Abstract:
:Many organisms faced with seasonally fluctuating abiotic and biotic conditions respond by altering their phenotype to account for the demands of environmental changes. Here we discovered that newts, which switch seasonally between an aquatic and terrestrial lifestyle, grow a complex adhesive system on their tongue pad consisting of slender lingual papillae and mucus-producing cells to increase the efficiency of prey capture as they move from water onto land. The adhesive system is reduced again as newts switch back to their aquatic stage, where they use suction to capture prey. As suction performance is also enhanced seasonally by reshaping of the mouth due to the growth of labial lobes, our results show that newts are exceptional in exhibiting phenotypic flexibility in two alternating components (i.e. tongue pad and labial lobes) within a single functional system, and suggest that this form of phenotypic flexibility demands complex genetic regulation.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Heiss E,Handschuh S,Aerts P,Van Wassenbergh Sdoi
10.1038/s41598-017-00674-ysubject
Has Abstractpub_date
2017-04-21 00:00:00pages
1006issue
1issn
2045-2322pii
10.1038/s41598-017-00674-yjournal_volume
7pub_type
杂志文章abstract::Insulin resistance is a critical process in the initiation and progression of diabetic nephropathy (DN). Alprostadil (Prostaglandin E1, PGE1) had protective effects on renal function. However, it is unknown whether PGE1 inhibited insulin resistance in renal tubule epithelial cells via autophagy, which plays a protecti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18427-2
更新日期:2018-01-08 00:00:00
abstract::Quantum key agreement is an important topic that the shared key must be negotiated equally by all participants, and any nontrivial subset of participants cannot fully determine the shared key. To date, the embed modes of subkey in all the previously proposed quantum key agreement protocols are based on either BB84 or ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep45046
更新日期:2017-03-23 00:00:00
abstract::During the search for a potent antifungal drug, a cell-permeable metabolite was isolated from a soil isolate taxonomically identified as Penicillium radicum. The strain was found to be a potent antifungal agent. Production conditions of the active compound were optimized and the active compound was isolated, purified,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11948
更新日期:2015-07-10 00:00:00
abstract::The life-like fidelity of organisms captured in amber is unique among all kinds of fossilization and represents an invaluable source for different fields of palaeontological and biological research. One of the most challenging aspects in amber research is the study of traits related to behaviour. Here, indirect eviden...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34352
更新日期:2016-10-04 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) can cause multidimensional cognitive deficits, among which working memory (WM) is usually involved at an early stage. However, the neural substrates underlying impaired WM in T2DM patients are still unclear. To clarify this issue, we utilized functional magnetic resonance imaging (fMRI)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23767
更新日期:2016-03-29 00:00:00
abstract::Angiogenesis is essential in tumor biology and is regulated by vascular endothelial growth factor (VEGF) ligands and receptors. Here we aimed to discover genetic variants associated with levels of circulating angiogenic proteins in cancer patients. Plasma was collected at baseline in 216 pancreatic and 114 colorectal ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34506-4
更新日期:2018-11-05 00:00:00
abstract::All-dielectric nanophotonics lies at a forefront of nanoscience and technology as it allows to control light at the nanoscale using its electric and magnetic components. Bulk silicon does not experience any magnetic response, nevertheless, we demonstrate that the metasurface made of silicon parallelepipeds allows to e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40226-0
更新日期:2019-03-05 00:00:00
abstract::The group-IV tin has been hypothesized to possess intriguing electronic properties in an atom-thick hexagonal form. An attractive pathway of producing sizable 2D crystallites of tin is based on deintercalation of bulk compounds with suitable tin frameworks. Here, we have identified a new synthesizable metal distannide...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28369
更新日期:2016-07-08 00:00:00
abstract::The development of selective visual attention is critical for effectively engaging with an ever-changing world. Its optimal deployment depends upon interactions between neural, motor, and sensory systems across multiple timescales and neurocognitive loci. Previous work illustrates the spatio-temporal dynamics of these...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73187-w
更新日期:2020-10-14 00:00:00
abstract::The effect on the reproductive system and fertility of living in a space environment remains unclear. Here, we caged 12 male mice under artificial gravity (≈1 gravity) (AG) or microgravity (MG) in the International Space Station (ISS) for 35 days, and characterized the male reproductive organs (testes, epididymides, a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50128-w
更新日期:2019-09-24 00:00:00
abstract::Accounting for about 1.5 million deaths annually, lung cancer is the prevailing cause of cancer deaths worldwide, mostly associated with long-term smoking effects. Numerous small-animal studies are performed currently in order to better understand the pathogenesis of the disease and to develop treatment strategies. Wi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00489-x
更新日期:2017-03-24 00:00:00
abstract::There is an urgent need to quantify anthropogenic influence on forest carbon stocks. Using satellite-based radar imagery for such purposes has been challenged by the apparent loss of signal sensitivity to changes in forest aboveground volume (AGV) above a certain 'saturation' point. The causes of saturation are debate...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03469-3
更新日期:2017-06-14 00:00:00
abstract::The pulsed events of rainstorm erosion on the Loess Plateau are well-known, but little information is available concerning the characteristics of superficial soil erosion processes caused by heavy rainstorms at the watershed scale. This study statistically evaluated characteristics of pulsed runoff-erosion events base...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22045-x
更新日期:2018-02-27 00:00:00
abstract::Study of knockout (KO) mice has helped understand the link between many genes/proteins and human diseases. Identification of infertile KO mice provides valuable tools to characterize the molecular mechanisms underlying gamete formation. The KIAA0319L gene has been described to have a putative association with dyslexia...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28666-6
