (MSL) genes in cereal crops.

    abstract::Mechanosensitive ion channels are pore-forming transmembrane proteins that allow ions to move down their electrochemical gradient in response to mechanical stimuli. They participate in many plant developmental processes including the maintenance of plastid shape, pollen tube growth, etc. Herein, a total of 11, 10, 6, ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73627-7

    authors: Kaur A,Taneja M,Tyagi S,Sharma A,Singh K,Upadhyay SK

    更新日期:2020-10-06 00:00:00

  • Control strategies of 3-cell Central Pattern Generator via global stimuli.

    abstract::The study of the synchronization patterns of small neuron networks that control several biological processes has become an interesting growing discipline. Some of these synchronization patterns of individual neurons are related to some undesirable neurological diseases, and they are believed to play a crucial role in ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep23622

    authors: Lozano Á,Rodríguez M,Barrio R

    更新日期:2016-03-29 00:00:00

  • Chloroquine inhibits human CD4+ T-cell activation by AP-1 signaling modulation.

    abstract::Chloroquine (CQ) is widely used as an anti-inflammatory therapeutic for rheumatic diseases. Although its modes of action on the innate immune system are well described, there is still insufficient knowledge about its direct effects on the adaptive immune system. Thus, we evaluated the influence of CQ on activation par...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42191

    authors: Schmidt RL,Jutz S,Goldhahn K,Witzeneder N,Gerner MC,Trapin D,Greiner G,Hoermann G,Steiner G,Pickl WF,Burgmann H,Steinberger P,Ratzinger F,Schmetterer KG

    更新日期:2017-02-07 00:00:00

  • The Clinical Characteristics and Outcomes of Follicular Bronchiolitis in Chinese Adult Patients.

    abstract::Follicular bronchiolitis (FB) is a rare interstitial lung disease (ILD) and has been reported in diverse clinical contexts. Six FB patients demonstrated by surgical lung biopsy (SLB) were reviewed between 2009 and 2017 from Nanjing Drum Tower Hospital in China. The average age of subjects was 42 years old (range: 31-5...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-25670-8

    authors: Lu J,Ma M,Zhao Q,Meng F,Wang D,Cai H,Cao M

    更新日期:2018-05-08 00:00:00

  • Photothermal therapy improves the efficacy of a MEK inhibitor in neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.

    abstract::Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors with low survival rates and the leading cause of death in neurofibromatosis type 1 (NF1) patients under 40 years old. Surgical resection is the standard of care for MPNSTs, but is often incomplete and can generate loss of function, necessitating t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep37035

    authors: Sweeney EE,Burga RA,Li C,Zhu Y,Fernandes R

    更新日期:2016-11-11 00:00:00

  • Development of an electronic navigation system for elimination of examiner-dependent factors in the ultrasound screening for developmental dysplasia of the hip in newborns.

    abstract::To develop an electronic navigation system to increase reliability and comparability in the ultrasound screening of developmental dysplasia of the hip (DDH). The impact of the navigation system on transducer positioning and on sonographic measurements according to Graf was analyzed. Twenty hips in newborns were examin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73536-9

    authors: Kolb A,Chiari C,Schreiner M,Heisinger S,Willegger M,Rettl G,Windhager R

    更新日期:2020-10-02 00:00:00

  • Mild synthesis of isoxazoline derivatives via an efficient [4 + 1] annulation reaction of transient nitrosoalkenes and sulfur ylides.

    abstract::An efficient [4 + 1] annulation between α-bromooximes and sulfur ylides via in situ generation of nitrosoalkenes under mild basic reaction conditions has been developed, providing an expeditious and scalable approach to synthesize biologically interesting isoxazoline derivatives with good to excellent yields. ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-021-81370-w

    authors: Hua TB,Liu CX,Hu WM,Wang L,Yang QQ

    更新日期:2021-01-22 00:00:00

  • Alpha B-crystallin C-802G polymorphism and colorectal cancer susceptibility and clinical outcome in Chinese population.

    abstract::Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and Alpha B-crystallin (CRYAB) protein has been identified as a prognostic biomarker for CRC. We evaluated CRYAB C-802G (rs14133)polymorphism in association with CRC risk and survival in Chinese population. We genotyped for CRYAB C-802G (rs14133), ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29589-y

    authors: Wu X,Zheng YZ,Han B,Wang K

    更新日期:2018-08-06 00:00:00

  • Following a potential epileptogenic insult, prolonged high rates of nonlinear dynamical regimes of intermittency type is the hallmark of epileptogenesis.

