Association between optical coherence tomography based retinal microvasculature characteristics and myocardial infarction in young men.

Abstract:

:Incident myocardial infarction (MI) is a leading cause of adult mortality in the United States. However, because MI has a relatively low incidence in the young population, little information exists on the disease in younger adults. Because the retina has the unique quality that its vasculature is readily and noninvasively visible, the retina is frequently studied to evaluate correlations between vessels and cardiovascular diseases. In the current study, we evaluated the retinal microvasculature of patients who had experienced an MI before 50 years of age (n = 53 subjects) and age- and sex-matched patients who had not experienced an MI (n = 53 patients). We used circular optical coherence tomography (OCT) scans to image peripapillary venules and arterioles. The diameter of each vessel was measured and the respective arterial-venous ratio (AVR) was calculated. We did not detect any significant differences between MI and control subjects in retinal vessel calibre or AVR.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Kromer R,Tigges E,Rashed N,Pein I,Klemm M,Blankenberg S

doi

10.1038/s41598-018-24083-x

subject

Has Abstract

pub_date

2018-04-04 00:00:00

pages

5615

issue

1

issn

2045-2322

pii

10.1038/s41598-018-24083-x

journal_volume

8

pub_type

杂志文章
  • Association of SCN10A Polymorphisms with the Recurrence of Atrial Fibrillation after Catheter Ablation in a Chinese Han Population.

    abstract::The nonsynonymous SCN10A single nucleotide polymorphism (SNP) rs6795970 has been reported to associate with PR interval and atrial fibrillation (AF) and in strong linkage disequilibrium (LD) with the AF-associated SNP rs6800541. In this study, we investigated whether rs6795970 polymorphisms are associated with AF recu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep44003

    authors: Wu H,Xu J,Chen S,Zhou G,Qi B,Wei Y,Hu E,Tang D,Chen G,Li H,Zhao L,Shi Y,Liu S

    更新日期:2017-03-10 00:00:00

  • Risk Model for Prostate Cancer Using Environmental and Genetic Factors in the Spanish Multi-Case-Control (MCC) Study.

    abstract::Prostate cancer (PCa) is the second most common cancer among men worldwide. Its etiology remains largely unknown compared to other common cancers. We have developed a risk stratification model combining environmental factors with family history and genetic susceptibility. 818 PCa cases and 1,006 healthy controls were ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09386-9

    authors: Gómez-Acebo I,Dierssen-Sotos T,Fernandez-Navarro P,Palazuelos C,Moreno V,Aragonés N,Castaño-Vinyals G,Jiménez-Monleón JJ,Ruiz-Cerdá JL,Pérez-Gómez B,Ruiz-Dominguez JM,Molero JA,Pollán M,Kogevinas M,Llorca J

    更新日期:2017-08-21 00:00:00

  • The effect of lattice disorder on the low-temperature heat capacity of (U1-yThy)O2 and 238Pu-doped UO2.

    abstract::The low-temperature heat capacity of (U1-yThy)O2 and 238Pu-doped UO2 samples were determined using hybrid adiabatic relaxation calorimetry. Results of the investigated systems revealed the presence of the magnetic transition specific for UO2 in all three intermediate compositions of the uranium-thorium dioxide (y = 0....

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-51476-3

    authors: Vălu SO,De Bona E,Popa K,Griveau JC,Colineau E,Konings RJM

    更新日期:2019-10-21 00:00:00

  • A direct borohydride fuel cell with a polymer fiber membrane and non-noble metal catalysts.

    abstract::Polymer electrolyte membranes (PEM) and Pt-based catalysts are two crucial components which determine the properties and price of fuel cells. Even though, PEM faces problem of fuel crossover in liquid fuel cells such as direct methanol fuel cell (DMFC) and direct borohydride fuel cell (DBFC), which lowers power output...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep00567

    authors: Yang X,Liu Y,Li S,Wei X,Wang L,Chen Y

    更新日期:2012-01-01 00:00:00

  • Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis.

    abstract::Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6GhighCD11b+) and immature (Ly6GlowCD11b+) neutrophils. After chimaeric bone mar...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04538-3

    authors: Sánchez Á,Relaño C,Carrasco A,Contreras-Jurado C,Martín-Duce A,Aranda A,Alemany S

    更新日期:2017-07-10 00:00:00

  • Optic Disc Hemorrhage and Lamina Cribrosa Defects in Glaucoma Progression.

    abstract::Both disc hemorrhages (DH) and focal lamina cribrosa (LC) defects are recently considered as a progression factor in glaucoma. However, the clinical relevance of the presence of LC findings at the site of the DH has not yet been determined. We conducted a prospective study enrolling a total of 98 glaucoma eyes with DH...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-03828-0

    authors: Park HL,Lee J,Jung Y,Park CK

    更新日期:2017-06-14 00:00:00

  • An African loss-of-function CACNA1C variant p.T1787M associated with a risk of ventricular fibrillation.

