Appropriate usage of food thickening agents to prevent non-disintegration of magnesium oxide tablets.

abstract：:Agriculture resulted in extensive population growths and human activities. However, whether major human expansions started after Neolithic Time still remained controversial. With the benefit of 1000 Genome Project, we were able to analyze a total of 910 samples from 11 populations in Africa, Europe and Americas. From ...

journal_title：Scientific reports

authors： Zheng HX,Yan S,Qin ZD,Jin L

更新日期：2012-01-01 00:00:00

abstract：:The pristine lignin molecules contain multiple reactive hydroxyl [OH] groups, some of which undergo limited polymerization depending on their configuration (aromatic or aliphatic) or conformation. The key issue in lignin-polymerization is to quantify the number of hydroxyl groups in the pristine molecules for subseque...

journal_title：Scientific reports

authors： Park IK,Sun H,Kim SH,Kim Y,Kim GE,Lee Y,Kim T,Choi HR,Suhr J,Nam JD

更新日期：2019-05-07 00:00:00

abstract：:Recent advances in the field of Tissue Engineering allowed to control the three-dimensional organization of engineered constructs. Cell pattern imaging and in vivo follow-up remain a major hurdle in in situ bioprinting onto deep tissues. Magnetic Resonance Imaging (MRI) associated with Micron-sized superParamagnetic I...

journal_title：Scientific reports

authors： Kérourédan O,Ribot EJ,Fricain JC,Devillard R,Miraux S

更新日期：2018-10-25 00:00:00

abstract：:Information spreading in complex networks is often modeled as diffusing information with certain probability from nodes that possess it to their neighbors that do not. Information cascades are triggered when the activation of a set of initial nodes - seeds - results in diffusion to large number of nodes. Here, several...

journal_title：Scientific reports

authors： Jankowski J,Bródka P,Kazienko P,Szymanski BK,Michalski R,Kajdanowicz T

更新日期：2017-04-18 00:00:00

abstract：:The finite-difference time-domain (FDTD) method was employed to simulate the electric field distribution for noble metal (Au or Ag)/semiconductor (Ge or Si) substrates. The simulation showed that noble metal/Ge had stronger SERS enhancement than noble metal/Si, which was mainly attributed to the different dielectric c...

journal_title：Scientific reports

authors： Wang T,Zhang Z,Liao F,Cai Q,Li Y,Lee ST,Shao M

更新日期：2014-02-11 00:00:00

abstract：:Rodent species like Myodes glareolus and Microtus spp. are natural reservoirs for many zoonotic pathogens causing human diseases and are gaining increasing interest in the field of eco-immunology as candidate animal models. Despite their importance the lack of immunological reagents has hampered research in these anim...

journal_title：Scientific reports

authors： Torelli F,Zander S,Ellerbrok H,Kochs G,Ulrich RG,Klotz C,Seeber F

更新日期：2018-02-12 00:00:00

abstract：:The Japanese macaque (Macaca fuscata) exhibits a species-specific communication sound called the "coo call" to locate group members and maintain within-group contact. Monkeys have been demonstrated to be capable of discriminating between individuals based only on their voices, but there is still debate regarding how t...

journal_title：Scientific reports

authors： Furuyama T,Kobayasi KI,Riquimaroux H

更新日期：2016-08-23 00:00:00

abstract：:Functional brain connectivity is altered during the pathological processes of Alzheimer's disease (AD), but the specific evolutional rules are insufficiently understood. Resting-state functional magnetic resonance imaging indicates that the functional brain networks of individuals with AD tend to be disrupted in hub-l...

journal_title：Scientific reports

authors： Li W,Wang M,Zhu W,Qin Y,Huang Y,Chen X

更新日期：2016-09-28 00:00:00

abstract：:Climate change vulnerability assessment (CCVA) has become a mainstay conservation decision support tool. CCVAs are recommended to incorporate three elements of vulnerability - exposure, sensitivity and adaptive capacity - yet, lack of data frequently leads to the latter being excluded. Further, weighted or unweighted ...

journal_title：Scientific reports

authors： Ofori BY,Stow AJ,Baumgartner JB,Beaumont LJ

更新日期：2017-10-11 00:00:00

abstract：:AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex ligand, C8, to HeLa can...

journal_title：Scientific reports

authors： Carvalho J,Paiva A,Cabral Campello MP,Paulo A,Mergny JL,Salgado GF,Queiroz JA,Cruz C

