Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry.

abstract：:Laser-Stimulated Fluorescence (LSF) is used to identify fully fledged feathering in the hatchling enantiornithine bird specimen MPCM-LH-26189, supporting precocial nesting behavior in this extinct group. The LSF results include the detection of a long pennaceous wing feather as well as cover feathers around the body. ...

journal_title：Scientific reports

authors： Kaye TG,Pittman M,Marugán-Lobón J,Martín-Abad H,Sanz JL,Buscalioni AD

更新日期：2019-03-21 00:00:00

abstract：:The arrival of the Longobards in Northern Italy in 568 CE marked a period of renewed political stability in the Peninsula after the collapse of the Western Roman Empire. The trajectory of the spread of Longobards in Italy across the Alps and into the South is known from many literary sources. However, their mobility a...

journal_title：Scientific reports

authors： Francisci G,Micarelli I,Iacumin P,Castorina F,Di Vincenzo F,Di Matteo M,Giostra C,Manzi G,Tafuri MA

更新日期：2020-07-15 00:00:00

abstract：:Individuals differ in their level of general anxiety as well as in their level of anxiety towards specific activities, such as mathematics and spatial tasks. Both specific anxieties correlate moderately with general anxiety, but the aetiology of their association remains unexplored. Moreover, the factor structure of s...

journal_title：Scientific reports

authors： Malanchini M,Rimfeld K,Shakeshaft NG,Rodic M,Schofield K,Selzam S,Dale PS,Petrill SA,Kovas Y

更新日期：2017-02-21 00:00:00

abstract：:The purpose of the present study was to assess the differential intraocular pressure response (IOP) to dexamethasone (DEX) treatment at two dose levels (100 or 500 nM) in perfusion cultured Indian cadaveric eyes to investigate glucocorticoid (GC) responsiveness. In a human organ-cultured anterior segment (HOCAS) set-u...

journal_title：Scientific reports

authors： Haribalaganesh R,Gowri Priya C,Sharmila R,Krishnadas S,Muthukkaruppan V,Willoughby CE,Senthilkumari S

更新日期：2021-01-12 00:00:00

abstract：:A bistable toggle switch is a paradigmatic model in the field of biology. The dynamics of the system induced by Gaussian noise has been intensively investigated, but Gaussian noise cannot incorporate large bursts typically occurring in real experiments. This paper aims to examine effects of variations from one protein...

journal_title：Scientific reports

authors： Xu Y,Li Y,Zhang H,Li X,Kurths J

更新日期：2016-08-19 00:00:00

abstract：:Alcohol consumption has been shown to cause dysbiosis, but the mechanism involved in it is unknown. Recurrent colitis is known to induce expression of α-defensins in the colon, but the effect of alcohol consumption on it is not known. We investigated the effect of ethanol on α-defensin expression in the small intestin...

journal_title：Scientific reports

authors： Shukla PK,Meena AS,Rao V,Rao RG,Balazs L,Rao R

更新日期：2018-11-02 00:00:00

abstract：:Fabrication of uniform vertically-aligned titanium dioxide nanorods (TiO2 NRs) was achieved by hydrothermal growth on a fluorine-doped tin oxide (FTO) glass substrate. The substrate was coated by a TiO2 seed layer composed of titanium (IV) butoxide (TBO) as a precursor in an HCl solution. To reduce the amount of toxic...

journal_title：Scientific reports

authors： Prathan A,Sanglao J,Wang T,Bhoomanee C,Ruankham P,Gardchareon A,Wongratanaphisan D

更新日期：2020-05-15 00:00:00

abstract：:Urothelial carcinoma (UC) is a common disease causing significant morbidity and mortality as well as considerable costs for health systems. Extensive aberrant methylation of DNA is broadly documented in early UC, contributing to genetic instability, altered gene expression and tumor progression. However the triggers i...

journal_title：Scientific reports

authors： Erichsen L,Seifert HH,Schulz WA,Hoffmann MJ,Niegisch G,Araúzo-Bravo MJ,Bendhack ML,Poyet C,Hermanns T,Beermann A,Hassan M,Theis L,Mahmood W,Santourlidis S

更新日期：2020-03-02 00:00:00

abstract：:In ART programs in sub-Saharan Africa, a growing proportion of HIV-infected persons initiating first-line antiretroviral therapy (ART) have a history of prior antiretroviral drug use (PAU). We assessed the effect of PAU on the risk of pre-treatment drug resistance (PDR) and virological failure (VF) in a multicountry c...

journal_title：Scientific reports

authors： Inzaule SC,Kityo CM,Siwale M,Akanmu AS,Wellington M,de Jager M,Ive P,Mandaliya K,Stevens W,Boender TS,Ondoa P,Sigaloff KCE,Naniche D,Rinke de Wit TF,Hamers RL

