Nanodiamond landmarks for subcellular multimodal optical and electron imaging.

abstract：:SLC30A2 encodes a zinc (Zn) transporter (ZnT2) that imports Zn into vesicles in highly-specialized secretory cells. Numerous mutations and non-synonymous variants in ZnT2 have been reported in humans and in breastfeeding women; ZnT2 variants are associated with abnormally low milk Zn levels and can lead to severe infa...

journal_title：Scientific reports

authors： Lee S,Zhou Y,Gill DL,Kelleher SL

更新日期：2018-02-23 00:00:00

abstract：:Visceral leishmaniasis (VL) is a fatal form of leishmaniasis which affects 70 countries, worldwide. Increasing drug resistance, HIV co-infection, and poor health system require operative vaccination strategy to control the VL transmission dynamics. Therefore, a holistic approach is needed to generate T and B memory ce...

journal_title：Scientific reports

authors： Khatoon N,Pandey RK,Prajapati VK

更新日期：2017-08-15 00:00:00

abstract：:Numerous neurological dysfunctions are characterized by undesirable nerve activity. By providing reversible nerve blockage, electric stimulation with an implanted electrode holds promise in the treatment of these conditions. However, there are several limitations to its application, including poor bio-compatibility an...

journal_title：Scientific reports

authors： Skach J,Conway C,Barrett L,Ye H

更新日期：2020-10-22 00:00:00

abstract：:The taxa of Astragalus section Hymenostegis are an important element of mountainous and steppe habitats in Southwest Asia. A phylogenetic hypothesis of sect. Hymenostegis has been obtained from nuclear ribosomal DNA internal transcribed spacer (ITS) and plastid ycf1 sequences of up to 303 individuals from 106 species,...

journal_title：Scientific reports

authors： Bagheri A,Maassoumi AA,Rahiminejad MR,Brassac J,Blattner FR

更新日期：2017-10-25 00:00:00

abstract：:In this paper, we present an evolutionary trust game, taking punishment and protection into consideration, to investigate the formation of trust in the so-called sharing economy from a population perspective. This sharing economy trust model comprises four types of players: a trustworthy provider, an untrustworthy pro...

journal_title：Scientific reports

authors： Chica M,Chiong R,Adam MTP,Teubner T

更新日期：2019-12-24 00:00:00

abstract：:Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy. In this study, we report the development of a novel DNAzyme that can efficiently cle...

journal_title：Scientific reports

authors： Chakravarthy M,Aung-Htut MT,Le BT,Veedu RN

更新日期：2017-05-09 00:00:00

abstract：:Adenoviruses are very efficient vectors for delivering therapeutic genes in preclinical and clinical trials. However, randomized controlled human trials have often been lacking clear clinically relevant results. We hypothesized that high lipid levels and specific lipoproteins could significantly decrease adenoviral tr...

journal_title：Scientific reports

authors： Kivelä AM,Huusko J,Gurzeler E,Laine A,Dijkstra MH,Dragneva G,Andersen CB,Moestrup SK,Ylä-Herttuala S

更新日期：2017-03-24 00:00:00

abstract：:A number of studies have suggested that the irradiation behavior and damage processes occurring during sequential and simultaneous particle irradiations can significantly differ. Currently, there is no definite answer as to why and when such differences are seen. Additionally, the conventional multi-particle irradiati...

journal_title：Scientific reports

authors： Mir AH,Toulemonde M,Jegou C,Miro S,Serruys Y,Bouffard S,Peuget S

更新日期：2016-07-28 00:00:00

abstract：:SiO2 is the most significantly used insulator layer in semiconductor devices. Its functionality was recently extended to resistance switching random access memory, where the defective SiO2 played an active role as the resistance switching (RS) layer. In this report, the bias-polarity-dependent RS behaviours in the top...

journal_title：Scientific reports

authors： Jiang H,Li XY,Chen R,Shao XL,Yoon JH,Hu X,Hwang CS,Zhao J

更新日期：2016-02-26 00:00:00

abstract：:Cyclophilin A (CyPA), secreted by vascular smooth muscle cells in response to oxidative stress, is important in the pathogenesis of progressive peripheral arterial occlusion disease (PAOD), which is common among chronic kidney disease. We explored the prevalence of PAOD in Taiwan's elderly (≥ 65 years old) population ...

journal_title：Scientific reports

authors： Liu MC,Lee YW,Lee PT,Chang CS,Tai YL,Yu JR,Su XT,Hsu LW,Lin SH,Wu CH,Liu PY

更新日期：2015-04-24 00:00:00

abstract：:Circulating tumor cells (CTCs) are important clinical indicators for prognosis and treatment efficacy. However, CTC investigation is hampered by their low number, making the establishment of permanent CTC lines very challenging. We derived and characterized nine CTC lines using blood samples from a patient with metast...

