Glycine triggers a non-ionotropic activity of GluN2A-containing NMDA receptors to confer neuroprotection.

abstract：:Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane. Loss of Caveolin-1 (Cav1) function in mice causes distinct neurological phenotypes leading to impaired motor control, however, the underlying developmental mechanisms are largely unknown. In...

journal_title：Scientific reports

authors： Breuer M,Berger H,Borchers A

更新日期：2020-10-05 00:00:00

abstract：:Pluripotency can be induced in vitro from adult somatic mammalian cells by enforced expression of defined transcription factors regulating and initiating the pluripotency network. Despite the substantial advances over the last decade to improve the efficiency of direct reprogramming, exact mechanisms underlying the co...

journal_title：Scientific reports

authors： Raab S,Klingenstein M,Möller A,Illing A,Tosic J,Breunig M,Kuales G,Linta L,Seufferlein T,Arnold SJ,Kleger A,Liebau S

更新日期：2017-11-29 00:00:00

abstract：:Activation of different slip systems in hexagonal close packed (h.c.p.) metals depends primarily on the c/a ratio, which is an intrinsic property that can be altered through alloying addition. In conventional h.c.p. alloys where there is no diffusion-less phase transformation and associated transformation volume chang...

journal_title：Scientific reports

authors： Sinha S,Nene SS,Frank M,Liu K,Agrawal P,Mishra RS

更新日期：2019-09-12 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Zhou G,Zhu Y,Yin Y,Su M,Li M

更新日期：2018-03-22 00:00:00

abstract：:The prognostic factors for survival among patients with secondary osteosarcoma remain unclear. The aim of this study was to develop a practical nomogram for predicting cancer-specific survival (CSS) in patients with osteosarcoma as a secondary malignancy. The surveillance, epidemiology, and end results database was us...

journal_title：Scientific reports

authors： He Y,Liu H,Wang S,Zhang J

更新日期：2020-07-30 00:00:00

abstract：:Local and global changes associated with anthropogenic activities are impacting marine and terrestrial ecosystems. Macroalgae, especially habitat-forming species like kelp, play critical roles in temperate coastal ecosystems. However, their abundance and distribution patterns have been negatively affected by warming i...

journal_title：Scientific reports

authors： Fernández PA,Gaitán-Espitia JD,Leal PP,Schmid M,Revill AT,Hurd CL

更新日期：2020-02-21 00:00:00

abstract：:Soil components (e.g., clays, bacteria and humic substances) are known to produce mineral-organic composites in natural systems. Herein, batch sorption isotherms, isothermal titration calorimetry (ITC), and Cd K-edge EXAFS spectroscopy were applied to investigate the binding characteristics of Cd on montmorillonite(Mo...

journal_title：Scientific reports

authors： Du H,Chen W,Cai P,Rong X,Dai K,Peacock CL,Huang Q

更新日期：2016-01-21 00:00:00

abstract：:The primary hurdle for diagnosis of some diseases is the long incubation required to culture and confirm the presence of bacteria. The concept of using microbial VOCs as "signature markers" could provide a faster and noninvasive diagnosis. Finding biomarkers is challenging due to the specificity required in complex ma...

journal_title：Scientific reports

authors： Maurer DL,Ellis CK,Thacker TC,Rice S,Koziel JA,Nol P,VerCauteren KC

更新日期：2019-08-20 00:00:00

abstract：:Near infrared (NIR) fluorophores like Pt-porphyrin along with analyte specific enzymes require co-encapsulation in biocompatible and biodegradable carriers in order to be transformed into implantable biosensors for efficient and continuous monitoring of analytes in patients. The main objective of this research is to d...

journal_title：Scientific reports

authors： Pandey G,Chaudhari R,Joshi B,Choudhary S,Kaur J,Joshi A

更新日期：2019-03-22 00:00:00

abstract：:Although intestinal trefoil factor (ITF) can alleviate the burn-induced intestinal mucosa injury, the underlying mechanisms remains elusive. In this study, we investigated if ITF alters glutamine transport on the brush border membrane vesicles (BBMVs) of the intestines in Sprague-Dawley rats inflicted with 30% TBSA an...

journal_title：Scientific reports

authors： Hu J,Shi Y,Wang C,Wan H,Wu D,Wang H,Peng X

更新日期：2018-02-16 00:00:00

abstract：:A crystal of emerging magnetic charges is expected in the phase diagram of the dipolar kagomé spin ice. An observation of charge crystallites in thermally demagnetized artificial spin ice arrays has been recently reported by S. Zhang and coworkers and explained through the thermodynamics of the system as it approaches...

