Abstract：
:Vitellogenin is the main yolk precursor protein in insect oocytes. It is synthesized in the fat body and released into the hemolymph. To reach the oocyte surface, vitellogenin must cross a single layer of follicular epithelium cells. The transport of vitellogenin across the follicular epithelium has been suggested to occur through the enlarged intercellular spaces (patency) by a paracellular route or by endocytosis by follicular cells and release onto oocyte surface in a transcelluar route. In this study, we investigated whether vitellogenin transport in the meroistic telotrophic ovary of Podisus nigrispinus (Hemiptera) occurs via a paracellular or transcellular route. Light and transmission electron microscopies showed that short cell-cell contacts with well-developed occluding septate junctions were present in follicular cells with patency. Immunofluorescence microscopy revealed the presence of vitellogenin receptors in the plasma membrane and of vitellogenin in the cytoplasm of follicular cells. Data suggest that cell-cell contacts serve as a barrier to large vitellogenin molecules and that this protein is transported via a transcellular route of receptor-mediated endocytosis.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Assis MQ,Dohanik VT,Oliveira LL,Zanuncio JC,Serrão JEdoi
10.1038/s41598-019-52789-zsubject
Has Abstractpub_date
2019-11-11 00:00:00pages
16441issue
1issn
2045-2322pii
10.1038/s41598-019-52789-zjournal_volume
9pub_type
杂志文章abstract：:Complex Semi-Definite Programming (SDP) is introduced as a novel approach to phase retrieval enabled control of monochromatic light transmission through highly scattering media. In a simple optical setup, a spatial light modulator is used to generate a random sequence of phase-modulated wavefronts, and the resulting i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02716-x
更新日期：2017-05-31 00:00:00
abstract：:Cholangiocarcinoma (CCA) represents a rare form of primary liver cancer with increasing incidence but dismal prognosis. Surgical treatment has remained the only potentially curative treatment option, but it remains unclear which patients benefit most from liver surgery, highlighting the need for new preoperative strat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17175-7
更新日期：2017-12-05 00:00:00
abstract：:The oral microflora is composed of both health-promoting as well as disease-initiating bacteria. Many of the disease-initiating bacteria are anaerobic and include organisms such as Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Tannerella forsythia. Here we investigated a novel therapeut...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09616-0
更新日期：2017-09-05 00:00:00
abstract：:PDA is a major cause of US cancer-related deaths. Oncogenic Kras presents in 90% of human PDAs. Kras mutations occur early in pre-neoplastic lesions but are insufficient to cause PDA. Other contributing factors early in disease progression include chronic pancreatitis, alterations in epigenetic regulators, and tumor s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77373-8
更新日期：2020-11-26 00:00:00
abstract：:The sequential paradigm of data acquisition and analysis in next-generation sequencing leads to high turnaround times for the generation of interpretable results. We combined a novel real-time read mapping algorithm with fast variant calling to obtain reliable variant calls still during the sequencing process. Thereby...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52991-z
更新日期：2019-11-11 00:00:00
abstract：:The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver operating characteristi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76352-3
更新日期：2020-11-09 00:00:00
abstract：:Formation-free multi-level resistive switching characteristics by using 10 nm-thick polycrystalline GeOx film in a simple W/GeOx/W structure and understanding of switching mechanism through redox reaction in H2O2/sarcosine sensing (or changing Ge°/Ge4+ oxidation states under external bias) have been reported for the f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11657-4
更新日期：2017-09-11 00:00:00
abstract：:The westerly wind burst (WWB) is an important triggering mechanism of El Niño and typically occurs in the western Pacific Ocean. The Fourier spectrum of the wind field over the western tropical Pacific is characterised by a large variety of peaks distributed from intra-seasonal to decadal time scales, suggesting that ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79655-7
更新日期：2021-01-13 00:00:00
abstract：:Norovirus is one of the most common causes of gastroenteritis. Following infection, anti-norovirus salivary immunoglobulin G (IgG) rises steeply within 2 weeks and remains elevated for several months; this immunoconversion can serve as an indicator of infection. We used a multiplex salivary immunoassay to study norovi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56040-7
更新日期：2019-12-20 00:00:00
abstract：:Burley tobacco (Nicotiana Tabacum) is a chlorophyll-deficiency mutant. Nitrate is one precursor of tobacco-specific nitrosamines (TSNAs) and is largely accumulated in burley tobacco. To decrease nitrate accumulation in burley tobacco, glycerol, a polyhydric alcohol compound and physiological regulating material, was s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31432-3
更新日期：2018-09-05 00:00:00
abstract：:Multi-stranded helices are widespread in nature. The interplay of polymeric properties with biological function is seldom discussed. This study probes analogies between structural and mechanical properties of collagen and DNA. We modeled collagen with Eulerian rotational and translational parameters of adjacent rungs ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12878-3
更新日期：2017-10-16 00:00:00
abstract：:A central goal of electronics based on correlated materials or 'Mottronics' is the ability to switch between distinct collective states with a control voltage. Small changes in structure and charge density near a transition can tip the balance between competing phases, leading to dramatic changes in electronic and mag...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01876
更新日期：2013-01-01 00:00:00
abstract：:The control for the processing of precursor liquids determines whether the properties and functions of the final material product can be engineered. An inherent challenge of processing viscous liquids arises from their large resistance to deform. Here, we report on the discovery of an electric approach that can signif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19606
更新日期：2016-02-10 00:00:00
