Structural Modeling of Chromatin Integrates Genome Features and Reveals Chromosome Folding Principle.

abstract：:Snake venom is a natural substance that contains numerous bioactive proteins and peptides, nearly all of which have been identified over the last several decades. In this study, we subjected snake venom to enzymatic hydrolysis to identify previously unreported bioactive peptides. The novel peptide ACH-11 with the sequ...

journal_title：Scientific reports

authors： Chen M,Ye X,Ming X,Chen Y,Wang Y,Su X,Su W,Kong Y

更新日期：2015-06-02 00:00:00

abstract：:The intermittent electromagnetic fields with a large [Formula: see text] can enhance the properties of ferromagnetic materials and significantly affect paramagnetic materials. In this study, the effect of a pulsed electromagnetic field on the crystal orientation of the primary phase and microstructure evolution of an ...

journal_title：Scientific reports

authors： Bai Q,Wang J,Xing S,Ma Y,Bao X

更新日期：2020-06-30 00:00:00

abstract：:We demonstrate a method for the preparation of negative-index fibre Bragg gratings (FBGs) using 800 nm femtosecond laser overexposure and thermal regeneration. A positive-index type I-IR FBG was first inscribed in H2-free single-mode fibre using a femtosecond laser directed through a phase mask, and then a highly pola...

journal_title：Scientific reports

authors： He J,Wang Y,Liao C,Wang C,Liu S,Yang K,Wang Y,Yuan X,Wang GP,Zhang W

更新日期：2016-03-16 00:00:00

abstract：:Mixed fisheries are the dominant type of fishery worldwide. Overexploitation in mixed fisheries occurs when catches continue for available quota species while low quota species are discarded. As EU fisheries management moves to count all fish caught against quota (the "landing obligation"), the challenge is to catch a...

journal_title：Scientific reports

authors： Dolder PJ,Thorson JT,Minto C

更新日期：2018-09-17 00:00:00

abstract：:Axolotls have the amazing ability to regenerate. When compared to humans, axolotls display a very fast wound closure, no scarring and are capable to replace lost appendages perfectly. Understanding the signaling mechanism leading to this perfect healing is a key step to help develop regenerative treatments for humans....

journal_title：Scientific reports

authors： Sader F,Denis JF,Laref H,Roy S

更新日期：2019-02-04 00:00:00

abstract：:Increasingly researchers are looking to bring together perspectives across multiple scales, or to combine insights from different techniques, for the same region of interest. To this end, correlative microscopy has already yielded substantial new insights in two dimensions (2D). Here we develop correlative tomography ...

journal_title：Scientific reports

authors： Burnett TL,McDonald SA,Gholinia A,Geurts R,Janus M,Slater T,Haigh SJ,Ornek C,Almuaili F,Engelberg DL,Thompson GE,Withers PJ

更新日期：2014-04-16 00:00:00

abstract：:Fabrication of uniform vertically-aligned titanium dioxide nanorods (TiO2 NRs) was achieved by hydrothermal growth on a fluorine-doped tin oxide (FTO) glass substrate. The substrate was coated by a TiO2 seed layer composed of titanium (IV) butoxide (TBO) as a precursor in an HCl solution. To reduce the amount of toxic...

journal_title：Scientific reports

authors： Prathan A,Sanglao J,Wang T,Bhoomanee C,Ruankham P,Gardchareon A,Wongratanaphisan D

更新日期：2020-05-15 00:00:00

abstract：:We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hydrodynamic pattern ...

journal_title：Scientific reports

authors： Ashwinbalaji S,Senthilkumari S,Gowripriya C,Krishnadas S,Gabelt BAT,Kaufman PL,Muthukkaruppan V

更新日期：2018-10-19 00:00:00

abstract：:The rockpool shrimp Palaemon elegans is an ecologically important crustacean species within the European coastline fauna. In the present study, genetic diversity and population structure and connectivity were assessed by examining 21 polymorphic microsatellite loci at 13 sampling sites located along the natural distri...

journal_title：Scientific reports

authors： González-Castellano I,González-López J,González-Tizón AM,Martínez-Lage A

更新日期：2020-07-01 00:00:00

abstract：:The endogenous circadian clock drives oscillations that are completely synchronized with the environmental day-night rhythms with a period of approximately 24 hours. Temporal misalignment between one's internal circadian clock and the external solar time often occurs in shift workers and long-distance travelers; such ...

journal_title：Scientific reports

authors： Kori H,Yamaguchi Y,Okamura H

更新日期：2017-04-26 00:00:00

abstract：:Hydrogen sulfide (H2S) signaling has been considered a key regulator of plant developmental processes and defenses. In this study, we demonstrate that high levels of H2S inhibit auxin transport and lead to alterations in root system development. H2S inhibits auxin transport by altering the polar subcellular distributi...

journal_title：Scientific reports

authors： Jia H,Hu Y,Fan T,Li J

更新日期：2015-02-05 00:00:00

abstract：:Optimized mesoporous photocatalyst endowed with high specific surface area and large pore size was synthesized by sol-gel method. These large pore mesoporous materials (33.39 nm) were conducive to the movement of larger molecules or groups in pore path and for effective use of active sites. The high specific surface a...