    abstract::The lack of a marker of epileptogenesis is an unmet medical need, not only from the clinical perspective but also from the point of view of the pre-clinical research. Indeed, the lack of this kind of marker affects the investigations on the mechanisms of epileptogenesis as well as the development of novel therapeutic ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep31129

    authors: Rizzi M,Weissberg I,Milikovsky DZ,Friedman A

    更新日期:2016-08-04 00:00:00

  • Dilute-As AlNAs Alloy for Deep-Ultraviolet Emitter.

    abstract::The band structures of dilute-As AlNAs alloys with As composition ranging from 0% up to 12.5% are studied by using First-Principle Density Functional Theory (DFT) calculation. The energy band gap shows remarkable reduction from 6.19 eV to 3.87 eV with small amount of As content in the AlNAs alloy, which covers the dee...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22215

    authors: Tan CK,Borovac D,Sun W,Tansu N

    更新日期:2016-02-24 00:00:00

  • Microperimetry and multimodal imaging in polypoidal choroidal vasculopathy.

    abstract::Polypoidal choroidal vasculopathy (PCV) is a degenerative macular disease. The study determined the topographical concordance in the areal extent of PCV, defined by indocyanine green angiography (ICGA), and the corresponding outcomes from spectral-domain optical coherence tomography (SD-OCT) and microperimetry, in 25 ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-33781-5

    authors: Acton JH,Ogino K,Akagi Y,Wild JM,Yoshimura N

    更新日期:2018-10-25 00:00:00

  • A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters.

    abstract::In humans, the H+-coupled Fe2+ transporter DMT1 (SLC11A2) is essential for proper maintenance of iron homeostasis. While X-ray diffraction has recently unveiled the structure of the bacterial homologue ScaDMT as a LeuT-fold transporter, the exact mechanism of H+-cotransport has remained elusive. Here, we used a combin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-06446-y

    authors: Pujol-Giménez J,Hediger MA,Gyimesi G

    更新日期:2017-07-28 00:00:00

  • Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium.

    abstract::FcRn mediates recycling and transcytosis of IgG and albumin in various cell types. The MHC-class-I-like protein of the FcRn heterodimer is encoded by FCGRT. Few determinants of variable FCGRT expression in humans have been identified so far. In this study, we investigated the presence of DNA methylation in regulatory ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-45203-1

    authors: Cejas RB,Ferguson DC,Quiñones-Lombraña A,Bard JE,Blanco JG

    更新日期:2019-06-17 00:00:00

  • Tissue remodeling after ocular surface reconstruction with denuded amniotic membrane.

    abstract::Amniotic membrane (AM) has been widely used as a temporary or permanent graft in the treatment of various ocular surface diseases. In this study, we compared the epithelial wound healing and tissue remodeling after ocular surface reconstruction with intact amniotic membrane (iAM) or denuded amniotic membrane (dAM). Pa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24694-4

    authors: Jie J,Yang J,He H,Zheng J,Wang W,Zhang L,Li Z,Chen J,Vimalin Jeyalatha M,Dong N,Wu H,Liu Z,Li W

    更新日期:2018-04-23 00:00:00

  • Cross-talk between Human Papillomavirus Oncoproteins and Hedgehog Signaling Synergistically Promotes Stemness in Cervical Cancer Cells.

    abstract::Viral oncoproteins E6/E7 play key oncogenic role in human papillomavirus (HPV)-mediated cervical carcinogenesis in conjunction with aberrant activation of cellular signaling events. GLI-signaling has been implicated in metastasis and tumor recurrence of cervical cancer. However, the interaction of GLI-signaling with H...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep34377

    authors: Vishnoi K,Mahata S,Tyagi A,Pandey A,Verma G,Jadli M,Singh T,Singh SM,Bharti AC

    更新日期:2016-09-28 00:00:00

  • RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143.

    abstract::Nitric oxide (NO)-induced apoptosis in neurons is an important cause of neurodegenerative disease in humans. The cold-inducible protein RBM3 mediates the protective effects of cooling on apoptosis induced by various insults. However, whether RBM3 protects neural cells from NO-induced apoptosis is unclear. This study a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41738

    authors: Yang HJ,Ju F,Guo XX,Ma SP,Wang L,Cheng BF,Zhuang RJ,Zhang BB,Shi X,Feng ZW,Wang M

    更新日期:2017-01-30 00:00:00

  • The archaeological ensemble from Campoverde (Agro Pontino, central Italy): new constraints on the Last Interglacial sea level markers.