abstract：:The clinical significance of STIM proteins and Orai Ca2+ channels in tumor progression has been demonstrated in different types of cancers. Podosomes are dynamic actin-rich cellular protrusions that facilitate cancer cell invasiveness by degrading extracellular matrix. Whether STIM1-dependent Ca2+ signaling facilitate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11273-2
更新日期：2017-09-14 00:00:00
abstract：:To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27143-4
更新日期：2018-06-13 00:00:00
abstract：:Life-history theory predicts that current behaviour affects future reproduction, implying that animals should optimise their escape strategies to reflect fitness costs and benefits of premature escape. Both costs and benefits of escape may change temporally with important consequences for the evolution of escape strat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32252-1
更新日期：2018-09-18 00:00:00
abstract：:We compared commercial kits for extraction of genomic DNA from the Gram-negative bacterium Klebsiella pneumoniae for subsequent Miseq sequencing. Purification of DNA was based on matrix binding (silica or anion exchange resin) or differential precipitation (salting out), respectively. The choice of extraction kit had ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28063
更新日期：2016-06-17 00:00:00
abstract：:Angiotensin II (AngII) promotes hypertension, atherogenesis, vascular aneurysm and impairs post-ischemic cardiac remodeling through concerted roles on vascular cells, monocytes and T lymphocytes. However, the role of AngII in B lymphocyte responses is largely unexplored. Here, we show that chronic B cell depletion (Ba...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04438-6
更新日期：2017-06-23 00:00:00
abstract：:A new synchrotron-based technique for elemental imaging that combines radiography and fluorescence spectroscopy has been developed and applied to study the spatial distribution of Ag, Zr and Mo in an Al alloy during heating and melting to 700, and then re-soldification. For the first time, multi-element distributions ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep15988
更新日期：2015-11-02 00:00:00
abstract：:A novel marine strain representing efficient degradation ability toward brown algae was isolated, identified, and assigned to Bacillus weihaiensis Alg07. The alga-associated marine bacteria promote the nutrient cycle and perform important functions in the marine ecosystem. The de novo sequencing of the B. weihaiensis ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38248
更新日期：2016-11-30 00:00:00
abstract：:Heavy metal pollution has been a problem since the advent of modern transportation, which despite efforts to curb emissions, continues to play a critical role in environmental pollution. Copper ions (Cu2+), in particular, are one of the more prevalent metals that have widespread detrimental ramifications. From this pe...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35565
更新日期：2016-10-18 00:00:00
abstract：:Green reduction of graphene oxide (GO) by phytochemicals was explored using the aqueous extract of kaffir lime peels. The research methods included preparation of extracts, preparation of GO, preparation and characterization of reduced-GO (RGO) using Fourier Transform Infrared (FTIR), X-ray diffraction (XRD), and UV-V...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-57433-9
更新日期：2020-01-20 00:00:00
abstract：:Nanophotonic circuitry requires an ability to externally control and analyze optical signals tightly confined in subwavelength volumes. Various schemes of surface plasmon (SP) routing have been presented using active and passive metasurfaces. One of the most appealing approaches is the use of plasmonic spin-orbit inte...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45513-4
更新日期：2019-06-20 00:00:00
abstract：:Given the speed of air travel, diseases even with a short viremia such as dengue can be easily exported to dengue naïve areas within 24 hours. We set out to estimate the risk of dengue virus introductions via travelers into Europe and number of secondary autochthonous cases as a result of the introduction. We applied ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22590-5
更新日期：2018-03-15 00:00:00
abstract：:Circuit QED on a chip has become a powerful platform for simulating complex many-body physics. In this report, we realize a Dicke-Ising model with an antiferromagnetic nearest-neighbor spin-spin interaction in circuit QED with a superconducting qubit array. We show that this system exhibits a competition between the c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04083
更新日期：2014-02-13 00:00:00
abstract：:Several studies have reported that weight control is of paramount importance in reducing the risk of metabolic syndrome. Nevertheless, this well-known association does not provide any practical information on how much weight loss in a given period would reduce the risk of metabolic syndrome in individuals in a persona...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67238-5
更新日期：2020-06-19 00:00:00
abstract：:The inconsistent findings on the association between COMT (catecholamine-O-methyl-transferase) and suicidal behaviour gave reason to choose a clear phenotype description of suicidal behaviour and take childhood maltreatment as environmental factor into account. The aim of this candidate-gene-association study was to e...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-19040-z
更新日期：2018-01-12 00:00:00
abstract：:Plant essential oils are considered as important bio-sources for the development of natural and environmentally safe pest control tools due to their multiple modes of action on insects. In this paper we have evaluated the activity of commercially available thyme oil and its constituents thymol, carvacrol, and p-cymene...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79550-1
更新日期：2021-01-13 00:00:00
abstract：:Global temperature changes have emphasized the need to understand how species adapt to thermal stress across their ranges. Genetic mechanisms may contribute to variation in thermal tolerance, providing evidence for how organisms adapt to local environments. We determine physiological thermal limits and characterize ge...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73391-8
更新日期：2020-10-13 00:00:00
abstract：:Cancer stem cells play an important role on tumor progression. Biomarkers of stem cell property and their relationship to extranodal involvement of malignant lymphocytes are undefined in diffuse large B-cell lymphoma (DLBCL). Here we showed that junctional adhesion molecule-A (JAM-A) was highly expressed in DLBCL pati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07964-5
更新日期：2017-08-07 00:00:00
