A close look at axonal transport: Cargos slow down when crossing stationary organelles.

abstract：:The distribution of neurons containing the messenger RNA encoding preprotachykinin, the precursor of the neuropeptides substance P and K, was examined in the striatum of the rat. The large majority of cells densely labelled by in situ hybridization histochemistry (using a 35S-radiolabelled RNA probe complementary of t...

journal_title：Neuroscience letters

authors： Chesselet MF,Robbins E

更新日期：1989-01-02 00:00:00

abstract：:Human sweat and sebaceous glands were studied immunohistochemically with a monoclonal antibody recognizing a vasoactive intestinal polypeptide (VIP) receptor. The staining pattern correlated well with the known distribution of sympathetic VIP-containing nerves in the human skin. The luminal cell layer of the sweat gla...

journal_title：Neuroscience letters

authors： Kummer W,Herbst WM,Heym C

更新日期：1990-03-14 00:00:00

abstract：:The effects of caloric restriction (CR) on cognition and behavior in developing mice were investigated in this study. Male and female Kunmin mice were fed a standard rodent diet ad libitum (Control); 80% of control (20% CR) or 65% of control (35% CR) for 6 months. Body weight gain was significant reduced in CR mice re...

journal_title：Neuroscience letters

authors： Wu A,Sun X,Liu Y

更新日期：2003-03-20 00:00:00

abstract：:Our previous investigations revealed that progranulin (PGRN) is a lysosomal protein involved in hippocampal neurogenesis and neuroinflammation. However, the possible involvement of PGRN in regulating inflammatory response and mediating neuronal activity is still not well-defined. Here, we demonstrate that PGRN deficie...

journal_title：Neuroscience letters

authors： Bai D,Ma Y,Lv L,Wang Y,Yang W,Ma Y

更新日期：2020-02-16 00:00:00

abstract：:The transcriptional regulation of the gene encoding α-synuclein (SNCA) is thought to play a critical role in the pathogenesis of Parkinson's disease (PD), as common genetic variability in this gene is associated with an elevated risk of developing PD. However, the relevant mechanisms are still poorly understood. So fa...

journal_title：Neuroscience letters

authors： Brenner S,Wersinger C,Gasser T

更新日期：2015-07-10 00:00:00

abstract：:The dopamine system in the limbic-prefrontal cortex has been assumed to play an important role in the cognitive dysfunction of schizophrenia and phencyclidine (PCP)-induced psychosis. In the present study, the role of metabotropic glutamate (mGlu) receptor subtypes on PCP-induced cortical dopamine release was investig...

journal_title：Neuroscience letters

authors： Maeda J,Suhara T,Okauchi T,Semba J

更新日期：2003-01-23 00:00:00

abstract：:The Amphibalanus amphitrite barnacle is a sessile marine crustacean and a major constituent of benthic as well as intertidal communities. A. amphitrite is also an important component of biofouling on artificial substrates. The role of nitric oxide (NO) was recently observed in the settlement of this species. In this w...

journal_title：Neuroscience letters

authors： Gallus L,Ferrando S,Gambardella C,Faimali M,Piazza V,Masini MA

更新日期：2013-10-25 00:00:00

abstract：:The objective of the present study was to determine differences in neural networks between expert and novice archers during an archery pre-performance routine period (PPR). The experiment was conducted with eight world-class competitor or Olympic medalist archers and eight novices. In the experiment, the task was to s...

journal_title：Neuroscience letters

authors： Kim J,Lee HM,Kim WJ,Park HJ,Kim SW,Moon DH,Woo M,Tennant LK

更新日期：2008-11-21 00:00:00

abstract：:Following unilateral transection of the medial forebrain bundle (MFB) within the anterior hypothalamic-preoptic region of cats, the biting attack upon a rat elicited by ipsilateral posterior hypothalamic or ventral midbrain stimulation is eliminated, although the cat continues to approach from 2.8 metres away to withi...

journal_title：Neuroscience letters

authors： Halliday R,Bandler R

更新日期：1981-01-20 00:00:00

abstract：:Nerve growth factor (NGF) was injected in the brain of neonatal rats. In eleven of thirty-one rats that received 1 microgram of mouse NGF (2.5S form) on postnatal day 3, NGF receptor-like immunoreactivity was found in the preoptic area (POA) and hypothalamus until 12 days after birth. However, no immunoreactivity was ...

journal_title：Neuroscience letters

authors： Nishizuka M,Arai Y

更新日期：1992-04-27 00:00:00

abstract：:Within the normal inner ear, there are elements that belong to the immune system. Different inner ear disorders can be explained by autoimmune mechanisms, affecting both humoral and cellular immunity. Melatonin, the principal hormone of the pineal gland, modulates the immune system and extensively participates in the ...

