STIM1-dependent Ca2+ signaling regulates podosome formation to facilitate cancer cell invasion.

abstract：:Maize streak virus disease (MSVD), caused by Maize streak virus (MSV; genus Mastrevirus), is one of the most severe and widespread viral diseases that adversely reduces maize yield and threatens food security in Africa. An effective control and management of MSVD requires robust and sensitive diagnostic tests capable ...

journal_title：Scientific reports

authors： Tembo M,Adediji AO,Bouvaine S,Chikoti PC,Seal SE,Silva G

更新日期：2020-11-12 00:00:00

abstract：:Facial emotion perception plays a key role in interpersonal communication and is a precursor for a variety of socio-cognitive abilities. One brain region thought to support emotion perception is the inferior frontal cortex (IFC). The current study aimed to examine whether modulating neural activity in the IFC using hi...

journal_title：Scientific reports

authors： Penton T,Dixon L,Evans LJ,Banissy MJ

更新日期：2017-09-12 00:00:00

abstract：:Respiratory sensations such as breathlessness are prevalent in many diseases and are amplified by increased levels of anxiety. Cortical activation in response to inspiratory occlusions in high- and low-anxious individuals was found different in previous studies using the respiratory-related evoked potential method. Ho...

journal_title：Scientific reports

authors： Chan PS,Wu YT,Hsu AL,Li CW,Wu CW,von Leupoldt A,Hsu SC

更新日期：2019-10-21 00:00:00

abstract：:In this study, we measured the human epidermal growth factor receptor 2 (HER2) copy number in both tissue and plasma samples of gastric cancer patients by using droplet digital polymerase chain reaction (ddPCR) method. Eighty gastric cancer patients were enrolled and both formalin-fixed and paraffin-embedded tissue an...

journal_title：Scientific reports

authors： Kim B,Nam SK,Seo SH,Park KU,Ahn SH,Park DJ,Kim HH,Kim WH,Lee HS

更新日期：2020-03-06 00:00:00

abstract：:Food thickening agents are used to aid the administration of medicine to elderly patients with dysphagia. Magnesium oxide tablets are sometimes administered with food thickening agents. Non-disintegration and disintegration delay of these tablets in the body are problems associated with food thickening agent use. Howe...

journal_title：Scientific reports

authors： Matsuo T,Sato A,Kudo K,Sadzuka Y,Tomita T

更新日期：2020-09-30 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found that the proteasome...

journal_title：Scientific reports

authors： Ren H,Li F,Tian C,Nie H,Wang L,Li HH,Zheng Y

更新日期：2015-10-28 00:00:00

abstract：:Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. However, the TM4SF1-associated signaling network in metastasis remains unknown. In the present study, we found that TM4SF1 affected the format...

journal_title：Scientific reports

authors： Yang JC,Zhang Y,He SJ,Li MM,Cai XL,Wang H,Xu LM,Cao J

更新日期：2017-04-03 00:00:00

abstract：:Predation has driven the evolution of diverse adaptations for defence among prey, and one striking example is the deimatic display. While such displays can resemble, or indeed co-occur with, aposematic 'warning' signals, theory suggests deimatic displays may function independently of predator learning. The survival va...

journal_title：Scientific reports

authors： Umbers KDL,White TE,De Bona S,Haff T,Ryeland J,Drinkwater E,Mappes J

更新日期：2019-01-24 00:00:00

abstract：:Spin-polarized triangular graphene nanoflakes (t-GNFs) serve as ideal building blocks for the long-desired ferromagnetic graphene superlattices, but they are always assembled to planar structures which reduce its mechanical properties. Here, by joining t-GNFs in a spiral way, we propose one-dimensional graphene spiral...

journal_title：Scientific reports

authors： Zhang X,Zhao M

更新日期：2014-07-16 00:00:00

abstract：:The ability of marine invertebrate larvae to control their vertical position shapes their dispersal pattern. In species characterized by large variations in population density, like many echinoderm species, larval dispersal may contribute to outbreak and die-off phenomena. A proliferation of the ophiuroid Ophiocomina ...

journal_title：Scientific reports

authors： Guillam M,Bessin C,Blanchet-Aurigny A,Cugier P,Nicolle A,Thiébaut É,Comtet T

更新日期：2020-07-21 00:00:00

abstract：:Epidemiologic studies have identified a positive association between obesity and colorectal neoplasia. Adiposity induces systemic low-grade inflammation, which is commonly assessed with a sensitive biomarker, C-reactive protein (CRP). To understand the molecular mechanisms of obesity in the etiology of colorectal neop...

