Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism.

abstract：:Diabetes has emerged as a threat to the current world. More than ninety five per cent of all the diabetic population has type 2 diabetes mellitus (T2DM). Aggregates of Amylin hormone, which is co-secreted with insulin from the pancreatic β-cells, inhibit the activities of insulin and glucagon and cause T2DM. Importanc...

journal_title：Scientific reports

authors： Paul A,Kalita S,Kalita S,Sukumar P,Mandal B

更新日期：2017-01-05 00:00:00

abstract：:Combining with electrochemical corrosion measurements, immersion and hydrogen evolution testing performed in 0.9 wt.% NaCl solution at 37 °C, the corrosion resistance of an as-rolled Mg-3%Al-1%Zn alloy before and after a 3% compressive strain along the rolling direction was investigated. Results revealed that the corr...

journal_title：Scientific reports

authors： Wang BJ,Xu DK,Xin YC,Sheng LY,Han EH

更新日期：2017-11-22 00:00:00

abstract：:For the first time, high-surface-area (approximately 1465 m(2) g(-1)), highly porous and heteroatom-enriched activated carbon (HAC) was prepared from banana stems (Musa paradisiaca, Family: Musaceae) at different carbonization temperatures of 700, 800 and 900 °C (HAC) using a simple and eco-friendly method. The amount...

journal_title：Scientific reports

authors： Madhu R,Veeramani V,Chen SM

更新日期：2014-04-23 00:00:00

abstract：:Deep venous thrombosis (DVT) is a common complication of orthopedic surgery. Genetic risk factors and high heritability carried a substantial risk of DVT. In this study, we aimed to investigate the potential association in the Han Chinese population between the polymorphisms of BDKRB2 and KNG1 and DVT after orthopedic...

journal_title：Scientific reports

authors： Wang Q,Cheng G,Wang X,Wang D,Yang Y,Chen K,Ye J,Qing Z

更新日期：2018-11-26 00:00:00

abstract：:Thermal rectifiers whose forward heat fluxes are greater than reverse counterparts have been extensively studied. Here we have discovered, idealized, and derived the ultimate limit of such rectification ratios, which are partially validated by numerical simulations, experiments, and micro-scale Hamiltonian-oscillator ...

journal_title：Scientific reports

authors： Shih TM,Gao Z,Guo Z,Merlitz H,Pagni PJ,Chen Z

更新日期：2015-08-04 00:00:00

abstract：:We propose an error correction procedure based on a cellular automaton, the sweep rule, which is applicable to a broad range of codes beyond topological quantum codes. For simplicity, however, we focus on the three-dimensional toric code on the rhombic dodecahedral lattice with boundaries and prove that the resulting ...

journal_title：Scientific reports

authors： Vasmer M,Browne DE,Kubica A

更新日期：2021-01-21 00:00:00

abstract：:How chromosomes fold into 3D structures and how genome functions are affected or even controlled by their spatial organization remain challenging questions. Hi-C experiment has provided important structural insights for chromosome, and Hi-C data are used here to construct the 3D chromatin structure which are character...

journal_title：Scientific reports

authors： Xie WJ,Meng L,Liu S,Zhang L,Cai X,Gao YQ

更新日期：2017-06-06 00:00:00

abstract：:Technological advances have made it possible to examine dental resin composites using 3D nanometer resolution. This investigation aims to characterize existing dental nano-hybrid and micro-hybrid resin composites through comparing and contrasting nano-computed tomography (nano-CT) with micro-CT and high-resolution SEM...

journal_title：Scientific reports

authors： Haugen HJ,Qasim SB,Matinlinna JP,Vallittu P,Nogueira LP

更新日期：2020-09-23 00:00:00

abstract：:Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap. Here, we evaluated the impact of sexual dimorphism and of the estrous cycle on muscle strength and running power of C57BL/6 mice. Like men, male mi...

journal_title：Scientific reports

authors： Aguiar AS Jr,Speck AE,Amaral IM,Canas PM,Cunha RA

更新日期：2018-07-16 00:00:00

abstract：:Individuals infected with hepatitis C virus (HCV) are at high risk of developing progressive liver disease, including cirrhosis and hepatocellular carcinoma (HCC). How HCV infection causes liver destruction has been of significant interest for many years, and apoptosis has been proposed as one operative mechanism. In ...

journal_title：Scientific reports

authors： Kofahi HM,Taylor NG,Hirasawa K,Grant MD,Russell RS

更新日期：2016-12-15 00:00:00

abstract：:The evaporation of seawater in arid climates is currently the main accepted driving mechanism for the formation of ancient and recent salt deposits in shallow basins. However, the deposition of huge amounts of marine salts, including the formation of tens of metres of highly soluble types (tachyhydrite and bischofite)...

