Understanding and simulating the material behavior during multi-particle irradiations.

abstract：:A coherent anti-Stokes Raman scattering (CARS) rigid endoscope was developed to visualize peripheral nerves without labeling for nerve-sparing endoscopic surgery. The developed CARS endoscope had a problem with low imaging speed, i.e. low imaging rate. In this study, we demonstrate that noise reduction with deep learn...

journal_title：Scientific reports

authors： Yamato N,Niioka H,Miyake J,Hashimoto M

更新日期：2020-09-16 00:00:00

abstract：:Triassic archosaurs and stem-archosaurs show a remarkable disparity in their ankle and pelvis morphologies. However, the implications of these different morphologies for specific functions are still poorly understood. Here, we present the first quantitative analysis into the locomotor abilities of a stem-archosaur app...

journal_title：Scientific reports

authors： Demuth OE,Rayfield EJ,Hutchinson JR

更新日期：2020-09-21 00:00:00

abstract：:In many vertebrates, acoustic cues to body size are encoded in resonance frequencies of the vocal tract ("formants"), rather than in the rate of tissue vibration in the sound source ("pitch"). Anatomical constraints on the vocal tract's size render formants honest cues to size in many bird and mammal species, but it i...

journal_title：Scientific reports

authors： Reber SA,Janisch J,Torregrosa K,Darlington J,Vliet KA,Fitch WT

更新日期：2017-05-12 00:00:00

abstract：:Despite the increasing number of studies conducted recently to evaluate the association between HPV infections and the risk of prostate cancer, the results remain inconclusive. Furthermore, the prevalence and distribution of overall and individual HPV types worldwide in prostate cancer has not been reported until now....

journal_title：Scientific reports

authors： Yang L,Xie S,Feng X,Chen Y,Zheng T,Dai M,Zhou CK,Hu Z,Li N,Hang D

更新日期：2015-10-06 00:00:00

abstract：:Acute pancreatitis (AP) is a complicated disease without specific drug therapy. The cofactor nicotinamide adenine dinucleotide (NAD+) is an important regulator of cellular metabolism and homeostasis. However, it remains unclear whether modulation of NAD+ levels has an impact on caerulein-induced AP. Therefore, in this...

journal_title：Scientific reports

authors： Shen A,Kim HJ,Oh GS,Lee SB,Lee SH,Pandit A,Khadka D,Choe SK,Kwak SC,Yang SH,Cho EY,Kim HS,Kim H,Park R,Kwak TH,So HS

更新日期：2017-06-07 00:00:00

abstract：:Fatigue is a very common and costly symptom associated with various diseases and disorders. Nonetheless, understanding the pathobiology and developing of therapies for fatigue have been difficult, partly because of a lack of consensus on the measures to phenotype this behavior, both in clinical settings and in animal ...

journal_title：Scientific reports

authors： Wolff BS,Raheem SA,Saligan LN

更新日期：2018-09-24 00:00:00

abstract：:Tumor aggressiveness is usually associated with metastasis. MDA-MB 231, a triple-negative breast cancer (TNBC), is an aggressive type of breast cancer and associated with early metastasis. The Rho/ROCK pathway is a key regulator of cell motility involving cytoskeleton regulation through stabilization of actin filament...

journal_title：Scientific reports

authors： Guerra FS,Oliveira RG,Fraga CAM,Mermelstein CDS,Fernandes PD

更新日期：2017-10-20 00:00:00

abstract：:The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically, we use sgRNA-mediated CRISPR/Cas9 to target the open reading fr...

journal_title：Scientific reports

authors： You Y,Ramachandra SG,Jin T

更新日期：2020-09-08 00:00:00

abstract：:Although previous findings identified an association between C-reactive protein (CRP) levels, and impaired cognitive functions in patients with schizophrenia (SZ), little is currently known about the relationship between inflammation, cognition, and sex in SZ. The current study aimed to explore the association between...

journal_title：Scientific reports

authors： Dal Santo F,González-Blanco L,García-Álvarez L,de la Fuente-Tomás L,Velasco Á,Álvarez-Vázquez CM,Martínez-Cao C,Sáiz PA,García-Portilla MP,Bobes J

更新日期：2020-09-29 00:00:00

abstract：:Although the anxiolytic-like effects of Xiaoyaosan, a Chinese herbal formula, have been described in many previous studies, its underlying mechanism remains undefined. The cytokine tumour necrosis factor-α (TNF-α) and its closely associated janus kinase 2 (JAK2)-signal transducer and activator of transcription (STAT3)...

journal_title：Scientific reports

authors： Li XJ,Ma QY,Jiang YM,Bai XH,Yan ZY,Liu Q,Pan QX,Liu YY,Chen JX

更新日期：2017-03-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Lee DB,Kim JM,Seok JH,Lee JH,Jo JD,Mun JY,Conrad C,Coe J,Nelson G,Hogue B,White TA,Zatsepin N,Weierstall U,Barty A,Chapman H,Fromme P,Spence J,Chung MS,Oh CH,Kim KH

