Abstract:
:We aimed to model longitudinal data to create predictive growth charts for weight in preterm infants from birth till discharge, that took into account the differing growth rates post-birth when compared to in-utero growth and therefore was more representative of the data than the UK1990 reference charts. Data from birth until discharge (or death), was collected and rigorously cleaned for all infants born at <32 weeks of gestation over a 4-year period. Means and standard deviations from the UK1990 reference charts were used to compute standard deviation scores (SDS) for our cohort. 2/3rd of the data was randomly selected and used to create gestation and gender-specific predictive weight centile lines through novel application of mixed modelling methods. The remaining 1/3rd of the data was used to test model fit by comparing expected vs actual weights for the new model with those predicted by the UK1990 model. Data from 1,510 preterm infants was analysed. 1067 of these were used to produce the predictive model. Weekly SDS were significantly lower than predicted throughout hospital stay for all gestation groups when compared with UK1990 data. The test data (n = 539) fitted the new centile lines substantially better than those modelled by the UK1990 centile lines. Mixed modelling of longitudinal data produced new predictive references for weight centiles of preterm infants. A large population-based prospective study is needed to produce representative longitudinal reference growth charts using these methods.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Watkins WJ,Farewell D,Banerjee S,Nasef H,James A,Chakraborty Mdoi
10.1038/s41598-020-60895-6subject
Has Abstractpub_date
2020-03-04 00:00:00pages
4032issue
1issn
2045-2322pii
10.1038/s41598-020-60895-6journal_volume
10pub_type
杂志文章abstract::The Hauraki Gulf, a shallow embayment in north-eastern New Zealand, provides an interesting environment for ecological soundscape research. It is situated on a tectonic plate boundary, contains one of the busiest ports in the southern hemisphere and is home to a diverse range of soniferous animals. The underwater soun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06347-0
更新日期:2017-07-18 00:00:00
abstract::We investigate the Lorentz-covariant deformed algebra for Dirac oscillator problem, which is a generalization of Kempf deformed algebra in 3 + 1 dimension of space-time, where Lorentz symmetry are preserved. The energy spectrum of the system is analyzed by taking advantage of the corresponding wave functions with expl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03221
更新日期:2013-11-14 00:00:00
abstract::When realising future fusion reactors, their stationary burning must be maintained and the heat flux to the divertor must be reduced. This essentially requires a stationary internal transport barrier (ITB) plasma with a fast control system. However, the time scale for determining the position of the foot point of an I...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56492-x
更新日期:2020-01-08 00:00:00
abstract::The most downstream elements of the Hippo pathway, the TEAD transcription factors, are regulated by several cofactors, such as Vg/VGLL1-3. Earlier findings on human VGLL1 and here on human VGLL3 show that these proteins interact with TEAD via a conserved amino acid motif called the TONDU domain. Surprisingly, our stud...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74584-x
更新日期:2020-10-15 00:00:00
abstract::Evidence on the association between dietary fiber intake and pancreatic cancer risk has been controversial. Therefore, we carried out this meta-analysis to summarize available evidence from epidemiologic studies on this point. Relevant studies were identified by searching PubMed, Embase and Web of Science databases as...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep10834
更新日期:2015-06-02 00:00:00
abstract::The recent emergence of highly virulent human adenoviruses (HAdVs) with new tissue tropisms underscores the need to determine their ontogeny. Here we report complete high quality genome sequences and analyses for all the previously unsequenced HAdV serotypes (n = 20) within HAdV species D. Analysis of nucleotide seque...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01812
更新日期:2013-01-01 00:00:00
abstract::At the Ediacaran/Cambrian boundary, ecosystems witnessed an unparalleled biological innovation: the appearance of shelled animals. Here, we report new paleoecological and paleobiological data on Cloudina, which was one of the most abundant shelled animals at the end of the Ediacaran. We report the close association of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05753-8
更新日期:2017-07-14 00:00:00
abstract::The expanding distribution of African swine fever (ASF) is threatening the pig industry worldwide. Most outbreaks occur in backyard and small-scale herds, where poor farmers often attempt to limit the disease's economic consequences by the emergency sale of their pigs. The risk of African swine fever virus (ASFV) rele...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17074
更新日期:2015-11-27 00:00:00
abstract::Traditionally, the practice of the tibial component placement in total knee arthroplasty has focused on achieving maximum coverage without malrotation. However, the concept of maximizing coverage has not been well defined or researched and yet biased results are often produced. This study aimed to evaluate the effect ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67613-2
更新日期:2020-06-29 00:00:00
abstract::Many neurological diseases present with substantial genetic and phenotypic heterogeneity, making assessment of these diseases challenging. This has led to ineffective treatments, significant morbidity, and high mortality rates for patients with neurological diseases, including brain cancers and neurodegenerative disor...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74459-1
更新日期:2020-10-14 00:00:00
abstract::This study aimed to investigate the possible association between diabetes susceptibility gene transcription factor 7-like 2 (TCF7L2) and gestational diabetes mellitus (GDM) in a Chinese Han population. A total of 556 GDM patients and 500 Non-GDM were included. Eighteen single nucleotide polymorphisms (SNPs) were evalu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30686
更新日期:2016-07-28 00:00:00
abstract::Deficits in GABAergic inhibitory neurotransmission are a reliable finding in schizophrenia (SCZ) patients. Previous studies have reported that unaffected first-degree relatives of patients with SCZ demonstrate neurophysiological abnormalities that are intermediate between probands and healthy controls. In this study, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43629
