Identification of the catalytic triad of family S46 exopeptidases, closely related to clan PA endopeptidases.

abstract：:Prospective observation of hemodynamic changes before and after the formation of atherosclerotic stenosis in the carotid artery is difficult. Thus, a vessel surface repairing method was used for retrospective hemodynamic study before and after atherosclerotic stenosis formation in carotid artery. The three-dimensional...

journal_title：Scientific reports

authors： Li X,Sun B,Zhao H,Ge X,Liang F,Li X,Xu J,Liu X

更新日期：2018-04-03 00:00:00

abstract：:Alternatives to antibiotics for improving productivity and maintaining the health of livestock health are urgently needed. The scope of this research was conducted to investigate the effects of two alternatives (Bacillus licheniformis and Saccharomyces cerevisiae) to monensin on growth performance, antioxidant capacit...

journal_title：Scientific reports

authors： Jia P,Cui K,Ma T,Wan F,Wang W,Yang D,Wang Y,Guo B,Zhao L,Diao Q

更新日期：2018-11-12 00:00:00

abstract：:Non-forest ecosystems (predominant in semi-arid and arid regions) contribute significantly to the increasing trend and interannual variation of land carbon uptake over the last three decades, yet the mechanisms are poorly understood. By analysing the flux measurements from 23 ecosystems in Australia, we found the the ...

journal_title：Scientific reports

authors： Li L,Wang YP,Beringer J,Shi H,Cleverly J,Cheng L,Eamus D,Huete A,Hutley L,Lu X,Piao S,Zhang L,Zhang Y,Yu Q

更新日期：2017-09-15 00:00:00

abstract：:Screening and in silico modeling are critical activities for the reduction of experimental costs. They also speed up research notably and strengthen the theoretical framework, thus allowing researchers to numerically quantify the importance of a particular subset of information. For example, in fields such as cancer a...

journal_title：Scientific reports

authors： Blanco JL,Porto-Pazos AB,Pazos A,Fernandez-Lozano C

更新日期：2018-10-24 00:00:00

abstract：:Open-ended evolution (OEE) is relevant to a variety of biological, artificial and technological systems, but has been challenging to reproduce in silico. Most theoretical efforts focus on key aspects of open-ended evolution as it appears in biology. We recast the problem as a more general one in dynamical systems theo...

journal_title：Scientific reports

authors： Adams A,Zenil H,Davies PCW,Walker SI

更新日期：2017-04-20 00:00:00

abstract：:Dengue virus infection is a global threat for which no specific treatment has not been established. Previous reports suggested chrysin and flavanone derivatives were potential flaviviral inhibitors. Here, we reported two halogenated chrysins, abbreviated FV13 and FV14, were highly potent against DENV1-4 and ZIKV infec...

journal_title：Scientific reports

authors： Suroengrit A,Yuttithamnon W,Srivarangkul P,Pankaew S,Kingkaew K,Chavasiri W,Boonyasuppayakorn S

更新日期：2017-10-20 00:00:00

abstract：:Experiments on the Ultimatum Game (UG) repeatedly show that people's behaviour is far from rational. In UG experiments, a subject proposes how to divide a pot and the other can accept or reject the proposal, in which case both lose everything. While rational people would offer and accept the minimum possible amount, i...

journal_title：Scientific reports

authors： Han X,Cao S,Bao JZ,Wang WX,Zhang B,Gao ZY,Sánchez A

更新日期：2018-01-19 00:00:00

abstract：:Discovered in 1813, the conoscopic interference pattern observed due to light propagating through a crystal, kept between crossed polarizers, shows isochromates and isogyres, respectively containing information about the dynamic and geometric phase acquired by the beam. We propose and demonstrate a closed-fringe Fouri...

journal_title：Scientific reports

authors： Samlan CT,Naik DN,Viswanathan NK

更新日期：2016-09-14 00:00:00

abstract：:In day-to-day life, humans usually perceive the location of sound sources as outside their heads. This externalized auditory spatial perception can be reproduced through headphones by recreating the sound pressure generated by the source at the listener's eardrums. This requires the acoustical features of the recordin...

journal_title：Scientific reports

authors： Gil-Carvajal JC,Cubick J,Santurette S,Dau T

更新日期：2016-11-17 00:00:00

abstract：:The pathophysiological mechanism involved in side effects of radiation therapy, and especially the role of the endothelium remains unclear. Previous results showed that plasminogen activator inhibitor-type 1 (PAI-1) contributes to radiation-induced intestinal injury and suggested that this role could be driven by an e...