journal_title：Scientific reports

authors： Montaigne F,Lacour D,Chioar IA,Rougemaille N,Louis D,Mc Murtry S,Riahi H,Burgos BS,Menteş TO,Locatelli A,Canals B,Hehn M

更新日期：2014-07-16 00:00:00

abstract：:The pectin methylesterase action is usually studied in a homogeneous aqueous medium in the presence of a large excess of soluble substrate and water. However in the cell wall, the water content is much lower, the substrate is cross-linked with itself or with other polymers, and the enzyme has to diffuse through the so...

journal_title：Scientific reports

authors： Bonnin E,Alvarado C,Crépeau MJ,Bouchet B,Garnier C,Jamme F,Devaux MF

更新日期：2019-08-29 00:00:00

abstract：:Exposure to light at night (LAN) is associated with insomnia in humans. Light provides the main input to the master clock in the hypothalamic suprachiasmatic nucleus (SCN) that coordinates the sleep-wake cycle. We aimed to develop a rodent model for the effects of LAN on sleep. Therefore, we exposed male Wistar rats t...

journal_title：Scientific reports

authors： Stenvers DJ,van Dorp R,Foppen E,Mendoza J,Opperhuizen AL,Fliers E,Bisschop PH,Meijer JH,Kalsbeek A,Deboer T

更新日期：2016-10-20 00:00:00

abstract：:The modern Asian monsoonal systems are currently believed to have originated around the end of the Oligocene following a crucial step of uplift of the Tibetan-Himalayan highlands. Although monsoon possibly drove the evolution of many mammal lineages during the Neogene, no evidence thereof has been provided so far. We ...

journal_title：Scientific reports

authors： López-Antoñanzas R,Knoll F,Wan S,Flynn LJ

更新日期：2015-03-11 00:00:00

abstract：:New clinical trials for diabetic macular oedema (DMO) are being designed to prove superiority over aflibercept when this agent is already very effective in improving visual acuity (VA) and DMO. The aim of this study was to determine the optimal inclusion-exclusion criteria for trials to aim for superiority in visual o...

journal_title：Scientific reports

authors： Halim S,Gurudas S,Chandra S,Greenwood J,Sivaprasad S

更新日期：2020-10-05 00:00:00

abstract：:Formic acid (FA) has been used for decades to control Varroa destructor, one of the most important parasites of the western honey bee, Apis mellifera. The rather unselective molecular mode of action of FA and its possible effects on honeybees have long been a concern of beekeepers, as it has undesirable side effects t...

journal_title：Scientific reports

authors： Genath A,Sharbati S,Buer B,Nauen R,Einspanier R

更新日期：2020-12-14 00:00:00

abstract：:Zika virus (ZIKV) is an arboviral infection that has been shown to be sexually transmitted. The study outlined herein aims to determine if accessory sex glands and epididymal epithelial cells are sources of viral persistence in subacute and chronic ZIKV infection, and if infection of these organs is important in sexua...

journal_title：Scientific reports

authors： Clancy CS,Van Wettere AJ,Morrey JD,Julander JG

更新日期：2019-06-06 00:00:00

abstract：:Highly Tm(3+) doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm(3+) doped barium gallo-germanate (BGG) glasses....

journal_title：Scientific reports

authors： Wen X,Tang G,Yang Q,Chen X,Qian Q,Zhang Q,Yang Z

更新日期：2016-02-01 00:00:00

abstract：:Three dimensional single particle trapping and manipulation is an outstanding challenge in various fields ranging from basic physics to life sciences. By monitoring the response of a trapped particle to a designed environment one can extract its characteristics. In addition, quantum dynamics of a spatially scanned wel...

journal_title：Scientific reports

authors： Kayci M,Radenovic A

更新日期：2015-11-12 00:00:00

abstract：:Biomimetic scales provide a convenient template to tailor the bending stiffness of the underlying slender substrate due to their mutual sliding after engagement. Scale stiffness can therefore directly impact the substrate behavior, opening a potential avenue for substrate stiffness tunability. Here, we have developed ...

journal_title：Scientific reports

authors： Tatari M,Kamrava S,Ghosh R,Nayeb-Hashemi H,Vaziri A

更新日期：2020-10-13 00:00:00

abstract：:SNPs, abundant in human genome with lower mutation rate, are attractive to genetic application like forensic, anthropological and evolutionary studies. Universal SNPs showing little allelic frequency variation among populations while remaining highly informative for human identification were obtained from previous stu...