更新日期：2018-10-25 00:00:00

abstract：:Risk of malaria in infants can be influenced by prenatal factors. In this study, the potential for placental parasitemia at delivery in predicting susceptibility of infants to Plasmodium falciparum (Pf) infections was evaluated. Seventy-two newborns of mothers who were placental malaria negative (PM-) and of mothers w...

journal_title：Scientific reports

authors： Tassi Yunga S,Fouda GG,Sama G,Ngu JB,Leke RGF,Taylor DW

更新日期：2018-01-09 00:00:00

abstract：:Detailed measurements of physical, chemical and biological dynamics in groundwater are key to understanding the important processes in place and their influence on water quality - particularly when used for drinking water. Measuring temporal bacterial dynamics at high frequency is challenging due to the limitations in...

journal_title：Scientific reports

authors： Besmer MD,Epting J,Page RM,Sigrist JA,Huggenberger P,Hammes F

更新日期：2016-12-07 00:00:00

abstract：:Artificial grasslands play a role in carbon storage on the Qinghai-Tibetan Plateau. The artificial grasslands exhibit decreased proportions of graminate and increased species richness with age. However, the effect of the graminate proportions and species richness on ecosystem C stocks in artificial grasslands have not...

journal_title：Scientific reports

authors： Xu L,Yao B,Wang W,Wang F,Zhou H,Shi J,Zhao X

更新日期：2017-01-09 00:00:00

abstract：:Theileria annulata is a haemoprotozoan parasite that causes a cancer-like illness known as tropical theileriosis in cattle. In the course of analyzing the genetic diversity of T. annulata in Sri Lanka, we observed that merozoite-piroplasm surface antigen (tams1) and surface protein (tasp)-like gene sequences obtained ...

journal_title：Scientific reports

authors： Sivakumar T,Fujita S,Tuvshintulga B,Kothalawala H,Silva SSP,Yokoyama N

更新日期：2019-11-06 00:00:00

abstract：:To explore the feasibility of 3D-printed navigation template in proximal femoral varus rotation and shortening osteotomy for older children with developmental dysplasia of the hip (DDH). Between June 2014 and May 2015, navigation templates were designed and used for 12 DDH patients. Surgical information and outcomes w...

journal_title：Scientific reports

authors： Zheng P,Xu P,Yao Q,Tang K,Lou Y

更新日期：2017-03-21 00:00:00

abstract：:Urinary concentrations of the major progesterone (P4) metabolite pregnanediol-3-glucuronide (PDG) are used to confirm ovulation. We aimed to determine whether automated immunoassay of urinary P4 was as efficacious as PDG to confirm ovulation. Daily urine samples from 20 cycles in 14 healthy women in whom ovulation was...

journal_title：Scientific reports

authors： Gifford RM,Howie F,Wilson K,Johnston N,Todisco T,Crane M,Greeves JP,Skorupskaite K,Woods DR,Reynolds RM,Anderson RA

更新日期：2018-12-04 00:00:00

abstract：:Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the cerebellum. Advances in molecular genomics have led to the identification of defined subgroups which are associated with distinct clinical prognoses. Despite this classification, standard therapies for all subgroups often leave child...

journal_title：Scientific reports

authors： Mather RL,Loveson KF,Fillmore HL

更新日期：2019-06-13 00:00:00

abstract：:Due to their small dimensions, electrophysiology on thin and intricate axonal branches in support of understanding their role in normal and diseased brain function poses experimental challenges. To reduce experimental complexity, we coupled microelectrode arrays (MEAs) to bi-level microchannel devices for the long-ter...

journal_title：Scientific reports

authors： Habibey R,Latifi S,Mousavi H,Pesce M,Arab-Tehrany E,Blau A

更新日期：2017-08-17 00:00:00

abstract：:Human risk-taking attitudes can be influenced by two logically equivalent but descriptively different frames, termed the framing effect. The classic hypothetical vignette-based task (Asian disease problem) and a recently developed reward-based gambling task have been widely used to assess individual differences in the...

journal_title：Scientific reports

authors： Zhen S,Yu R

更新日期：2016-07-20 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) promotes insulin secretion from pancreatic β-cells in a glucose dependent manner. Several pathways mediate this action by rapid, kinase phosphorylation-dependent, but gene expression-independent mechanisms. Since GLP-1-induced insulin secretion requires glucose metabolism, we aimed to a...

journal_title：Scientific reports

authors： Carlessi R,Chen Y,Rowlands J,Cruzat VF,Keane KN,Egan L,Mamotte C,Stokes R,Gunton JE,Bittencourt PIH,Newsholme P

更新日期：2017-06-01 00:00:00

abstract：:In this paper we report for the first time an n-type carbon nanotube field effect transistor which is air- and water-stable, a necessary requirement for electrolyte gated CMOS circuit operation. The device is obtained through a simple process, where the native p-type transistor is converted to an n-type. This conversi...

