Use of Zebrafish Larvae as a Multi-Endpoint Platform to Characterize the Toxicity Profile of Silica Nanoparticles.

abstract：:Gastroenteritis is common among children. Campylobacter jejuni is one of the main causative bacterial pathogens, together with Shigella, Salmonella and invasive Escherichia coli. Campylobacteriosis is a zoonotic, usually self-limited disease that does not always require antibiotic treatment. In cases of protracted dia...

journal_title：Scientific reports

authors： Sakran W,Hexner-Erlichman Z,Spiegel R,Batheesh H,Halevy R,Koren A

更新日期：2020-04-02 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Martin T,Dauvilliers Y,Koumar OC,Bouet V,Freret T,Besnard S,Dauphin F,Bessot N

更新日期：2020-04-02 00:00:00

abstract：:Inflammation is considered as a major contributor to brain injury following cerebral ischemia. The therapeutic potential of both MLC601/MLC901, which are herbal extract preparations derived from Chinese Medicine, has been reported both in advanced stroke clinical trials and also in animal and cellular models. The aim ...

journal_title：Scientific reports

authors： Widmann C,Gandin C,Petit-Paitel A,Lazdunski M,Heurteaux C

更新日期：2018-12-24 00:00:00

abstract：:The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers. We thus compared the levels of biliary and serum MIC-1 and conventional tumour markers between 23 biliary tract cancer (BTC) patients (malignant group) and 29 benign biliary disease patients (benign grou...

journal_title：Scientific reports

authors： Sugimoto M,Takagi T,Konno N,Suzuki R,Asama H,Watanabe K,Nakamura J,Waragai Y,Kikuchi H,Takasumi M,Sato Y,Hikichi T,Ohira H

更新日期：2017-08-23 00:00:00

abstract：:Performance of a recently developed test for association between multivariate phenotypes and sets of genetic variants (MURAT) is demonstrated using measures of bone mineral density (BMD). By combining individual-level whole genome sequenced data from the UK10K study, and imputed genome-wide genetic data on individuals...

journal_title：Scientific reports

authors： Sun J,Oualkacha K,Forgetta V,Zheng HF,Richards JB,Evans DS,Orwoll E,Greenwood CMT

更新日期：2018-01-09 00:00:00

abstract：:Probing the cellular structure of in vivo biological tissue is a fundamental problem in biomedical imaging and medical science. This work introduces an approach for analyzing diffusion magnetic resonance imaging data acquired by the novel tensor-valued encoding technique for characterizing tissue microstructure. Our a...

journal_title：Scientific reports

authors： Ning L,Szczepankiewicz F,Nilsson M,Rathi Y,Westin CF

更新日期：2021-01-08 00:00:00

abstract：:In this study we present an image analysis methodology capable of quantifying morphological changes in tissue collagen fibril organization caused by pathological conditions. Texture analysis based on first-order statistics (FOS) and second-order statistics such as gray level co-occurrence matrix (GLCM) was explored to...

journal_title：Scientific reports

authors： Mostaço-Guidolin LB,Ko AC,Wang F,Xiang B,Hewko M,Tian G,Major A,Shiomi M,Sowa MG

更新日期：2013-01-01 00:00:00

abstract：:The regional and international trade of live animals facilitates the movement, spillover, and emergence of zoonotic and epizootic pathogens around the world. Detecting pathogens in trade is critical for preventing their continued movement and introduction, but screening a sufficient fraction to ensure rare infections ...

journal_title：Scientific reports

authors： Brunner JL

更新日期：2020-06-24 00:00:00

abstract：:Exchange bias (EB) of magnetic nanoparticles (MNPs) in the nanoscale regime has been extensively studied by researchers, which have opened up a novel approach in tuning the magnetic anisotropy properties of magnetic nanoparticles (MNPs) in prospective application of biomedical research such as magnetic hyperthermia. I...

journal_title：Scientific reports

authors： Tsopoe SP,Borgohain C,Fopase R,Pandey LM,Borah JP

更新日期：2020-10-29 00:00:00

abstract：:The development of selective visual attention is critical for effectively engaging with an ever-changing world. Its optimal deployment depends upon interactions between neural, motor, and sensory systems across multiple timescales and neurocognitive loci. Previous work illustrates the spatio-temporal dynamics of these...

journal_title：Scientific reports

authors： Stallworthy IC,Sifre R,Berry D,Lasch C,Smith TJ,Elison JT

更新日期：2020-10-14 00:00:00

abstract：:Hyperspectral imaging technology is playing an increasingly important role in the fields of food analysis, medicine and biotechnology. To improve the speed of operation and increase the light throughput in a compact equipment structure, a Fourier transform hyperspectral imaging system based on a single-pixel technique...

