Tissue remodeling after ocular surface reconstruction with denuded amniotic membrane.

abstract：:High fat diet (HFD)-induced metabolic disorders may lead to emotional disorders. This study aimed to explore the effect of simvastatin (SMV) and bezafibrate (BZ) on improving HFD-induced emotional changes, and tried to identify their different mechanisms. The intraperitoneal glucose tolerance test (IPGTT) was used to ...

journal_title：Scientific reports

authors： Wang H,Zhou J,Liu QZ,Wang LL,Shang J

更新日期：2017-05-24 00:00:00

abstract：:Large-scale molecular epidemiologic studies of Plasmodium falciparum parasites have provided insights into parasite biology and transmission, can identify the spread of drug resistance, and are useful in assessing vaccine targets. The polyclonal nature infections in high transmission settings is problematic for tradit...

journal_title：Scientific reports

authors： Levitt B,Obala A,Langdon S,Corcoran D,O'Meara WP,Taylor SM

更新日期：2017-01-24 00:00:00

abstract：:Cardiac tissue engineering using biomaterials with or without combination of stem cell therapy offers a new option for repairing infarcted heart. However, the bioactivity of biomaterials remains to be optimized because currently available biomaterials do not mimic the biochemical components as well as the structural p...

journal_title：Scientific reports

authors： Wan L,Chen Y,Wang Z,Wang W,Schmull S,Dong J,Xue S,Imboden H,Li J

更新日期：2017-01-04 00:00:00

abstract：:The electrohydrodynamic (EHD) jet spraying process is a good method for making quantum dot (QD) layers in light-emitting diodes (LEDs). However, controlling the morphology and large-scale fabrication of the QD layers are critical for realizing all-solution-processed QD-LEDs with high performance. Three spraying techni...

journal_title：Scientific reports

authors： Nguyen TC,Can TTT,Choi WS

更新日期：2019-09-25 00:00:00

abstract：:TMEM230 mutations have been recently reported to cause autosomal dominant Parkinson's disease (PD). However, there are limited studies from different ethnic populations to support the role of TMEM230 in sporadic PD. In this study, we performed a comprehensive TMEM230 mutation screening in 550 sporadic PD patients and ...

journal_title：Scientific reports

authors： Shi CH,Li F,Shi MM,Yang ZH,Mao CY,Zhang SY,Wang H,Cheng Y,Yang J,Wu J,Xu YM

更新日期：2017-04-26 00:00:00

abstract：:The centromeric nucleosome is a key epigenetic determinant of centromere identity and function. Consequently, deciphering how CENP-A containing nucleosomes contribute structurally to centromere function is a fundamental question in chromosome biology. Here, we performed microsecond timescale all-atom molecular dynamic...

journal_title：Scientific reports

authors： Winogradoff D,Zhao H,Dalal Y,Papoian GA

更新日期：2015-11-25 00:00:00

abstract：:Empathetic verbal feedback from others has been shown to alleviate the intensity of experimental pain. To investigate the brain changes associated with this effect, we conducted 3T-fMRI measurements in 30 healthy subjects who received painful thermal stimuli on their left hand while overhearing empathetic, neutral or ...

journal_title：Scientific reports

authors： Fauchon C,Faillenot I,Quesada C,Meunier D,Chouchou F,Garcia-Larrea L,Peyron R

更新日期：2019-06-10 00:00:00

abstract：:There has been a developing technology in algae with pharmaceuticals wastewater. However, the effect and the underlying mechanism of pharmaceuticals on algae are not well understood. To investigate the effect and mechanism of pharmaceuticalson microalgae, four pharmaceuticals of clofibric acid (CLF), ciprofloxacin (CI...

journal_title：Scientific reports

authors： Zhang Y,Guo J,Yao T,Zhang Y,Zhou X,Chu H

更新日期：2019-02-07 00:00:00

abstract：:Hydrophilic polymers have garnered much attention due to their critical roles in various applications such as molecular separation membranes, bio-interfaces, and surface engineering. However, a long-standing problem is that their mechanical properties usually deteriorate at high relative humidity (RH). Through the sim...

journal_title：Scientific reports

authors： Liu T,An QF,Zhao Q,Wu JK,Song YH,Zhu BK,Gao CJ

更新日期：2015-01-14 00:00:00

abstract：:Twisting light in both phase and intensity has recently drawn great interests in various fields related to light-matter interactions such as optical manipulation of particles and quantum entanglement of photons. Conventionally, bulky optical components are required to produce such twisted optical beams, which signific...

journal_title：Scientific reports

authors： Zhang Y,Yang X,Gao J

更新日期：2018-03-20 00:00:00

abstract：:While designing the anti-inflammatory agents targeting cyclooxygenase-2 (COX-2), we first identified a water loop around the heme playing critical role in the enzyme catalysis. The results of molecular dynamic studies supported by the strong hydrogen-bonding equilibria of the participating atoms, radical stabilization...

