Abstract:
:To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT 690 from GE Healthcare. The scanning parameters were the same with the ones to be used in the planned trial. The 18F-NaF concentration in the background was 5.3 kBq/ml, while the ones in the spheres of diameter 37 mm, 22 mm, 17 mm and 10 mm were 8:1 as to that of the background and the ones in the spheres of diameter 28 mm and 13 mm were 0 kBq/ml. The consistency of hot sphere recovery coefficient (HRC), cold sphere recovery coefficient (CRC), hot sphere contrast (QH) and cold sphere contrast (Qc) among these 8 PET/CTs was analyzed. The variation of the main quantitative parameters of the eight PET/CT systems was within 10%, which is acceptable for the clinical trial.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhu Y,Geng C,Huang J,Liu J,Wu N,Xin J,Xu H,Yu L,Geng Jdoi
10.1038/s41598-018-27143-4subject
Has Abstractpub_date
2018-06-13 00:00:00pages
9035issue
1issn
2045-2322pii
10.1038/s41598-018-27143-4journal_volume
8pub_type
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