    abstract::Calcium regulation plays a central role in cardiac function. Several variants in the calcium channel Cav1.2 have been implicated in arrhythmic syndromes. We screened patients with Brugada syndrome, short QT syndrome, early repolarisation syndrome, and idiopathic ventricular fibrillation to determine the frequency and ...

    journal_title:Scientific reports

    pub_type: 杂志文章,多中心研究

    doi:10.1038/s41598-018-32867-4

    authors: Blancard M,Debbiche A,Kato K,Cardin C,Sabrina G,Gandjbakhch E,Probst V,Haissaguerre M,Extramiana F,Hocini M,Olivier G,Leenhardt A,Guicheney P,Rougier JS

    更新日期:2018-10-02 00:00:00

  • Within-session verbal learning slope is predictive of lifespan delayed recall, hippocampal volume, and memory training benefit, and is heritable.

    abstract::Memory performance results from plasticity, the ability to change with experience. We show that benefit from practice over a few trials, learning slope, is predictive of long-term recall and hippocampal volume across a broad age range and a long period of time, relates to memory training benefit, and is heritable. Fir...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-78225-1

    authors: Walhovd KB,Bråthen ACS,Panizzon MS,Mowinckel AM,Sørensen Ø,de Lange AG,Krogsrud SK,Håberg A,Franz CE,Kremen WS,Fjell AM

    更新日期:2020-12-03 00:00:00

  • Brain regionalization genes are co-opted into shell field patterning in Mollusca.

    abstract::The 'brain regionalization genes' Six3/6, Otx, Pax2/5/8, Gbx, and Hox1 are expressed in a similar fashion in the deuterostome, ecdysozoan, and the cephalopod brain, questioning whether this holds also true for the remaining Mollusca. We investigated developmental Gbx-expression in representatives of both molluscan sis...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05605-5

    authors: Wollesen T,Scherholz M,Rodríguez Monje SV,Redl E,Todt C,Wanninger A

    更新日期:2017-07-14 00:00:00

  • SSA-ME Detection of cancer driver genes using mutual exclusivity by small subnetwork analysis.

    abstract::Because of its clonal evolution a tumor rarely contains multiple genomic alterations in the same pathway as disrupting the pathway by one gene often is sufficient to confer the complete fitness advantage. As a result, many cancer driver genes display mutual exclusivity across tumors. However, searching for mutually ex...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36257

    authors: Pulido-Tamayo S,Weytjens B,De Maeyer D,Marchal K

    更新日期:2016-11-03 00:00:00

  • Observed 3D Structure, Generation, and Dissipation of Oceanic Mesoscale Eddies in the South China Sea.

    abstract::Oceanic mesoscale eddies with horizontal scales of 50-300 km are the most energetic form of flows in the ocean. They are the oceanic analogues of atmospheric storms and are effective transporters of heat, nutrients, dissolved carbon, and other biochemical materials in the ocean. Although oceanic eddies have been ubiqu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep24349

    authors: Zhang Z,Tian J,Qiu B,Zhao W,Chang P,Wu D,Wan X

    更新日期:2016-04-14 00:00:00

  • Skeletal muscle cutoff values for sarcopenia diagnosis using T10 to L5 measurements in a healthy US population.

    abstract::Measurements of skeletal muscle cross-sectional area, index, and radiation attenuation utilizing clinical computed tomography (CT) scans are used in assessments of sarcopenia, the loss of skeletal muscle mass and function associated with aging. To classify individuals as sarcopenic, sex-specific cutoffs for 'low' valu...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29825-5

    authors: Derstine BA,Holcombe SA,Ross BE,Wang NC,Su GL,Wang SC

    更新日期:2018-07-27 00:00:00

  • The effect of high glucose on lipid metabolism in the human placenta.

    abstract::Diabetes mellitus (DM) during pregnancy can result in fetal overgrowth, likely due to placental dysfunction, which has health consequences for the infant. Here we test our prediction from previous work using a placental cell line that high glucose concentrations affect placental lipid metabolism. Placentas from women ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50626-x

    authors: Hulme CH,Nicolaou A,Murphy SA,Heazell AEP,Myers JE,Westwood M

    更新日期:2019-10-01 00:00:00

  • Comparison of multi echo T2 relaxation and steady state approaches for myelin imaging in the central nervous system.

