Comparative analysis of HER2 copy number between plasma and tissue samples in gastric cancer using droplet digital PCR.

abstract：:Circular Dichroism data are often decomposed into their constituent spectra to quantify the secondary structure of peptides or proteins but the estimation of the secondary structure content fails when light scattering leads to spectral distortion. If peptide-induced liposome self-association occurs, subtracting contro...

journal_title：Scientific reports

authors： Vermeer LS,Marquette A,Schoup M,Fenard D,Galy A,Bechinger B

更新日期：2016-12-22 00:00:00

abstract：:Daily music experience involves synchronizing movements in time with a perceived periodic beat. It has been established for over a century that beat synchronization is less stable for the visual than for the auditory modality. This auditory advantage of beat synchronization gives rise to the hypotheses that the neural...

journal_title：Scientific reports

authors： Gan L,Huang Y,Zhou L,Qian C,Wu X

更新日期：2015-07-07 00:00:00

abstract：:Restenosis remains a significant problem after angioplasty of hemodialysis vascular access. Both experimental and clinical studies have shown a protective effect of antioxidants against post-angioplasty restenosis. A prospective, randomized, feasibility study was conducted to investigate the effect of ascorbic acid to...

journal_title：Scientific reports

authors： Yang CW,Wu CC,Luo CM,Chuang SY,Chen CH,Shen YF,Tarng DC

更新日期：2019-07-31 00:00:00

abstract：:One strategy to address new potential dangers is to generate defensive responses to stimuli that remind learned threats, a phenomenon called fear generalization. During a threatening experience, the brain encodes implicit and explicit memory traces. Nevertheless, there is a lack of studies comparing implicit and expli...

journal_title：Scientific reports

authors： Manassero E,Mana L,Concina G,Renna A,Sacchetti B

更新日期：2019-09-16 00:00:00

abstract：:Surface ocean bubble-bursting generates aerosols composed of microscopic salt-water droplets, enriched in marine organic matter. The organic fraction profoundly influences aerosols' properties, by scattering solar radiations and nucleating water particles. Still little is known on the biochemical and microbiological c...

journal_title：Scientific reports

authors： Rastelli E,Corinaldesi C,Dell'Anno A,Lo Martire M,Greco S,Cristina Facchini M,Rinaldi M,O'Dowd C,Ceburnis D,Danovaro R

更新日期：2017-09-13 00:00:00

abstract：:The relationship between the cuprate pseudogap (Δ(p)) and superconducting gap (Δ(s)) remains an unsolved mystery. Here, we present a temperature- and doping-dependent tunneling study of submicron Bi(2)Sr(2)CaCu(2)O(8+δ) intrinsic Josephson junctions, which provides a clear evidence that Δ(s) closes at a temperature T(...

journal_title：Scientific reports

authors： Ren JK,Zhu XB,Yu HF,Tian Y,Yang HF,Gu CZ,Wang NL,Ren YF,Zhao SP

更新日期：2012-01-01 00:00:00

abstract：:Soil zinc (Zn) plays a crucial role in plant growth, but excessive accumulation in the environment may lead to air, water and soil pollution. It is affected by various chemical, environmental and spatial factors. Therefore, it is important to identify the factors influencing Zn content in the landscape. The main motiv...

journal_title：Scientific reports

authors： Jiang Y,Gao WW,Zhao JL,Chen Q,Liang D,Xu C,Huang LS,Ruan LM

更新日期：2018-10-22 00:00:00

abstract：:Electrical power systems are one of the most important infrastructures that support our society. However, their vulnerabilities have raised great concern recently due to several large-scale blackouts around the world. In this paper, we investigate the robustness of power systems against cascading failures initiated by...

journal_title：Scientific reports

authors： Zhang Y,Yağan O

更新日期：2016-06-21 00:00:00

abstract：:Metformin is an antidiabetic drug which possesses antiproliferative activity in cancer cells when administered at high doses, due to its unfavorable pharmacokinetics. The aim of this work was to develop a pharmacological tool for the release of metformin in proximity of the tumor, allowing high local concentrations, a...

journal_title：Scientific reports

authors： Baldassari S,Solari A,Zuccari G,Drava G,Pastorino S,Fucile C,Marini V,Daga A,Pattarozzi A,Ratto A,Ferrari A,Mattioli F,Barbieri F,Caviglioli G,Florio T

更新日期：2018-03-02 00:00:00

abstract：:Meishan boars are known for their early sexual maturity. However, they exhibit a significantly smaller testicular size and a reduced proportion of Sertoli cells and daily sperm production compared with Duroc boars. The testes of Duroc and Meishan boars at 20, 75 and 270 days of age were used for histological and trans...

