Elevated plasma abscisic acid is associated with asymptomatic falciparum malaria and with IgG-/caspase-1-dependent immunity in Plasmodium yoelii-infected mice.

abstract：:A high level of plasma low-density lipoprotein (LDL) cholesterol is considered a risk factor for atherosclerosis. Because the hepatic LDL receptor (LDLR) is essential for clearing plasma LDL cholesterol, activation of LDLR is a promising therapeutic target for patients with atherosclerotic disease. Here we demonstrate...

journal_title：Scientific reports

authors： Ochiai A,Miyata S,Iwase M,Shimizu M,Inoue J,Sato R

更新日期：2016-04-25 00:00:00

abstract：:Music and language are complex hierarchical systems in which individual elements are systematically combined to form larger, syntactic structures. Suggestions that music and language share syntactic processing resources have relied on evidence that syntactic violations in music interfere with syntactic processing in l...

journal_title：Scientific reports

authors： Fiveash A,McArthur G,Thompson WF

更新日期：2018-12-17 00:00:00

abstract：:The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. P. falciparum strains Dd2 and W2mef have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neu...

journal_title：Scientific reports

authors： Awandare GA,Nyarko PB,Aniweh Y,Ayivor-Djanie R,Stoute JA

更新日期：2018-04-10 00:00:00

abstract：:The diversity of DNA sequencing methods and algorithms for genome assemblies presents scientists with a bewildering array of choices. Here, we construct and compare eight candidate assemblies combining overlapping shotgun read data, mate-pair and Chicago libraries and four different genome assemblers to produce a high...

journal_title：Scientific reports

authors： Fernandez-Silva I,Henderson JB,Rocha LA,Simison WB

更新日期：2018-01-24 00:00:00

abstract：:Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of SHP-2 have been foun...

journal_title：Scientific reports

authors： Shim SY,Jeong HJ,Park HJ,Kwon EY,Kim BM,Choi YJ,Choi YH,Cho SJ,Choi JH,Park EA

更新日期：2017-07-20 00:00:00

abstract：:Wnt/β-catenin signalling plays a prominent role in maintaining self-renewal and pluripotency of mouse embryonic stem cells (mESCs). microRNAs (miRNAs) have critical roles in maintaining pluripotency and directing reprogramming. To investigate the effect of GSK3 inhibitors on miRNA expression, we analysed the miRNA exp...

journal_title：Scientific reports

authors： Wu Y,Liu F,Liu Y,Liu X,Ai Z,Guo Z,Zhang Y

更新日期：2015-03-02 00:00:00

abstract：:Wrist worn raw-data accelerometers are used increasingly in large-scale population research. We examined whether sleep parameters can be estimated from these data in the absence of sleep diaries. Our heuristic algorithm uses the variance in estimated z-axis angle and makes basic assumptions about sleep interruptions. ...

journal_title：Scientific reports

authors： van Hees VT,Sabia S,Jones SE,Wood AR,Anderson KN,Kivimäki M,Frayling TM,Pack AI,Bucan M,Trenell MI,Mazzotti DR,Gehrman PR,Singh-Manoux BA,Weedon MN

更新日期：2018-08-28 00:00:00

abstract：:A low-cost compact planar leaky-wave antenna (LWA) is proposed offering directive broadside radiation over a significantly wide bandwidth. The design is based on an annular metallic strip grating (MSG) configuration, placed on top of a dual-layer grounded dielectric substrate. This defines a new two-layer parallel-pla...

journal_title：Scientific reports

authors： Comite D,Podilchak SK,Baccarelli P,Burghignoli P,Galli A,Freundorfer AP,Antar YMM

更新日期：2018-12-10 00:00:00

abstract：:The influenza virus neuraminidase (NA) is essential for the virus life cycle. The rise of resistance mutations against current antiviral therapies has increased the need for the development of novel inhibitors. Recent efforts have targeted a cavity adjacent to the catalytic site (the 150-cavity) in addition to the pri...

journal_title：Scientific reports

authors： Kerry PS,Mohan S,Russell RJ,Bance N,Niikura M,Pinto BM

更新日期：2013-10-16 00:00:00

abstract：:Curvature components derived from satellite gravity gradients provide new global views of Earth's structure. The satellite gravity gradients are based on the GOCE satellite mission and we illustrate by curvature images how the Earth is seen differently compared to seismic imaging. Tectonic domains with similar seismic...

journal_title：Scientific reports

authors： Ebbing J,Haas P,Ferraccioli F,Pappa F,Szwillus W,Bouman J

更新日期：2018-11-05 00:00:00

abstract：:A key challenge of central nervous system tumor surgery is to discriminate between brain regions infiltrated by tumor cells and surrounding healthy tissue. Although monitoring of autofluorescence could potentially be an efficient way to provide reliable information for these regions, we found little information on thi...