journal_title：Scientific reports

authors： Kaur M,Kaur B,Kaur J,Kaur A,Bhatti R,Singh P

更新日期：2020-07-01 00:00:00

abstract：:Orthographic regularity is important for processing Chinese characters. However, the issues how orthographic regularity influences the visual recognition of real Chinese characters and whether common processes related to the potential effect exist between successive (SUCC) and concurrent (CONC) conditions with asynchr...

journal_title：Scientific reports

authors： He W,Fan C,Ren J,Liu T,Zhang M,Luo W

更新日期：2016-03-23 00:00:00

abstract：:Silver nanoparticles (AgNPs) have been extensively used and are considered as an emerging contaminant in the ocean. The environmental contamination of AgNPs is expected to increase greatly over time, and cetaceans, as the top ocean predators, will suffer the negative impacts of AgNPs. In the present study, we investig...

journal_title：Scientific reports

authors： Li WT,Chang HW,Yang WC,Lo C,Wang LY,Pang VF,Chen MH,Jeng CR

更新日期：2018-04-04 00:00:00

abstract：:The focus of this study is to evaluate the efficacy of Machine Learning (ML) algorithms in the long-lead prediction of El Niño (La Niña) Modoki (ENSO Modoki) index (EMI). We evaluated two widely used non-linear ML algorithms namely Support Vector Regression (SVR) and Random Forest (RF) to forecast the EMI at various l...

journal_title：Scientific reports

authors： Pal M,Maity R,Ratnam JV,Nonaka M,Behera SK

更新日期：2020-01-15 00:00:00

abstract：:Artificial tissues constructed from therapeutic cells offer a promising approach for improving the treatment of severe peripheral nerve injuries. In this study the effectiveness of using CTX0E03, a conditionally immortalised human neural stem cell line, as a source of allogeneic cells for constructing living artificia...

journal_title：Scientific reports

authors： O'Rourke C,Day AGE,Murray-Dunning C,Thanabalasundaram L,Cowan J,Stevanato L,Grace N,Cameron G,Drake RAL,Sinden J,Phillips JB

更新日期：2018-02-13 00:00:00

abstract：:Solid-state femtosecond lasers have stimulated the broad adoption of multiphoton microscopy in the modern laboratory. However, these devices remain costly. Fiber lasers offer promise as a means to inexpensively produce ultrashort pulses of light suitable for nonlinear microscopy in compact, robust and portable devices...

journal_title：Scientific reports

authors： Davoudzadeh N,Ducourthial G,Spring BQ

更新日期：2019-03-12 00:00:00

abstract：:The Acoustic Complexity Index (ACI) is increasingly applied to the study of biodiversity in aquatic habitats. However, it remains unknown which types of acoustic information are highlighted by this index in underwater environments. This study explored the robustness of the ACI to fine variations in fish sound abundanc...

journal_title：Scientific reports

authors： Bolgan M,Amorim MCP,Fonseca PJ,Di Iorio L,Parmentier E

更新日期：2018-07-12 00:00:00

abstract：:Mitochondria-targeted antioxidants are known to alleviate mitochondrial oxidative damage that is associated with a variety of diseases. Here, we showed that SkQ1, a decyltriphenyl phosphonium cation conjugated to a quinone moiety, exhibited strong antibacterial activity towards Gram-positive Bacillus subtilis, Mycobac...

journal_title：Scientific reports

authors： Nazarov PA,Osterman IA,Tokarchuk AV,Karakozova MV,Korshunova GA,Lyamzaev KG,Skulachev MV,Kotova EA,Skulachev VP,Antonenko YN

更新日期：2017-05-03 00:00:00

abstract：:Nowadays, one of the main challenges is moving towards an eco-sustainable agriculture, able to preserve the food production through a reduced use of pesticides. Current global food sustenance by intensive agriculture is mainly based on economic crop monocultures and drastically reduces the biodiversity, increasing the...

journal_title：Scientific reports

authors： Zambon Y,Contaldo N,Laurita R,Várallyay E,Canel A,Gherardi M,Colombo V,Bertaccini A

更新日期：2020-11-05 00:00:00

abstract：:Bacterial vaginosis (BV) is associated with HIV acquisition and adverse pregnancy outcomes. Recurrence after metronidazole treatment is high. HIV-negative, non-pregnant Rwandan BV patients were randomized to four groups (n = 17/group) after seven-day oral metronidazole treatment: behavioral counseling only (control), ...

journal_title：Scientific reports

authors： van de Wijgert JHHM,Verwijs MC,Agaba SK,Bronowski C,Mwambarangwe L,Uwineza M,Lievens E,Nivoliez A,Ravel J,Darby AC