journal_title：Scientific reports

authors： Rannou E,François A,Toullec A,Guipaud O,Buard V,Tarlet G,Mintet E,Jaillet C,Iruela-Arispe ML,Benderitter M,Sabourin JC,Milliat F

更新日期：2015-10-29 00:00:00

abstract：:Changes in climate and atmospheric CO2 and nitrogen (N) over the last several decades have induced significant effects on forest carbon (C) cycling. However, contributions of individual factors are largely unknown because of the lack of long observational data and the undifferentiating between intrinsic factors and ex...

journal_title：Scientific reports

authors： Wu C,Hember RA,Chen JM,Kurz WA,Price DT,Boisvenue C,Gonsamo A,Ju W

更新日期：2014-03-25 00:00:00

abstract：:CD147/EMMPRIN (extracellular matrix metalloproteinase inducer) plays an important role in tumor progression and a number of studies have suggested that it is an indicator of tumor prognosis. This current meta-analysis systematically reevaluated the predictive potential of CD147/EMMPRIN in various cancers. We searched ...

journal_title：Scientific reports

authors： Xin X,Zeng X,Gu H,Li M,Tan H,Jin Z,Hua T,Shi R,Wang H

更新日期：2016-09-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Tsuchiya K,Suzuki Y,Yoshimura K,Yasui H,Karayama M,Hozumi H,Furuhashi K,Enomoto N,Fujisawa T,Nakamura Y,Inui N,Yokomura K,Suda T

更新日期：2020-02-19 00:00:00

abstract：:Bacterial proteins exported to the cell surface play key cellular functions. However, despite the interest to study the localisation of surface proteins such as adhesins, transporters or hydrolases, monitoring their dynamics in live imaging remains challenging, due to the limited availability of fluorescent probes rem...

journal_title：Scientific reports

authors： Chekli Y,Peron-Cane C,Dell'Arciprete D,Allemand JF,Li C,Ghigo JM,Gautier A,Lebreton A,Desprat N,Beloin C

更新日期：2020-09-25 00:00:00

abstract：:Methylation of histone H3 lysine 4 (H3K4) is catalyzed by the multi-component COMPASS or COMPASS-like complex, which is highly conserved from yeast to human, and plays essential roles in gene expression and transcription, cell cycle progression, and DNA repair. Here we present a cryo-EM map of the complete S. cerevisi...

journal_title：Scientific reports

authors： Wang Y,Ding Z,Liu X,Bao Y,Huang M,Wong CCL,Hong X,Cong Y

更新日期：2018-11-27 00:00:00

abstract：:Tumor tissue mutational burden (TMB) has emerged as a promising predictive biomarker for immune checkpoint therapy. Measuring TMB from circulating tumor DNA (ctDNA) found in plasma is attractive in tissue-constrained indications. We compared the performance of two plasma-based commercial TMB assays including the effec...

journal_title：Scientific reports

authors： Qiu P,Poehlein CH,Marton MJ,Laterza OF,Levitan D

更新日期：2019-01-14 00:00:00

abstract：:The transfer entropy is a well-established measure of information flow, which quantifies directed influence between two stochastic time series and has been shown to be useful in a variety fields of science. Here we introduce the transfer entropy of the backward time series called the backward transfer entropy, and sho...

journal_title：Scientific reports

authors： Ito S

更新日期：2016-11-11 00:00:00

abstract：:Apparently mundane, amorphous nanostructures of carbon have optical properties which are as exotic as their crystalline counterparts. In this work we demonstrate a simple and inexpensive mechano-chemical method to prepare bulk quantities of self-passivated, amorphous carbon dots. Like the graphene quantum dots, the wa...

journal_title：Scientific reports

authors： Siddique AB,Pramanick AK,Chatterjee S,Ray M

更新日期：2018-06-27 00:00:00

abstract：:Seeds of tomato were magnetoprimed at 100 mT for 30 min followed by imbibition for 12 and 24 h, respectively, at 20 °C, to examine the biochemical and molecular changes involved in homeostasis of hydrogen peroxide (H2O2) and its signaling associated with hormone interactions for promoting vigor. The relative transcrip...

journal_title：Scientific reports

authors： Anand A,Kumari A,Thakur M,Koul A

更新日期：2019-06-19 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xie J,Wang M,Cheng A,Zhao XX,Liu M,Zhu D,Chen S,Jia R,Yang Q,Wu Y,Zhang S,Liu Y,Yu Y,Zhang L,Sun K,Chen X

