Pseudomonas aeruginosa OprF plays a role in resistance to macrophage clearance during acute infection.

abstract：:Active immunotherapy targeting β-amyloid (Aβ) is the most promising strategy to prevent or treat Alzheimer's disease (AD). Based on pre-clinical studies and clinical trials, a safe and effective AD vaccine requires a delicate balance between providing therapeutically adequate anti-Aβ antibodies and eliminating or supp...

journal_title：Scientific reports

authors： Liu S,Shi D,Wang HC,Yu YZ,Xu Q,Sun ZW

更新日期：2015-01-14 00:00:00

abstract：:To explore the association between methylation of antisense non-coding RNA in the INK4 locus (ANRIL) and coronary artery disease (CAD) development. Methylation levels of ANRIL in 100 subjects with CAD and 100 controls were quantitatively analyzed using Sequenom MassARRAY. Kyoto Encyclopedia of Genes and Genomes (KEGG)...

journal_title：Scientific reports

authors： Zhao CH,Cao HT,Zhang J,Jia QW,An FH,Chen ZH,Li LH,Wang LS,Ma WZ,Yang ZJ,Jia EZ

更新日期：2019-10-25 00:00:00

abstract：:Numerous essential metal elements (EMEs) are necessary to maintain the proper function of human body. In this case-control study, we investigated the associations of 11 EMEs [Calcium (Ca), potassium (K), magnesium (Mg), sodium (Na), manganese (Mn), selenium (Se), cobalt (Co), Molybdenum (Mo), copper (Cu), zinc (Zn), a...

journal_title：Scientific reports

authors： Ma J,Yan L,Guo T,Yang S,Liu Y,Xie Q,Ni D,Wang J

更新日期：2020-07-03 00:00:00

abstract：:Early diagnosis of dementia including Alzheimer's disease (AD) is an urgent medical and welfare issue. However, to date, no simple biometrics have been available. We reported that blood DNA methylation levels of the COASY gene, which encodes coenzyme A synthase, were increased in individuals with AD and amnestic mild ...

journal_title：Scientific reports

authors： Kobayashi N,Shinagawa S,Niimura H,Kida H,Nagata T,Tagai K,Shimada K,Oka N,Shikimoto R,Noda Y,Nakajima S,Mimura M,Shigeta M,Kondo K

更新日期：2020-07-22 00:00:00

abstract：:Laser heating of gold nanospheres (GNS) is increasingly prevalent in biomedical applications due to tunable optical properties that determine heating efficiency. Although many geometric parameters (i.e. size, morphology) can affect optical properties of individual GNS and their heating, no specific studies of how GNS ...

journal_title：Scientific reports

authors： Wang Y,Gao Z,Han Z,Liu Y,Yang H,Akkin T,Hogan CJ,Bischof JC

更新日期：2021-01-13 00:00:00

abstract：:State of charge (SOC) is a crucial index used in the assessment of electric vehicle (EV) battery storage systems. Thus, SOC estimation of lithium-ion batteries has been widely investigated because of their fast charging, long-life cycle, and high energy density characteristics. However, precise SOC assessment of lithi...

journal_title：Scientific reports

authors： Hannan MA,Lipu MSH,Hussain A,Ker PJ,Mahlia TMI,Mansor M,Ayob A,Saad MH,Dong ZY

更新日期：2020-03-13 00:00:00

abstract：:High-altitude-adapted ectotherms can escape competition from dominant species by tolerating low temperatures at cooler elevations, but climate change is eroding such advantages. Studies evaluating broad-scale impacts of global change for high-altitude organisms often overlook the mitigating role of biotic factors. Yet...

journal_title：Scientific reports

authors： Muluvhahothe MM,Joseph GS,Seymour CL,Munyai TC,Foord SH

更新日期：2021-01-08 00:00:00

abstract：:A larger amount of sequence data in private and public databases produced by next-generation sequencing put new challenges due to limitation associated with the alignment-based method for sequence comparison. So, there is a high need for faster sequence analysis algorithms. In this study, we developed an alignment-fre...

journal_title：Scientific reports

authors： Saw AK,Raj G,Das M,Talukdar NC,Tripathy BC,Nandi S

更新日期：2019-03-06 00:00:00

abstract：:Inhomogeneity in the ground state is an intriguing, emergent phenomenon in magnetism. Recently, it has been observed in the magnetostructural channel of the geometrically frustrated α-NaMnO2, for the first time in the absence of active charge degrees of freedom. Here we report an in-depth numerical and local-probe exp...

journal_title：Scientific reports

authors： Zorko A,Kokalj J,Komelj M,Adamopoulos O,Luetkens H,Arčon D,Lappas A

更新日期：2015-03-19 00:00:00

abstract：:Herbicides are the most commonly used means of controlling weeds. Recently, there has been growing concern over the potential impacts of global climate change, specifically, increasing temperatures and elevated carbon dioxide (CO2) concentrations, on the sensitivity of weeds to herbicides. Here, glyphosate response of...