journal_title：Scientific reports

authors： Poulon F,Mehidine H,Juchaux M,Varlet P,Devaux B,Pallud J,Abi Haidar D

更新日期：2017-10-25 00:00:00

abstract：:This article presents a study whose purpose is to elucidate the damage effects in thin films on their magnetic response. Co40Fe40B20 and Ni80Fe20 films of different nanometric thicknesses were stretched by more than 10% and in situ probed by atomic force microscopy measurements to determine their irreversible mechanic...

journal_title：Scientific reports

authors： Merabtine S,Zighem F,Garcia-Sanchez A,Gunasekaran V,Belmeguenai M,Zhou X,Lupo P,Adeyeye AO,Faurie D

更新日期：2018-09-12 00:00:00

abstract：:Dengue virus infection is a global threat for which no specific treatment has not been established. Previous reports suggested chrysin and flavanone derivatives were potential flaviviral inhibitors. Here, we reported two halogenated chrysins, abbreviated FV13 and FV14, were highly potent against DENV1-4 and ZIKV infec...

journal_title：Scientific reports

authors： Suroengrit A,Yuttithamnon W,Srivarangkul P,Pankaew S,Kingkaew K,Chavasiri W,Boonyasuppayakorn S

更新日期：2017-10-20 00:00:00

abstract：:Clobetasol propionate (CLO) is a potent glucocorticoid used to treat inflammation-based skin, scalp, and hair disorders. In such conditions, hair follicles (HF) are not only the target site but can also act as drug reservoirs when certain formulations are topically applied. Recently, we have demonstrated nanostructure...

journal_title：Scientific reports

authors： Angelo T,El-Sayed N,Jurisic M,Koenneke A,Gelfuso GM,Cunha-Filho M,Taveira SF,Lemor R,Schneider M,Gratieri T

更新日期：2020-01-13 00:00:00

abstract：:Age and sleep both affect emotional functioning. Since sleep patterns change over the lifespan, we investigated the effects of short sleep and age on empathic responses. In a randomized cross-over experimental design, healthy young and older volunteers (n = 47 aged 20-30 years and n = 39 aged 65-75 years) underwent fu...

journal_title：Scientific reports

authors： Tamm S,Nilsonne G,Schwarz J,Lamm C,Kecklund G,Petrovic P,Fischer H,Åkerstedt T,Lekander M

更新日期：2017-09-25 00:00:00

abstract：:Adverse events during the prenatal and early postnatal period of life are associated with development of cardiovascular disease in adulthood. Prenatal exposure to excess testosterone (T) in sheep induces adverse reproductive and metabolic programming leading to polycystic ovarian syndrome, insulin resistance and hyper...

journal_title：Scientific reports

authors： Vyas AK,Hoang V,Padmanabhan V,Gilbreath E,Mietelka KA

更新日期：2016-06-22 00:00:00

abstract：:In the Brown et al. study 'Increased food supply mitigates ocean acidification effects on calcification but exacerbates effects on growth' they show disagreement with the tested hypothesis and data analysis methodology used in our 2016 study. We acknowledge careful criticism and a constructive dialogue are necessary t...

journal_title：Scientific reports

authors： Ramajo L,Hendriks IE,Lagos NA,Krause-Jensen D,Marbà N,Sejr MK,Duarte CM

更新日期：2018-06-28 00:00:00

abstract：:An accurate knowledge of tissue optical properties (absorption coefficients, μa, and reduced scattering coefficients, μs') is critical for precise modeling of light propagation in biological tissue, essential for developing diagnostic and therapeutic optical techniques that utilize diffusive photons. A great number of...

journal_title：Scientific reports

authors： Hoshi Y,Tanikawa Y,Okada E,Kawaguchi H,Nemoto M,Shimizu K,Kodama T,Watanabe M

更新日期：2019-06-24 00:00:00

abstract：:The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation of sec59-1 caused a protein N-glycosylation defect mediated ER stress resulting in increa...

journal_title：Scientific reports

authors： William James A,Ravi C,Srinivasan M,Nachiappan V

更新日期：2019-10-09 00:00:00

abstract：:This study aimed to design and functionally characterize peptide mimetics of the nanobody (Nb) related to the β2-adrenergic receptor (β2-AR) (nanobody-derived peptide, NDP). We postulated that the computationally derived and optimized complementarity-determining region 3 (CDR3) of Nb is sufficient for its interaction ...