journal_title：Scientific reports

authors： Ding H,Luo Y,Liu M,Huang J,Xu D

更新日期：2016-02-11 00:00:00

abstract：:Diarrheagenic Escherichia coli (DEC) causes human diarrhea symptom in both healthy and immunocompromised individuals. An auto-microfluidic thin-film chip (AMTC) instrument integrating one-step multiplex PCR (mPCR) with reverse dot blot hybridization (RDBH) was developed for high-throughput detection of DEC. The novel ...

journal_title：Scientific reports

authors： Yun Z,Zeng L,Huang W,Wu Q,Fan Y,Zheng S,Peng L,Han J,Huang Y,Zhou H,Chen H

更新日期：2018-08-27 00:00:00

abstract：:Macroscopic rhythms are often signatures of healthy functioning in living organisms, but they are still poorly understood on their microscopic bases. Globally interacting oscillators with heterogeneous couplings are here considered. Thorough theoretical and numerical analyses indicate the presence of multiple phase tr...

journal_title：Scientific reports

authors： Qiu T,Bonamassa I,Boccaletti S,Liu Z,Guan S

更新日期：2018-08-28 00:00:00

abstract：:Glucagon is a pancreatic hormone and increases the blood glucose levels. It may be incorporated in a dual hormone artificial pancreas, a device to automatically and continuously control blood glucose levels of individuals with diabetes. Artificial pancreas systems have been developed for use in the subcutaneous tissue...

journal_title：Scientific reports

authors： Åm MK,Dirnena-Fusini I,Fougner AL,Carlsen SM,Christiansen SC

更新日期：2020-08-13 00:00:00

abstract：:Many mathematical models have been published with the purpose of explaining aspects of T-cell development in the thymus. In this manuscript we adapted a four-compartment model of the thymus and used a range of mathematical approaches with the aim of explaining the dynamics of the four main thymocyte populations in the...

journal_title：Scientific reports

authors： Zaharie D,Moleriu RD,Mic FA

更新日期：2016-11-08 00:00:00

abstract：:CD96 is a promising candidate for immunotherapy. However, its role and importance in glioma remains unknown. We thus aimed to genetically and clinically characterize CD96 expression in gliomas. For this, we extracted RNA-seq data of 699 glioma samples from the TCGA dataset and validated these findings using the CGGA d...

journal_title：Scientific reports

authors： Liu F,Huang J,He F,Ma X,Fan F,Meng M,Zhuo Y,Zhang L

更新日期：2020-07-01 00:00:00

abstract：:There are large health, societal, and economic costs associated with attrition from psychological services. The recently emerged, innovative statistical tool of complex network analysis was used in the present proof-of-concept study to improve the prediction of attrition. Fifty-eight patients undergoing psychological ...

journal_title：Scientific reports

authors： Lutz W,Schwartz B,Hofmann SG,Fisher AJ,Husen K,Rubel JA

更新日期：2018-05-18 00:00:00

abstract：:GDP-mannose pyrophosphorylase (GMP) catalyzed the formation of GDP-mannose, which serves as a donor for the biosynthesis of mannose-containing polysaccharides. In this study, three GMP genes from Dendrobium officinale (i.e., DoGMPs) were cloned and analyzed. The putative 1000 bp upstream regulatory region of these DoG...

journal_title：Scientific reports

authors： He C,Yu Z,Teixeira da Silva JA,Zhang J,Liu X,Wang X,Zhang X,Zeng S,Wu K,Tan J,Ma G,Luo J,Duan J

更新日期：2017-02-08 00:00:00

abstract：:As an emerging sterilization technology, cold atmospheric plasma offers a dry, non-thermal, rapid process that is minimally damaging to a majority of substrates. However, the mechanisms by which plasma interacts with living cells are poorly understood and the plasma generation apparatuses are complex and resource-inte...

journal_title：Scientific reports

authors： Pai K,Timmons C,Roehm KD,Ngo A,Narayanan SS,Ramachandran A,Jacob JD,Ma LM,Madihally SV

更新日期：2018-11-12 00:00:00

abstract：:The charge transfer from the main catalyst to the cocatalyst is a key factor to enhance catalytic activity for photocatalytic nanocomposite materials. In order to enhance the charge transfer between Bi2WO6 and graphene, we inlet MoS2 as a "stepping-stone" into Bi2WO6 and graphene. Here, we report an effective strategy...

journal_title：Scientific reports

authors： Liu M,Xue X,Yu S,Wang X,Hu X,Tian H,Chen H,Zheng W

更新日期：2017-06-16 00:00:00

abstract：:In the highly interconnected architectures of the cerebral cortex, recurrent intracortical loops disproportionately outnumber thalamo-cortical inputs. These networks are also capable of generating neuronal activity without feedforward sensory drive. It is unknown, however, what spatiotemporal patterns may be solely at...