    abstract::The traditional approach for measuring myelin-associated water with quantitative magnetic resonance imaging (MRI) uses multi-echo T2 relaxation data to calculate the myelin water fraction (MWF). A fundamentally different approach, abbreviated "mcDESPOT", uses a more efficient steady-state acquisition to generate an eq...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-80585-7

    authors: Dvorak AV,Ljungberg E,Vavasour IM,Lee LE,Abel S,Li DKB,Traboulsee A,MacKay AL,Kolind SH

    更新日期:2021-01-14 00:00:00

  • Health-related quality of life amongst people diagnosed with abdominal aortic aneurysm and peripheral artery disease and the effect of fenofibrate.

    abstract::The aims of this study were, firstly, to assess the effect of concurrent peripheral artery disease (PAD) on the health-related quality of life (QOL) of people diagnosed with a small abdominal aortic aneurysm (AAA); and secondly, to test whether the peroxisome proliferator-activated receptor α agonist fenofibrate impro...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71454-4

    authors: Golledge J,Pinchbeck J,Rowbotham SE,Yip L,Jenkins JS,Quigley F,Moxon JV

    更新日期:2020-09-03 00:00:00

  • Cortico-subcortical metabolic correlates of olfactory processing in healthy resting subjects.

    abstract::A wide network of interconnected areas was previously found in neuroimaging studies involving normal as well as pathological subjects; however literature seems to suffer from a lack of investigation in glucose metabolism behaviour under olfactory condition. Thus, the present work describe for the first time a pure olf...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05146

    authors: Alessandrini M,Micarelli A,Chiaravalloti A,Candidi M,Bruno E,Di Pietro B,Schillaci O,Pagani M

    更新日期:2014-06-03 00:00:00

  • Obstetric and perinatal outcomes for twin pregnancies in adolescent girls.

    abstract::This was a nine-year retrospective cohort study to investigate obstetric and perinatal outcomes in a cohort of adolescent girls with twin pregnancies from a major Australian tertiary centre in Brisbane, Australia. The adolescent cohort was aged <19 years and the control group was aged 20-24 years. The total study coho...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-37364-2

    authors: Robson D,Daniels S,Flatley C,Kumar S

    更新日期:2018-12-24 00:00:00

  • Effects of temperature and photosynthetically active radiation on virioplankton decay in the western Pacific Ocean.

    abstract::In this study, we investigated virioplankton decay rates and their responses to changes in temperature and photosynthetically active radiation (PAR) in the western Pacific Ocean. The mean decay rates for total, high-fluorescence, and low-fluorescence viruses were 1.64 ± 0.21, 2.46 ± 0.43, and 1.57 ± 0.26% h-1, respect...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-19678-3

    authors: Wei W,Zhang R,Peng L,Liang Y,Jiao N

    更新日期:2018-01-24 00:00:00

  • Synergistic effect of land-use and vegetation greenness on vulture nestling body condition in arid ecosystems.

    abstract::Climate-driven environmental change and land-use change often interact in their impact on biodiversity, but these interactions have received little scientific attention. Here we study the effects of climate-driven environmental variation (i.e. vegetation greenness) and land-use (protected versus unprotected areas) on ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-31344-2

    authors: Santangeli A,Spiegel O,Bridgeford P,Girardello M

    更新日期:2018-08-29 00:00:00

  • Triggering of eruptions at Axial Seamount, Juan de Fuca Ridge.

    abstract::The submarine volcano Axial Seamount has exhibited an inflation predictable eruption cycle, which allowed for the successful forecast of its 2015 eruption. However, the exact triggering mechanism of its eruptions remains ambiguous. The inflation predictable eruption pattern suggests a magma reservoir pressure threshol...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-67043-0

    authors: Cabaniss HE,Gregg PM,Nooner SL,Chadwick WW Jr

    更新日期:2020-06-23 00:00:00

  • Mitochondrial toxicity and body shape changes during nucleos(t)ide analogues administration in patients with chronic hepatitis B.

    abstract::Our study purpose was to evaluate mitochondrial (mt)DNA and RNA in peripheral blood mononuclear cells (PBMCs) and body shape changes (BSC) in HBV-infected patients. mtDNA and mtRNA were measured in PBMCs. The presence of BSC was evaluated through a questionnaire and clinical evaluation. A total of 157 subjects were en...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/s41598-020-58837-3

    authors: Madeddu G,Fiore V,Melis M,Ortu S,Mannu F,Muredda AA,Garrucciu G,Bandiera F,Zaru S,Bagella P,Calvisi DF,Babudieri S

    更新日期:2020-02-06 00:00:00

  • In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications.

    abstract::Betaine alleviates high-fat diet-induced fatty liver and prenatal betaine programs offspring hepatic lipid metabolism. Excessive corticosterone (CORT) exposure causes fatty liver in chickens, yet it remains unknown whether and how prenatal betaine modulates the susceptibility of CORT-induced fatty liver later in life....