更新日期:2018-07-10 00:00:00
abstract::During recent military operations, eye-related injuries have risen in frequency due to increased use of explosive weaponry which often result in corneal puncture injuries. These have one of the poorest visual outcomes for wounded soldiers, often resulting in blindness due to the large variations in injury shape, size,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61079-y
更新日期:2020-03-06 00:00:00
abstract::This study investigated the effects of 4 aeration levels (varied by injection of air to the soil through subsurface irrigation lines) at two subsurface irrigation line depths (15 and 40 cm) on plant growth, yield and nutritional quality of greenhouse tomato. In all experiments, fruit number, width and length, yield, v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39307
更新日期:2016-12-20 00:00:00
abstract::Event-free survival (EFS) is considered the most reliable surrogate endpoint for overall survival (OS) in randomised controlled trials (RCTs) of adjuvant therapies for malignant tumours. However, the surrogacy of intermediate endpoints such as EFS for OS in trials of patients with osteosarcoma has not been investigate...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-020-65591-z
更新日期:2020-05-22 00:00:00
abstract::The roles of CD4 + T cells and CD8 + T cells in hepatitis B virus (HBV) infection have been well documented. However, the role of innate immunity in HBV infection remains obscure. Here we examined the effect of activation of innate immunity by polyinosinic: polycytidylic acid (PolyI:C) on HBV infection. A chronic HBV ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00387-2
更新日期:2017-03-22 00:00:00
abstract::Peatlands perform important ecosystem functions, such as carbon storage and nutrient retention, which are affected, among other factors, by vegetation and peat decomposition. The availability of silicon (Si) in peatlands differs strongly, ranging from <1 to >25 mg L-1. Since decomposition of organic material was recen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09130-3
更新日期:2017-08-18 00:00:00
abstract::This work considers the effects of the Hurst exponent (H) on the local electric field distribution and the slope of the Fowler-Nordheim (FN) plot when considering the cold field electron emission properties of rough Large-Area Conducting Field Emitter Surfaces (LACFESs). A LACFES is represented by a self-affine Weiers...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10175
更新日期:2015-06-02 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is an increasing health problem worldwide, with genetic, epigenetic, and environmental components. Here, we describe the first example of NAFLD caused by genetic disruption of a mammalian potassium channel subunit. Mice with germline deletion of the KCNE2 potassium channel β su...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23118
更新日期:2016-03-17 00:00:00
abstract::Double quantum dots (DQDs) are a versatile platform for solid-state physics, quantum computation and nanotechnology. The micro-fabrication techniques commonly used to fabricate DQDs are difficult to extend to the atomic scale. Using an alternative approach, which relies on scanning tunneling microscopy and spectroscop...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10814-z
更新日期:2017-09-07 00:00:00
abstract::Understanding the drivers of animal movement is significant for ecology and biology. Yet researchers have so far been unable to fully understand these drivers, largely due to low data resolution. In this study, we analyse a high-frequency movement dataset for a group of grazing cattle and investigate their spatiotempo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31967
更新日期:2016-08-24 00:00:00
abstract::Chronic kidney disease (CKD) patients have many affected physiological pathways. Variations in the genes regulating these pathways might affect the incidence and predisposition to this disease. A total of 722 Spanish adults, including 548 patients and 174 controls, were genotyped to better understand the effects of ge...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56695-2
更新日期:2020-01-10 00:00:00
abstract::Here, we assessed the sulfated derivative of the microbial polysaccharide gellan gum and derivatives of λ and κ-carrageenans for their ability to inhibit Plasmodium falciparum 3D7 and Dd2 growth and invasion of red blood cells in vitro. Growth inhibition was assessed by means of flow cytometry after a 96-h exposure to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04723
更新日期:2014-04-17 00:00:00
abstract::We report a modified two-dimensional Cherenkov radiation, which occurs on a high-index dielectric nano-film driven by uniformly moving electron-beam. It is essentially different from the ordinary Cherenkov radiation in that, in the nondispersive medium, it shows unique dispersion characteristics-the waves with higher ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06176-1
更新日期:2017-07-19 00:00:00
abstract::Upon illumination, a dielectric microsphere (μS) can generate a photonic nanojet (PNJ), which plays a role in the super-resolution imaging of a sample placed in the μS's immediate proximity. Recent microscopy implementations pioneered this concept but, despite the experimental characterization and theoretical modeling...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33604-7
更新日期:2018-10-12 00:00:00
abstract::Phytoene desaturases catalyse from two to six desaturation reactions on phytoene, generating a large diversity of molecules that can then be cyclised and produce, depending on the organism, many different carotenoids. We constructed a phylogenetic tree of a subset of phytoene desaturases from the CrtI family for which...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77876-4
更新日期:2020-12-03 00:00:00
abstract::Applying a circular economy approach, this research explores the use of cheese whey permeate (CWP), by-product of whey ultrafiltration, as cheap substrate for the production of bacterial cellulose (BC) and Sakacin-A, to be used in an antimicrobial packaging material. BC from the acetic acid bacterium Komagataeibacter ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78430-y
更新日期:2020-12-07 00:00:00
abstract::We investigated high-efficiency two-terminal tandem photovoltaic (PV) devices consisting of a p/i/n thin film silicon top sub-cell (p/i/n-TFS) and a heterojunction with an intrinsic thin-layer (HIT) bottom sub-cell. We used computer simulations and experimentation. The short-circuit current density (Jsc) of the top su...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33734-y
更新日期:2018-10-18 00:00:00