Alpha B-crystallin C-802G polymorphism and colorectal cancer susceptibility and clinical outcome in Chinese population.

abstract：:Adenosine receptors (ARs) are potential therapeutic targets for Parkinson's disease, diabetes, pain, stroke and cancers. Prediction of subtype selectivity is therefore important from both therapeutic and mechanistic perspectives. In this paper, we introduced a shape similarity profile as molecular descriptor, namely t...

journal_title：Scientific reports

authors： He SB,Ben Hu,Kuang ZK,Wang D,Kong DX

更新日期：2016-11-04 00:00:00

abstract：:Peripheral nerve injury leads to various injury-induced responses in sensory neurons including physiological pain, neuronal cell death, and nerve regeneration. In this study, we performed single-cell RNA-sequencing (scRNA-seq) analysis of mouse nonpeptidergic nociceptors (NP), peptidergic nociceptors (PEP), and large ...

journal_title：Scientific reports

authors： Hu G,Huang K,Hu Y,Du G,Xue Z,Zhu X,Fan G

更新日期：2016-08-25 00:00:00

abstract：:Invasive alien species are regarded a nuisance. This extends into a lack of conservation efforts in their native range. As a consequence, conservation of e.g. range-edge populations is neglected. Gobiidae have many representatives of alien species in European freshwaters, and therefore they have a bad reputation. Obje...

journal_title：Scientific reports

authors： Kukuła K,Ortyl B,Bylak A

更新日期：2019-12-23 00:00:00

abstract：:We present a comprehensive study of a magnetic sensor system that benefits from a new technique to substantially increase the magnetoelastic coupling of surface acoustic waves (SAW). The device uses shear horizontal acoustic surface waves that are guided by a fused silica layer with an amorphous magnetostrictive FeCoS...

journal_title：Scientific reports

authors： Kittmann A,Durdaut P,Zabel S,Reermann J,Schmalz J,Spetzler B,Meyners D,Sun NX,McCord J,Gerken M,Schmidt G,Höft M,Knöchel R,Faupel F,Quandt E

更新日期：2018-01-10 00:00:00

abstract：:The present study shows chronic adjustments in the myotendinous junction (MTJ) in response to different ladder-based resistance training (LRT) protocols. Thirty adult male Wistar rats were divided into groups: sedentary (S), calisthenics (LRT without additional load [C]), and resistance-trained (LRT with extra weight ...

journal_title：Scientific reports

authors： Pimentel Neto J,Rocha LC,Barbosa GK,Jacob CDS,Krause Neto W,Watanabe IS,Ciena AP

更新日期：2020-08-24 00:00:00

abstract：:A cross-correlative precession electron diffraction - atom probe tomography investigation of Cr segregation in a Fe(Cr) nanocrystalline alloy was undertaken. Solute segregation was found to be dependent on grain boundary type. The results of which were compared to a hybrid Molecular Dynamics and Monte Carlo simulation...

journal_title：Scientific reports

authors： Zhou X,Yu XX,Kaub T,Martens RL,Thompson GB

更新日期：2016-10-06 00:00:00

abstract：:Soil physical properties and soil organic carbon (SOC) are considered as important factors of soil quality. Arable land, grassland, and forest land coexist in the saline-alkali reclamation area of the Yellow River Delta (YRD), China. Such different land uses strongly influence the services of ecosystem to induce soil ...

journal_title：Scientific reports

authors： Jiao S,Li J,Li Y,Xu Z,Kong B,Li Y,Shen Y

更新日期：2020-11-23 00:00:00

abstract：:Core-shell refractory plasmonic nanoparticles are used as excellent nanoantennas to improve the efficiency of lead-free perovskite solar cells (PSCs). SiO2 is used as the shell coating due to its high refractive index and low extinction coefficient, enabling the control over the sunlight directivity. An optoelectronic...

journal_title：Scientific reports

authors： Mohsen AA,Zahran M,Habib SED,Allam NK

更新日期：2020-04-21 00:00:00

abstract：:Nonalcoholic fibrosing steatohepatitis is a uniform process throughout nonalcoholic fatty liver disease (NAFLD). MicroRNAs (miRNAs) have been suggested to modulate cellular processes in liver diseases. However, the functional role of miRNAs in nonalcoholic fibrosing steatohepatitis is largely unclear. In this study, w...

journal_title：Scientific reports

authors： Du J,Niu X,Wang Y,Kong L,Wang R,Zhang Y,Zhao S,Nan Y

更新日期：2015-11-05 00:00:00

abstract：:Anisotropic Fe3O4 nanoparticle and a series of its graphene composites have been successfully prepared as high-frequency absorbers. The crystal structure, morphology and magnetic property of the samples were detailed characterized through X-ray diffractometer (XRD), transmission electron microscopy (TEM) and vibrating...