journal_title：Scientific reports

authors： Zhang S,Bian Y,Zhang Z,Zheng H,Wang Z,Zha L,Cai J,Gao Y,Ji C,Hou Y,Li C

更新日期：2015-12-22 00:00:00

abstract：:Three dimensional hierarchical nanostructures have attracted great attention for electrochemical energy storage applications. In this work, self-supported TiO2@Ni(OH)2 core-shell nanowire arrays are prepared on carbon fiber paper via the combination of hydrothermal synthesis and chemical bath deposition. In this core-...

journal_title：Scientific reports

authors： Ke Q,Zheng M,Liu H,Guan C,Mao L,Wang J

更新日期：2015-09-10 00:00:00

abstract：:This study investigated the effect of various prebiotics (indigestible dextrin, α-cyclodextrin, and dextran) on human colonic microbiota at a dosage corresponding to a daily intake of 6 g of prebiotics per person (0.2% of dietary intake). We used an in vitro human colonic microbiota model based on batch fermentation s...

journal_title：Scientific reports

authors： Sasaki D,Sasaki K,Ikuta N,Yasuda T,Fukuda I,Kondo A,Osawa R

更新日期：2018-01-11 00:00:00

abstract：:The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites ...

journal_title：Scientific reports

authors： Nor NSM,Yip CW,Ibrahim N,Jaafar MH,Rashid ZZ,Mustafa N,Hamid HHA,Chandru K,Latif MT,Saw PE,Lin CY,Alhasa KM,Hashim JH,Nadzir MSM

更新日期：2021-01-28 00:00:00

abstract：:High mobility channel thin-film-transistor (TFT) is crucial for both display and future generation integrated circuit. We report a new metal-oxide TFT that has an ultra-thin 4.5 nm SnO2 thickness for both active channel and source-drain regions, very high 147 cm(2)/Vs field-effect mobility, high ION/IOFF of 2.3 × 10(7...

journal_title：Scientific reports

authors： Shih CW,Chin A,Lu CF,Su WF

更新日期：2016-01-08 00:00:00

abstract：:Technical advances including liquid chromatography-tandem mass spectrometry and its data analysis enable detailed proteomic analysis of the nasal mucus. Alterations of the nasal mucus proteome may provoke substantial changes of the nasal physiology and have already been associated with rhinologic diseases such as alle...

journal_title：Scientific reports

authors： Wolf A,Liesinger L,Spoerk S,Schittmayer M,Lang-Loidolt D,Birner-Gruenberger R,Tomazic PV

更新日期：2018-12-03 00:00:00

abstract：:Glassy carbon electrode (GCE) was modified with metal oxides (MO = Fe3O4, ZnO) nanoparticles doped phthalocyanine (Pc) and functionalized MWCNTs, and the electrocatalytic properties were studied. Successful synthesis of the metal oxide nanoparticles and the MO/Pc/MWCNT composite were confirmed using FTIR, Raman and SE...

journal_title：Scientific reports

authors： Mphuthi NG,Adekunle AS,Ebenso EE

更新日期：2016-06-01 00:00:00

abstract：:Studies suggest that semen quality is declining globally, however, the debate remains open due to the possible effects of ethnic and geographical differences. This study aimed to explore whether semen quality of sperm donor candidates has changed in Henan Province, China from 2009 to 2019. In this retrospective study,...

journal_title：Scientific reports

authors： Liu J,Dai Y,Li Y,Yuan E,Wang Q,Wang X,Guan Y

更新日期：2020-07-01 00:00:00

abstract：:Previous experimental studies discovered universal growth of chains and nanowires of various chemical elements on a corrugated molecular network of Cu3N on the Cu(110). Herein, performing combined ab initio and quantum Hamiltonian studies we demonstrate that such chains can be used for a fast spin switching and entang...

journal_title：Scientific reports

authors： Sivkov IN,Bazhanov DI,Stepanyuk VS

更新日期：2017-06-05 00:00:00

abstract：:Predicting the occurrence of ventricular tachyarrhythmia (VTA) in advance is a matter of utmost importance for saving the lives of cardiac arrhythmia patients. Machine learning algorithms have been used to predict the occurrence of imminent VTA. In this study, we used a one-dimensional convolutional neural network (1-...

journal_title：Scientific reports

authors： Taye GT,Hwang HJ,Lim KM

更新日期：2020-04-21 00:00:00