Undiluted Serum Eye Drops for the Treatment of Persistent Corneal Epitheilal Defects.

abstract：:Chemical chaperones including arginine and its derivatives are widely used by biochemists working on the design of agents, which are able to efficiently suppress protein aggregation. To elucidate the mechanisms of anti-aggregation activity of chemical chaperones, methods based on registration of the increment in light...

journal_title：Scientific reports

authors： Borzova VA,Markossian KA,Kleymenov SY,Kurganov BI

更新日期：2017-06-21 00:00:00

abstract：:Uniaxial-stress experiments have been performed for the 3287- and 2445-cm-1 local vibrational modes assigned to the positive charge state of interstitial hydrogen [Formula: see text] and deuterium [Formula: see text], respectively, occurring in mono-crystalline rutile TiO2. The onset of the defect alignment under the ...

journal_title：Scientific reports

authors： Hupfer AJ,Monakhov EV,Svensson BG,Chaplygin I,Lavrov EV

更新日期：2017-12-06 00:00:00

abstract：:Most Group I Clostridium botulinum strains harbor botulinum neurotoxin (bont) genes on their chromosome, while some carry these genes (including bont/a, bont/b, and bont/f) on large plasmids. Prior work in our laboratory demonstrated that Group I BoNT plasmids were mobilized to C. botulinum recipient strains containin...

journal_title：Scientific reports

authors： Nawrocki EM,Bradshaw M,Johnson EA

更新日期：2018-02-15 00:00:00

abstract：:Designing a new generation of energy-intensive and sustainable electrode materials for batteries to power a variety of applications is an imperative task. The use of biomaterials as a nanosized structural template for these materials has the potential to produce hitherto unachievable structures. In this report, we hav...

journal_title：Scientific reports

authors： Beznosov SN,Veluri PS,Pyatibratov MG,Chatterjee A,MacFarlane DR,Fedorov OV,Mitra S

更新日期：2015-01-13 00:00:00

abstract：:Recently, based on space-variant Pancharatnam-Berry (PB) phases, various flat devices allowing abrupt changes of beam parameters have been predicted and demonstrated to implement intriguing manipulation on spin states in three dimensions, including the efficient generation of vector beams, spin Hall effect of light an...

journal_title：Scientific reports

authors： Li P,Guo X,Qi S,Han L,Zhang Y,Liu S,Li Y,Zhao J

更新日期：2018-06-29 00:00:00

abstract：:Leaching of nitrate from fertilisers diminishes nitrogen use efficiency (the portion of nitrogen used by a plant) and is a major source of agricultural pollution. To improve nitrogen capture, grasses such as brachiaria are increasingly used, especially in South America and Africa, as a cover crop, either via intercrop...

journal_title：Scientific reports

authors： Galdos MV,Brown E,Rosolem CA,Pires LF,Hallett PD,Mooney SJ

更新日期：2020-03-19 00:00:00

abstract：:Sterility mosaic disease (SMD) is one of the serious production constraints that may lead to complete yield loss in pigeonpea. Three mapping populations including two recombinant inbred lines and one F2, were used for phenotyping for SMD resistance at two locations in three different years. Genotyping-by-sequencing ap...

journal_title：Scientific reports

authors： Saxena RK,Kale SM,Kumar V,Parupali S,Joshi S,Singh V,Garg V,Das RR,Sharma M,Yamini KN,Ghanta A,Rathore A,Sameerkumar CV,Saxena KB,Varshney RK

更新日期：2017-05-12 00:00:00

abstract：:We propose efficient schemes of direct concurrence measurement for two-qubit spin and photon-polarization entangled states via the interaction between single-photon pulses and nitrogen-vacancy (NV) centers in diamond embedded in optical microcavities. For different entangled-state types, diversified quantum devices an...

journal_title：Scientific reports

authors： Cheng LY,Yang GH,Guo Q,Wang HF,Zhang S

更新日期：2016-01-18 00:00:00

abstract：:Norfloxacin (NOF) is an environmentally harmful and ubiquitous aquatic pollutant with extensive production and application. In this study, a novel composition named carbon-based composite photocatalytic material of zinc oxide and zinc sulphide (ZnO/ZnS@BC) was successfully obtained by the impregnation-roasting method ...

journal_title：Scientific reports

authors： Liu W,He T,Wang Y,Ning G,Xu Z,Chen X,Hu X,Wu Y,Zhao Y

更新日期：2020-07-17 00:00:00

abstract：:The correlation between hepatitis B virus (HBV) infection and metabolic syndrome (MetS) remains to be clarified. In this study, we explored this association in a large population in Southwest China. This was a cross-sectional study, with pooled adult health data. Multivariate logistic regression analysis, controlling ...