journal_title：Scientific reports

authors： Debure M,Lassin A,Marty NC,Claret F,Virgone A,Calassou S,Gaucher EC

更新日期：2019-08-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Harhay GP,Harhay DM,Bono JL,Capik SF,DeDonder KD,Apley MD,Lubbers BV,White BJ,Larson RL,Smith TPL

更新日期：2020-01-28 00:00:00

abstract：:Multi-modal three dimensional (3D) optical imaging combining both structural sensitivity and molecular specificity is highly desirable in biomedical research. In this paper, we present a method termed oblique scanning laser microscopy (OSLM) to combine optical coherence tomography (OCT), for simultaneously volumetric ...

journal_title：Scientific reports

authors： Zhang L,Capilla A,Song W,Mostoslavsky G,Yi J

更新日期：2017-08-17 00:00:00

abstract：:Previous studies have evaluated gene expression in Alzheimer's disease (AD) brains to identify mechanistic processes, but have been limited by the size of the datasets studied. Here we have implemented a novel meta-analysis approach to identify differentially expressed genes (DEGs) in published datasets comprising 450...

journal_title：Scientific reports

authors： Li X,Long J,He T,Belshaw R,Scott J

更新日期：2015-07-23 00:00:00

abstract：:Anhedonia, the diminished ability to experience pleasure, is a challenging negative symptom in patients with schizophrenia and can be observed in at-risk individuals with schizotypy. Deficits in hedonic processing have been postulated to be related to decreased motivation to engage in potentially rewarding events. It ...

journal_title：Scientific reports

authors： Li X,Li Z,Li K,Zeng YW,Shi HS,Xie WL,Yang ZY,Lui SS,Cheung EF,Leung AW,Chan RC

更新日期：2016-10-18 00:00:00

abstract：:Propionibacterium freudenreichii, a dairy starter, can reach a population of almost 109 propionibacteria per gram in Swiss-type cheese at the time of consumption. Also consumed as a probiotic, it displays strain-dependent anti-inflammatory properties mediated by surface proteins that induce IL-10 in leukocytes. We sel...

journal_title：Scientific reports

authors： Deutsch SM,Mariadassou M,Nicolas P,Parayre S,Le Guellec R,Chuat V,Peton V,Le Maréchal C,Burati J,Loux V,Briard-Bion V,Jardin J,Plé C,Foligné B,Jan G,Falentin H

更新日期：2017-04-13 00:00:00

abstract：:Behavioral addiction (BA) is characterized by repeated, impulsive and compulsive seeking of specific behaviors, even with consequent negative outcomes. In drug addiction, alterations in biological mechanisms, such as monoamines and epigenetic processes, have been suggested, whereas whether such mechanisms are also alt...

journal_title：Scientific reports

authors： Asaoka Y,Won M,Morita T,Ishikawa E,Lee YA,Goto Y

更新日期：2020-07-16 00:00:00

abstract：:Leptin has a central role in the maintenance of energy homeostasis, and its sensitivity is influenced by both the photoperiod and dietary polyphenols. The aim of this study was to investigate the effect of seasonal consumption of polyphenol-rich fruits on the hypothalamic leptin signaling system in non-obese and obese...

journal_title：Scientific reports

authors： Ibars M,Aragonès G,Ardid-Ruiz A,Gibert-Ramos A,Arola-Arnal A,Suárez M,Bladé C

更新日期：2018-09-11 00:00:00

abstract：:To investigate the safety and efficiency of using robotic staplers for intracorporeal gastroduodenostomy in reduced-port robotic gastrectomy for gastric adenocarcinoma. We retrospectively reviewed patients who underwent totally robotic and laparoscopic gastrectomy with intracorporeal gastroduodenostomy. Gastroduodenos...

journal_title：Scientific reports

authors： Kim JS,Batajoo H,Son T,Choi S,Seo WJ,Cho M,Kim YM,Lee JH,Kim HI,Hyung WJ

更新日期：2020-09-07 00:00:00

abstract：:Conventional spin-singlet Cooper pairs convert into spin-triplet pairs in ferromagnetic Josephson junctions in which the superconductor/ferromagnet interfaces (S/F) are magnetically inhomogeneous. Although much of the theoretical work describing this triplet proximity effect has considered ideal junctions with magneti...

journal_title：Scientific reports

authors： Robinson JW,Chiodi F,Egilmez M,Halász GB,Blamire MG

更新日期：2012-01-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Hitrec T,Luppi M,Bastianini S,Squarcio F,Berteotti C,Lo Martire V,Martelli D,Occhinegro A,Tupone D,Zoccoli G,Amici R,Cerri M

