Abstract:
:The study of the synchronization patterns of small neuron networks that control several biological processes has become an interesting growing discipline. Some of these synchronization patterns of individual neurons are related to some undesirable neurological diseases, and they are believed to play a crucial role in the emergence of pathological rhythmic brain activity in different diseases, like Parkinson's disease. We show how, with a suitable combination of short and weak global inhibitory and excitatory stimuli over the whole network, we can switch between different stable bursting patterns in small neuron networks (in our case a 3-neuron network). We develop a systematic study showing and explaining the effects of applying the pulses at different moments. Moreover, we compare the technique on a completely symmetric network and on a slightly perturbed one (a much more realistic situation). The present approach of using global stimuli may allow to avoid undesirable synchronization patterns with nonaggressive stimuli.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lozano Á,Rodríguez M,Barrio Rdoi
10.1038/srep23622subject
Has Abstractpub_date
2016-03-29 00:00:00pages
23622issn
2045-2322pii
srep23622journal_volume
6pub_type
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