更新日期：2020-03-03 00:00:00

abstract：:Cell-to-cell heterogeneity is driven by stochasticity in intracellular reactions and the population dynamics. While these sources are usually studied separately, we develop an agent-based framework that accounts for both factors while tracking every single cell of a growing population. Apart from the common intrinsic ...

journal_title：Scientific reports

authors： Thomas P

更新日期：2019-01-24 00:00:00

abstract：:Campylobacteriosis typically manifests as a short-lived, self-limiting gastrointestinal infection in humans, however prolonged infection can be seen in cases with underlying immunodeficiency. Public Health England received 25 isolates of Campylobacter jejuni from an individual with combined variable immunodeficiency o...

journal_title：Scientific reports

authors： Barker CR,Painset A,Swift C,Jenkins C,Godbole G,Maiden MCJ,Dallman TJ

更新日期：2020-06-22 00:00:00

abstract：:Contest behaviour, and in particular the propensity to attack an unfamiliar conspecific, is influenced by an individual's aggressiveness, as well as by experience of winning and losing (so called 'winner-loser effects'). Individuals vary in aggressiveness and susceptibility to winner-loser effects but the relationship...

journal_title：Scientific reports

authors： Oldham L,Camerlink I,Arnott G,Doeschl-Wilson A,Farish M,Turner SP

更新日期：2020-08-07 00:00:00

abstract：:Brain hypometabolism is a common epilepsy-related finding in both patients and animal models. Fluorodeoxyglucose positron emission tomography studies have shown that recurrent seizures lead to reduced glucose metabolism in certain brain regions, but no studies have definitively determined whether this induces epilepto...

journal_title：Scientific reports

authors： Zhang H,Gao G,Zhang Y,Sun Y,Li H,Dong S,Ma W,Liu B,Wang W,Wu H,Zhang H

更新日期：2017-07-19 00:00:00

abstract：:Amorphous solid dispersion (ASD) is a widely employed formulation technique for drugs with poor aqueous solubility. Polymers are integral components of ASDs, but mechanisms by which polymers lead to the generation and maintenance of supersaturated solutions, which enhance oral absorption in vivo, are poorly understood...

journal_title：Scientific reports

authors： Wilson VR,Lou X,Osterling DJ,Stolarik DF,Jenkins GJ,Nichols BLB,Dong Y,Edgar KJ,Zhang GGZ,Taylor LS

更新日期：2020-10-28 00:00:00

abstract：:Perpendicular magnetization and precise control over the magnetic easy axis in magnetic thin film is necessary for a variety of applications, particularly in magnetic recording media. A strong (111) orientation is successfully achieved in the CoFe2O4 (CFO) thin film at relatively low substrate temperature of 100 °C, w...

journal_title：Scientific reports

authors： Shirsath SE,Liu X,Yasukawa Y,Li S,Morisako A

更新日期：2016-07-20 00:00:00

abstract：:Genetic alterations identified in adjacent normal appearing tissue in bladder cancer patients are indicative of a field disease. Here we assessed normal urothelium transformation and intra-tumour heterogeneity (ITH) in four patients with bladder cancer. Exome sequencing identified private acquired mutations in a lymph...

journal_title：Scientific reports

authors： Thomsen MBH,Nordentoft I,Lamy P,Vang S,Reinert L,Mapendano CK,Høyer S,Ørntoft TF,Jensen JB,Dyrskjøt L

更新日期：2017-09-15 00:00:00

abstract：:One current concept suggests that unchecked proliferation of clonally selected precursors of endothelial cells (ECs) contribute to severe pulmonary arterial hypertension (PAH). We hypothesized that clonally selected ECs expressing the progenitor marker CD117 promote severe occlusive pulmonary hypertension (PH). The re...

journal_title：Scientific reports

authors： Bhagwani AR,Farkas D,Harmon B,Authelet KJ,Cool CD,Kolb M,Goncharova E,Yoder MC,Clauss M,Freishtat R,Farkas L

更新日期：2020-01-24 00:00:00

abstract：:Low-losses and directionality effects exhibited by High Refractive Index Dielectric particles make them attractive for applications where radiation direction control is relevant. For instance, isolated metallo-dielectric core-shell particles or aggregates (dimers) of High Refractive Index Dielectric particles have bee...

journal_title：Scientific reports

authors： Barreda ÁI,Saleh H,Litman A,González F,Geffrin JM,Moreno F

更新日期：2018-05-22 00:00:00

abstract：:The ability to perform not only elementally but also isotopically sensitive detection and analysis at standoff distances is impor-tant for remote sensing applications in diverse ares, such as nuclear nonproliferation, environmental monitoring, geophysics, and planetary science. We demonstrate isotopically sensitive re...

journal_title：Scientific reports

authors： Hartig KC,Ghebregziabher I,Jovanovic I

更新日期：2017-03-08 00:00:00