journal_title：Scientific reports

authors： Jin S,Hui W,Wang Y,Huang K,Shi Q,Ying C,Liu D,Ye Q,Zhou W,Tian J

更新日期：2017-03-24 00:00:00

abstract：:Clinicians often hesitate prescribing corticosteroids to treat corticosteroid-responsive conditions in sickle cell disease (SCD) patients because their use can be associated with complications (increased hospital readmission, rebound pain, strokes, avascular necrosis, acute chest syndrome). Consequently, SCD patients ...

journal_title：Scientific reports

authors： Almeida LEF,Damsker JM,Albani S,Afsar N,Kamimura S,Pratt D,Kleiner DE,Quezado M,Gordish-Dressman H,Quezado ZMN

更新日期：2018-04-17 00:00:00

abstract：:The role of orbital differentiation on the emergence of superconductivity in the Fe-based superconductors remains an open question to the scientific community. In this investigation, we employ a suitable microscopic spin probe technique, namely Electron Spin Resonance (ESR), to investigate this issue on selected chemi...

journal_title：Scientific reports

authors： Rosa PF,Adriano C,Garitezi TM,Grant T,Fisk Z,Urbano RR,Pagliuso PG

更新日期：2014-10-08 00:00:00

abstract：:A series of β-NaLuF4 crystals were synthesized via a hydrothermal method. Hexagonal phase microdisks, microprisms, and microtubes were achieved by simply changing the amount of citric acid in the initial reaction solution. Pure red upconversion (UC) luminescence can be observed in β-NaLuF4:Yb(3+), Tm(3+), Er(3+) and L...

journal_title：Scientific reports

authors： Lin H,Xu D,Li A,Teng D,Yang S,Zhang Y

更新日期：2016-06-16 00:00:00

abstract：:Although giant proximity effect (GPE) can shed important information on understanding superconducting pairing mechanisms and superconducting electronics, reports on the GPE are few because the fabrication of the junctions with GPE is technologically difficult. Here, we report a GPE in the single-crystalline MgB2 bilay...

journal_title：Scientific reports

authors： Jung SG,Pham D,Park TH,Choi HY,Seo JW,Kang WN,Park T

更新日期：2019-03-01 00:00:00

abstract：:The construction of three-dimensional graphene aerogels (GAs) is of great importance owing to their outstanding properties for various applications. Up to now, the combination of ultralow weight and super mechanical strength for GA remains a great challenge. Here we demonstrate the fabrication of cellular GAs by a fac...

journal_title：Scientific reports

authors： Zhang B,Zhang J,Sang X,Liu C,Luo T,Peng L,Han B,Tan X,Ma X,Wang D,Zhao N

更新日期：2016-05-12 00:00:00

abstract：:The transcriptional regulator JDP2 (Jun dimerization protein 2) has been identified as a prognostic marker for patients to develop heart failure after myocardial infarction. We now performed in vivo studies on JDP2-overexpressing mice, to clarify the impact of JDP2 on heart failure progression. Therefore, during birth...

journal_title：Scientific reports

authors： Heger J,Bornbaum J,Würfel A,Hill C,Brockmann N,Gáspár R,Pálóczi J,Varga ZV,Sárközy M,Bencsik P,Csont T,Török S,Kojonazarov B,Schermuly RT,Böngler K,Parahuleva M,Ferdinandy P,Schulz R,Euler G

更新日期：2018-05-16 00:00:00

abstract：:The iron binding capacities (IBC) of fulvic acid (FA) and humic acid (HA) were determined in the salinity range from 5 to 40. The results indicated that IBC decreased while salinity increased. In addition, dissolved iron (dFe), FA and HA were also determined along the Yangtze River estuary's increasing salinity gradie...

journal_title：Scientific reports

authors： Yang R,Su H,Qu S,Wang X

更新日期：2017-05-03 00:00:00

abstract：:Carbon nanotubes exhibit mechanical properties ideally suited for reinforced structural composites and surface area and conductivity attractive for electrochemical capacitors. Here we demonstrate the multifunctional synergy between these properties in a composite material exhibiting simultaneous mechanical and energy ...

journal_title：Scientific reports

authors： Muralidharan N,Teblum E,Westover AS,Schauben D,Itzhak A,Muallem M,Nessim GD,Pint CL

更新日期：2018-12-05 00:00:00

abstract：:The proportion of women who experience a depressive state after delivery differs between primiparas and multiparas, so it is important to clarify the different factors related to depression between the two groups. In this study, we confirmed the differences in depressive states, the perinatal period, and social suppor...

journal_title：Scientific reports

authors： Nakamura Y,Okada T,Morikawa M,Yamauchi A,Sato M,Ando M,Ozaki N

更新日期：2020-10-13 00:00:00

abstract：:Dementia is a neurocognitive disorder characterized by a progressive memory loss and impairment in cognitive and functional abilities. Autophagy and mitophagy are two important cellular processes by which the damaged intracellular components are degraded by lysosomes. To investigate the contribution of autophagy and m...

journal_title：Scientific reports

authors： Castellazzi M,Patergnani S,Donadio M,Giorgi C,Bonora M,Bosi C,Brombo G,Pugliatti M,Seripa D,Zuliani G,Pinton P

