Abstract：
:Polyelectrolyte-coated nanoparticles consisting of terbium and gadolinium complexes with calix[4]arene tetra-diketone ligand were first synthesized. The antenna effect of the ligand on Tb(III) green luminescence and the presence of water molecules in the coordination sphere of Gd(III) bring strong luminescent and magnetic performance to the core-shell nanoparticles. The size and the core-shell morphology of the colloids were studied using transmission electron microscopy and dynamic light scattering. The correlation between photophysical and magnetic properties of the nanoparticles and their core composition was highlighted. The core composition was optimized for the longitudinal relaxivity to be greater than that of the commercial magnetic resonance imaging (MRI) contrast agents together with high level of Tb(III)-centered luminescence. The tuning of both magnetic and luminescent output of nanoparticles is obtained via the simple variation of lanthanide chelates concentrations in the initial synthetic solution. The exposure of the pheochromocytoma 12 (PC 12) tumor cells and periphery human blood lymphocytes to nanoparticles results in negligible effect on cell viability, decreased platelet aggregation and bright coloring, indicating the nanoparticles as promising candidates for dual magneto-fluorescent bioimaging.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zairov R,Mustafina A,Shamsutdinova N,Nizameev I,Moreira B,Sudakova S,Podyachev S,Fattakhova A,Safina G,Lundstrom I,Gubaidullin A,Vomiero Adoi
10.1038/srep40486subject
Has Abstractpub_date
2017-01-16 00:00:00pages
40486issn
2045-2322pii
srep40486journal_volume
7pub_type
杂志文章abstract：:Sarcopenia is defined as skeletal muscle attenuation and has an association with metabolic syndrome. Metabolic syndrome, which includes obesity, is one of known predictive factors for gastroesophageal reflux disease (GERD). This study aimed to elucidate the association between sarcopenia and GERD. We retrospectively r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56702-6
更新日期：2019-12-27 00:00:00
abstract：:Human CD4+ T cells play an important role in the immune response to Mycobacterium tuberculosis (MTB). However, little is known about the spectratyping characteristics of the CD4+ T-cell receptor (TCR) α- and β-chains CDR3 region in tuberculosis (TB) patients. We sorted MTB peptide E7-bound CD4+ T cells by using E7/HLA...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28344-7
更新日期：2018-07-02 00:00:00
abstract：:The artificial earthquake of mb 6.1 related to the North Korea's sixth nuclear test occured at Mt. Mantap, North Korea on September 3, 2017. It was reported that a large and complex surface deformation was caused by the event. The surface deformation was composed of expansion of explosions, collapse, compaction and la...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-74957-2
更新日期：2020-10-20 00:00:00
abstract：:Gold standard quantitative nucleic acid tests for diagnosis of viral diseases are currently limited to implementation in laboratories outside of the clinic. An instrument for conducting nucleic acid testing at the point-of-care (POC) that is easily operable by the clinician would reduce the required number of visits t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28124-3
更新日期：2018-06-28 00:00:00
abstract：:Global temperature changes have emphasized the need to understand how species adapt to thermal stress across their ranges. Genetic mechanisms may contribute to variation in thermal tolerance, providing evidence for how organisms adapt to local environments. We determine physiological thermal limits and characterize ge...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73391-8
更新日期：2020-10-13 00:00:00
abstract：:Mitofusins are large transmembrane GTPases of the dynamin-related protein family, and are required for the tethering and fusion of mitochondrial outer membranes. Their full-length structures remain unknown, which is a limiting factor in the study of outer membrane fusion. We investigated the structure and dynamics of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10687-2
更新日期：2017-08-31 00:00:00
abstract：:A major unresolved question in understanding visually guided locomotion in humans is whether actions are driven solely by the immediately available optical information (model-free online control mechanisms), or whether internal models have a role in anticipating the future path. We designed two experiments to investig...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44723-0
更新日期：2019-06-06 00:00:00
abstract：:Various nickel and magnesium dual-doped LiNixMg0.08Mn1.92-xO4 (x ≤ 0.15) were synthesized via a modified solid-state combustion method. All as-prepared samples show typical spinel phase with a well-defined polyhedron morphology. The Ni-Mg dual-doping obviously decreases the lattice parameter that gives rise to the lat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53494-7
更新日期：2019-11-14 00:00:00
abstract：:A novel protein, designated as DOI, isolated from the Chinese yam (Dioscorea opposita Thunb.) could be the first protein drug for the treatment of menopausal syndrome and an alternative to hormone replacement therapy (HRT), which is known to have undesirable side effects. DOI is an acid- and thermo-stable protein with...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10179
更新日期：2015-07-10 00:00:00
abstract：:Horizontal gene transfer (HGT) is a main mechanism of bacterial evolution endowing bacteria with new genetic traits. The transfer of mobile genetic elements such as plasmids (conjugation) requires the close proximity of cells. HGT between genetically distinct bacteria largely depends on cell movement in water films, w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36390
更新日期：2016-11-04 00:00:00
abstract：:Polymer-derived silicon oxycarbide (SiCO) presents excellent performance for high temperature and lithium-ion battery applications. Current experiments have provided some information on nano-structure of SiCO, while it is very challenging for experiments to take further insight into the molecular structure and its rel...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42705
更新日期：2017-02-14 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-58958-9
更新日期：2020-02-19 00:00:00
abstract：:Mesenchymal stromal cells (MSC) are used in cell therapies, however cellular senescence increases heterogeneity of cell populations and leads to uncertainty in therapies' outcomes. The determination of cellular senescence is time consuming and logistically intensive. Here, we propose the use of endogenous autofluoresc...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38546-2
更新日期：2019-02-14 00:00:00