journal_title：Neuroscience letters

authors： Lopez-Gonzalez MA,Guerrero JM,Delgado F

更新日期：1997-11-28 00:00:00

abstract：:The distribution and cellular localisation of somatostatin receptor subtype 4 (SSTR4) was investigated in the adult rat brain using the technique of in situ hybridisation with subtype specific oligonucleotide probes. Somatostatin receptor subtype 4 was found mainly in the hippocampus CA1 > CA2 > CA3 pyramidal cells an...

journal_title：Neuroscience letters

authors： Harrington KA,Schindler M,Humphrey PP,Emson PC

更新日期：1995-03-16 00:00:00

abstract：:The levels of immunoreactive Leu-enkephalin (ir-Leu-Enk) were measured in acid extract of hearts and lungs of adult normotensive Wistar Kyoto (WKY) and spontaneously hypertensive (SHR) rats. Heart contents in ir-Leu-Enk were significantly higher in SHR rats (2.67 pmol/g) than in WKY rats (1.5 pmol/g). However, no sign...

journal_title：Neuroscience letters

authors： Dumont M,Lemaire S

更新日期：1988-11-22 00:00:00

abstract：:Brain derived neurotrophic factor (BDNF), known to promote survival of neurons, has recently been involved in the regulation of endothelial cells and was shown to possess immunoregulatory properties. We therefore asked whether BDNF has immunoregulating effects in human cerebral endothelial cells (HCEC). Adult HCEC exp...

journal_title：Neuroscience letters

authors： Ruprecht K,Stadelmann C,Hummel V,Klein O,Brück W,Rieckmann P

更新日期：2002-09-20 00:00:00

abstract：:Nitric oxide (NO) mediates cell-cell signalling in the brain and stimulates cyclic GMP (cGMP) production in target cells. We have used NADPH-diaphorase (reduced nicotinamide adenine dinucleotide phosphate-diaphorase) histochemistry to identify NO-producing neurones and cGMP immunohistochemistry to locate the targets o...

journal_title：Neuroscience letters

authors： Southam E,Morris R,Garthwaite J

更新日期：1992-03-30 00:00:00

abstract：:Previous studies have shown that the midbrain periaqueductal gray (PAG) projects to the ventrolateral medulla (VLM). Here, we studied PAG projections to the area of A1/C1 neurons in the VLM in the rat using phaseolus vulgaris leucoagglutinin (PHA-L) anterograde tracing combined with immunocytochemistry for tyrosine hy...

journal_title：Neuroscience letters

authors： Chen S,Aston-Jones G

更新日期：1995-08-04 00:00:00

abstract：:Following virus infection of the central nervous system, microglia become activated and undergo morphological as well as functional transformations, thereby initiating effective antiviral actions. Herein, we have examined the contribution of nuclear factor kappaB (NF-kappaB) and mitogen-activated protein kinase (MAPK)...

journal_title：Neuroscience letters

authors： Nakamichi K,Saiki M,Kitani H,Kuboyama Y,Morimoto K,Takayama-Ito M,Kurane I

更新日期：2007-03-13 00:00:00

abstract：:The somatosensory system is capable of functional reorganization following peripheral denervation or training. Studies on human amputees with phantom limb pain provided evidence that these reorganizational changes are modulated through nociceptive input. In the present study we used magnetoencephalographic recordings ...

journal_title：Neuroscience letters

authors： Sörös P,Knecht S,Bantel C,Imai T,Wüsten R,Pantev C,Lütkenhöner B,Bürkle H,Henningsen H

更新日期：2001-02-09 00:00:00

abstract：:The present study has described and quantitated the distribution of mu-opioid receptors in the nucleus raphe magnus (NRM) and nucleus gigantocellularis (NGC), using in vitro autoradiography. Moderately dense binding of a mu-enkephalin analog, DAGO, was observed in the NRM and adjacent parts of the NGC. DAGO binding de...

journal_title：Neuroscience letters

authors： Bowker RM,Dilts RP

更新日期：1988-06-07 00:00:00

abstract：:This investigation was designed to determine the responses of neurons in the posterior group of nuclei (PO) to tooth pulp stimulation. Eighteen tooth pulp-driven (TPD) neurons were recorded in 9 cats anesthetized with nitrous oxide and halothane, 14 of them in the medial part (POM) and the remainder in the lateral par...