journal_title：Scientific reports

authors： Soler A,Cayrefourcq L,Mazard T,Babayan A,Lamy PJ,Assou S,Assenat E,Pantel K,Alix-Panabières C

更新日期：2018-10-29 00:00:00

abstract：:The exopeptidases of family S46 are exceptional, as the closest homologs of these enzymes are the endopeptidases of clan PA. The three-dimensional structure of S46 enzymes is unknown and only one of the catalytic residues, the serine, has been identified. The catalytic histidine and aspartate residues are not experime...

journal_title：Scientific reports

authors： Suzuki Y,Sakamoto Y,Tanaka N,Okada H,Morikawa Y,Ogasawara W

更新日期：2014-03-06 00:00:00

abstract：:In this paper, we investigate the magnetic behavior of a single-walled hexagonal spin-1 Ising nanotube by using the effective field theory (EFT) with correlations and the differential operator technique (DOT). The system consists of six long legs distributed parallel to each other on a hexagonal basis. Within each cha...

journal_title：Scientific reports

authors： ElMaddahi Z,El Hafidi MY,El Hafidi M

更新日期：2019-08-26 00:00:00

abstract：:Horizontal gene transfer (HGT) is a main mechanism of bacterial evolution endowing bacteria with new genetic traits. The transfer of mobile genetic elements such as plasmids (conjugation) requires the close proximity of cells. HGT between genetically distinct bacteria largely depends on cell movement in water films, w...

journal_title：Scientific reports

authors： Berthold T,Centler F,Hübschmann T,Remer R,Thullner M,Harms H,Wick LY

更新日期：2016-11-04 00:00:00

abstract：:The ultrathin SmCo5 nanoflakes with average thickness smaller than 50 nm are prepared by a novel method of solid particle (NaCl) and surfactant co-assisted ball milling. The as-prepared nanoflakes exhibit a narrower thickness distribution of 10-50 nm and high coercivity of 23 kOe. The possible formation mechanism of n...

journal_title：Scientific reports

authors： Zuo WL,Zhao X,Zhao TY,Hu FX,Sun JR,Shen BG

更新日期：2016-05-13 00:00:00

abstract：:Here we investigated the feasibility of using microwave spectroscopy for characterization of normal and breast cancer cell lines cultured in vitro. Healthy non-tumorigenic, MCF-10A and breast cancer, MDA-MB-231, Hs578T, T47D and MCF-7 cell lines were electrically characterized using the open-ended coaxial probe techni...

journal_title：Scientific reports

authors： Hussein M,Awwad F,Jithin D,El Hasasna H,Athamneh K,Iratni R

更新日期：2019-03-18 00:00:00

abstract：:Injured adult tendons do not exhibit optimal healing through a regenerative process, whereas fetal tendons can heal in a regenerative fashion without scar formation. Hence, we compared FFs (mouse fetal fibroblasts) and AFs (mouse adult fibroblasts) as seed cells for the fabrication of scaffold-free engineered tendons....

journal_title：Scientific reports

authors： Tang QM,Chen JL,Shen WL,Yin Z,Liu HH,Fang Z,Heng BC,Ouyang HW,Chen X

更新日期：2014-07-03 00:00:00

abstract：:To examine the association between 18F-fluorodeoxyglucose (18F-FDG) uptake in positron emission tomography/computed tomography (PET/CT) and the response to anti-programmed cell death-1 (PD-1) monoclonal antibody therapy in non-small cell lung cancer (NSCLC) patients, 89 patients with advanced or recurrent NSCLC were r...

journal_title：Scientific reports

authors： Takada K,Toyokawa G,Yoneshima Y,Tanaka K,Okamoto I,Shimokawa M,Wakasu S,Haro A,Osoegawa A,Tagawa T,Oda Y,Nakanishi Y,Mori M

更新日期：2019-09-16 00:00:00

abstract：:Exfoliated monolayer graphene flakes were embedded in a polymer matrix and loaded under axial compression. By monitoring the shifts of the 2D Raman phonons of rectangular flakes of various sizes under load, the critical strain to failure was determined. Prior to loading care was taken for the examined area of the flak...

journal_title：Scientific reports

authors： Androulidakis C,Koukaras EN,Frank O,Tsoukleri G,Sfyris D,Parthenios J,Pugno N,Papagelis K,Novoselov KS,Galiotis C

更新日期：2014-06-12 00:00:00

abstract：:Complex networks are ubiquitous in biological, physical and social sciences. Network robustness research aims at finding a measure to quantify network robustness. A number of Wiener type indices have recently been incorporated as distance-based descriptors of complex networks. Wiener type indices are known to depend b...