abstract：:Genome editing tools have revolutionized the generation of genetically modified animals including livestock. In particular, the domestic pig is a proven model of human physiology and an agriculturally important species. In this study, we utilized the CRISPR/Cas9 system to edit the NANOS2 gene in pig embryos to generat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40176
更新日期：2017-01-10 00:00:00
abstract：:Hypertension and diabetes mellitus (DM) have become major public health issues, and previous studies have shown that there is an association between hypertension and DM. However, there is a lack of detailed information about this association. This study aimed to explore how different blood pressure (BP) levels were as...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26323-6
更新日期：2018-05-21 00:00:00
abstract：:Gliomas are the most common brain tumors affecting the central nervous system and are associated with a high mortality rate. DCF1 is a membrane protein that was previously found to play a role in neural stem cell differentiation. In the present study, we found that overexpression of dcf1 significantly inhibited cell p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03702
更新日期：2014-01-15 00:00:00
abstract：:In the present work, TiO2 nanoparticle and multi-walled carbon nanotubes composite powder is prepared hydrothermally. After doctor blading the paste from composite powder, the resulted composite film is sensitized with Cu-based metal-organic frameworks using a layer-by-layer deposition technique and the film is charac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03930
更新日期：2014-02-03 00:00:00
abstract：:Phytoplasmas (class, Mollicutes) are insect-transmissible and plant-pathogenic bacteria that multiply intracellularly in both plants and insects through host switching. Our previous study revealed that phytoplasmal sigma factor rpoD of OY-M strain (rpoDOY) could be a key regulator of host switching, because the expres...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11893
更新日期：2015-07-07 00:00:00
abstract：:Multiple sources of sensory information are combined to develop hand posture percepts in the intact system, but the combination of multiple artificial somatosensory percepts by human prosthesis users has not been studied. Here, we report on a case study in which a person with transradial amputation identified prosthet...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62970-4
更新日期：2020-04-20 00:00:00
abstract：:Smart nanoparticles (NPs) that respond to external and internal stimulations have been developing to achieve optimal drug release in tumour. However, applying these smart NPs to attain high antitumour performance is hampered by limited drug carriers and inefficient spatiotemporal control. Here we report a noninvasive ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14258
更新日期：2015-09-24 00:00:00
abstract：:Quantitative magnetic resonance imaging (qMRI) is a versatile, non-destructive and non-invasive tool in life, material, and medical sciences. When multiple components contribute to the signal in a single pixel, however, it is difficult to quantify their individual contributions and characteristic parameters. Here we i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00864-8
更新日期：2017-04-13 00:00:00
abstract：:The risk of suffering from Alzheimer's disease (AD) is higher in individuals from AD-affected mothers. The purpose of this investigation was to study whether maternal transmission might produce AD-related alterations in progenies of mice that do not have any genotypic alteration. We used cognitively-intact mothers har...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24710-7
更新日期：2018-04-24 00:00:00
abstract：:Nanospheres of lead (Pb) have recently been identified in zircon (ZrSiO4) with the potential to compromise the veracity of U-Pb age determinations. The key assumption that the determined age is robust against the effects of Pb mobility, as long as Pb is not lost from the zircon during subsequent geological events, is ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49882-8
更新日期：2019-09-23 00:00:00
abstract：:Cathode materials always limit the performance of fuel cells while the commercial platinum-based catalysts hardly meet the requirements of low cost, durable and stable. Here a non-precious metal oxygen reduction reaction (ORR) electocatalyst based on titanium nitride/titanium carbonitride hierarchical structures (TNTC...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06712
更新日期：2014-10-22 00:00:00
abstract：:Detection of antihypertensive drugs in biological samples is an important tool to assess the adherence of hypertensive patients. Urine and serum/plasma screenings based on qualitative results may lead to misinterpretations regarding drugs with a prolonged detectability. The aim of the present study was to develop a me...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52164-y
更新日期：2019-10-30 00:00:00
abstract：:A challenge in regenerating large bone defects under load is to create scaffolds with large and interconnected pores while providing a compressive strength comparable to cortical bone (100-150 MPa). Here we design a novel hexagonal architecture for a glass-ceramic scaffold to fabricate an anisotropic, highly porous th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19468
更新日期：2016-01-19 00:00:00
abstract：:Plants are continuously exposed to myriad pathogen stresses. However, the molecular mechanisms by which these stress signals are perceived and transduced are poorly understood. In this study, the maize gene GRMZM2G315431 was identified to be highly inducible by Rhizoctonia solani infection, suggesting that the promote...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42059
更新日期：2017-02-06 00:00:00
abstract：:A new, composite plasmonic waveguide based electromagnetic cloaking scheme is proposed with Si nano-spacer. Here we show, that the scattering fields of an object located on the cloak do not interact with the evanescent field, resulting in object's invisibility. Finite difference time domain (FDTD) numerical calculatio...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10578-6
更新日期：2017-09-21 00:00:00
abstract：:Precision Medicine in Oncology requires tailoring of therapeutic strategies to individual cancer patients. Due to the limited quantity of tumor samples, this proves to be difficult, especially for early stage cancer patients whose tumors are small. In this study, we exploited a 2.4 × 2.4 centimeters polydimethylsiloxa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08831-z
更新日期：2017-08-22 00:00:00
abstract：:This study cross-sectionally examines in the elderly population: (a) the association of type 2 diabetes with executive function (EF); (b) the effect of BMI on both type 2 diabetes and EF; (c) the association between glycaemia control and EF in type 2 diabetes. 6823 older individuals with overweight/obesity and metabol...
journal_title：Scientific reports
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1038/s41598-018-33843-8
更新日期：2018-10-31 00:00:00