更新日期：2019-12-27 00:00:00

abstract：:Zika virus (ZIKV) can cause various diseases in offspring after congenital infection. The purpose of this study was to identify disease phenotypes in pups exposed to ZIKV in utero. Female interferon-α/β, -γ receptor knockout mice (AG129) were infected intraperitoneally with ZIKV 7.5 days' post coitus (dpc). Viral RNA,...

journal_title：Scientific reports

authors： Julander JG,Siddharthan V,Park AH,Preston E,Mathur P,Bertolio M,Wang H,Zukor K,Van Wettere AJ,Sinex DG,Morrey JD

更新日期：2018-06-20 00:00:00

abstract：:Breast cancer (BC) has a higher incidence in young Lebanese woman as compared to the West. We assessed the microRNA (miRNA) microarray profile of tissues derived from Lebanese patients with early BC and performed mRNA-miRNA integration analysis. 173 miRNAs were significantly dysregulated in 45 BC versus 17 normal adja...

journal_title：Scientific reports

authors： Nassar FJ,Talhouk R,Zgheib NK,Tfayli A,El Sabban M,El Saghir NS,Boulos F,Jabbour MN,Chalala C,Boustany RM,Kadara H,Zhang Z,Zheng Y,Joyce B,Hou L,Bazarbachi A,Calin G,Nasr R

更新日期：2017-12-04 00:00:00

abstract：:Recently, development of Adeno-associated virus (AAV) vectors has been focusing on expanding the genetic diversity of vectors from existing sequences via directed evolution or epitope remapping. Apart from intelligent design, AAV isolation from natural sources remains an important source of new AAVs with unique biolog...

journal_title：Scientific reports

authors： Bello A,Chand A,Aviles J,Soule G,Auricchio A,Kobinger GP

更新日期：2014-10-22 00:00:00

abstract：:Charge separation is a critical process for achieving high efficiencies in organic photovoltaic cells. The initial tightly bound excitonic electron-hole pair has to dissociate fast enough in order to avoid photocurrent generation and thus power conversion efficiency loss via geminate recombination. Such process takes ...

journal_title：Scientific reports

authors： Oviedo-Casado S,Urbina A,Prior J

更新日期：2017-06-27 00:00:00

abstract：:The F1F0-ATP synthase, an enzyme complex, is mainly located on the mitochondrial inner membrane or sometimes cytomembrane to generate or hydrolyze ATP, play a role in cell proliferation. This study focused on the role of F1F0-ATP synthase in keratinocyte differentiation, and its relationship with intracellular and ext...

journal_title：Scientific reports

authors： Xiaoyun X,Chaofei H,Weiqi Z,Chen C,Lixia L,Queping L,Cong P,Shuang Z,Juan S,Xiang C

更新日期：2017-02-17 00:00:00

abstract：:CHF5633 is a novel synthetic clinical pulmonary surfactant preparation composed by two phospholipid species, dipalmitoyl phosphatidylcholine (DPPC) and palmitoyloleoyl phosphatidylglycerol (POPG), and synthetic analogues of the hydrophobic surfactant proteins SP-B and SP-C. In this study, the interfacial properties of...

journal_title：Scientific reports

authors： Echaide M,Autilio C,López-Rodríguez E,Cruz A,Pérez-Gil J

更新日期：2020-01-28 00:00:00

abstract：:Untreated pathological cardiac hypertrophy, which can be caused by sustained systemic hypertension, may lead to heart failure. In the present study, we investigated whether AS-1 had attenuating effects on hypertension-induced cardiac hypertrophy, and whether this process was mediated by the regulation of miRNA-143. To...

journal_title：Scientific reports

authors： Song J,Xie Q,Wang L,Lu Y,Liu P,Yang P,Chen R,Shao C,Qiao C,Wang Z,Yan J

更新日期：2019-04-23 00:00:00

abstract：:Allergic asthma and obesity are major public health problems in the world. Recent Meta-analysis studies implicated a positive relationship between serum leptin, which is elevated in obese individuals, and the risk of asthma. However, it is not well understood how obesity-associated elevation of leptin increases the ri...

journal_title：Scientific reports

authors： Zheng H,Wu D,Wu X,Zhang X,Zhou Q,Luo Y,Yang X,Chock CJ,Liu M,Yang XO

更新日期：2018-06-11 00:00:00

abstract：:Cell-free DNA is present in different biological fluids and when released by tumor cells may contribute to pro-tumor events such as malignant transformation of cells adjacent to the tumor and metastasis. Thus, this study analyzed the effect of tumor cell-free DNA, isolated from the blood of prostate cancer patients, o...

journal_title：Scientific reports

authors： Souza AG,Bastos VAF,Fujimura PT,Ferreira ICC,Leal LF,da Silva LS,Laus AC,Reis RM,Martins MM,Santos PS,Corrêa NCR,Marangoni K,Thomé CH,Colli LM,Goulart LR,Goulart VA

更新日期：2020-12-10 00:00:00