更新日期：2019-05-28 00:00:00

abstract：:Recently, the first-order synchronization transition has been studied in systems of coupled phase oscillators. In this paper, we propose a framework to investigate the synchronization in the frequency-weighted Kuramoto model with all-to-all couplings. A rigorous mean-field analysis is implemented to predict the possib...

journal_title：Scientific reports

authors： Xu C,Sun Y,Gao J,Qiu T,Zheng Z,Guan S

更新日期：2016-02-23 00:00:00

abstract：:At the Ediacaran/Cambrian boundary, ecosystems witnessed an unparalleled biological innovation: the appearance of shelled animals. Here, we report new paleoecological and paleobiological data on Cloudina, which was one of the most abundant shelled animals at the end of the Ediacaran. We report the close association of...

journal_title：Scientific reports

authors： Becker-Kerber B,Pacheco MLAF,Rudnitzki ID,Galante D,Rodrigues F,Leme JM

更新日期：2017-07-14 00:00:00

abstract：:Difficulties in the production of lignin from rice straw because of high silica content in the recovered lignin reduce its recovery yield and applications as bio-fuel and aromatic chemicals. Therefore, the objective of this study is to develop a novel method to reduce the silica content in lignin from rice straw more ...

journal_title：Scientific reports

authors： Do NH,Pham HH,Le TM,Lauwaert J,Diels L,Verberckmoes A,Do NHN,Tran VT,Le PK

更新日期：2020-12-04 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:NOTCH plays a pivotal role during normal development and in congenital disorders and cancer. γ-secretase inhibitors are commonly used to probe NOTCH function, but also block processing of numerous other proteins. We discovered a new class of small molecule inhibitor that disrupts the interaction between NOTCH and RBPJ...

journal_title：Scientific reports

authors： Hurtado C,Safarova A,Smith M,Chung R,Bruyneel AAN,Gomez-Galeno J,Oswald F,Larson CJ,Cashman JR,Ruiz-Lozano P,Janiak P,Suzuki T,Mercola M

更新日期：2019-07-25 00:00:00

abstract：:The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We exposed an organotypi...

journal_title：Scientific reports

authors： Morgan MM,Livingston MK,Warrick JW,Stanek EM,Alarid ET,Beebe DJ,Johnson BP

更新日期：2018-05-08 00:00:00

abstract：:The aperture stop of the iris is subject to refraction by the cornea, and thus an outside observer sees a virtual image: the "entrance pupil" of the eye. When viewed off-axis, the entrance pupil has an elliptical form. The precise appearance of the entrance pupil is a consequence of the anatomical and optical properti...

journal_title：Scientific reports

authors： Aguirre GK

更新日期：2019-06-27 00:00:00

abstract：:We have previously reported that the sodium potassium adenosine triphosphatase (Na/K-ATPase) can effect the amplification of reactive oxygen species. In this study, we examined whether attenuation of oxidant stress by antagonism of Na/K-ATPase oxidant amplification might ameliorate experimental uremic cardiomyopathy i...

journal_title：Scientific reports

authors： Liu J,Tian J,Chaudhry M,Maxwell K,Yan Y,Wang X,Shah PT,Khawaja AA,Martin R,Robinette TJ,El-Hamdani A,Dodrill MW,Sodhi K,Drummond CA,Haller ST,Kennedy DJ,Abraham NG,Xie Z,Shapiro JI

更新日期：2016-10-04 00:00:00

abstract：:Coxsackievirus B3 (CVB3) is an important human pathogen associated with the development of acute pancreatitis, myocarditis, and type 1 diabetes. Currently, no vaccines or antiviral therapeutics are approved for the prevention and treatment of CVB3 infection. We found that Saururus chinensis Baill extract showed critic...

journal_title：Scientific reports

authors： Song JH,Ahn JH,Kim SR,Cho S,Hong EH,Kwon BE,Kim DE,Choi M,Choi HJ,Cha Y,Chang SY,Ko HJ

更新日期：2019-06-28 00:00:00

abstract：:MicroRNAs (MiRNAs) have been found to be dysregulated in lung cancer tissues compared to their matched paracancerous tissues. However, the roles of miRNAs in peripheral blood as potential biomarkers for early diagnosis of lung cancer remain poorly understood. Here we found that miR-33a-5p and miR-128-3p were down-regu...

journal_title：Scientific reports

authors： Pan J,Zhou C,Zhao X,He J,Tian H,Shen W,Han Y,Chen J,Fang S,Meng X,Jin X,Gong Z