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep40251

    authors: Hu Y,Sun Q,Liu J,Jia Y,Cai D,Idriss AA,Omer NA,Zhao R

    更新日期:2017-01-06 00:00:00

  • Housefly (Musca domestica L.) associated microbiota across different life stages.

    abstract::The housefly (Musca domestica L.) lives in close association with its microbiota and its symbionts are suggested to have pivotal roles in processes such as metabolism and immune response, but it is unclear how the profound physiological changes during ontogeny affect the housefly's associated microbiota and their meta...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-64704-y

    authors: de Jonge N,Michaelsen TY,Ejbye-Ernst R,Jensen A,Nielsen ME,Bahrndorff S,Nielsen JL

    更新日期:2020-05-12 00:00:00

  • A Research on Preparation and Application of the Monolithic Catalyst with Interconnecting Pore Structure.

    abstract::In recent years, the monolithic material has been developed increasingly in the high performance liquid phase field, and it could also be applied in the field of catalyst, as a monolithic catalyst carrier, since it has a large specific surface area, and could be customized based on the mould. The monolithic catalyst i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35021-2

    authors: Tsai SB,Ma H

    更新日期:2018-11-09 00:00:00

  • A tongue for all seasons: extreme phenotypic flexibility in salamandrid newts.

    abstract::Many organisms faced with seasonally fluctuating abiotic and biotic conditions respond by altering their phenotype to account for the demands of environmental changes. Here we discovered that newts, which switch seasonally between an aquatic and terrestrial lifestyle, grow a complex adhesive system on their tongue pad...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00674-y

    authors: Heiss E,Handschuh S,Aerts P,Van Wassenbergh S

    更新日期:2017-04-21 00:00:00

  • Fast ion transport through ultrathin shells of metal sulfide hollow nanocolloids used for high-performance energy storage.

    abstract::Metal sulfide (MS, nickel sulfide/copper sulfide) hollow spheres with hierarchical, ultrathin shell structures have been constructed by a facile method. The as-formed MS hollow structures are shown to be uniform in sizes with hierarchical ultrathin shells, which could facilitate the transport of electrolyte ions. Elec...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-18504-6

    authors: Chen Z,Zhao M,Lv X,Zhou K,Jiang X,Ren X,Mei X

    更新日期:2018-01-08 00:00:00

  • Peri-operative antibiotics acutely and significantly impact intestinal microbiota following bariatric surgery.

    abstract::Bariatric surgery is the most effective treatment for weight loss. Vertical sleeve gastrectomy (VSG) involves the resection of ~ 80% of the stomach and was conceived to purely restrict oral intake. However, evidence suggests more complex mechanisms, particularly postoperative changes in gut microbiota, in facilitating...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-77285-7

    authors: Nalluri H,Kizy S,Ewing K,Luthra G,Leslie DB,Bernlohr DA,Sadowsky MJ,Ikramuddin S,Khoruts A,Staley C,Jahansouz C

    更新日期:2020-11-23 00:00:00

  • Horizontal gene transfer and silver nanoparticles production in a new Marinomonas strain isolated from the Antarctic psychrophilic ciliate Euplotes focardii.

    abstract::We isolated a novel bacterial strain from a prokaryotic consortium associated to the psychrophilic marine ciliate Euplotes focardii, endemic of the Antarctic coastal seawater. The 16S rDNA sequencing and the phylogenetic analysis revealed the close evolutionary relationship to the Antarctic marine bacterium Marinomona...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-66878-x

    authors: John MS,Nagoth JA,Ramasamy KP,Ballarini P,Mozzicafreddo M,Mancini A,Telatin A,Liò P,Giuli G,Natalello A,Miceli C,Pucciarelli S

    更新日期:2020-06-23 00:00:00

  • A Comprehensive Biophysical Analysis of the Effect of DNA Binding Drugs on Protamine-induced DNA Condensation.

    abstract::DNA condensation is a ubiquitous phenomenon in biology, yet the physical basis for it has remained elusive. Here, we have explored the mechanism of DNA condensation through the protamine-DNA interaction, and by examining on it the influence of DNA binding drugs. We observed that the DNA condensation is accompanied by ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41975-8

    authors: Gupta S,Tiwari N,Munde M

    更新日期:2019-04-10 00:00:00

  • Fibronectin synthesis, but not α-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling.

    abstract::During skin healing, periostin facilitates myofibroblast differentiation through a β1 integrin/FAK dependent mechanism and continued expression is associated with scarring. In contrast to skin, gingival tissue does not typically scar upon injury, but the role of periostin in gingival healing has never been investigate...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35805-6

    authors: Kim SS,Nikoloudaki GE,Michelsons S,Creber K,Hamilton DW

    更新日期:2019-02-25 00:00:00