Abstract：
:The starch granule is Nature's way to store energy in green plants over long periods. Irrespective of their origins, starches display distinct structural features that are the fingerprints of levels of organization over six orders of magnitude. We hypothesized that Nature retains hierarchical material structures at all levels and that some general rules control the morphogenesis of these structures. We considered the occurrence of a «phyllotaxis» like features that would develop at scales ranging from nano to micrometres, and developed a novel geometric model capable of building complex structures from simple components. We applied it, according to the Fibonacci Golden Angle, to form several Golden Spirals, and derived theoretical models to simulate scattering patterns. A GSE, constructed with elements made up of parallel stranded double-helices, displayed shapes, sizes and high compactness reminiscent of the most intriguing structural element: the 'blocklet'. From the convergence between the experimental findings and the theoretical construction, we suggest that the «phyllotactic» model represents an amylopectin macromolecule, with a high molecular weight. Our results offer a new vision to some previous models of starch. They complete a consistent description of the levels of organization over four orders of magnitude of the starch granule.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Spinozzi F,Ferrero C,Perez Sdoi
10.1038/s41598-020-72218-wsubject
Has Abstractpub_date
2020-11-18 00:00:00pages
20093issue
1issn
2045-2322pii
10.1038/s41598-020-72218-wjournal_volume
10pub_type
杂志文章abstract：:Brain metastasis is a significant unmet clinical problem in breast cancer treatment. It is always associated with poor prognosis and high morbidity. Recently, Slit2/Robo1 pathway has been demonstrated to be involved in the progression of breast carcinoma. However, until present, there are no convincing reports that su...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14430
更新日期：2015-09-24 00:00:00
abstract：:Prosthesis embodiment, the perception of a prosthesis as part of one's body, may be an important component of functional recovery for individuals with upper limb absence. This work determined whether embodiment differs between body-powered and myoelectric prosthesis users. In a sample of nine individuals with transrad...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72470-0
更新日期：2020-09-22 00:00:00
abstract：:The identification of the modes of action of bioactive compounds is a major challenge in chemical systems biology of diseases. Genome-wide expression profiling of transcriptional responses to compound treatment for human cell lines is a promising unbiased approach for the mode-of-action analysis. Here we developed a n...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40164
更新日期：2017-01-10 00:00:00
abstract：:The concept of remission for patients with inflammatory bowel diseases has recently evolved, and should also include histological healing of the mucosa, difficult to evaluate since there is no agreement on pathological scores and those available are quite complex to use in the daily routine. We evaluated the possible ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07338-x
更新日期：2017-07-28 00:00:00
abstract：:Homologous recombination (HR) events are key drivers of cancer-promoting mutations, and the ability to visualize these events in situ provides important information regarding mutant cell type, location, and clonal expansion. We have previously created the Rosa26 Direct Repeat (RaDR) mouse model wherein HR at an integr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30557-9
更新日期：2018-08-14 00:00:00
abstract：:Several cobalt-based Heusler alloys have been predicted to exhibit Weyl Semimetal behavior due to time reversal symmetry breaking. Co2TiGe is one of the predicted ferromagnetic Weyl semimetals. In this work, we report weak localization and small anomalous Hall conductivity in half-metallic Co2TiGe thin films grown by ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39037-0
更新日期：2019-03-04 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-34062-x
更新日期：2018-10-29 00:00:00
abstract：:We compared commercial kits for extraction of genomic DNA from the Gram-negative bacterium Klebsiella pneumoniae for subsequent Miseq sequencing. Purification of DNA was based on matrix binding (silica or anion exchange resin) or differential precipitation (salting out), respectively. The choice of extraction kit had ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28063
更新日期：2016-06-17 00:00:00
abstract：:Cysteine based silver-gold nanocomposite (Cys/Ag-Au NCz) was synthesized, this was followed by its characterization using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Ultraviolet-visible spectroscopy (UV-Vis), Scanning electron microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDAX), ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-57181-5
更新日期：2020-01-14 00:00:00
abstract：:In sugarcane (Saccharum spp. hybrid) breeding, introgression of useful genes via intergeneric hybridization is a powerful strategy for improving the crop productivity. Erianthus arundinaceus shows great potential in terms of useful traits; however, little is known about the cytogenetic and agronomic characteristics of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38316-6
更新日期：2019-02-11 00:00:00
abstract：:The precision and efficiency of the registration of megavolt-level electronic portal imaging devices (EPID) images with the naked eye in the orthogonal window are reduced. This study aims to develop a new registration algorithm with enhanced accuracy and efficiency. Ten setup errors with different translation and rota...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67331-9
更新日期：2020-06-24 00:00:00
abstract：:Short QT syndrome (SQTS) is a rare condition characterized by abnormally 'short' QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death. This simulation study investigated arrhythmia dynamics in multi-scale human ventricle models associated with the SQT2-related V307L KCNQ1 'gain-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08367-2
更新日期：2017-08-16 00:00:00
abstract：:Dark septate endophytes (DSE) are a form-group of root endophytic fungi with elusive functions. Here, the genomes of two common DSE of semiarid areas, Cadophora sp. and Periconia macrospinosa were sequenced and analyzed with another 32 ascomycetes of different lifestyles. Cadophora sp. (Helotiales) and P. macrospinosa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24686-4