journal_title：Neuroscience letters

authors： Matsumoto N,Sato T,Sawano H,Tochinai A,Suzuki TA

更新日期：1988-11-11 00:00:00

abstract：:Adenosine modulates hippocampal synaptic plasticity, namely long-term potentiation (LTP) and long-term depression (LTD), through activation of A1 and A2A receptors. We now report a novel role for the recently described adenosine A3 receptor in the regulation of synaptic plasticity in the CA1 area of hippocampal slices...

journal_title：Neuroscience letters

authors： Costenla AR,Lopes LV,de Mendonça A,Ribeiro JA

更新日期：2001-04-13 00:00:00

abstract：:Micro traumatic brain injury (TBI) is the most common type of brain injury, but the mechanisms underlying it are poorly understood. Aquaporin-4 (AQP4) is a water channel expressed in astrocyte end-feet, which plays an important role in brain edema. However, little is known about the role of AQP4 in micro TBI. Here, we...

journal_title：Neuroscience letters

authors： Liang F,Luo C,Xu G,Su F,He X,Long S,Ren H,Liu Y,Feng Y,Pei Z

更新日期：2015-06-26 00:00:00

abstract：:We describe the incidence of gamma-aminobutyric acid (GABA)ergic neurons after post-embedding immunocytochemistry on semithin sections of the claustrum, putamen and lateral, dorsal and medial cortical areas. Twelve percent of the neurons counted in the claustrum of 11 rabbits were GABAergic. This incidence was signifi...

journal_title：Neuroscience letters

authors： Gómez-Urquijo SM,Gutiérrez-Ibarluzea I,Bueno-López JL,Reblet C

更新日期：2000-03-24 00:00:00

abstract：:Alzheimer's Disease (AD) is a neurodegenerative disorder with a complex aetiology displayed by multiple pathogenic factors. The APOE varepsilon4 allele represents the only established genetic risk factor for sporadic AD; in addition, previous findings on three single nucleotide polymorphisms (SNPs) located on the APOE...

journal_title：Neuroscience letters

authors： Valenza A,Bizzarro A,Marra C,Lauria A,Guglielmi V,Rossi C,Tiziano FD,Brahe C,Masullo C

更新日期：2010-03-26 00:00:00

abstract：:Hippocampal output is mediated via the subiculum, which is the principal target of CA1 pyramidal cells, and which sends projections to a variety of cortical and subcortical regions. Pyramidal cells in the subiculum display two different firing modes and are classified as being burst-spiking or regular-spiking. In a pr...

journal_title：Neuroscience letters

authors： Shor OL,Fidzinski P,Behr J

更新日期：2009-01-16 00:00:00

abstract：:Auditory steady-state responses (ASSRs) are increasingly used in research of neuropsychiatric disorders and for brain-computer interface applications. However, results on attentional modulation of ASSRs are inconclusive. The evaluation of large-scale effects of task-related modulation on ASSRs might give better estima...

journal_title：Neuroscience letters

authors： Griskova-Bulanova I,Pipinis E,Voicikas A,Koenig T

更新日期：2018-05-01 00:00:00

abstract：:After traumatic brain injury (TBI), the primary insult is followed by a cascade of secondary events which lead to enlargement of the primary lesion and are potentially amenable to therapeutic intervention. Lisuride is a dopaminergic agonist with additional serotoninergic, adrenergic, and glutamate antagonistic propert...

journal_title：Neuroscience letters

authors： Zweckberger K,Simunovic F,Kiening KL,Unterberg AW,Sakowitz OW

更新日期：2011-07-25 00:00:00

abstract：:Alterations of Ca2+ homeostasis have been reported for both fibroblasts and T-lymphocytes of patients with Alzheimer's disease (AD). Considering the importance of K+ conductances for the cellular Ca2+ regulation and the recently reported absence of a K+ channel in Alzheimer fibroblasts, we investigated K+ currents in ...

journal_title：Neuroscience letters

authors： Cohen CD,Vollmayr B,Aldenhoff JB

更新日期：1996-01-05 00:00:00

abstract：:Gap junction (GJ) coupling between neocortical GABAergic interneurons plays a critical role in the synchronization of activity in cortical networks in physiological and pathophysiological states, e.g., seizures. Past studies have shown that GJ blockers exert anticonvulsant actions in both in vivo and in vitro models o...

journal_title：Neuroscience letters

authors： Yang L,Ling DS

更新日期：2007-04-18 00:00:00

abstract：:Hydrogen peroxide (H(2)O(2)) is a major reactive oxygen species that has been implicated in various neurodegenerative diseases. Quercetin, one of the plant flavonoids, has been reported to harbor various physiological properties including antioxidant activity. In this study, we investigated the neuroprotective effects...

journal_title：Neuroscience letters

authors： Suematsu N,Hosoda M,Fujimori K

更新日期：2011-10-31 00:00:00