journal_title：Scientific reports

authors： Yin Y,Zeng M,Liu J,Tang W,Dong H,Xia R,Yu R

更新日期：2016-05-04 00:00:00

abstract：:Complement Receptor Immunoglobulin (CRIg), selectively expressed by macrophages, plays an important role in innate immunity by promoting phagocytosis of bacteria. Thus modulation of CRIg on macrophages by cytokines can be an important mechanism by which cytokines regulate anti-microbial immunity. The effects of the cy...

journal_title：Scientific reports

authors： Munawara U,Small AG,Quach A,Gorgani NN,Abbott CA,Ferrante A

更新日期：2017-06-22 00:00:00

abstract：:KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current study aimed to design a...

journal_title：Scientific reports

authors： Schelleckes K,Schmitz B,Lenders M,Mewes M,Brand SM,Brand E

更新日期：2018-03-09 00:00:00

abstract：:We previously demonstrated that ABCD4 does not localize to peroxisomes but rather, the endoplasmic reticulum (ER), because it lacks the NH2-terminal hydrophilic region required for peroxisomal targeting. It was recently reported that mutations in ABCD4 result in a failure to release vitamin B12 from lysosomes. A simil...

journal_title：Scientific reports

authors： Kawaguchi K,Okamoto T,Morita M,Imanaka T

更新日期：2016-07-26 00:00:00

abstract：:Protein structure prediction is a grand challenge. Prediction of protein structures via the representations using backbone dihedral angles has recently achieved significant progress along with the on-going surge of deep neural network (DNN) research in general. However, we observe that in the protein backbone angle pr...

journal_title：Scientific reports

authors： Mataeimoghadam F,Newton MAH,Dehzangi A,Karim A,Jayaram B,Ranganathan S,Sattar A

更新日期：2020-11-10 00:00:00

abstract：:The transcriptome of the endometrium early postpartum was profiled to determine if inflammatory gene expression was elevated in cows which subsequently developed uterine disease. Endometrial cytobrush samples were collected at 7 days postpartum (DPP) from 112 Holstein-Friesian dairy cows, from which 27 were retrospect...

journal_title：Scientific reports

authors： Brewer A,Cormican P,Lim JJ,Chapwanya A,O'Farrelly C,Meade KG

更新日期：2020-10-26 00:00:00

abstract：:Laser Capture Microdissection (LCM) is a powerful tool to isolate and study gene expression pattern of desired and less accessible cells or tissues from a heterogeneous population. Existing LCM-based methods fail to obtain high quality RNA including small RNAs from small microdissected plant tissue and therefore, are ...

journal_title：Scientific reports

authors： Gautam V,Singh A,Singh S,Sarkar AK

更新日期：2016-02-10 00:00:00

abstract：:Scaling evolutionary trees to time is essential for understanding the origins of clades. Recently developed methods allow including the entire fossil record known for the group of interest and eliminated the need for specifying prior distributions for node ages. Here we apply the fossilized birth-death (FBD) approach ...

journal_title：Scientific reports

authors： Šmíd J,Tolley KA

更新日期：2019-04-02 00:00:00

abstract：:Optimal mental workload plays a key role in driving performance. Thus, driver-assisting systems that automatically adapt to a drivers current mental workload via brain-computer interfacing might greatly contribute to traffic safety. To design economic brain computer interfaces that do not compromise driver comfort, it...

journal_title：Scientific reports

authors： Geissler CF,Schneider J,Frings C

更新日期：2021-01-12 00:00:00

abstract：:The Lesotho guidelines for the management of drug-resistant tuberculosis (TB) recommend initiation of patients diagnosed with rifampicin resistant (RR)-TB on a standardized drug resistant regimen while awaiting confirmation of rifampicin resistant TB (RR-TB) and complete drug susceptibility test results. Review of dia...

journal_title：Scientific reports

authors： Katende B,Esterhuizen TM,Dippenaar A,Warren RM

更新日期：2020-02-05 00:00:00

abstract：:Endoplasmic reticulum (ER) stress preconditioning protects cells against methylmercury (MeHg) cytotoxicity by inducing integrated stress responses such as eIF2α phosphorylation, ATF4 accumulation, and nonsense-mediated mRNA decay (NMD) suppression. Here we demonstrated that ER stress preconditioning results in the upr...

journal_title：Scientific reports

authors： Usuki F,Fujimura M,Yamashita A

更新日期：2017-09-28 00:00:00

abstract：:Spectroscopic techniques combined with chemometrics methods have proven to be effective tools for the discrimination of objects with similar properties. In this work, terahertz time-domain spectroscopy (THz-TDS) combined with discriminate analysis (DA) and principal component analysis (PCA) with derivative pretreatmen...

