Abstract：
:Follicular bronchiolitis (FB) is a rare interstitial lung disease (ILD) and has been reported in diverse clinical contexts. Six FB patients demonstrated by surgical lung biopsy (SLB) were reviewed between 2009 and 2017 from Nanjing Drum Tower Hospital in China. The average age of subjects was 42 years old (range: 31-55 years). The clinical symptoms were very mild. The laboratory findings showed elevated Erythrocyte sedimentation rate (ESR) and serum globulin and anemia. Pulmonary function tests were normal in four cases. Five cases had underlying diseases, such as, Sjo¨gren's syndrome, multi-centric castlemans' disease, idiopathic pneumonia with autoimmune features and abscess. Five cases presented as interstitial lung disease (ILD) on chest imaging with centrilobular or peribronchiolar nodules, ground glass opacities, interlobular septal thickening, cysts and bronchiectasis. Isolated mass was in one patient. The histopathology suggested the changes of FB in all subjects. Prednisone and/or cyclophosphamide were used in four cases, one did the surgery and the other was clinically monitored. All cases were alive at the end of follow up. The adult patients of FB usually have mild symptoms, ILD and underlying diseases. The definite diagnosis needs SLB. The prognosis is depended on their underlying conditions.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lu J,Ma M,Zhao Q,Meng F,Wang D,Cai H,Cao Mdoi
10.1038/s41598-018-25670-8subject
Has Abstractpub_date
2018-05-08 00:00:00pages
7300issue
1issn
2045-2322pii
10.1038/s41598-018-25670-8journal_volume
8pub_type
杂志文章abstract：:MADS-box transcription factors widely regulate all aspects of plant growth including development and reproduction. Although the MADS-box gene family genes have been extensively characterized in many plants, they have not been studied in closely related species. In this study, 73 and 74 MADS-box genes were identified i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37897-6
更新日期：2019-02-04 00:00:00
abstract：:Metal nitrides have been proposed to replace noble metals in plasmonics for some specific applications. In particular, while titanium nitride (TiN) and zirconium nitride (ZrN) possess localized plasmon resonances very similar to gold in magnitude and wavelength, they benefit from a much higher sustainability to temper...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38647
更新日期：2016-12-09 00:00:00
abstract：:Fear of predation can induce profound changes in the behaviour and physiology of prey species even if predator encounters are infrequent. For echolocating toothed whales, the use of sound to forage exposes them to detection by eavesdropping predators, but while some species exploit social defences or produce cryptic a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55911-3
更新日期：2020-02-06 00:00:00
abstract：:At the moment it is unknown to what extent the impaired function of T lymphocytes in ESRD patients depends on uremia, and to what extent on hemodialysis (HD) procedure. Therefore, the purpose of the study was to evaluate percentages of T lymphocyte subpopulations ex vivo, plasma concentrations of IL12p70, TNF, IL-10, ...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-019-41619-x
更新日期：2019-03-25 00:00:00
abstract：:2D transition metal dichalcogenides (TMDs) have attracted a lot of attention recently for energy-efficient tunneling-field-effect transistor (TFET) applications due to their excellent gate control resulting from their atomically thin dimensions. However, most TMDs have bandgaps (Eg) and effective masses (m(*)) outside...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28515
更新日期：2016-06-27 00:00:00
abstract：:In the phytopathogenic basidiomycete Ustilago maydis, the Num1 protein has a pivotal function in hyphal morphogenesis. Num1 functions as a core component of the spliceosome-associated Prp19/CDC5 complex (NTC). The interaction of Num1 with the kinesin motor Kin1 suggests a connection between a component of the splicing...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-21628-y
更新日期：2018-02-26 00:00:00
abstract：:A variety of pathogenic bacteria infect host eukaryotic cells using protein toxins, which enter the cytosol and exert their cytotoxic effects. Anthrax lethal toxin, for example, utilizes the membrane-spanning translocase, protective antigen (PA) pore, to deliver the protein toxin lethal factor (LF) from the endosome i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11944
更新日期：2015-07-16 00:00:00
abstract：:ABO blood group is associated with cardiovascular disease, with significantly lower risk in blood group O individuals. ABO(H) blood group determinants are expressed on different glycoproteins on platelet surfaces. In addition, ABO(H) structures are also present on VWF glycans. These ABO(H) carbohydrates influence both...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75462-2
更新日期：2020-10-27 00:00:00
abstract：:Analysing the link between terrestrial ecosystem productivity (i.e., Net Primary Productivity: NPP) and extreme climate conditions is vital in the context of increasing threats due to climate change. To reveal the impact of changing extreme conditions on NPP, a copula-based probabilistic model was developed, and the s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55067-0
更新日期：2019-12-12 00:00:00
abstract：:Understanding the response of the plant community to increasing nitrogen (N) deposition is helpful for improving pasture management in semi-arid areas. We implemented a 5-year N addition experiment in a Stipa krylovii steppe of Inner Mongolia, northern China. The aboveground biomass (AGB) and species richness were mea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31919
更新日期：2016-08-30 00:00:00
abstract：:Morphometric correlation networks of cortical thickness, surface area, and gray matter volume have statistically different structural topology. However, there is no report directly describing their correlation patterns in view of interregional covariance. Here, we examined the characteristics of the correlation patter...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26682
更新日期：2016-05-26 00:00:00
abstract：:Technological advances have made it possible to examine dental resin composites using 3D nanometer resolution. This investigation aims to characterize existing dental nano-hybrid and micro-hybrid resin composites through comparing and contrasting nano-computed tomography (nano-CT) with micro-CT and high-resolution SEM...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72599-y
更新日期：2020-09-23 00:00:00
abstract：:Skin allergy is a chronic condition that affects about 20% of the population of the western world. This disease is caused by small reactive compounds, haptens, able to penetrate into the epidermis and modify endogenous proteins, thereby triggering an immunogenic reaction. Phenyl isothiocyanate (PITC) and ethyl isothio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21203