journal_title：Scientific reports

authors： Matzrafi M,Brunharo C,Tehranchian P,Hanson BD,Jasieniuk M

更新日期：2019-02-18 00:00:00

abstract：:In general, the poultry industry uses 0.5-1 ppm chlorine solution in the meat sanitization process. However, chlorine can react with organic material and produce halogenated organic compounds, notably chloroform, which causes bladder and rectal cancer in humans. For this reason, many industries try to avoid chlorine. ...

journal_title：Scientific reports

authors： Royintarat T,Choi EH,Boonyawan D,Seesuriyachan P,Wattanutchariya W

更新日期：2020-01-31 00:00:00

abstract：:We explore the effect of temperature on the interaction of polydisperse mixtures of nonionic poly(ethylene glycol) (PEG) polymers of different average molar masses with the biological nanopore α-hemolysin. In contrast with what has been previously observed with various nanopores and analytes, we find that, for PEGs la...

journal_title：Scientific reports

authors： Piguet F,Ouldali H,Discala F,Breton MF,Behrends JC,Pelta J,Oukhaled A

更新日期：2016-12-07 00:00:00

abstract：:HSV-2 is one of the most common sexually transmitted pathogens worldwide and HSV-2 infection triggers cytokine and chemokine production. However, little is known about which HSV-2 genes engage in the regulation of NF-κB signaling and what mechanisms are involved. In a screen of the unique short (Us) regions of HSV-2, ...

journal_title：Scientific reports

authors： Lu X,Huang C,Zhang Y,Lin Y,Wang X,Li Q,Liu S,Tang J,Zhou L

更新日期：2017-08-21 00:00:00

abstract：:Population structure and biogeography of marine organisms are formed by different drivers than in terrestrial organisms. Yet, very little information is available even for common marine organisms and even less for their associated parasites. Here we report the first analysis of population structure of both a cephalopo...

journal_title：Scientific reports

authors： Drábková M,Jachníková N,Tyml T,Sehadová H,Ditrich O,Myšková E,Hypša V,Štefka J

更新日期：2019-10-04 00:00:00

abstract：:We aimed to model longitudinal data to create predictive growth charts for weight in preterm infants from birth till discharge, that took into account the differing growth rates post-birth when compared to in-utero growth and therefore was more representative of the data than the UK1990 reference charts. Data from bir...

journal_title：Scientific reports

authors： Watkins WJ,Farewell D,Banerjee S,Nasef H,James A,Chakraborty M

更新日期：2020-03-04 00:00:00

abstract：:There is a growing need for biolabels that can be used in both optical and electron microscopies, are non-cytotoxic, and do not photobleach. Such biolabels could enable targeted nanoscale imaging of sub-cellular structures, and help to establish correlations between conjugation-delivered biomolecules and function. Her...

journal_title：Scientific reports

authors： Zurbuchen MA,Lake MP,Kohan SA,Leung B,Bouchard LS

更新日期：2013-01-01 00:00:00

abstract：:Telomeres play an important role in maintaining chromosomal integrity. With each cell division, telomeres are shortened and leukocyte telomere length (LTL) has therefore been considered a marker for biological age. LTL is associated with various lifetime stressors and health-related outcomes. Transgenerational effects...

journal_title：Scientific reports

authors： Ämmälä AJ,Vitikainen EIK,Hovatta I,Paavonen J,Saarenpää-Heikkilä O,Kylliäinen A,Pölkki P,Porkka-Heiskanen T,Paunio T

更新日期：2020-08-19 00:00:00

abstract：:A new and facile approach to selectively functionalize the internal and external surfaces of porous silicon (pSi) for drug delivery applications is reported. To provide a surface that is suitable for sustained drug release of the hydrophobic cancer chemotherapy drug camptothecin (CPT), the internal surfaces of pSi fil...

journal_title：Scientific reports

authors： Zhang DX,Yoshikawa C,Welch NG,Pasic P,Thissen H,Voelcker NH

更新日期：2019-02-04 00:00:00

abstract：:We demonstrate a novel route to achieving highly efficient and strongly confined spoof surface plasmon polaritons (SPPs) waveguides at subwavelength scale enabled by planar staggered plasmonic waveguides (PSPWs). The structure of these new waveguides consists of an ultrathin metallic strip with periodic subwavelength ...

journal_title：Scientific reports

authors： Ye L,Xiao Y,Liu Y,Zhang L,Cai G,Liu QH

更新日期：2016-12-05 00:00:00

abstract：:Smoking aggravates HIV-1 pathogenesis and leads to decreased responses to antiretroviral therapy. In this study, we aim to find a molecular mechanism that would explain smoking-induced HIV-1 replication. Benzo(a)pyrene (BaP), a major carcinogen in cigarette, requires metabolic activation through cytochrome P450s (CYPs...

journal_title：Scientific reports

authors： Ranjit S,Sinha N,Kodidela S,Kumar S

更新日期：2018-07-10 00:00:00

abstract：:In this paper, we investigate the magnetic behavior of a single-walled hexagonal spin-1 Ising nanotube by using the effective field theory (EFT) with correlations and the differential operator technique (DOT). The system consists of six long legs distributed parallel to each other on a hexagonal basis. Within each cha...