journal_title：Scientific reports

authors： Kigawa N,Budhathoki S,Yamaji T,Iwasaki M,Inoue M,Tsugane S

更新日期：2017-06-30 00:00:00

abstract：:Evaluation of facial asymmetry generally involves landmark-based analyses that cannot intuitively assess differences in three-dimensional (3D) stereoscopic structures between deviation and non-deviation sides. This study tested a newly developed similarity index that uses a mirroring technique to intuitively evaluate ...

journal_title：Scientific reports

authors： Kwon SM,Hwang JJ,Jung YH,Cho BH,Lee KJ,Hwang CJ,Choi SH

更新日期：2019-07-29 00:00:00

abstract：:The striped venus (Chamelea gallina) is an important economic resource in the Mediterranean Basin; this species has exhibited a strong quantitative decline in the Adriatic Sea. The aim of this work was to provide a comprehensive view of the biological status of C. gallina to elucidate the bioecological characteristics...

journal_title：Scientific reports

authors： Carducci F,Biscotti MA,Trucchi E,Giuliani ME,Gorbi S,Coluccelli A,Barucca M,Canapa A

更新日期：2020-11-05 00:00:00

abstract：:Beta oscillations observed in motor cortical local field potentials (LFPs) recorded on separate electrodes of a multi-electrode array have been shown to exhibit non-zero phase shifts that organize into planar waves. Here, we generalize this concept to additional classes of salient patterns that fully describe the spat...

journal_title：Scientific reports

authors： Denker M,Zehl L,Kilavik BE,Diesmann M,Brochier T,Riehle A,Grün S

更新日期：2018-03-26 00:00:00

abstract：:Pseudomonas aeruginosa is an opportunistic pathogen and a leading cause of nosocomial infections. Unfortunately, P. aeruginosa has low antibiotic susceptibility due to several chromosomally encoded antibiotic resistance genes. Hence, we carried out mechanistic studies to determine how azithromycin affects quorum sensi...

journal_title：Scientific reports

authors： Zeng J,Zhang N,Huang B,Cai R,Wu B,E S,Fang C,Chen C

更新日期：2016-04-14 00:00:00

abstract：:Most of the artificial low-pressure plasmas contact with physical walls in laboratories; the plasma loss at the wall significantly affects the plasma device performance, e.g., an electric propulsion device. Near the surface of the wall, ions are spontaneously accelerated by a sheath and deliver their momentum and ener...

journal_title：Scientific reports

authors： Takahashi K,Sugawara T,Ando A

更新日期：2020-01-23 00:00:00

abstract：:The dominant seagrass in Port Phillip Bay (PPB), Australia, Zostera nigricaulis, declined between 2000 and 2011, coinciding with the 'Millennium drought' that ended in 2009. These seagrasses are nitrogen-limited, underpinning the need to develop nitrogen budgets for better ecosystem management. Environmentally realist...

journal_title：Scientific reports

authors： Nayar S,Loo MGK,Tanner JE,Longmore AR,Jenkins GP

更新日期：2018-11-21 00:00:00

abstract：:Atropine eye drops and myopic retinal defocus each slow progression of myopia (short-sight). They also cause thickening of the choroid, and it has been suggested that the thickening is a precursor for reduced eye growth and slowed myopia progression. We investigated whether choroidal thickening due to optical defocus ...

journal_title：Scientific reports

authors： Chiang ST,Turnbull PRK,Phillips JR

更新日期：2020-10-27 00:00:00

abstract：:To assess the prevalence of cataract and cataract surgery in a population from Russia, we conducted the population-based Ural Eye and Medical Study with 5899 participants (80.5% out of 7328 eligible individuals), with an age of 40 + years as the eligibility criterion. In the phakic population, the prevalence of nuclea...

journal_title：Scientific reports

authors： Bikbov MM,Kazakbaeva GM,Gilmanshin TR,Zainullin RM,Nuriev IF,Zaynetdinov AF,Israfilova GZ,Panda-Jonas S,Arslangareeva II,Rakhimova EM,Rusakova IA,Jonas JB

更新日期：2020-10-23 00:00:00

abstract：:The effect of intravenous fluids (IVF) has been investigated clinically through the assessment of post-treatment reactions. However, the responses to IVF vary from patient-to-patient. It is important to understand the response of IVF treatment to be able to provide optimal IVF care. Herein, we investigated the impact ...

journal_title：Scientific reports

authors： Karamahmutoglu H,Altay A,Vural S,Elitas M

更新日期：2020-07-16 00:00:00

abstract：:RAS genotyping is mandatory to predict anti-EGFR monoclonal antibodies (mAbs) therapy resistance and BRAF genotyping is a relevant prognosis marker in patients with metastatic colorectal cancer. Although the role of hotspot mutations is well defined, the impact of uncommon mutations is still unknown. In this study, we...