更新日期：2020-03-24 00:00:00

abstract：:Isolated lung perfusion (ILP) is an ideal model to study treatment effects on a variety of pathologies. As published research mostly relies on rejected donor lungs or animal organs, this study investigates the use of surgically resected human lobes as an alternative and novel model for personalized experimental resear...

journal_title：Scientific reports

authors： Slama A,Raber C,Hedderich C,Stockhammer P,Hegedüs B,Koch A,Theegarten D,Ploenes T,Aigner C

更新日期：2019-08-21 00:00:00

abstract：:Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water deficit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water deficit and ABA induce expression of some RD22-like proteins. This study aimed to evaluate the effect of water deficit and exogenous ABA...

journal_title：Scientific reports

authors： Phillips K,Ludidi N

更新日期：2017-08-18 00:00:00

abstract：:Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attri...

journal_title：Scientific reports

authors： Luan P,Xie M,Liu D,Fu X,Jing L

更新日期：2014-08-26 00:00:00

abstract：:CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions. In this study we examined the role of...

journal_title：Scientific reports

authors： Alisson-Silva F,Mantuano NR,Lopes AL,Vasconcelos-Dos-Santos A,Vale AM,Costa MM,Cannon JL,Oliveira AC,Todeschini AR

更新日期：2019-06-13 00:00:00

abstract：:Spontaneous activity found in neural networks usually results in a reduction of computational performance. As a consequence, artificial neural networks are often operated at the edge of chaos, where the network is stable yet highly susceptible to input information. Surprisingly, regular spontaneous dynamics in Neural ...

journal_title：Scientific reports

authors： Marquez BA,Larger L,Jacquot M,Chembo YK,Brunner D

更新日期：2018-02-20 00:00:00

abstract：:The C1q complement/TNF-related protein superfamily (CTRPs) displays differential effects on the regulation of metabolic homeostasis, governing cardiovascular function. However, whether and how they may serve as predictor/pro-diagnosis factors for assessing the risks of coronary artery disease (CAD) remains controversi...

journal_title：Scientific reports

authors： Zhang Y,Liu C,Liu J,Guo R,Yan Z,Liu W,Lau WB,Jiao X,Cao J,Xu K,Jia Y,Ma X,Wang Y

更新日期：2020-01-21 00:00:00

abstract：:Targeted antineoplastic agents show great promise in the treatment of cancer, having the ability to impart cytotoxicity only to specific tumor types. However, these therapies do not experience uniform uptake throughout tumors, leading to sub-lethal cell killing that can impart treatment resistance, and cause problemat...

journal_title：Scientific reports

authors： Klein OJ,Yuan H,Nowell NH,Kaittanis C,Josephson L,Evans CL

更新日期：2017-10-17 00:00:00

abstract：:In this work, we demonstrate an innovative approach, combing a novel active screen plasma (ASP) technique with green chemical synthesis, for a direct fabrication of uniform Pt nanowire arrays on large-area supports. The ASP treatment enables in-situ N-doping and surface modification to the support surface, significant...

journal_title：Scientific reports

authors： Du S,Lin K,Malladi SK,Lu Y,Sun S,Xu Q,Steinberger-Wilckens R,Dong H

更新日期：2014-09-22 00:00:00

abstract：:The design of active and stable semiconducting composites with enhanced photoresponse from visible light to near infrared (NIR) is a key to improve solar energy harvesting for photolysis of water in photoelectrochemical cell. In this study, we prepared earth abundant semiconducting composites consisting of iron pyrite...

journal_title：Scientific reports

authors： Wang DY,Li CH,Li SS,Kuo TR,Tsai CM,Chen TR,Wang YC,Chen CW,Chen CC

更新日期：2016-02-08 00:00:00

abstract：:TP53 mutation (i.e., loss of normal-p53) may evoke epithelial-mesenchymal transition (EMT), which was previously attributed to loss of certain miRNAs. However, not all epithelial cells undergo EMT upon TP53 mutation, and the p53-miRNA axis may not fully explain p53 function in epithelial integrity. We here show two mo...

journal_title：Scientific reports

authors： Oikawa T,Otsuka Y,Onodera Y,Horikawa M,Handa H,Hashimoto S,Suzuki Y,Sabe H

更新日期：2018-01-25 00:00:00