journal_title：Scientific reports

authors： ElMaddahi Z,El Hafidi MY,El Hafidi M

更新日期：2019-08-26 00:00:00

abstract：:Recent reports on direct reprogramming of cancer cells (iPCs) which results in reduced tumorigenic potential has attributed the importance of epigenetics in tumorigenesis, but lacked genome-wide analysis. Here we describe successful generation of iPCs from non-small cell lung cancer (NSCLC) cell lines. Following repro...

journal_title：Scientific reports

authors： Mahalingam D,Kong CM,Lai J,Tay LL,Yang H,Wang X

更新日期：2012-01-01 00:00:00

abstract：:The formation of proper sensory afferent connections during development is essential for brain function. Activity-based competition is believed to drive ocular dominance columns (ODC) in mammals and in experimentally-generated three-eyed frogs. ODC formation is thus a compromise of activity differences between two eye...

journal_title：Scientific reports

authors： Elliott KL,Houston DW,Fritzsch B

更新日期：2015-02-09 00:00:00

abstract：:Vitamin D may reduce mortality from prostate cancer (PC). We examined the associations of post-treatment plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations with PC mortality. Participants were PC cases from the New South Wales Prostate Cancer Care. All contactable and consenting participants, at 4.9...

journal_title：Scientific reports

authors： Nair-Shalliker V,Bang A,Egger S,Clements M,Gardiner RA,Kricker A,Seibel MJ,Chambers SK,Kimlin MG,Armstrong BK,Smith DP

更新日期：2020-05-08 00:00:00

abstract：:Interleukin-27 (IL-27) is an important cytokine in inflammatory diseases, including coronary artery disease (CAD). To explore the precise role of IL-27 in CAD, we investigated the genetic association between IL27 and CAD in the GeneID Chinese Han population. A two-stage case control association analysis was performed ...

journal_title：Scientific reports

authors： Fan Q,Nie S,Li S,Liao Y,Zhang H,Zha L,Wang F,Tang T,Xia N,Xu C,Wang P,Xie T,Xie J,Lu Q,Li Q,Qian J,Li B,Wu G,Wu Y,Yang Y,Wang QK,Tu X,Cheng X

更新日期：2016-05-12 00:00:00

abstract：:Due to the substantial limitation of study population, Spindle cell sarcoma (SCS) was unexplored comprehensively. In this study, we investigated the clinical characteristics and disease specific prognostic factors of SCS. 3299 SCS cases were identified and extracted from Surveillance, Epidemiology, and End Results (SE...

journal_title：Scientific reports

authors： Feng L,Wang M,Yibulayin F,Zhang H,Yang YL,Ren F,Wushou A

更新日期：2018-03-22 00:00:00

abstract：:Lung fibrosis is an unabated wound healing response characterized by the loss and aberrant function of lung epithelial cells. Herein, we report that extracellular Clusterin promoted epithelial cell apoptosis whereas intracellular Clusterin maintained epithelium viability during lung repair. Unlike normal and COPD lung...

journal_title：Scientific reports

authors： Habiel DM,Camelo A,Espindola M,Burwell T,Hanna R,Miranda E,Carruthers A,Bell M,Coelho AL,Liu H,Pilataxi F,Clarke L,Grant E,Lewis A,Moore B,Knight DA,Hogaboam CM,Murray LA

更新日期：2017-11-13 00:00:00

abstract：:Tilapias (family Cichlidae) are of importance in aquaculture and fisheries. Hybridisation and introgression are common within tilapia genera but are difficult to analyse due to limited numbers of species-specific genetic markers. We tested the potential of double digested restriction-site associated DNA (ddRAD) sequen...

journal_title：Scientific reports

authors： Syaifudin M,Bekaert M,Taggart JB,Bartie KL,Wehner S,Palaiokostas C,Khan MGQ,Selly SC,Hulata G,D'Cotta H,Baroiller JF,McAndrew BJ,Penman DJ

更新日期：2019-09-10 00:00:00

abstract：:The immunomodulatory properties of human endometrial mesenchymal stem cells (eMSC) have not been well characterised. Initial studies showed that eMSC modulated the chronic inflammatory response to a non-degradable polyamide/gelatin mesh in a xenogeneic rat skin wound repair model, but the mechanism remains unclear. In...

journal_title：Scientific reports

authors： Darzi S,Deane JA,Nold CA,Edwards SE,Gough DJ,Mukherjee S,Gurung S,Tan KS,Vashi AV,Werkmeister JA,Gargett CE

更新日期：2018-04-26 00:00:00

abstract：:Deprivation of maternal care during early development markedly affects emotional development, but the underlying neuromolecular mechanisms are not fully understood. In a mouse model of disrupted mother-infant relationship, early weaning causes long-term impacts on pups to exhibit increased corticosterone secretion, an...

journal_title：Scientific reports

authors： Kikusui T,Kanbara N,Ozaki M,Hirayama N,Ida K,Tokita M,Tanabe N,Mitsuyama K,Abe H,Yoshida M,Nagasawa M,Mogi K

更新日期：2019-03-08 00:00:00