Abstract:
:Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment. In cases of protracted diarrhoea in healthy children or immunocompromised patients, antibiotic treatment is recommended, and the drug of choice is still macrolides, with very low resistance rates in Campylobacter species. However, it is crucial to isolate the causative organism, because some cases, such as Shigella encephalitis, call for initiation of empiric antibiotic treatment. In this study, we compared the incidence, epidemiology, clinical findings and laboratory results of gastroenteritis with dysentery caused by these organisms in children in our area. C. jejuni was found to be the leading pathogen in children hospitalized with bacterial gastroenteritis, followed by Shigella and Salmonella. Macrolides were the drug of choice for Campylobacter, and ceftriaxone and ciprofloxacin were the best empiric treatments for Shigella and Salmonella, respectively.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Sakran W,Hexner-Erlichman Z,Spiegel R,Batheesh H,Halevy R,Koren Adoi
10.1038/s41598-020-62744-ysubject
Has Abstractpub_date
2020-04-02 00:00:00pages
5823issue
1issn
2045-2322pii
10.1038/s41598-020-62744-yjournal_volume
10pub_type
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