更新日期：2020-03-03 00:00:00

abstract：:Stromal capillary sheath cells in human spleens strongly express CD271, the low affinity nerve growth factor receptor p75. Serial sections of a representative adult human spleen were double-stained for CD271 versus smooth muscle alpha actin (SMA) plus CD34 to visualise capillary sheaths, the arterial tree and endothel...

journal_title：Scientific reports

authors： Steiniger BS,Wilhelmi V,Berthold M,Guthe M,Lobachev O

更新日期：2018-10-24 00:00:00

abstract：:HCV NS3 protein plays a central role in viral polyprotein processing and RNA replication. We demonstrate that the NS3 protease (NS3(pro)) domain alone can specifically bind to HCV-IRES RNA, predominantly in the SLIV region. The cleavage activity of the NS3 protease domain is reduced upon HCV-RNA binding. More importan...

journal_title：Scientific reports

authors： Ray U,Das S

更新日期：2011-01-01 00:00:00

abstract：:Electron heating is a fundamental and multidisciplinary phenomenon in partially ionized gases, from the planet's ionosphere to laboratory-scale plasmas. Plasmas produced at ambient or reduced pressures have recently shown potential for scientific and industrial applications. However, electron heating, which is strongl...

journal_title：Scientific reports

authors： Park S,Choe W,Kim H

更新日期：2018-07-05 00:00:00

abstract：:Phagocytosis is a required mechanism for the defense against pathogens. Staphylococcus aureus, an important bacterial pathogen, can promptly escape from phagosomes and proliferate within the cytoplasm of host. However, the mechanism of phagocytosis against S. aureus has not been intensively investigated. In this study...

journal_title：Scientific reports

authors： Zhu F,Zhou Y,Jiang C,Zhang X

更新日期：2015-10-07 00:00:00

abstract：:Experimental evidence supports that signaling pathways can induce different dynamics of transcription factor (TF) activation, but how an input signal is encoded by such a dynamic, noisy TF and further decoded by downstream genes remains largely unclear. Here, using a system of stochastic transcription with signal regu...

journal_title：Scientific reports

authors： Liu P,Wang H,Huang L,Zhou T

更新日期：2017-02-08 00:00:00

abstract：:The submarine volcano Axial Seamount has exhibited an inflation predictable eruption cycle, which allowed for the successful forecast of its 2015 eruption. However, the exact triggering mechanism of its eruptions remains ambiguous. The inflation predictable eruption pattern suggests a magma reservoir pressure threshol...

journal_title：Scientific reports

authors： Cabaniss HE,Gregg PM,Nooner SL,Chadwick WW Jr

更新日期：2020-06-23 00:00:00

abstract：:Influenza's propensity for antigenic drift and shift, and to elicit predominantly strain specific antibodies (Abs) leaves humanity susceptible to waves of new strains with pandemic potential for which limited or no immunity may exist. Subsequently new clinical interventions are needed. To identify hemagglutinin (HA) e...

journal_title：Scientific reports

authors： Nogales A,Piepenbrink MS,Wang J,Ortega S,Basu M,Fucile CF,Treanor JJ,Rosenberg AF,Zand MS,Keefer MC,Martinez-Sobrido L,Kobie JJ

更新日期：2018-03-12 00:00:00

abstract：:High frequency oscillations (HFOs) are bursts of neural activity in the range of 80 Hz or higher, recorded from intracranial electrodes during epileptiform discharges. HFOs are a proposed biomarker of epileptic brain tissue and may also be useful for seizure forecasting. Despite such clinical utility of HFOs, the spat...

journal_title：Scientific reports

authors： Smith EH,Merricks EM,Liou JY,Casadei C,Melloni L,Thesen T,Friedman DJ,Doyle WK,Emerson RG,Goodman RR,McKhann GM 2nd,Sheth SA,Rolston JD,Schevon CA

更新日期：2020-11-05 00:00:00

abstract：:In this paper, we demonstrate a novel dual-pump approach to generate robust optical frequency comb with varying free spectral range (FSR) spacing in a CMOS-compatible high-Q micro-ring resonator (MRR). The frequency spacing of the comb can be tuned by an integer number FSR of the MRR freely in our dual-pump scheme. Th...

journal_title：Scientific reports

authors： Wang W,Chu ST,Little BE,Pasquazi A,Wang Y,Wang L,Zhang W,Wang L,Hu X,Wang G,Hu H,Su Y,Li F,Liu Y,Zhao W

更新日期：2016-06-24 00:00:00