更新日期：2018-11-12 00:00:00

abstract：:Two new indolizidine alkaloids crepidatumines A (1) and B (2) together with the stereoisomer of dendrocrepidine B (3) and known analog dendrocrepine (4) were isolated from D. crepidatum. Their structures were determined by HR-ESI-MS, NMR, and Electronic Circular Dichroism (ECD) experiments together with comparison of ...

journal_title：Scientific reports

authors： Xu X,Chen X,Yang R,Li Z,Zhou H,Bai Y,Yu M,Li B,Ding G

更新日期：2020-06-12 00:00:00

abstract：:The endo-levanase BT1760 of a human gut commensal Bacteroides thetaiotaomicron randomly cuts a β-2,6-linked fructan, levan, into fructo-oligosaccharides providing a prebiotic substrate for gut microbiota. Here we introduce the crystal structure of BT1760 at resolution of 1.65 Å. The fold of the enzyme is typical for G...

journal_title：Scientific reports

authors： Ernits K,Eek P,Lukk T,Visnapuu T,Alamäe T

更新日期：2019-06-11 00:00:00

abstract：:The formation of proper sensory afferent connections during development is essential for brain function. Activity-based competition is believed to drive ocular dominance columns (ODC) in mammals and in experimentally-generated three-eyed frogs. ODC formation is thus a compromise of activity differences between two eye...

journal_title：Scientific reports

authors： Elliott KL,Houston DW,Fritzsch B

更新日期：2015-02-09 00:00:00

abstract：:A systematic chemomechanical network model for the molecular motor kinesin is presented in this report. The network model is based on the nucleotide-dependent binding affinity of the heads to an microtubule (MT) and the asymmetries and similarities between the chemical transitions caused by the intramolecular strain b...

journal_title：Scientific reports

authors： Sumi T

更新日期：2017-04-25 00:00:00

abstract：:The weak correlation between pain and structural changes in knee osteoarthritis is widely reported. In a previous within-person, knee-matched case-control study among Caucasians, the severity of radiographic osteoarthritis (ROA) was strongly associated with both the presence of frequent knee pain and pain severity. We...

journal_title：Scientific reports

authors： Wang K,Kim HA,Felson DT,Xu L,Kim DH,Nevitt MC,Yoshimura N,Kawaguchi H,Lin J,Kang X,Zhang Y

更新日期：2018-01-22 00:00:00

abstract：:The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a surrogate of bacterial load), MTB/RIF TB-specific and internal positive control (IPC)-specific C(T) values, and clinical characteristics in ...

journal_title：Scientific reports

authors： Theron G,Peter J,Calligaro G,Meldau R,Hanrahan C,Khalfey H,Matinyenya B,Muchinga T,Smith L,Pandie S,Lenders L,Patel V,Mayosi BM,Dheda K

更新日期：2014-07-11 00:00:00

abstract：:The spectral distribution of light emitted from a scanning tunnelling microscope junction not only bears its intrinsic plasmonic signature but is also imprinted with the characteristics of optical frequency fluc- tuations of the tunnel current. Experimental spectra from gold-gold tunnel junctions are presented that sh...

journal_title：Scientific reports

authors： Kalathingal V,Dawson P,Mitra J

更新日期：2017-06-14 00:00:00

abstract：:A relation exists between network proximity of molecular entities in interaction networks, functional similarity and association with diseases. The identification of network regions associated with biological functions and pathologies is a major goal in systems biology. We describe a network diffusion-based pipeline f...

journal_title：Scientific reports

authors： Bersanelli M,Mosca E,Remondini D,Castellani G,Milanesi L

更新日期：2016-10-12 00:00:00

abstract：:Nα-acetylation is a naturally occurring irreversible modification of N-termini of proteins catalyzed by Nα-acetyltransferases (NATs). Although present in all three domains of life, it is little understood in bacteria. The functional grouping of NATs into six types NatA - NatF, in eukaryotes is based on subunit require...

journal_title：Scientific reports

authors： Pathak D,Bhat AH,Sapehia V,Rai J,Rao A

更新日期：2016-06-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Hassan R,Tantawy M,Gouda NA,Elzayat MG,Gabra S,Nabih A,Diab AA,El-Hadidi M,Bakry U,Shoeb MR,Elanany M,Shalaby L,Sayed AA

更新日期：2020-04-29 00:00:00