更新日期：2018-04-20 00:00:00
abstract：:Engineered nanomaterials hold great promise for the future development of innovative products but their adverse health effects are a major concern. Recent studies have indicated that certain nanomaterials, including carbon nanotubes (CNTs), may be carcinogenic. However, the underlying mechanisms behind their potential...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12037-8
更新日期：2017-09-14 00:00:00
abstract：:Drug-resistant bacteria represent a significant global threat. Given the dearth of new antibiotics, host-directed therapies (HDTs) are especially desirable. As IFN-gamma (IFNγ) plays a central role in host resistance to intracellular bacteria, including Mycobacterium tuberculosis, we searched for small molecules to au...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24409
更新日期：2016-04-18 00:00:00
abstract：:Marigold (Tagetes erecta L.) is an important ornamental plant with a wide variety of flower colors. Despite its economic value, few biochemical and molecular studies have explored the generation of flower color in this species. To study the mechanism underlying marigold petal color, we performed a metabolite analysis ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73859-7
更新日期：2020-10-08 00:00:00
abstract：:There are a number of psychological phenomena in which dramatic emotional responses are evoked by seemingly innocuous perceptual stimuli. A well known example is the 'uncanny valley' effect whereby a near human-looking artifact can trigger feelings of eeriness and repulsion. Although such phenomena are reasonably well...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00864
更新日期：2012-01-01 00:00:00
abstract：:Age-specific genetic and antigenic variations of influenza viruses have not been documented in tropical and subtropical regions. We implemented a systematic surveillance program in two tertiary hospitals in Hong Kong Island, to collect 112 A(H1N1)pdm09 and 254 A(H3N2) positive specimens from 2013 to 2014. Of these, 56...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30260
更新日期：2016-07-25 00:00:00
abstract：:The estrogenicity of parabens at human exposure levels has become a focus of concern due to the debate over whether the estrogenicity of parabens is strong enough to play a role in the increased incidence of breast cancer. In this study, the uterotrophic activities of methylparaben (MP) and ethylparaben (EP) at doses ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25173
更新日期：2016-04-28 00:00:00
abstract：:The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8-10 mm), Grade C (5-8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81339-9
更新日期：2021-01-19 00:00:00
abstract：:Gram-positive bacteria homeostasis and antibiotic resistance mechanisms are dependent on the intricate architecture of the cell wall, where amidated peptidoglycan plays an important role. The amidation reaction is carried out by the bi-enzymatic complex MurT-GatD, for which biochemical and structural information is ve...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-22986-3
更新日期：2018-03-28 00:00:00
abstract：:Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that class IA PI3K-mediated signals induce the expression of the transcription factor Pax5, which pl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19460-5
更新日期：2018-01-22 00:00:00
abstract：:The F1F0-ATP synthase, an enzyme complex, is mainly located on the mitochondrial inner membrane or sometimes cytomembrane to generate or hydrolyze ATP, play a role in cell proliferation. This study focused on the role of F1F0-ATP synthase in keratinocyte differentiation, and its relationship with intracellular and ext...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42672
更新日期：2017-02-17 00:00:00
abstract：:Quantum Zeno effect shows that frequent observations can slow down or even stop the unitary time evolution of an unstable quantum system. This effect can also be regarded as a physical consequence of the statistical indistinguishability of neighboring quantum states. The accessibility of quantum Zeno dynamics under un...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11509
更新日期：2015-06-23 00:00:00
abstract：:Previous analyses of the Atlantic cod genome showed unique combinations of lacking and expanded number of genes for the immune system. The present study examined lysozyme activity, lysozyme gene distribution and expression in cod. Enzymatic assays employing specific bacterial lysozyme inhibitors provided evidence for ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28318
更新日期：2016-06-21 00:00:00
abstract：:Present study, for the first time, reports the development of a nanohybridized baculovirus based stent that can locally promote vascular re-endothelialization by efficient delivery of pro-angiogenic vascular endothelial growth factor (Vegf) genes. In vitro data demonstrated rapid expression of functionally active Vegf...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02366
更新日期：2013-01-01 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-59303-w
更新日期：2020-02-06 00:00:00
abstract：:PageRank is arguably the most popular ranking algorithm which is being applied in real systems ranging from information to biological and infrastructure networks. Despite its outstanding popularity and broad use in different areas of science, the relation between the algorithm's efficacy and properties of the network ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16181
更新日期：2015-11-10 00:00:00
abstract：:Dosimetry models using preclinical positron emission tomography (PET) data are commonly employed to predict the clinical radiological safety of novel radiotracers. However, unbiased clinical safety profiling remains difficult during the translational exercise from preclinical research to first-in-human studies for nov...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72830-w
更新日期：2020-09-29 00:00:00
abstract：:Free carriers, polarons (P), in conjugated polymers play a key role in the performance of optoelectronic devices. Here, we present solid evidence that P can be predominantly generated from polaron pairs (PP) in a poly(3-hexylthiophene) (P3HT) film under zero electric field. P formation from PP strongly depends on temp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08436
更新日期：2015-02-13 00:00:00