journal_title：Scientific reports

authors： Sencanski M,Glisic S,Šnajder M,Veljkovic N,Poklar Ulrih N,Mavri J,Vrecl M

更新日期：2019-11-12 00:00:00

abstract：:Glioblastoma (grade IV glioma) is the most common and aggressive adult brain tumor. A better understanding of the biology of glioblastoma cells is crucial to identify molecular targets stimulating cell death. NPM1 (nucleophosmin) is a multifunctional chaperone that plays an important role in cancer development. Herein...

journal_title：Scientific reports

authors： Holmberg Olausson K,Elsir T,Moazemi Goudarzi K,Nistér M,Lindström MS

更新日期：2015-11-12 00:00:00

abstract：:This study presents, attenuated total reflection Fourier transforms infrared spectroscopy of dried serum samples in an effort to assess biochemical changes induced by non-Hodgkin's lymphoma and subcutaneous melanoma. An EL4 mouse model of non-Hodgkin lymphoma and a B16 mouse model of subcutaneous melanoma are used to ...

journal_title：Scientific reports

authors： Ghimire H,Venkataramani M,Bian Z,Liu Y,Perera AGU

更新日期：2017-12-05 00:00:00

abstract：:Targeted protein degradation (TPD) through a proteasome-dependent pathway induced by heterofunctional small molecules is initiated by the formation of a ternary complex with recruited E3 ligases. This complex formation affects the degradation ability of TPD molecules, and thus we tested for visualization of the intrac...

journal_title：Scientific reports

authors： Kaji T,Koga H,Kuroha M,Akimoto T,Hayata K

更新日期：2020-02-20 00:00:00

abstract：:Three-dimensionally (3D) porous morphology of nanostructures can effectively improve their electrocatalytic activity and durability for various electrochemical reactions owing to big surface area and interconnected structure. Cyanogel, a jelly-like inorganic polymer, can be used to synthesize various three-dimensional...

journal_title：Scientific reports

authors： Liu X,Xu G,Chen Y,Lu T,Tang Y,Xing W

更新日期：2015-01-05 00:00:00

abstract：:The physical mechanism of the anthropogenic triggering of large earthquakes on active faults is studied on the basis of experimental phenomenology, i.e., that earthquakes occur on active tectonic faults, that crustal stress values are those measured in situ and, on active faults, comply to the values of the stress dro...

journal_title：Scientific reports

authors： Mulargia F,Bizzarri A

更新日期：2014-08-26 00:00:00

abstract：:The myogenic factor MyoD regulates skeletal muscle differentiation by interacting with a variety of chromatin-modifying complexes. Although MyoD can induce and maintain chromatin accessibility at its target genes, its binding and trans-activation ability can be limited by some types of not fully characterized epigenet...

journal_title：Scientific reports

authors： Matteini F,Andresini O,Petrai S,Battistelli C,Rossi MN,Maione R

更新日期：2020-09-15 00:00:00

abstract：:A new method combining aqueous solution printing with UV Laser crystallization (UVLC) and post annealing is developed to deposit highly transparent and conductive Aluminum doped Zinc Oxide (AZO) films. This technique is able to rapidly produce large area AZO films with better structural and optoelectronic properties t...

journal_title：Scientific reports

authors： Nian Q,Callahan M,Saei M,Look D,Efstathiadis H,Bailey J,Cheng GJ

更新日期：2015-10-30 00:00:00

abstract：:Sealed-bid auction is an important tool in modern economic especially concerned with networks. However, the bidders still lack the privacy protection in previously proposed sealed-bid auction schemes. In this paper, we focus on how to further protect the privacy of the bidders, especially the non-winning bidders. We f...

journal_title：Scientific reports

authors： Shi RH,Zhang M

更新日期：2019-05-20 00:00:00

abstract：:The present study investigated the effect of acute stress on attentional bias to threat using behavioral and ERP methods. Sixty-two male participants were randomly assigned to a stress condition (Trier Social Stress Test) or a control condition. To examine the impact of stress-induced cortisol on attentional bias to t...

journal_title：Scientific reports

authors： Jiang C,Buchanan TW,Yao Z,Zhang K,Wu J,Zhang L

更新日期：2017-11-06 00:00:00

abstract：:Infrared detection devices are becoming miniature with micro or nano-scale size. The advantages of downsizing come on the expense of insufficient collection of infrared radiation. Therefore, utilizing nano-plasmonic optical antennas becomes mandatory. However, it is desirable to develop antennas with broad bandwidth, ...

journal_title：Scientific reports

authors： Awad E

更新日期：2019-08-21 00:00:00