journal_title：Scientific reports

authors： Joshi S,Bhatt VD,Jaworska E,Michalska A,Maksymiuk K,Becherer M,Gagliardi A,Lugli P

更新日期：2018-07-30 00:00:00

abstract：:Potato (Solanum tuberosum) is an important staple crop worldwide, it has been cultivated in the Andean Altiplano under low-input farming practices at high altitudes and under harsh environment for centuries. We analyzed secondary metabolite (SM) gene diversity encoded in the potato rhizosphere microbiome during plant ...

journal_title：Scientific reports

authors： Aleti G,Nikolić B,Brader G,Pandey RV,Antonielli L,Pfeiffer S,Oswald A,Sessitsch A

更新日期：2017-05-24 00:00:00

abstract：:Despite extensive efforts in studying radioactive aerosols, including the transmission of radionuclides in different chemical matrices throughout the body, the internal organ-specific radiation dose due to inhaled radioactive aerosols has largely relied on experimental deposition data and simplified human phantoms. Co...

journal_title：Scientific reports

authors： Talaat K,Xi J,Baldez P,Hecht A

更新日期：2019-11-25 00:00:00

abstract：:The aim of the present study was to evaluate sleep and mood disorders in patients with irritating ocular diseases. The study design was a cross-sectional/case-control study conducted in six eye clinics. Out of 715 outpatients diagnosed with irritating ocular surface diseases and initially enrolled, 301 patients with d...

journal_title：Scientific reports

authors： Ayaki M,Kawashima M,Negishi K,Kishimoto T,Mimura M,Tsubota K

更新日期：2016-03-01 00:00:00

abstract：:The intrauterine environment is particularly vulnerable to environmental exposures. We previously established a mouse model that provided evidence for pregnancy complications and placental anti-angiogenesis in response to Aroclor 1254 (A-1254), a mixture of polychlorinated biphenyls (PCBs). Importantly, these effects ...

journal_title：Scientific reports

authors： Kalkunte S,Huang Z,Lippe E,Kumar S,Robertson LW,Sharma S

更新日期：2017-01-10 00:00:00

abstract：:In this study, genomic DNA was screened from Halobacillus andaensis NEAU-ST10-40T by selection in Escherichia coli KNabc lacking three major Na+/H+ antiporters. One gene designated upf0118 exhibiting Na+(Li+)/H+ antiport activity was finally cloned. Protein alignment showed that UPF0118 shares the highest identity of ...

journal_title：Scientific reports

authors： Dong P,Wang L,Song N,Yang L,Chen J,Yan M,Chen H,Zhang R,Li J,Abdel-Motaal H,Jiang J

更新日期：2017-04-04 00:00:00

abstract：:The intrinsic functional architecture of the brain supports moment-to-moment maintenance of an internal model of the world. We hypothesized and found three interdependent architectural gradients underlying the organization of intrinsic functional connectivity within the human cerebral cortex. We used resting state fMR...

journal_title：Scientific reports

authors： Zhang J,Abiose O,Katsumi Y,Touroutoglou A,Dickerson BC,Barrett LF

更新日期：2019-11-04 00:00:00

abstract：:The pearl oyster is one of the rare animal models that support two distinct genomes, through the surgical graft process operated for culture pearl production. This grafted organism is assimilated to a chimera whose physiological functioning remains poorly known. The question of the energy expenditure comparison betwee...

journal_title：Scientific reports

authors： Le Moullac G,Soyez C,Ky CL

更新日期：2018-05-14 00:00:00

abstract：:When acoustic signals from different sound sources are mixed upon arrival at the ears, the auditory system organizes these acoustic elements by their features. This study shows that individuals with autism spectrum disorder (ASD) performed better in terms of hearing a target sequence among distractors that had similar...

journal_title：Scientific reports

authors： Lin IF,Yamada T,Komine Y,Kato N,Kashino M

更新日期：2015-05-22 00:00:00

abstract：:Reversible polymeric networks can show self-healing properties due to their ability to reassemble after application of stress and fracture, but typically the relation between equilibrium molecular dynamics and self-healing kinetics has been difficult to disentangle. Here we present a well-characterized, self-assembled...

journal_title：Scientific reports

authors： Yan T,Schröter K,Herbst F,Binder WH,Thurn-Albrecht T

更新日期：2016-09-01 00:00:00

abstract：:Biosorption is a cost-effective and simple technique for removing heavy metals and rare earth elements from aqueous solution. Here, metals were recovered from aqueous solutions using phosphorylated dry baker's yeast cells. The cells were phosphorylated using cyclo-triphosphate, Na3P3O9. The total P content of the phos...

journal_title：Scientific reports

authors： Ojima Y,Kosako S,Kihara M,Miyoshi N,Igarashi K,Azuma M

更新日期：2019-01-18 00:00:00