Abstract：
:Due to the substantial limitation of study population, Spindle cell sarcoma (SCS) was unexplored comprehensively. In this study, we investigated the clinical characteristics and disease specific prognostic factors of SCS. 3299 SCS cases were identified and extracted from Surveillance, Epidemiology, and End Results (SEER) database (1973-2017). White people account for 79.1% with median age of 57 years without predominance in any gender. Significant disease specific survival (DSS) and overall survival (OS) were found differentiated in age, T stage, N stage, M stage, AJCC stage, SEER historic stage, tumor locations, surgery, and pathologic grade. In the multivariate Cox analysis, the age >64 years (for DSS, P < 0.001 and for OS, P < 0.001; Reference age ≤64 years), AJCC stage III (for DSS, P = 0.006 and for OS, P = 0.04; Reference: AJCC stage I), and non-surgical treatment (for DSS, P < 0.001 and for OS, P < 0.001; Reference: surgery) were independently associated with worse DSS and OS. In brief, our study demonstrated that SCS mostly found in white people at fifth to seventh decades of life without gender predilection. The patient's age, AJCC stage, tumor location and surgery were independent prognostic indicators for both DSS and OS of SCS.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Feng L,Wang M,Yibulayin F,Zhang H,Yang YL,Ren F,Wushou Adoi
10.1038/s41598-018-23145-4subject
Has Abstractpub_date
2018-03-22 00:00:00pages
5024issue
1issn
2045-2322pii
10.1038/s41598-018-23145-4journal_volume
8pub_type
杂志文章abstract：:The role of the different lymphocyte populations in liver microenvironment of chronic hepatitis C (CHC) patients is still matter of debate. Since Th17 and Treg have opposite functions, their balance could affect disease progression. The aim was to explore liver microenvironment and its peripheral blood counterpart in ...
journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2017-01-04 00:00:00
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pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2017-03-27 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Scientific reports
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journal_title：Scientific reports
pub_type： 杂志文章
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journal_title：Scientific reports
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journal_title：Scientific reports
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2016-12-05 00:00:00
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journal_title：Scientific reports
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pub_type： 杂志文章
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更新日期：2016-09-29 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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