更新日期：2018-04-17 00:00:00

abstract：:Balloon whisk-like and flower-like SiOx tubes with well-dispersed Sn and joining countless SiOx loops together induce intense luminescence characteristics in substrate materials. Our synthetic technique called "direct substrate growth" is based on pre-contamination of the surroundings without the intended catalyst and...

journal_title：Scientific reports

authors： Jin C,Hwang SJ,Cho MS,Choi SW,Na HG,Park S,Park S,Noh Y,Jeong H,Lee D

更新日期：2016-08-01 00:00:00

abstract：:Temporal fluctuation of neural activity in the brain has an important function in optimal information processing. Spontaneous activity is a source of such fluctuation. The distribution of excitatory postsynaptic potentials (EPSPs) between cortical pyramidal neurons can follow a log-normal distribution. Recent studies ...

journal_title：Scientific reports

authors： Nobukawa S,Nishimura H,Yamanishi T

更新日期：2019-09-04 00:00:00

abstract：:Polymers have appealing optical, biochemical, and mechanical qualities, including broadband transparency, ease of functionalization, and biocompatibility. However, their low refractive indices have precluded wavelength-scale optical confinement and nanophotonic applications in polymers. Here, we introduce a suspended ...

journal_title：Scientific reports

authors： Gan X,Clevenson H,Tsai CC,Li L,Englund D

更新日期：2013-01-01 00:00:00

abstract：:In many human cancers, including hepatocellular carcinoma (HCC), high density of infiltrating tumor-associated macrophages (TAM) is associated with poor prognosis. Most TAMs express a M2 phenotype subsequently supporting tumor growth. How tumor cells polarize these TAMs to a pro-tumor M2 phenotype is still poorly unde...

journal_title：Scientific reports

authors： Shiau DJ,Kuo WT,Davuluri GVN,Shieh CC,Tsai PJ,Chen CC,Lin YS,Wu YZ,Hsiao YP,Chang CP

更新日期：2020-08-12 00:00:00

abstract：:2-(1-Undecyloxy)-1-ethanol, monochamol, is a male-produced aggregation pheromone of the Monochamus species, which are efficient vectors of the pine wood nematode (PWN), Bursaphelenchus xylophilus, which cause devastating damage to pines worldwide. The nematicidal activity of synthetic monochamol and its homologues (RO...

journal_title：Scientific reports

authors： Kim J,Lee SM,Park CG

更新日期：2016-07-11 00:00:00

abstract：:When sliding our fingertip against a textured surface, complex vibrations are produced in the skin. It is increasingly recognised that the neural transduction and processing of these vibrations plays an important role in the dynamic tactile perception of textures. The aim of the present study was to develop a novel me...

journal_title：Scientific reports

authors： Moungou A,Thonnard JL,Mouraux A

更新日期：2016-02-08 00:00:00

abstract：:Type IV secretion systems are multiprotein complexes that mediate the translocation of macromolecules across the bacterial cell envelope. In Helicobacter pylori a type IV secretion system encoded by the cag pathogenicity island encodes 27 proteins and most are essential for virulence. We here present the identificatio...

journal_title：Scientific reports

authors： Arya T,Oudouhou F,Casu B,Bessette B,Sygusch J,Baron C

更新日期：2019-04-24 00:00:00

abstract：:Glaulactams A-C (1-3), which possess a novel skeleton, as well as the known compound daphmanidin B (4), were isolated from the leaves of Daphniphyllum glaucescens and separated using ion-exchange chromatography aided by NMR fingerprinting. Their structures, including their absolute configurations, were elucidated by s...

journal_title：Scientific reports

authors： Chao CH,Cheng JC,Gonçalves TP,Huang KW,Lin CC,Huang HC,Hwang SY,Wu YC

更新日期：2018-10-18 00:00:00

abstract：:Electrochemically generated bactericidal compounds have been shown to eradicate bacterial lawn biofilms through electroceutical treatment. However, the ultrastructure of biofilms exposed to these species has not been studied. Moreover, it is unknown if the efficacy of electroceutical treatment extends to antibiotic-re...

journal_title：Scientific reports

authors： Lochab V,Jones TH,Dusane DH,Peters CW,Stoodley P,Wozniak DJ,Subramaniam VV,Prakash S

更新日期：2020-06-18 00:00:00

abstract：:Porous materials display enhanced scattering mechanisms that greatly influence their transport properties. Metal-assisted chemical etching (MACE) enables fabrication of porous silicon nanowires starting from a doped Si wafer by using a metal template that catalyzes the etching process. Here, we report on the low therm...