    abstract::We present a combined geomorphological and biochronological study aimed at providing age constraints to the deposits forming a wide paleo-surface in the coastal area of the Tyrrhenian Sea, south of Anzio promontory (central Italy). We review the faunal assemblage recovered in Campoverde, evidencing the occurrence of t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36111-x

    authors: Marra F,Petronio C,Ceruleo P,Di Stefano G,Florindo F,Gatta M,La Rosa M,Rolfo MF,Salari L

    更新日期:2018-12-13 00:00:00

  • Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice.

    abstract::To understand the role of commensal gut bacteria on the progression of cognitive decline in Alzheimer's disease via the microbiota-gut-brain axis, we isolated anti-inflammatory Bifidobacterium longum (NK46) from human gut microbiota, which potently inhibited gut microbiota endotoxin production and suppressed NF-κB act...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-48342-7

    authors: Lee HJ,Lee KE,Kim JK,Kim DH

    更新日期:2019-08-14 00:00:00

  • Sonic Hedgehog is expressed by hilar mossy cells and regulates cellular survival and neurogenesis in the adult hippocampus.

    abstract::Sonic hedgehog (Shh) is a multifunctional signaling protein governing pattern formation, proliferation and cell survival during embryogenesis. In the adult brain, Shh has neurotrophic function and is implicated in hippocampal neurogenesis but the cellular source of Shh in the hippocampus remains ill defined. Here, we ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53192-4

    authors: Gonzalez-Reyes LE,Chiang CC,Zhang M,Johnson J,Arrillaga-Tamez M,Couturier NH,Reddy N,Starikov L,Capadona JR,Kottmann AH,Durand DM

    更新日期:2019-11-22 00:00:00

  • Risk factors of treatment failure and 30-day mortality in patients with bacteremia due to MRSA with reduced vancomycin susceptibility.

    abstract::Bacteremia caused by MRSA with reduced vancomycin susceptibility (MRSA-RVS) frequently resulted in treatment failure and mortality. The relation of bacterial factors and unfavorable outcomes remains controversial. We retrospectively reviewed clinical data of patients with bacteremia caused by MRSA with vancomycin MIC ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-26277-9

    authors: Yang CC,Sy CL,Huang YC,Shie SS,Shu JC,Hsieh PH,Hsiao CH,Chen CJ

    更新日期:2018-05-18 00:00:00

  • Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations.

    abstract::Mathematical models of metabolism from bacterial systems biology have proven their utility across multiple fields, for example metabolic engineering, growth phenotype simulation, and biological discovery. The usefulness of the models stems from their ability to compute a link between genotype and phenotype, but their ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep16025

    authors: Aziz RK,Monk JM,Lewis RM,In Loh S,Mishra A,Abhay Nagle A,Satyanarayana C,Dhakshinamoorthy S,Luche M,Kitchen DB,Andrews KA,Fong NL,Li HJ,Palsson BO,Charusanti P

    更新日期:2015-11-04 00:00:00

  • Post-treatment levels of plasma 25- and 1,25-dihydroxy vitamin D and mortality in men with aggressive prostate cancer.

    abstract::Vitamin D may reduce mortality from prostate cancer (PC). We examined the associations of post-treatment plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations with PC mortality. Participants were PC cases from the New South Wales Prostate Cancer Care. All contactable and consenting participants, at 4.9...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62182-w

    authors: Nair-Shalliker V,Bang A,Egger S,Clements M,Gardiner RA,Kricker A,Seibel MJ,Chambers SK,Kimlin MG,Armstrong BK,Smith DP

    更新日期:2020-05-08 00:00:00

  • Response of Human Osteoblast to n-HA/PEEK--Quantitative Proteomic Study of Bio-effects of Nano-Hydroxyapatite Composite.

    abstract::Nano-sized hydroxyapatite (n-HA) is considered as a bio-active material, which is often mixed into bone implant material, polyetheretherketone (PEEK). To reveal the global protein expression modulations of osteoblast in response to direct contact with the PEEK composite containing high level (40%) nano-sized hydroxyap...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep22832

    authors: Zhao M,Li H,Liu X,Wei J,Ji J,Yang S,Hu Z,Wei S

    更新日期:2016-03-09 00:00:00

  • Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function.

    abstract::RNA-binding proteins are key regulators of post-transcriptional processes such as alternative splicing and mRNA stabilization. Rbm24 acts as a regulator of alternative splicing in heart and skeletal muscle, and is essential for sarcomere assembly. Homozygous inactivation of Rbm24 in mice disrupts cardiac development a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-64667-0

    authors: de Groot NE,van den Hoogenhof MMG,Najafi A,van der Made I,van der Velden J,Beqqali A,Pinto YM,Creemers EE

    更新日期:2020-05-06 00:00:00