Abstract：
:Formation-free multi-level resistive switching characteristics by using 10 nm-thick polycrystalline GeOx film in a simple W/GeOx/W structure and understanding of switching mechanism through redox reaction in H2O2/sarcosine sensing (or changing Ge°/Ge4+ oxidation states under external bias) have been reported for the first time. Oxidation states of Ge0/Ge4+ are confirmed by both XPS and H2O2 sensing of GeOx membrane in electrolyte-insulator-semiconductor structure. Highly repeatable 1000 dc cycles and stable program/erase (P/E) endurance of >106 cycles at a small pulse width of 100 ns are achieved at a low operation current of 0.1 µA. The thickness of GeOx layer is found to be increased to 12.5 nm with the reduction of polycrystalline grain size of <7 nm after P/E of 106 cycles, which is observed by high-resolution TEM. The switching mechanism is explored through redox reaction in GeOx membrane by sensing 1 nM H2O2, which is owing to the change of oxidation states from Ge0 to Ge4+ because of the enhanced O2- ions migration in memory device under external bias. In addition, sarcosine as a prostate cancer biomarker with low concentration of 50 pM to 10 µM is also detected.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Samanta S,Rahaman SZ,Roy A,Jana S,Chakrabarti S,Panja R,Roy S,Dutta M,Ginnaram S,Prakash A,Maikap S,Cheng HM,Tsai LN,Qiu JT,Ray SKdoi
10.1038/s41598-017-11657-4subject
Has Abstractpub_date
2017-09-11 00:00:00pages
11240issue
1issn
2045-2322pii
10.1038/s41598-017-11657-4journal_volume
7pub_type
杂志文章abstract：:1-Aminocyclopropane-1-carboxylic acid (ACC) is a precursor molecule of ethylene whose concentration is elevated in the plant subjected to biotic and abiotic stress. Several soil microorganisms are reported to produce ACC deaminase (ACCd) which degrades ACC thereby reducing stress ethylene in host plants. This study is...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35565-3
更新日期：2018-11-30 00:00:00
abstract：:The major source of ATP in cancer cells remains unclear. Here, we examined energy metabolism in gastric cancer cells and found increased fatty acid oxidation and increased expression of ALDH3A1. Metabolic analysis showed that lipid peroxidation by reactive oxygen species led to spontaneous production of 4-hydroxynonen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52814-1
更新日期：2019-11-08 00:00:00
abstract：:It is well known that haem serves as the prosthetic group of various haemoproteins that function in oxygen transport, respiratory chain, and drug metabolism. However, much less is known about the functions of the catabolites of haem in mammalian cells. Haem is enzymatically degraded to iron, carbon monoxide (CO), and ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10488
更新日期：2015-05-20 00:00:00
abstract：:This study examines the analytical and numerical solution of electromagnetic surface waves supported by a resistive metasurface-covered grounded metamaterial structure. To simulate the metamaterial, the Kramers-Kronig relation based on the causality principle is used, while the modeling of the resistive metasurface ha...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72396-7
更新日期：2020-09-23 00:00:00
abstract：:The critical importance of human milk to infants and even human civilization has been well established. Yet our understanding of the milk microbiome has been limited to cataloguing OTUs and computation of community diversity. To the best of our knowledge, there has been no report on the bacterial interactions within t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08275
更新日期：2015-02-05 00:00:00
abstract：:During bacterial infections, damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) activate immune cells. Here, we investigated whether plasma and sputum levels of High Mobility Group Box 1 (HMGB1), a prototypic DAMP, are associated with disease severity and aetiology in commu...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-018-31504-4
更新日期：2018-09-07 00:00:00
abstract：:The starch granule is Nature's way to store energy in green plants over long periods. Irrespective of their origins, starches display distinct structural features that are the fingerprints of levels of organization over six orders of magnitude. We hypothesized that Nature retains hierarchical material structures at al...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72218-w
更新日期：2020-11-18 00:00:00
abstract：:The proteins AtSEOR1 and AtSEOR2 occur as conjugates in the form of filaments in sieve elements of Arabidopsis thaliana. A reduced phytoplasma titre found in infected defective-mutant Atseor1ko plants in previous work raised the speculation that non-conjugated SEOR2 is involved in the phytohormone-mediated suppression...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71660-0
更新日期：2020-09-08 00:00:00
abstract：:The development of effective central nervous system (CNS) drugs has been hampered by the lack of robust strategies to mimic the blood-brain barrier (BBB) and cerebrovascular impairments in vitro. Recent technological advancements in BBB modeling using induced pluripotent stem cells (iPSCs) allowed to overcome some of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52213-6
更新日期：2019-11-05 00:00:00
abstract：:The aim of this study was to estimate the incidence of T2DM in three population groups: rural, rural-to-urban migrants and urban dwellers. Data from the PERU MIGRANT Study was analysed. The baseline assessment was conducted in 2007-2008 using a single-stage random sample and further follow-up was undertaken in 2015-16...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23812-6
更新日期：2018-04-03 00:00:00
abstract：:Ichthyoarchaeological evidence is uncommon at ancient hunter-gatherer sites from various regions and timeframes. This research contributes to the development of microarchaeological techniques useful for identifying fishing economies in situations where classifiable bones are unavailable. Specifically, traces of heat a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03737-2
更新日期：2017-06-15 00:00:00
abstract：:Protein phosphorylation is an important type of post-translational modification that is involved in a variety of biological activities. Most phosphorylation events occur on serine, threonine and tyrosine residues in eukaryotes. In recent years, many phosphorylation sites have been identified as a result of advances in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24735
更新日期：2016-04-19 00:00:00
