Abstract：
:Memory performance results from plasticity, the ability to change with experience. We show that benefit from practice over a few trials, learning slope, is predictive of long-term recall and hippocampal volume across a broad age range and a long period of time, relates to memory training benefit, and is heritable. First, in a healthy lifespan sample (n = 1825, age 4-93 years), comprising 3483 occasions of combined magnetic resonance imaging (MRI) scans and memory tests over a period of up to 11 years, learning slope across 5 trials was uniquely related to performance on a delayed free recall test, as well as hippocampal volume, independent from first trial memory or total memory performance across the five learning trials. Second, learning slope was predictive of benefit from memory training across ten weeks in an experimental subsample of adults (n = 155). Finally, in an independent sample of male twins (n = 1240, age 51-50 years), learning slope showed significant heritability. Within-session learning slope may be a useful marker beyond performance per se, being heritable and having unique predictive value for long-term memory function, hippocampal volume and training benefit across the human lifespan.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Walhovd KB,Bråthen ACS,Panizzon MS,Mowinckel AM,Sørensen Ø,de Lange AG,Krogsrud SK,Håberg A,Franz CE,Kremen WS,Fjell AMdoi
10.1038/s41598-020-78225-1subject
Has Abstractpub_date
2020-12-03 00:00:00pages
21158issue
1issn
2045-2322pii
10.1038/s41598-020-78225-1journal_volume
10pub_type
杂志文章abstract：:We fabricate high-performance, flexible, transparent electrochromic (EC) films and thin film heaters (TFHs) on an ITO/Cu/ITO (ICI) multilayer electrode prepared by continuous roll-to-roll (RTR) sputtering of ITO and Cu targets. The RTR-sputtered ICI multilayer on a 700 mm wide PET substrate at room temperature exhibit...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33868
更新日期：2016-09-22 00:00:00
abstract：:The North Sea is one of the most extensively studied marine regions of the world. Hence, large amounts of molecular data for species identification are available in public repositories, and expectations to find numerous new species in this well-known region are rather low. However, molecular reference data for harpact...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45718-7
更新日期：2019-06-24 00:00:00
abstract：:While considered an extracellular pathogen, Pseudomonas aeruginosa has been reported to be engulfed by macrophages in cellular and animal models. However, the role of macrophages in P. aeruginosa clearance in vivo remains poorly studied. The major outer membrane porin OprF has been recently shown to be involved in P. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79678-0
更新日期：2021-01-11 00:00:00
abstract：:Coleoptera (beetles) is a massively successful order of insects, distinguished by their evolutionarily modified forewings called elytra. These structures are often presumed to have been a major driving force for the successful radiation of this taxon, by providing beetles with protection against a variety of harsh env...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34813
更新日期：2016-10-06 00:00:00
abstract：:Triple-doped (Yb(3+)/Er(3+)/Tm(3+)) KMnF3 nanocubes with uniform sizes of 250 nm were synthesized by a facile hydrothermal route using the oleic acid as the capping agent. It was found that these nanocubes can simultaneously exhibited four-color (blue, green, red and NIR) upconversion emissions under a single 980 nm n...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17088
更新日期：2015-11-26 00:00:00
abstract：:Interleukin 17 (IL-17) stimulates the osteogenic differentiation of progenitor cells in vitro through a synergy with bone morphogenetic protein (BMP)-2. This study investigates whether the diverse responses mediated by IL-17 in vivo also lead to enhanced BMP-2-induced bone formation. Since IL-17 is known to induce ost...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25564-9
更新日期：2018-05-08 00:00:00
abstract：:Vitellogenin is the main yolk precursor protein in insect oocytes. It is synthesized in the fat body and released into the hemolymph. To reach the oocyte surface, vitellogenin must cross a single layer of follicular epithelium cells. The transport of vitellogenin across the follicular epithelium has been suggested to ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52789-z
更新日期：2019-11-11 00:00:00