journal_title：Scientific reports

authors： Franczak C,Kandathil SM,Gilson P,Husson M,Rouyer M,Demange J,Leroux A,Merlin JL,Harlé A

更新日期：2019-05-08 00:00:00

abstract：:Enhancers play a crucial role in gene regulation but the participation of enhancer transcripts (i.e. enhancer RNA, eRNAs) in regulatory systems remains unclear. We provide a computational analysis on eRNAs using genome-wide data across 12 mouse tissues. The expression of genes targeted by transcribing enhancer is posi...

journal_title：Scientific reports

authors： Cheng JH,Pan DZ,Tsai ZT,Tsai HK

更新日期：2015-07-29 00:00:00

abstract：:Energy metabolism, involving the ATP-dependent AMPK-PgC-Ppar pathway impacts metabolic health immensely, in that its impairment can lead to obesity, giving rise to disease. Based on observations that individuals with Gilbert's syndrome (GS; UGT1A1(*)28 promoter mutation) are generally lighter, leaner and healthier tha...

journal_title：Scientific reports

authors： Mölzer C,Wallner M,Kern C,Tosevska A,Schwarz U,Zadnikar R,Doberer D,Marculescu R,Wagner KH

更新日期：2016-07-21 00:00:00

abstract：:Two new indolizidine alkaloids crepidatumines A (1) and B (2) together with the stereoisomer of dendrocrepidine B (3) and known analog dendrocrepine (4) were isolated from D. crepidatum. Their structures were determined by HR-ESI-MS, NMR, and Electronic Circular Dichroism (ECD) experiments together with comparison of ...

journal_title：Scientific reports

authors： Xu X,Chen X,Yang R,Li Z,Zhou H,Bai Y,Yu M,Li B,Ding G

更新日期：2020-06-12 00:00:00

abstract：:Neurogenesis of hippocampal granule cells (GCs) persists throughout mammalian life and is important for learning and memory. How newborn GCs differentiate and mature into an existing circuit during this time period is not yet fully understood. We established a method to visualize postnatally generated GCs in organotyp...

journal_title：Scientific reports

authors： Radic T,Jungenitz T,Singer M,Beining M,Cuntz H,Vlachos A,Deller T,Schwarzacher SW

更新日期：2017-03-03 00:00:00

abstract：:Knee osteoarthritis (KOA) is reported to have characteristic kinematics during walking. However, the relationship between Kellgren-Lawrence (K/L) score and the 3D kinematic gait of patients with medial KOA remains unclear. Here, ninety-seven patients with medial KOA and thirty-eight asymptomatic participants were invo...

journal_title：Scientific reports

authors： Zeng X,Ma L,Lin Z,Huang W,Huang Z,Zhang Y,Mao C

更新日期：2017-06-22 00:00:00

abstract：:Bile acid (BA) signatures are altered in many disease states. BA metabolism is an important microbial function to assist gut colonization and persistence, as well as microbial survival during gastro intestinal (GI) transit and it is an important criteria for potential probiotic bacteria. Microbes that express bile sal...

journal_title：Scientific reports

authors： Prete R,Long SL,Gallardo AL,Gahan CG,Corsetti A,Joyce SA

更新日期：2020-01-24 00:00:00

abstract：:The moist savanna zone covers 0.5 × 106 km2 in West Africa and is characterized by very low soil N levels limiting primary production, but the ecology of nitrifiers in these (agro)ecosystems is largely unknown. We compared the effects of six agricultural practices on nitrifier activity, abundance and diversity at nine...

journal_title：Scientific reports

authors： Assémien FL,Pommier T,Gonnety JT,Gervaix J,Le Roux X

更新日期：2017-08-31 00:00:00

abstract：:It is estimated from twin studies that heritable factors account for at-least half of asthma-risk, of which genetic variants identified through population studies explain only a small fraction. Multi-generation large families with high asthma prevalence can serve as a model to identify highly penetrant genetic variant...

journal_title：Scientific reports

authors： Chakraborty S,Dakle P,Sinha A,Vishweswaraiah S,Nagori A,Salimath S,Prakash YS,Lodha R,Kabra SK,Ghosh B,Faruq M,Mahesh PA,Agrawal A

更新日期：2019-12-13 00:00:00

abstract：:Core flood and field tests have demonstrated that decreasing injection water salinity increases oil recovery from sandstone reservoirs. However, the microscopic mechanism behind the effect is still under debate. One hypothesis is that as salinity decreases, expansion of the electrical double layer decreases attraction...

journal_title：Scientific reports

authors： Hilner E,Andersson MP,Hassenkam T,Matthiesen J,Salino PA,Stipp SL

更新日期：2015-04-22 00:00:00