abstract：:CRISPR-Cas9 is a powerful new tool for genome editing, but this technique creates mosaic mutations that affect the efficiency and precision of its ability to edit the genome. Reducing mosaic mutations is particularly important for gene therapy and precision genome editing. Although the mechanisms underlying the CRSIPR...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42081
更新日期：2017-02-03 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-68128-6
更新日期：2020-07-06 00:00:00
abstract：:The authors present the preparation procedure and a computational model of a three-layered fibrous scaffold for prolonged drug release. The scaffold, produced by emulsion/sequential electrospinning, consists of a poly(D,L-lactic-co-glycolic acid) (PLGA) fiber layer sandwiched between two poly(ε-caprolactone) (PCL) lay...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68117-9
更新日期：2020-07-07 00:00:00
abstract：:Influenza virus is a significant cause of morbidity and mortality, with worldwide seasonal epidemics. The duration and quality of humoral immunity and generation of immunological memory to vaccines is critical for protective immunity. In the current study, we examined the long-lasting protective efficacy of chimeric V...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40226
更新日期：2017-01-09 00:00:00
abstract：:Risk of hospital readmission and cardiac mortality increases with atmospheric pollution for patients with heart failure. The underlying mechanisms are unclear. Carbon monoxide (CO) a ubiquitous environmental pollutant could be involved. We explored the effect of daily exposure of CO relevant to urban pollution on post...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39715
更新日期：2017-01-03 00:00:00
abstract：:Bacteriophage T7 is an intracellular parasite that recognizes its host via its tail and tail fiber proteins, known as receptor-binding proteins (RBPs). The RBPs attach to specific lipopolysaccharide (LPS) features on the host. Various studies have shown expansion of the phage's host range via mutations in the genes en...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-57221-0
更新日期：2020-01-15 00:00:00
abstract：:In this study, a model assisted strategy is developed to control the distribution of colloids in porous media in the framework of nanoremediation, an innovative environmental nanotechnology aimed at reclaiming contaminated aquifers. This approach is exemplified by the delivery of humic acid-stabilized iron oxide nanop...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13423-y
更新日期：2017-10-11 00:00:00
abstract：:Recent evidence suggests that some seizures are preceded by preictal changes that start from minutes to hours before an ictal event. Nevertheless an adequate statistical evaluation in a large database of continuous multiday recordings is still missing. Here, we investigated the existence of preictal changes in long-te...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep04545
更新日期：2014-04-01 00:00:00
abstract：:Pinellia (Pinellia ternata (Thunb.) Breit.), as important medicinal plant, has been used to treat various ailments for a long time. The sixteen ploid plant (2n = 16 * 13 = 208) Pinellia T2Plus line was obtained from an octoploid (2n = 8 * 13 = 104) T2 line by chromosome-doubling technique. Compared with T2 line, the c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61512-2
更新日期：2020-03-12 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-36257-8
更新日期：2018-11-27 00:00:00
abstract：:The arbitrary control of the polarization states of light has attracted the interest of the scientific community because of the wide range of modern optical applications that such control can afford. However, conventional polarization control setups are bulky and very often operate only within a narrow wavelength rang...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18106
更新日期：2015-12-15 00:00:00
abstract：:To compare the different features of necrotizing pneumonia (NP) and non-NP (NNP) caused by Mycoplasma pneumoniae pneumonia (MPP) with large pulmonary lesions, and explore the predictor for NP to differentiate from MPP. A retrospective study of MPP patients with large pulmonary lesions hospitalized from January 2008 to...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76083-5
更新日期：2020-11-04 00:00:00
abstract：:We introduce a polarization-resolved terahertz time-domain spectrometer with a broadband (0.3-2.5 THz), rotatable THz polarization state, and which exhibits minimal change in the electric field amplitude and polarization state upon rotation. This was achieved by rotating an interdigitated photoconductive emitter, and ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12568-0
更新日期：2017-09-26 00:00:00
abstract：:Peak heat flow occurs at mid-ocean ridges and decreases with the age of the oceanic lithosphere. Several plate models, including the Parsons and Sclater (PSM) model, Global Depth and Heat (GDH1) model and Constant Heat flow Applied on the Bottom Lithospheric Isotherm (CHABLIS) model, have been used to predict heat flo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19167
更新日期：2016-01-13 00:00:00
abstract：:The coincidence of flood flows in a mainstream and its tributaries may lead to catastrophic floods. In this paper, we investigated the flood coincidence risk under nonstationary conditions arising from climate changes. The coincidence probabilities considering flood occurrence dates and flood magnitudes were calculate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60264-3
更新日期：2020-02-25 00:00:00
abstract：:Infection of humans with Chlamydia trachomatis, a bacterial pathogen with a unique intracellular replication cycle, may cause a variety of clinical manifestations. These are linked to various serovars of the pathogen; trachoma to serovars A-C, oculogenital infections to serovars D-K, and lymphogranuloma venereum to se...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54886-5
更新日期：2019-12-04 00:00:00
abstract：:Knowledge of the structure-property-function relationship of humic substances (HSs) is key for understanding their role in soil. Despite progress, studies on this topic are still under discussion. We analyzed 37 humic fractions with respect to their isotopic composition, structural characteristics, and properties resp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20798
更新日期：2016-02-10 00:00:00
abstract：:Bacterial β-glucuronidase (GUS) enzymes cause drug toxicity by reversing Phase II glucuronidation in the gastrointestinal tract. While many human gut microbial GUS enzymes have been examined with model glucuronide substrates like p-nitrophenol-β-D-glucuronide (pNPG), the GUS orthologs that are most efficient at proces...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36069-w
更新日期：2019-01-29 00:00:00