journal_title：Scientific reports

authors： Ferrando-Villalba P,D'Ortenzi L,Dalkiranis GG,Cara E,Lopeandia AF,Abad L,Rurali R,Cartoixà X,De Leo N,Saghi Z,Jacob M,Gambacorti N,Boarino L,Rodríguez-Viejo J

更新日期：2018-08-24 00:00:00

abstract：:Using analytical expressions for the magnetization textures of thin submicron-sized magnetic cylinders in vortex state, we derive closed-form algebraic expressions for the ensuing small-angle neutron scattering (SANS) cross sections. Specifically, for the perpendicular and parallel scattering geometries, we have compu...

journal_title：Scientific reports

authors： Metlov KL,Michels A

更新日期：2016-04-26 00:00:00

abstract：:Proton-sensing ovarian cancer G-protein coupled receptor (OGR1) plays an important role in pH homeostasis. Acidosis occurs at sites of intestinal inflammation and can induce endoplasmic reticulum (ER) stress and the unfolded protein response (UPR), an evolutionary mechanism that enables cells to cope with stressful co...

journal_title：Scientific reports

authors： Maeyashiki C,Melhem H,Hering L,Baebler K,Cosin-Roger J,Schefer F,Weder B,Hausmann M,Scharl M,Rogler G,de Vallière C,Ruiz PA

更新日期：2020-01-29 00:00:00

abstract：:This study aimed to investigate the predictive efficacy of positron emission tomography/computed tomography (PET/CT) and magnetic resonance imaging (MRI) for the pathological response of advanced breast cancer to neoadjuvant chemotherapy (NAC). The breast PET/MRI image deep learning model was introduced and compared w...

journal_title：Scientific reports

authors： Choi JH,Kim HA,Kim W,Lim I,Lee I,Byun BH,Noh WC,Seong MK,Lee SS,Kim BI,Choi CW,Lim SM,Woo SK

更新日期：2020-12-03 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a tinnitus treatment option. Promising results have been obtained by consecutive stimulation of lateral frontal and auditory brain regions. We investigated a combined stimulation paradigm targeting the anterior cingulate cortex (ACC) with double ...

journal_title：Scientific reports

authors： Kreuzer PM,Lehner A,Schlee W,Vielsmeier V,Schecklmann M,Poeppl TB,Landgrebe M,Rupprecht R,Langguth B

更新日期：2015-12-15 00:00:00

abstract：:In vitro recapitulation of an organotypic stromal environment, enabling efficient angiogenesis, is crucial to investigate and possibly improve vascularization in regenerative medicine. Our study aims at engineering the complexity of a vascular milieu including multiple cell-types, a stromal extracellular matrix (ECM),...

journal_title：Scientific reports

authors： Cerino G,Gaudiello E,Muraro MG,Eckstein F,Martin I,Scherberich A,Marsano A

更新日期：2017-10-27 00:00:00

abstract：:Cardiorenal syndrome is defined by primary heart failure conditions influencing or leading to renal injury or dysfunction. Dilated cardiomyopathy (DCM) is a major co-existing form of heart failure (HF) with renal diseases. Myocardin (MYOCD), a cardiac-specific co-activator of serum response factor (SRF), is increased ...

journal_title：Scientific reports

authors： Mittal A,Rana S,Sharma R,Kumar A,Prasad R,Raut SK,Sarkar S,Saikia UN,Bahl A,Dhandapany PS,Khullar M

更新日期：2019-04-10 00:00:00

abstract：:Psychopathy is a personality disorder characterised by atypical moral behaviour likely rooted in atypical affective/motivational processing, as opposed to an inability to judge the wrongness of an action. Guilt is a moral emotion believed to play a crucial role in adherence to moral and social norms, but the mechanism...

journal_title：Scientific reports

authors： Seara-Cardoso A,Sebastian CL,McCrory E,Foulkes L,Buon M,Roiser JP,Viding E

更新日期：2016-11-03 00:00:00

abstract：:In this paper, we evaluated the power of microbiome measures taken at three time points over the growth test period (weaning, 15 and 22 weeks) to foretell growth and carcass traits in 1039 individuals of a line of crossbred pigs. We measured prediction accuracy as the correlation between actual and predicted phenotype...

journal_title：Scientific reports

authors： Maltecca C,Lu D,Schillebeeckx C,McNulty NP,Schwab C,Shull C,Tiezzi F

更新日期：2019-04-25 00:00:00

abstract：:Water-soluble protein content (WSPC) is a critical factor in both soybean protein quality and functionality. However, the underlying genetic determinants are unclear. Here, we used 219 soybean accessions and 152 recombinant inbred lines genotyped with high-density markers and phenotyped in multi-environments to dissec...

journal_title：Scientific reports

authors： Zhang D,Lü H,Chu S,Zhang H,Zhang H,Yang Y,Li H,Yu D

更新日期：2017-07-11 00:00:00