更新日期：2016-02-17 00:00:00
abstract：:Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment. In cases of protracted dia...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62744-y
更新日期：2020-04-02 00:00:00
abstract：:Tractography atlas-based analysis (TABS) is a new diffusion tensor image (DTI) statistical analysis method for detecting and understanding voxel-wise white matter properties along a fiber tract. An important requisite for accurate and sensitive TABS is the availability of a deformation field that is able to register D...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12965-5
更新日期：2017-10-04 00:00:00
abstract：:Tumor-associated macrophages (TAMs) play critical roles in promoting tumor progression and invasion. However, the molecular mechanisms underlying TAM regulation remain to be further investigated and may make significant contributions to cancer treatment. Mammalian microRNAs (miRNAs) have recently been identified as im...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18648
更新日期：2015-12-22 00:00:00
abstract：:Herein, we propose an advanced energy-storage system: all-graphene-battery. It operates based on fast surface-reactions in both electrodes, thus delivering a remarkably high power density of 6,450 W kg(-1)(total electrode) while also retaining a high energy density of 225 Wh kg(-1)(total electrode), which is comparabl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05278
更新日期：2014-06-13 00:00:00
abstract：:Concerns related to pulmonary toxicity and non-specificity of nanoparticles have limited their clinical applications for aerosol delivery of chemotherapeutics in lung cancer. We hypothesized that pulmonary surfactant mimetic nanoparticles that offer pH responsive release specifically in tumor may be a possible solutio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep07085
更新日期：2014-11-18 00:00:00
abstract：:Long non-coding RNAs (lncRNAs) have been found to play important roles in various biological processes; however, many of their functions remain unclear. In this study, we present a novel approach to identify the lncRNA-associated protein-protein interaction (PPI) modules and ascertain their functions in human lung squ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35939
更新日期：2016-10-27 00:00:00
abstract：:Studies investigating association of depression with overall survival (OS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) yielded conflicting results. A nationwide cohort study, which included all adult patients [n = 7,170; depression group, 13.3% (N = 956); non-depression group, 86.7% (N = 6,214...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71208-2
更新日期：2020-09-17 00:00:00
abstract：:Transistor biosensors are mass-fabrication-compatible devices of interest for point of care diagnosis as well as molecular interaction studies. While the actual transistor gates in processors reach the sub-10 nm range for optimum integration and power consumption, studies on design rules for the signal-to-noise ratio ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69493-y
更新日期：2020-07-29 00:00:00
abstract：:Network analysis is an important tool to analyze the structure of complex systems such as tropical forests. Here, we infer spatial proximity networks in tropical forests by using network science. First, we focus on tree neighborhoods to derive spatial tree networks from forest inventory data. In a second step, we cons...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-70052-8
更新日期：2020-08-06 00:00:00
abstract：:Stevia is a natural source of commercially important steviol glycosides (SGs), which share biosynthesis route with gibberellic acids (GAs) through plastidal MEP and cytosolic MVA pathways. Ontogeny-dependent deviation in SGs biosynthesis is one of the key factor for global cultivation of Stevia, has not been studied a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12025-y
更新日期：2017-09-19 00:00:00
abstract：:Solar-driven photoelectrochemical water splitting (PEC-WS) using semiconductor photoelectrodes is considered a promising solution for sustainable, renewable, clean, safe and alternative energy sources such as hydrogen. Here, we report the synthesis and characterization of a novel heterostructure MoS2/GaN to be used as...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56807-y
更新日期：2019-12-27 00:00:00
abstract：:In this study, we analyze the role of different structural variants of proteins in the speciation processes. We separate human and mouse proteomes (taken as a reference) into three previously defined variants of disorder: ordered proteins (ORDPs), structured proteins with intrinsically disordered protein regions (IDPR...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61466-5
更新日期：2020-03-11 00:00:00
abstract：:Two types of periodic and transient motions of large woodpeckers are considered. A drumming woodpecker may be modeled as a harmonic oscillator with a periodic forcing function. The transient behavior that occurs after the forcing is turned off suggests that the double knocks of Campephilus woodpeckers may be modeled i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13035-6
更新日期：2017-10-02 00:00:00
abstract：:Airports can affect birds by hindering acoustic communication. Here, we investigated the impacts of aircraft events on vocal behavior in wood thrush (Hylocichla mustelina) breeding one mile from an airport in Ithaca, NY, USA. We identified the number of wood thrush songs between 0500 and 0800 h at various distances fr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80380-4
更新日期：2021-01-13 00:00:00
abstract：:Color vision requires the activity of cone photoreceptors to be compared in post-receptoral circuitry. Decades of psychophysical measurements have quantified the nature of these comparative interactions on a coarse scale. How such findings generalize to a cellular scale remains unclear. To answer that question, we qua...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26754-1
更新日期：2018-06-04 00:00:00
abstract：:Coleoptera (beetles) is a massively successful order of insects, distinguished by their evolutionarily modified forewings called elytra. These structures are often presumed to have been a major driving force for the successful radiation of this taxon, by providing beetles with protection against a variety of harsh env...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34813
更新日期：2016-10-06 00:00:00
abstract：:Mathematical modelling has been widely used to predict the effects of perturbations to brain networks. An important example is epilepsy surgery, where the perturbation in question is the removal of brain tissue in order to render the patient free of seizures. Different dynamical models have been proposed to represent ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43871-7
更新日期：2019-05-14 00:00:00
