Abstract:
:The correlation between hepatitis B virus (HBV) infection and metabolic syndrome (MetS) remains to be clarified. In this study, we explored this association in a large population in Southwest China. This was a cross-sectional study, with pooled adult health data. Multivariate logistic regression analysis, controlling for age, sex, HBV status, alanine aminotransferase, and fatty liver, was used to identify predictor(s) of MetS. Of the 96,175 participants, positive HBV was identified in 7984 (8.30%) and MetS in 12,092 (12.57%). The MetS prevalence was lower among HBV positive than negative individuals (11.64% versus 12.66%, P < 0.001). The adjusted odds (aOR) of positive HBV among individuals with MetS was 0.841 (95% confidence interval (CI), 0.771-0.916) in men and 0.834 (95% CI, 0.672-0.925) in women. Elevated triglyceride level, a component of MetS, was inversely associated with HBV status in both men and women: aOR, 0.551 (95% CI, 0.514-0.590) and 0.683 (95% CI, 0.605-0.769), respectively. Among HBV positive individuals, liver cirrhosis was more common among those with than without MetS (4.83% versus 2.93%, respectively; P = 0.002). HBsAg-seropositive are inversely associated with MetS, especially elevated triglycerides. Liver cirrhosis was more common among HBV infection patients with MetS.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yan LB,Liao J,Han N,Zhou LY,Wang XE,Wang YJ,Tang Hdoi
10.1038/s41598-020-62609-4subject
Has Abstractpub_date
2020-04-21 00:00:00pages
6738issue
1issn
2045-2322pii
10.1038/s41598-020-62609-4journal_volume
10pub_type
杂志文章abstract::Biological armors such as mollusk shells have long been recognized and studied for their values in inspiring novel designs of engineering materials with higher toughness and strength. However, no material is invincible and biological armors also have their rivals. In this paper, our attention is focused on the teeth o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23509
更新日期:2016-03-22 00:00:00
abstract::Given the rapidly expanding library of disease biomarkers and targeting agents, the number of unique targeted nanoparticles is growing exponentially. The high variability and expense of animal testing often makes it unfeasible to examine this large number of nanoparticles in vivo. This often leads to the investigation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05840
更新日期:2014-07-28 00:00:00
abstract::Circulating levels of Brain Derived Neurotrophic Factor (BDNF) are lower in coronary heart disease (CHD) than in healthy subjects and are associated with coronary events and mortality. However, the mechanism(s) underling this association is not fully understood. We hypothesize that BDNF may influence fibrin fiber stru...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-018-37117-1
更新日期:2019-01-23 00:00:00
abstract::Pesticides are the main tactics for pest control because they reduce the pest population very fast and their efficiency does not depend on abiotic factors. However, the indiscriminate use of these substances can speed up the development of resistant populations and causing environmental contamination. Therefore, alter...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26043-x
更新日期:2018-05-16 00:00:00
abstract::To overcome drug resistance caused by apoptosis deficiency in patients with non-small cell lung carcinoma (NSCLC), there is a need to identify other means of triggering apoptosis-independent cancer cell death. We are the first to report that isogambogenic acid (iso-GNA) can induce apoptosis-independent autophagic cell...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07697
更新日期:2015-01-09 00:00:00
abstract::We show an annual overview of the sea-air CO2 exchanges and primary drivers in the Gerlache Strait, a hotspot for climate change that is ecologically important in the northern Antarctic Peninsula. In autumn and winter, episodic upwelling events increase the remineralized carbon in the sea surface, leading the region t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71814-0
更新日期:2020-09-10 00:00:00
abstract::Saccharomyces cerevisiae is a robust host for heterologous protein expression. The efficient expression of cellulases in S. cerevisiae is important for the consolidated bioprocess that directly converts lignocellulose into valuable products. However, heterologous proteins are often N-hyperglycosylated in S. cerevisiae...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25654
更新日期:2016-05-09 00:00:00
abstract::Measurements of volcanic tephra fallout deposits provide useful information about the magnitude and intensity of explosive volcanic eruptions and potential for remobilization of deposits as dangerous volcanic flows. However, gathering information in the vicinity of erupting craters is extremely dangerous, and moreover...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71902-1
更新日期:2020-09-09 00:00:00
abstract::We describe a high resolution laser polarimeter built from commodity optical components. The optical rotation angle is determined by measuring the phase difference between two harmonically modulated polarised laser beams - an 'object beam' that passes through the sample under test and a 'reference beam' that bypasses ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61715-7
更新日期:2020-03-25 00:00:00
abstract::The subjective experience of thermal pain follows the detection and encoding of noxious stimuli by primary afferent neurons called nociceptors. However, nociceptor morphology has been hard to access and the mechanisms of signal transduction remain unresolved. In order to understand how heat transducers in nociceptors ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17670
更新日期:2015-12-07 00:00:00
abstract::Herein, water-oxidation reaction by cobalt(II) phthalocyanine, N,N'-bis (salicylidene) ethylenediamino cobalt(II), nickel(II) Schiff base (N,N'-bis (salicylidene)ethylenediamino nickel(II), nickel(II)) phthalocyanine-tetrasulfonate tetrasodium, manganese(II) phthalocyanine, 5,10,15,20-Tetraphenyl-21H,23H-porphine mang...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43953-6
更新日期:2019-05-16 00:00:00
abstract::Huntington's disease (HD) is a neurodegenerative disorder whose major symptoms include progressive motor and cognitive dysfunction. Cognitive decline is a critical quality of life concern for HD patients and families. The enzyme histone deacetylase 3 (HDAC3) appears to be important in HD pathology by negatively regula...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05125-2
更新日期:2017-07-20 00:00:00