journal_title：Scientific reports

authors： Ma J,Shi Y,Wang Z,Yue J

更新日期：2016-01-11 00:00:00

abstract：:This study evaluates the forensic utility of 23 autosomal short tandem repeat markers in 400 samples from the Kuwaiti population, of which four markers (D10S1248, D22S1045, D2S441 and SE33) are reported for the first time for Kuwait. All the markers were shown to exhibit no deviation from Hardy-Weinberg equilibrium, n...

journal_title：Scientific reports

authors： Haidar M,Abbas FA,Alsaleh H,Haddrill PR

更新日期：2021-01-21 00:00:00

abstract：:Acoustic manipulation by an ultrasonic phased array provides an entirely new approach to processes such as coalescence, mixing, separation, and evaporation occurring in the generation of new materials, physical property measurement, the biomedical industry, etc. However, to date, ultrasonic phased arrays have not been...

journal_title：Scientific reports

authors： Watanabe A,Hasegawa K,Abe Y

更新日期：2018-07-05 00:00:00

abstract：:Innate immunity is induced when pathogen-associated molecular patterns (PAMPs) bind host pattern recognition receptors (PRRs). Polyinosinic:polycytidylic acid [poly(I:C)] is a synthetic analogue of viral dsRNA that acts as a PAMP, inducing type I interferons (IFNs) in vertebrates. In the present study, the immunostimu...

journal_title：Scientific reports

authors： Alkie TN,de Jong J,Jenik K,Klinger KM,DeWitte-Orr SJ

更新日期：2019-09-20 00:00:00

abstract：:Galvanic vestibular stimulation (GVS) can be applied to induce the feeling of directional virtual head motion by stimulating the vestibular organs electrically. Conventional studies used a two-pole GVS, in which electrodes are placed behind each ear, or a three-pole GVS, in which an additional electrode is placed on t...

journal_title：Scientific reports

authors： Aoyama K,Iizuka H,Ando H,Maeda T

更新日期：2015-05-11 00:00:00

abstract：:Crosstalk between phytohormone pathways is essential in plant growth, development and stress responses. Brassinosteroids (BRs) and ethylene are both pivotal plant growth regulators, and the interaction between these two phytohormones in the tomato response to salt stress is still unclear. Here, we explored the mechani...

journal_title：Scientific reports

authors： Zhu T,Deng X,Zhou X,Zhu L,Zou L,Li P,Zhang D,Lin H

更新日期：2016-10-14 00:00:00

abstract：:We present new evidence that shows magma mingling can be a key process during highly explosive eruptions. Using fractal analysis of the size distribution of trachybasaltic fragments found on the inner walls of bubbles in trachytic pumices, we show that the more mafic component underwent fracturing during quenching aga...

journal_title：Scientific reports

authors： Paredes-Mariño J,Dobson KJ,Ortenzi G,Kueppers U,Morgavi D,Petrelli M,Hess KU,Laeger K,Porreca M,Pimentel A,Perugini D

更新日期：2017-12-04 00:00:00

abstract：:Hydrogen sulfide is the third and most recently discovered gaseous signaling molecule following nitric oxide and carbon monoxide, playing important roles both in normal physiological conditions and disease progression. The trimethylsulfonium ion (TMS) can result from successive methylation reactions of hydrogen sulfid...

journal_title：Scientific reports

authors： Lajin B,Francesconi KA

更新日期：2016-06-01 00:00:00

abstract：:Large (>10 kb) palindromic sequences are enriched on mammalian sex chromosomes. In mice, these palindromes harbor gene families (≥2 gene copies) expressed exclusively in post-meiotic testicular germ cells, a time when most single-copy sex-linked genes are transcriptionally repressed. This observation led to the hypoth...

journal_title：Scientific reports

authors： Kruger AN,Ellison Q,Brogley MA,Gerlinger ER,Mueller JL

更新日期：2018-06-12 00:00:00

abstract：:Influenza A viruses can infect a wide variety of animal species and, occasionally, humans. Infection occurs through the binding formed by viral surface glycoprotein hemagglutinin and certain types of glycan receptors on host cell membranes. Studies have shown that the α2,3-linked sialic acid motif (SA2,3Gal) in avian,...

journal_title：Scientific reports

authors： Zhao N,Martin BE,Yang CK,Luo F,Wan XF

更新日期：2015-10-28 00:00:00

abstract：:A long-lived reservoir of latently infected T cells prevents antiretroviral therapy from eliminating HIV-1 infection. Furthering our understanding of the dynamics of latency generation and maintenance is therefore vital to improve treatment outcome. Using mathematical models and experiments, we suggest that the death ...

journal_title：Scientific reports

authors： Wodarz D,Levy DN

更新日期：2017-06-19 00:00:00