abstract：:A fast-growing stalagmite from the central California coast provides a high-resolution record of climatic changes synchronous with global perturbations resulting from the catastrophic drainage of proglacial Lake Agassiz at ca. 8.2 ka. High frequency, large amplitude variations in carbon isotopes during the 8.2 ka even...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04215-5
更新日期：2017-06-20 00:00:00
abstract：:We propose an ultrathin metallic structure to produce frequency-selective spoof surface plasmon polaritons (SPPs) in the microwave and terahertz frequencies. Designed on a thin dielectric substrate, the ultrathin metallic structure is composed of two oppositely oriented single-side corrugated strips, which are coupled...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08165
更新日期：2015-02-02 00:00:00
abstract：:Bloodstain Pattern Analysis is a forensic discipline in which, among others, the position of victims can be determined at crime scenes on which blood has been shed. To determine where the blood source was investigators use a straight-line approximation for the trajectory, ignoring effects of gravity and drag and thus ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11461
更新日期：2015-06-22 00:00:00
abstract：:Mouse models have contributed to the bulk of knowledge on Systemic Lupus Erythematosus (SLE). Nevertheless, substantial differences exist between human and mouse immune system. We aimed to establish and characterise a SLE model mediated by human immune system. Injection of pristane into immunodeficient mice reconstitu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16999-7
更新日期：2017-11-30 00:00:00
abstract：:The aim of the present study was to evaluate the predictive value of 25-hydroxyvitamin D, calcium and parathormone level, co-existence of thyroid nodule, thyroidectomy history and adenoma volume on the success of neck ultrasound (US) and technetium-99m sestamibi (MIBI) scan in primary hyperparathyroidism (PHP) patient...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48536-z
更新日期：2019-08-19 00:00:00
abstract：:Despite numerous advances in genomics and bioinformatics, technological hurdles remain to examine host-microbe transcriptomics. Sometimes the transcriptome of either or both can be ascertained merely by generating more sequencing reads. However, many cases exist where bacterial mRNA needs to be enriched further to ena...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34850
更新日期：2016-10-07 00:00:00
abstract：:Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane. Loss of Caveolin-1 (Cav1) function in mice causes distinct neurological phenotypes leading to impaired motor control, however, the underlying developmental mechanisms are largely unknown. In...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73429-x
更新日期：2020-10-05 00:00:00
abstract：:Lambdoid craniosynostosis (LC) is a rare non-syndromic craniosynostosis characterised by fusion of the lambdoid sutures at the back of the head. Surgical correction including the spring assisted cranioplasty is the only option to correct the asymmetry at the skull in LC. However, the aesthetic outcome from spring assi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75747-6
更新日期：2020-10-29 00:00:00
abstract：:We study the dynamical Casimir-Polder force on a two-level atom with different initial states in the one-dimensional dielectric cavity with output coupling, and obtain the analytical expression of the expectation value of dynamical Casimir-Polder force. Results show that the expectation values of dynamical Casimir-Pol...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68546-6
更新日期：2020-07-20 00:00:00
abstract：:The opening of connexin (Cx) hemichannels in the membrane is tightly regulated by calcium (Ca2+) and membrane voltage. Electrophysiological and atomic force microscopy experiments indicate that Ca2+ stabilizes the hemichannel closed state. However, structural data show that Ca2+ binding induces an electrostatic seal p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15975-5
更新日期：2017-11-20 00:00:00
abstract：:Previous studies have demonstrated that patients with posttraumatic stress disorder (PTSD) caused by different types of trauma may show divergence in epidemiology, clinical manifestation and treatment outcome. However, it is still unclear whether this divergence has neuroanatomic correlates in PTSD brains. To elucidat...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析,评审
doi：10.1038/srep33748
更新日期：2016-09-21 00:00:00
abstract：:Ovarian tissue cryopreservation is considered as a useful option to preserve fertility for cancer patients. This study purposed to evaluate the change of telomere length and senescence markers during human ovarian tissue cryopreservation. Ovarian tissues were obtained from women who underwent benign ovarian surgery in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81973-3