journal_title：Scientific reports

authors： Kodama NX,Feng T,Ullett JJ,Chiel HJ,Sivakumar SS,Galán RF

更新日期：2018-01-12 00:00:00

abstract：:The emergence of metallic conduction in layered dichalcogenide semiconductor materials by chemical doping is one of key issues for two-dimensional (2D) materials engineering. At present, doping methods for layered dichalcogenide materials have been limited to an ion intercalation between layer units or electrostatic c...

journal_title：Scientific reports

authors： Kim SI,Hwang S,Kim SY,Lee WJ,Jung DW,Moon KS,Park HJ,Cho YJ,Cho YH,Kim JH,Yun DJ,Lee KH,Han IT,Lee K,Sohn Y

更新日期：2016-01-21 00:00:00

abstract：:Psychiatric disorders have been widely reported to be associated with systemic inflammation upregulation and adiposity. However, there are no data that link adipose tissue inflammation to these mental disorders. The analysis of adipokines and inflammation-related markers in adipose tissue could help to elucidate the p...

journal_title：Scientific reports

authors： Coín-Aragüez L,Pavón FJ,Contreras A,Gentile AM,Lhamyani S,De Diego-Otero Y,Casado Y,Oliva Olivera W,Olveira G,Tinahones FJ,Pérez Costillas L,El Bekay R

更新日期：2018-11-30 00:00:00

abstract：:Memristive systems have gained considerable attention in the field of neuromorphic engineering, because they allow the emulation of synaptic functionality in solid state nano-physical systems. In this study, we show that memristive behavior provides a broad working framework for the phenomenological modelling of cellu...

journal_title：Scientific reports

authors： Diederich N,Bartsch T,Kohlstedt H,Ziegler M

更新日期：2018-06-19 00:00:00

abstract：:Macro- and micro-environmental factors modulate parasite loads in fish, determining parasitic abundances, diversity, and interaction dynamics. In this study, seasonal variations in larval ectoparasites on fish larvae in the northern Humboldt Current System (HCS) were evaluated using a delta-gamma generalized linear mo...

journal_title：Scientific reports

authors： Paredes LD,Landaeta MF,Molinet C,González MT

更新日期：2021-01-12 00:00:00

abstract：:We show a hybrid structure consisting of Si film with photonic crystal surface and random triangular gold grooves reflector at the bottom, which is capable of realizing efficient, broad-band, wide-angle optical absorption. It is numerically demonstrated that the enhanced absorption in a broad wavelength range (0.3-9.9...

journal_title：Scientific reports

authors： Chen ZH,Qiao N,Yang Y,Ye H,Liu S,Wang W,Wang Y

更新日期：2015-08-04 00:00:00

abstract：:The familial forms of early onset pre-eclampsia and related syndromes (HELLP) present with hypertension and proteinuria in the mother and growth restriction of the fetus. Genetically, these clinically similar entities are caused by different founder-dependent, placentally-expressed paralogous genes. All susceptibility...

journal_title：Scientific reports

authors： Oudejans CB,Poutsma A,Michel OJ,Thulluru HK,Mulders J,van de Vrugt HJ,Sistermans EA,van Dijk M

更新日期：2016-08-24 00:00:00

abstract：:Negative hemodynamic response has been widely reported in blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging studies, however its origin is still controversial. Optical intrinsic signal (OIS) imaging can be used to study brain activity by simultaneously recording hemodynamic signals at diff...

journal_title：Scientific reports

authors： Ma Z,Cao P,Sun P,Zhao L,Li L,Tong S,Lu Y,Yan Y,Chen Y,Chai X

更新日期：2016-02-10 00:00:00

abstract：:We used Mendelian randomization to estimate the causal effects of the liver enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT), on diabetes and cardiovascular disease, using genetic variants predicting these liver enzymes at genome wide significance applied to exten...

journal_title：Scientific reports

authors： Liu J,Au Yeung SL,Lin SL,Leung GM,Schooling CM

更新日期：2016-12-20 00:00:00

abstract：:Molecular tests hold great potential for tuberculosis (TB) diagnosis, but are costly, time consuming, and HIV-infected patients are often sputum scarce. Therefore, alternative approaches are needed. We evaluated automated digital chest radiography (ACR) as a rapid and cheap pre-screen test prior to Xpert MTB/RIF (Xper...

journal_title：Scientific reports

authors： Philipsen RH,Sánchez CI,Maduskar P,Melendez J,Peters-Bax L,Peter JG,Dawson R,Theron G,Dheda K,van Ginneken B

更新日期：2015-07-27 00:00:00

abstract：:The biochemical abnormalities and oxidative stress during pathogenesis of hepatic fibrosis could lead to alteration of trace elements. We studied the alteration of major trace elements during the pathogenesis of N-nitrosodimethylamine (NDMA)-induced hepatic fibrosis in rats. The biochemical and pathological indices of...

journal_title：Scientific reports

authors： George J,Tsutsumi M,Tsuchishima M

更新日期：2019-01-24 00:00:00