更新日期:2017-02-27 00:00:00
abstract::Luminescent zeolites exchanged with two distinct and interacted emissive ions are vital but less-studied for the potential applications in white light emitting diodes, solar cells, optical codes, biomedicine and so on. Typical transition metal ion Mn2+ and lanthanide ion Yb3+ are adopted as a case study via their char...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46219
更新日期:2017-04-10 00:00:00
abstract::Our study focused on radiocaesium (137Cs) partitioning in forests, three vegetation periods after the Fukushima Daiichi nuclear power plant accident. 137Cs distribution in forest components (organic and mineral soil layers as well as tree compartments: stem, bark, needles, branches and roots) was measured for two Japa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37618
更新日期:2016-11-23 00:00:00
abstract::Bast fibres are long extraxylary cells which mechanically support the phloem and they are divided into xylan- and gelatinous-type, depending on the composition of their secondary cell walls. The former, typical of jute/kenaf bast fibres, are characterized by the presence of xylan and a high degree of lignification, wh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05200-8
更新日期:2017-07-10 00:00:00
abstract::Incredible accomplishments have been achieved in agricultural production in China, but many demanding challenges for ensuring food security and environmental sustainability remain. Field experiments were conducted from 2011-2013 at three different sites, including Honghu, Shayang, and Jingzhou in China, to determine t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01412-0
更新日期:2017-04-28 00:00:00
abstract::Switching magnetizations with femtosecond circularly polarized lasers may have revolutionary impacts on magnetic data storage and relevant applications. Achievements in ferrimagnetic and ferromagnetic materials of various structures strongly imply a general phenomenon of fundamental atom-laser interaction. Rotating an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41294
更新日期:2017-01-24 00:00:00
abstract::Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18887-6
更新日期:2018-01-12 00:00:00
abstract::A three dimensional (3D) numerical solution of unsteady, Ag-MgO hybrid nanoliquid flow with heat and mass transmission caused by upward/downward moving of wavy spinning disk has been scrutinized. The magnetic field has been also considered. The hybrid nanoliquid has been synthesized in the presence of Ag-MgO nanoparti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75905-w
更新日期:2020-11-02 00:00:00
abstract::To face the great challenges of ensuring food security and environmental sustainability, agricultural production must be improved by high yield and high resource utilization efficiency (HYHE). We recently addressed this challenge and evaluated yield potential by surveying 735 farmers in 2008-2012 and then conducting 6...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-02338-3
更新日期:2017-05-18 00:00:00
abstract::The familial forms of early onset pre-eclampsia and related syndromes (HELLP) present with hypertension and proteinuria in the mother and growth restriction of the fetus. Genetically, these clinically similar entities are caused by different founder-dependent, placentally-expressed paralogous genes. All susceptibility...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep32129
更新日期:2016-08-24 00:00:00
abstract::Isolation of low abundance proteins or rare cells from complex mixtures, such as blood, is required for many diagnostic, therapeutic and research applications. Current affinity-based protein or cell separation methods use binary 'bind-elute' separations and are inefficient when applied to the isolation of multiple low...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23589
更新日期:2016-03-30 00:00:00
abstract::Currently, there is no appropriate treatment option for patients with sorafenib-resistant hepatocellular carcinoma (HCC). Meanwhile, pronounced anticancer activities of newly-developed mitochondria-accumulating self-assembly peptides (Mito-FF) have been demonstrated. This study intended to determine the anticancer eff...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79536-z
更新日期:2021-01-13 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-75647-9
更新日期:2020-10-29 00:00:00
abstract::Visible indication based on the aggregation of colloidal nanoparticles (NPs) is highly advantageous for rapid on-site detection of biological entities, which even untrained persons can perform without specialized instrumentation. However, since the extent of aggregation should exceed a certain minimum threshold to pro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00456
更新日期:2012-01-01 00:00:00
abstract::Intrasynovial tendon injuries are among the most challenging in orthopedics. Despite significant improvements in operative and rehabilitation methods, functional outcomes continue to be limited by adhesions, gap formation, and rupture. Adhesions result from excessive inflammation, whereas tendon gapping and rupture re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29474-8
更新日期:2018-07-23 00:00:00
abstract::Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19507-7
更新日期:2018-01-18 00:00:00
abstract::β1 integrin regulates the response of both normal and cancer cells to their local environment. Although mis-localised in prostate cancer, the role β1 integrin plays in prostate development and carcinogenesis remains unknown. To assess the role of β1 integrin in vivo, we conditionally deleted β1 integrin from prostate ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00526
更新日期:2012-01-01 00:00:00
abstract::While designing the anti-inflammatory agents targeting cyclooxygenase-2 (COX-2), we first identified a water loop around the heme playing critical role in the enzyme catalysis. The results of molecular dynamic studies supported by the strong hydrogen-bonding equilibria of the participating atoms, radical stabilization...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67655-6
更新日期:2020-07-01 00:00:00
abstract::Intraperitoneal administration of antibiotics together with peritoneal dialysis fluids (PDFs) remains the preferable route for treatment of peritoneal dialysis-related peritonitis. For home based therapy, antibiotic-containing PDFs are stored for up to two weeks and warmed up to body-temperature before administration....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-42854-y
更新日期:2019-04-24 00:00:00