journal_title：Scientific reports

authors： Yan LB,Liao J,Han N,Zhou LY,Wang XE,Wang YJ,Tang H

更新日期：2020-04-21 00:00:00

abstract：:Isoliquiritigenin (ISL), a natural flavonoid extracted from licorice, has been demonstrated to exert attenuation of osteoclastogenesis and anti-angiogenesis activity in a wide variety of cells. Here, we first evaluated the effects of ISL on pathogenesis of osteoarthritis in a mouse model of OA. The data showed that IS...

journal_title：Scientific reports

authors： Ji B,Zhang Z,Guo W,Ma H,Xu B,Mu W,Amat A,Cao L

更新日期：2018-01-29 00:00:00

abstract：:The interaction between two different materials can present novel phenomena that are quite different from the physical properties observed when each material stands alone. Strong electronic correlations, such as magnetism and superconductivity, can be produced as the result of enhanced Coulomb interactions between ele...

journal_title：Scientific reports

authors： Hwang C,Cybart SA,Shin SJ,Kim S,Kim K,Rappoport TG,Wu SM,Jozwiak C,Fedorov AV,Mo SK,Lee DH,Min BI,Haller EE,Dynes RC,Castro Neto AH,Lanzara A

更新日期：2016-02-18 00:00:00

abstract：:Luminance plays a modulating role in the processes of several visual tasks, which in turn provides significant information for the understanding of visual processing. Here, using a binocular phase combination paradigm, we studied the effect of unilateral changes in mean luminance on binocular combination in both norma...

journal_title：Scientific reports

authors： Zhou J,Jia W,Huang CB,Hess RF

更新日期：2013-01-01 00:00:00

abstract：:Sex-dependent effects of mismatched prenatal-postnatal maternal conditions are predicted by combining two evolutionary hypotheses: that foetal conditions provide a forecast of likely postnatal environments (Predictive Adaptive Response), and that the female foetus is better adapted than the male to maternal adversity ...

journal_title：Scientific reports

authors： Hill J,Pickles A,Wright N,Braithwaite E,Sharp H

更新日期：2019-02-21 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： de Genaro IS,de Almeida FM,Hizume-Kunzler DC,Moriya HT,Silva RA,Cruz JCG,Lopes RB,Righetti RF,de Paula Vieira R,Saiki M,Martins MA,Tibério IFLC,Arantes-Costa FM,Saraiva-Romanholo BM

更新日期：2018-12-12 00:00:00

abstract：:Increasingly, biofilms are being recognised for their causative role in persistent infections (like cystic fibrosis, otitis media, diabetic foot ulcers) and nosocomial diseases (biofilm-infected vascular catheters, implants and prosthetics). Given the clinical relevance of biofilms and their recalcitrance to conventio...

journal_title：Scientific reports

authors： Sharma A,Gupta P,Kumar R,Bhardwaj A

更新日期：2016-02-25 00:00:00

abstract：:Fibrin polymerization is a necessary part of hemostasis but clots can obstruct blood vessels and cause heart attacks and strokes. The polymerization reactions are specific and controlled, involving strong knob-into-hole interactions to convert soluble fibrinogen into insoluble fibrin. It has long been assumed that clo...

journal_title：Scientific reports

authors： Chernysh IN,Nagaswami C,Purohit PK,Weisel JW

更新日期：2012-01-01 00:00:00

abstract：:Invasive aspergillosis (IA) is a life-threatening complication among allogeneic hematopoietic stem cell transplant (alloSCT) recipients. Despite well known risk factors and different available assays, diagnosis of invasive aspergillosis remains challenging. 103 clinical variables from patients with hematological malig...

journal_title：Scientific reports

authors： Zoran T,Weber M,Springer J,White PL,Bauer J,Schober A,Löffler C,Seelbinder B,Hünniger K,Kurzai O,Scherag A,Schäuble S,Morton CO,Einsele H,Linde J,Löffler J

更新日期：2019-11-21 00:00:00

abstract：:Microbial rhodopsin is a photoreceptor protein found in various bacteria and archaea, and it is considered to be a light-utilization device unique to heterotrophs. Recent studies have shown that several cyanobacterial genomes also include genes that encode rhodopsins, indicating that these auxiliary light-utilizing pr...

journal_title：Scientific reports

authors： Hasegawa M,Hosaka T,Kojima K,Nishimura Y,Nakajima Y,Kimura-Someya T,Shirouzu M,Sudo Y,Yoshizawa S

更新日期：2020-10-07 00:00:00

abstract：:Parametric analysis of Cerebellar Ataxia (CA) could be of immense value compared to its subjective clinical assessments. This study focuses on a comprehensive scheme for objective assessment of CA through the instrumented versions of 9 commonly used neurological tests in 5 domains- speech, upper limb, lower limb, gait...

journal_title：Scientific reports

authors： Kashyap B,Phan D,Pathirana PN,Horne M,Power L,Szmulewicz D

更新日期：2020-06-11 00:00:00

abstract：:Manual anthropometrics are used extensively in medical practice and epidemiological studies to assess an individual's health. However, traditional techniques reduce the complicated shape of human bodies to a series of simple size measurements and derived health indices, such as the body mass index (BMI), the waist-hip...