abstract::MITF is a known gene underlying autosomal dominant hearing loss, Waardenburg syndrome (WS). Biallelic MITF mutations have been found associated with a rare hearing loss syndrome consisting eye abnormalities and albinism; and a more severe type of WS whose heterozygous parents were affected with classic WS in both case...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69633-4
更新日期:2020-07-29 00:00:00
abstract::The transcriptome of the endometrium early postpartum was profiled to determine if inflammatory gene expression was elevated in cows which subsequently developed uterine disease. Endometrial cytobrush samples were collected at 7 days postpartum (DPP) from 112 Holstein-Friesian dairy cows, from which 27 were retrospect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75104-7
更新日期:2020-10-26 00:00:00
abstract::Polyelectrolyte-coated nanoparticles consisting of terbium and gadolinium complexes with calix[4]arene tetra-diketone ligand were first synthesized. The antenna effect of the ligand on Tb(III) green luminescence and the presence of water molecules in the coordination sphere of Gd(III) bring strong luminescent and magn...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40486
更新日期:2017-01-16 00:00:00
abstract::Quantum walk is a key operation in quantum computing, simulation, communication and information. Here, we report for the first time the demonstration of quantum walks and localized quantum walks in a new type of optical fibers having a ring of cores constructed with both periodic and quasiperiodic Fibonacci sequences,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64065-6
更新日期:2020-04-28 00:00:00
abstract::Colloidal particles immersed in a dynamic speckle pattern experience an optical force that fluctuates both in space and time. The resulting dynamics presents many interesting analogies with a broad class of non-equilibrium systems like: active colloids, self propelled microorganisms, transport in dynamical intracellul...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27681
更新日期:2016-06-09 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-60642-x
更新日期:2020-02-21 00:00:00
abstract::One of the most exciting areas in lithium ion batteries is engineering structured silicon anodes. These new materials promise to lead the next generation of batteries with significantly higher reversible charge capacity than current technologies. One drawback of these materials is that their production involves costly...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00795
更新日期:2012-01-01 00:00:00
abstract::Ulvan, which is one of the major structural polysaccharides of the cell walls of green macroalgae, is degraded by ulvan lyases via the β-elimination mechanism with the release of oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (∆) at the non-reducing end. These ulvan lyases belong ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32922-0
更新日期:2018-10-02 00:00:00
abstract::While neurofilament light chain (NfL) measurement in serum is a well-established marker of neuroaxonal damage in multiple sclerosis (MS), data on astroglial markers in serum are missing. In our study, glial fibrillary acid protein (GFAP) and NfL were measured in cerebrospinal fluid (CSF) and serum of MS patients and p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33158-8
更新日期:2018-10-04 00:00:00
abstract::Accurate characterization of the mechanical properties of brain tissue is essential for understanding the mechanisms of traumatic brain injuries and developing protective gears or facilities. However, how storage conditions might affect the mechanical properties of brain tissue remains unclear. The objective of this s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19687-2
更新日期:2018-01-19 00:00:00
abstract::Species and populations are disappearing at an alarming rate as a direct result of human activities. Loss of genetic diversity associated with population decline directly impacts species' long-term survival. Therefore, preserving genetic diversity is of considerable conservation importance. However, to assist in conse...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24497-7
更新日期:2018-04-25 00:00:00
abstract::R-loops are RNA-DNA hybrid sequences that are emerging players in various biological processes, occurring in both prokaryotic and eukaryotic cells. In viruses, R-loop investigation is limited and functional importance is poorly understood. Here, we performed a computational approach to investigate prevalence, distribu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63101-9
更新日期:2020-04-14 00:00:00
abstract::The annotation of protein function is a vital step to elucidate the essence of life at a molecular level, and it is also meritorious in biomedical and pharmaceutical industry. Developments of sequencing technology result in constant expansion of the gap between the number of the known sequences and their functions. Th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37179
更新日期:2016-11-16 00:00:00
abstract::Adropin is a peptide hormone encoded by the Energy Homeostasis Associated (ENHO) gene whose physiological role in humans remains incompletely defined. Here we investigated the impact of dietary interventions that affect systemic glucose and lipid metabolism on plasma adropin concentrations in humans. Consumption of gl...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/srep14691
更新日期:2015-10-05 00:00:00
abstract::The sensory neurons in the olfactory epithelium (OSNs) are equipped with a large repertoire of olfactory receptors and the associated signal transduction machinery. In addition to the canonical OSNs, which express odorant receptors (ORs), the epithelium contains specialized subpopulations of sensory neurons that can d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25507
更新日期:2016-05-05 00:00:00
abstract::ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the ARTs that catalyse ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43750
更新日期:2017-03-02 00:00:00
abstract::We found the first evidence, in the last 30 years, of a renewed magmatic activity at Campi Flegrei caldera from January 2012 to June 2013. The ground deformation, observed through satellite interferometry and GPS measurements, have been interpreted as the effect of the intrusion at shallow depth (3090 ± 138 m) of 0.00...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13100
更新日期:2015-08-17 00:00:00
abstract::Superresolution microscopy offers the advantage of imaging biological structures within cells at the nano-scale. Here we apply two superresolution microscopy techniques, specifically 3D structured illumination microscopy (3D-SIM) and direct stochastic optical reconstruction microscopy (dSTORM), a type of single molecu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38851-w
更新日期:2019-02-21 00:00:00