journal_title：Scientific reports

authors： Xu W,Xie L,Ye Z,Gao W,Yao Y,Chen M,Qin J,Ying Y

更新日期：2015-07-08 00:00:00

abstract：:An atmospheric component of the Philippine-Taiwan Oscillations (PTOa) is used to examine its potential connection with tropical cyclone (TC) frequency in the western North Pacific in the period of 1979-2014. During positive PTOa years, more TCs are observed in the tropical western Pacific south of 18 °N where cyclonic...

journal_title：Scientific reports

authors： Chang YK,Miyazawa Y,Kodaira T,Behera S

更新日期：2018-11-29 00:00:00

abstract：:The usage of gelatin hydrogel is limited due to its instability and poor mechanical properties, especially under physiological conditions. Divalent metal ions present in gelatin such as Ca(2+) and Fe(2+) play important roles in the gelatin molecule interactions. The objective of this study was to determine the impact ...

journal_title：Scientific reports

authors： Xing Q,Yates K,Vogt C,Qian Z,Frost MC,Zhao F

更新日期：2014-04-16 00:00:00

abstract：:In arid and semiarid regions, low precipitation rates lead to soil salinity problems, which may limit plant establishment, growth, and survival. Herein, we investigated the NaCl stress effect on chlorophyll fluorescence, photosynthetic-pigments, movement and chloroplasts ultrastructure in chlorenchyma cells of Opuntia...

journal_title：Scientific reports

authors： Arias-Moreno DM,Jiménez-Bremont JF,Maruri-López I,Delgado-Sánchez P

更新日期：2017-08-17 00:00:00

abstract：:Techniques that manipulate DNA, a biomolecule with electrical properties, are in demand in various medical fields. This study fabricated a nanochannel with a conductive/semi-conductive interface using focused ion beams (FIBs) and introduced a nanochip technology to freely align, attach, and detach lambda DNAs in the i...

journal_title：Scientific reports

authors： Kang K,Jang Y,Jung J,Oh J

更新日期：2019-02-26 00:00:00

abstract：:Nature disasters and terrorist attacks have occurred globally in recent years. Posttraumatic stress disorder (PTSD) has gained increasing attention, but its incidence and comorbidities in the general population are different from those inside the disaster areas. The present study estimated incident PTSD and comorbid d...

journal_title：Scientific reports

authors： Chang JC,Yen AM,Chen HH,Chen SL,Chiu SY,Fann JC,Lee CS

更新日期：2017-01-27 00:00:00

abstract：:Charge noise is critical in the performance of gate-controlled quantum dots (QDs). Such information is not yet available for QDs made out of the new material graphene, where both substrate and edge states are known to have important effects. Here we show the 1/f noise for a microscopic graphene QD is substantially lar...

journal_title：Scientific reports

authors： Song XX,Li HO,You J,Han TY,Cao G,Tu T,Xiao M,Guo GC,Jiang HW,Guo GP

更新日期：2015-01-30 00:00:00

abstract：:α-Dystroglycanopathy (α-DGP) is a group of muscular dystrophy characterized by abnormal glycosylation of α-dystroglycan (α-DG), including Fukuyama congenital muscular dystrophy (FCMD), muscle-eye-brain disease, Walker-Warburg syndrome, and congenital muscular dystrophy type 1D (MDC1D), etc. LARGE, the causative gene f...

journal_title：Scientific reports

authors： Ohtsuka Y,Kanagawa M,Yu CC,Ito C,Chiyo T,Kobayashi K,Okada T,Takeda S,Toda T

更新日期：2015-02-09 00:00:00

abstract：:Individuals with Angelman syndrome (AS) are characterized by severe cognitive impairments alongside an enhanced drive for social engagement. As knowledge on imitation skills in this population is limited, we conducted the first controlled study of imitation in AS. We examined how 23 individuals with AS and 21 typicall...

journal_title：Scientific reports

authors： Micheletti S,Vivanti G,Renzetti S,Martelli P,Calza S,“Imitation in Angelman” Study Group.,Fazzi E

更新日期：2020-10-02 00:00:00

abstract：:Candida albicans biofilm formation is governed by a regulatory circuit comprising nine transcription factors which control a network of target genes. However, there are still unknown genes contributing to biofilm features. Thus, the GRACE library was screened to identify genes involved in mature biofilm development. T...

journal_title：Scientific reports

authors： Costa ACBP,Omran RP,Correia-Mesquita TO,Dumeaux V,Whiteway M

更新日期：2019-06-24 00:00:00