更新日期：2021-01-26 00:00:00
abstract：:Broadband on-chip optical frequency combs (OFCs) are important for expanding the functionality of photonic integrated circuits. Here, we demonstrate a huge local optical nonlinearity enhancement using graphene. A waveguide is decorated with graphene by precisely manipulating graphene's area and position. Our approach ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45520
更新日期：2017-04-12 00:00:00
abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive immune-mediated joint deterioration. Current treatments are not antigen specific and are associated with various adverse. We have previously demonstrated that tolerogenic dendritic cells (Tol-DC) are potent antigen-specific immune regulato...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43188
更新日期：2017-02-23 00:00:00
abstract：:Optical resolution photoacoustic microscopy (OR-PAM) is a non-invasive, label-free method of in vivo imaging with microscopic resolution and high optical contrast. Based on intrinsic contrasts, OR-PAM has expanded to include in vivo vessel imaging, flow cytometry, physiological parameter analysis, and single-cell char...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13224-3
更新日期：2017-10-17 00:00:00
abstract：:The knee joint center of rotation is altered in the absence of the anterior cruciate ligament, which leads to substantially higher variance in kinematic patterns. To overcome this, total knee arthroplasty (TKA) designs with a high congruency in the lateral compartment have been proposed. The purpose of this study was ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45694-y
更新日期：2019-06-24 00:00:00
abstract：:Inhomogeneity in the ground state is an intriguing, emergent phenomenon in magnetism. Recently, it has been observed in the magnetostructural channel of the geometrically frustrated α-NaMnO2, for the first time in the absence of active charge degrees of freedom. Here we report an in-depth numerical and local-probe exp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09272
更新日期：2015-03-19 00:00:00
abstract：:The non-invasive high-resolution spatial mapping of cell metabolism within tissues could provide substantial advancements in assessing the efficacy of stem cell therapy and understanding tissue development. Here, using two-photon excited fluorescence microscopy, we elucidate the relationships among endogenous cell flu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03432
更新日期：2013-12-05 00:00:00
abstract：:Inhibition of the androgen receptor (AR) by second-generation anti-androgens is a standard treatment for metastatic castration resistant prostate cancer (mCRPC), but it inevitably leads to the development of resistance. Since the introduction of highly efficient AR signalling inhibitors, approximately 20% of mCRPC pat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50220-1
更新日期：2019-09-24 00:00:00
abstract：:The relationships between polypeptide composition, sequence, structure and function have been puzzling biologists ever since first protein sequences were determined. Here, we study the statistics of occurrence of all possible pentapeptide sequences in known proteins. To compensate for the non-uniform distribution of i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33433-8
更新日期：2018-10-11 00:00:00
abstract：:Effective population size reflects the history of population growth, contraction, and structuring. When the effect of structuring is negligible, the inferred trajectory of the effective population size can be informative about the key events in the history of a population. We used the IBDNe and DoRIS approaches, which...
journal_title：Scientific reports
pub_type： 历史文章,杂志文章
doi：10.1038/s41598-020-66734-y
更新日期：2020-06-16 00:00:00
abstract：:Sexual spores are important for the dispersal and population dynamics of fungi. They show remarkable morphological diversity, but the underlying forces driving spore evolution are poorly known. We investigated whether trophic status and substrate associations are associated with morphology in 787 macrofungal genera. W...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23292-8
更新日期：2018-03-29 00:00:00
abstract：:Because of the pathogenicity and low incidence of avian influenza virus infections in humans, the immune correlates of protection for avian influenza vaccines cannot be determined from clinical studies. Here, we used the ferret model to address this for an avian influenza H5N1 vaccine. Using oil-in-water adjuvants, we...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44727
更新日期：2017-03-17 00:00:00