journal_title：Scientific reports

authors： Thelwell M,Chiu CY,Bullas A,Hart J,Wheat J,Choppin S

更新日期：2020-07-22 00:00:00

abstract：:Human papillomavirus (HPV) infection, a primary cause of genital cancer, is also related to the increasing incidence of oropharyngeal cancer among young men. Relatively little is known about the concurrence of oral and genital infection among healthy individuals. Oral and genital swab exfoliated cells were collected s...

journal_title：Scientific reports

authors： Liu F,Hang D,Deng Q,Liu M,Xi L,He Z,Zhang C,Sun M,Liu Y,Li J,Pan Y,Ning T,Guo C,Liang Y,Xu R,Zhang L,Cai H,Ke Y

更新日期：2015-10-27 00:00:00

abstract：:Aquaporins (AQPs) are a ubiquitous family of transmembrane water channel proteins. A subgroup of AQP water channels also facilitates transmembrane diffusion of small, polar solutes. A constriction within the pore, the aromatic/arginine (ar/R) selectivity filter, is thought to control solute permeability: previous stud...

journal_title：Scientific reports

authors： Kitchen P,Salman MM,Pickel SU,Jennings J,Törnroth-Horsefield S,Conner MT,Bill RM,Conner AC

更新日期：2019-12-30 00:00:00

abstract：:Diagnosing stable ischemic heart disease (IHD) is challenging, especially in females. Currently, no blood test is available. Plasma extracellular vesicles (EV) are emerging as potential biomarker source. We therefore aimed to identify stress induced ischemia due to stable IHD with plasma extracellular vesicle protein ...

journal_title：Scientific reports

authors： Dekker M,Waissi F,van Bennekom J,Silvis MJM,Timmerman N,Bank IEM,Walter JE,Mueller C,Schoneveld AH,Schiffelers RM,Pasterkamp G,Grobbee DE,de Winter RJ,Mosterd A,de Kleijn DPV,Timmers L

更新日期：2020-07-23 00:00:00

abstract：:The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which is often associated with severe adverse effects. One strategy to reduce the adverse effects is targeted therapy that can selectively deliver anticancer drugs to tumor cells. Immature laminin receptor protein (OFA/iLRP) is a potential t...

journal_title：Scientific reports

authors： An Y,Hu Y,Li X,Li Z,Duan J,Yang XD

更新日期：2019-05-14 00:00:00

abstract：:In vertebrates, growth hormone/insulin-like growth factor (GH/IGF) axis signaling plays a critical role in regulating somatic growth. Understanding the direct upstream regulators of GH/IGF axis remains a major challenge. Our studies of the zebrafish reveal that the conserved miR-200 family members are critical regulat...

journal_title：Scientific reports

authors： Jing J,Xiong S,Li Z,Wu J,Zhou L,Gui JF,Mei J

更新日期：2015-10-28 00:00:00

abstract：:Longitudinal developmental fMRI studies just recently began to focus on within-subject reliability using the intraclass coefficient (ICC). It remains largely unclear which degree of reliability can be achieved in developmental studies and whether this depends on the type of task used. Therefore, we aimed to systematic...

journal_title：Scientific reports

authors： Vetter NC,Steding J,Jurk S,Ripke S,Mennigen E,Smolka MN

更新日期：2017-05-23 00:00:00

abstract：:Intracellular signal transduction involves a number of biochemical reactions, which largely consist of protein-protein interactions and protein conformational changes. Monitoring Förster resonance energy transfer (FRET) by fluorescence lifetime imaging microscopy (FLIM), called FLIM-FRET, is one of the best ways to vi...

journal_title：Scientific reports

authors： Nakahata Y,Nabekura J,Murakoshi H

更新日期：2016-12-22 00:00:00

abstract：:The natural bacterial diversity is regarded as a treasure trove for natural products. However, accessing complex cell mixtures derived from environmental samples in standardized high-throughput screenings is challenging. Here, we present a droplet-based microfluidic platform for ultrahigh-throughput screenings able to...

journal_title：Scientific reports

authors： Mahler L,Wink K,Beulig RJ,Scherlach K,Tovar M,Zang E,Martin K,Hertweck C,Belder D,Roth M

更新日期：2018-08-30 00:00:00

abstract：:Lariatin A, an 18-residue lasso peptide encoded by the five-gene cluster larABCDE, displays potent and selective anti-mycobacterial activity. The structural feature is an N-terminal macrolactam ring, through which the C-terminal passed to form the rigid lariat-protoknot structure. In the present study, we established ...

journal_title：Scientific reports

authors： Inokoshi J,Koyama N,Miyake M,Shimizu Y,Tomoda H

更新日期：2016-07-26 00:00:00