journal_title：Scientific reports

authors： Xue H,Jiang Y,Yuan K,Yang T,Hou J,Cao C,Feng K,Wang X

更新日期：2016-07-19 00:00:00

abstract：:Endocannabinoids are small signaling lipids, with 2-arachidonoylglycerol (2-AG) implicated in modulating axonal growth and synaptic plasticity. The concept of short-range extracellular signaling by endocannabinoids is supported by the lack of trans-synaptic 2-AG signaling in mice lacking sn-1-diacylglycerol lipases (D...

journal_title：Scientific reports

authors： Keimpema E,Alpár A,Howell F,Malenczyk K,Hobbs C,Hurd YL,Watanabe M,Sakimura K,Kano M,Doherty P,Harkany T

更新日期：2013-01-01 00:00:00

abstract：:Here, we report direct band gap transition for Gallium Phosphide (GaP) when alloyed with just 1-2 at% antimony (Sb) utilizing both density functional theory based computations and experiments. First principles density functional theory calculations of GaSbxP(1-x) alloys in a 216 atom supercell configuration indicate t...

journal_title：Scientific reports

authors： Russell HB,Andriotis AN,Menon M,Jasinski JB,Martinez-Garcia A,Sunkara MK

更新日期：2016-02-10 00:00:00

abstract：:Plant defensins (PDFs) are cysteine-rich peptides that have a range of biological functions, including defence against fungal pathogens. However, little is known about their role in defence against bacteria. In this study, we showed that the protein encoded by ARABIDOPSIS THALIANA PLANT DEFENSIN TYPE 1.1 (AtPDF1.1) is...

journal_title：Scientific reports

authors： Hsiao PY,Cheng CP,Koh KW,Chan MT

更新日期：2017-08-23 00:00:00

abstract：:Scrapie is a lethal neurodegenerative disease of sheep and goats caused by the misfolding of the prion protein. Variants such as M142, D145, S146, H154, Q211, and K222 were experimentally found to increase resistance or extend scrapie incubation period in goats. We aimed to identify polymorphisms in the Afar and Arsi-...

journal_title：Scientific reports

authors： Teferedegn EY,Yaman Y,Ün C

更新日期：2020-04-24 00:00:00

abstract：:The formation and motion features of self interstitial atom (SIA) clusters in tungsten are studied by molecular dynamics (MD) simulations. The static calculations show that the SIA clusters are stable with binding energy over 2 eV. The SIA clusters exhibit a fast one dimensional (1D) motion along 〈111〉. Through analys...

journal_title：Scientific reports

authors： Zhou WH,Zhang CG,Li YG,Zeng Z

更新日期：2014-05-28 00:00:00

abstract：:Breast cancer is the most frequently diagnosed malignancy among women, and triple-negative breast cancer (TNBC) is a highly aggressive subtype. Increasing evidence has shown that lncRNAs are involved in tumor growth, cell-cycle, and apoptosis through interactions with miRNAs or mRNAs. However, there is still limited d...

journal_title：Scientific reports

authors： Le K,Guo H,Zhang Q,Huang X,Xu M,Huang Z,Yi P

更新日期：2019-10-22 00:00:00

abstract：:Concurrent generation and mixing phenomenon of thermoacoustic (TA) and magnetoacoustic (MA) waves in water are predicted and observed. A theory unifying TA and MA is further put forward to analyze it. By scaling down the radio frequency in thermoacoustics to the low mega Hertz range and by incorporating appropriately ...

journal_title：Scientific reports

authors： Feng X,Gao F,Kishor R,Zheng Y

更新日期：2015-06-26 00:00:00

abstract：:Are cooperative decisions typically made more quickly or slowly than non-cooperative decisions? While this question has attracted considerable attention in recent years, most research has focused on one-shot interactions. Yet it is repeated interactions that characterize most important real-world social interactions. ...

journal_title：Scientific reports

authors： Nishi A,Christakis NA,Evans AM,O'Malley AJ,Rand DG

更新日期：2016-07-20 00:00:00

abstract：:Surgery and anesthesia induce inflammatory changes in the central nervous system, which ultimately lead to neuronal damage concomitant with an increase in the level of neurodegeneration markers. Despite some experimental data showing prolonged activation of the immune system post-surgery, no study has determined the e...

journal_title：Scientific reports

authors： DiMeglio M,Furey W,Hajj J,Lindekens J,Patel S,Acker M,Bavaria J,Szeto WY,Atluri P,Haber M,Diaz-Arrastia R,Laudanski K

更新日期：2019-05-09 00:00:00

abstract：:In the field of neuroprosthetics, the current state-of-the-art method involves controlling the prosthesis with electromyography (EMG) or electrooculography/electroencephalography (EOG/EEG). However, these systems are both expensive and time consuming to calibrate, susceptible to interference, and require a lengthy lea...

journal_title：Scientific reports

authors： Hazubski S,Hoppe H,Otte A

更新日期：2020-10-01 00:00:00

abstract：:Most bacterial cytochrome P450 monooxygenases (P450s or CYPs) require two redox partner proteins for activity. To reduce complexity of the redox chain, the Bacillus subtilis flavodoxin YkuN (Y) was fused to the Escherichia coli flavodoxin reductase Fpr (R), and activity was tuned by placing flexible (GGGGS)n or rigid ...

journal_title：Scientific reports

authors： Bakkes PJ,Riehm JL,Sagadin T,Rühlmann A,Schubert P,Biemann S,Girhard M,Hutter MC,Bernhardt R,Urlacher VB

更新日期：2017-08-29 00:00:00

abstract：:In this study, 111 Cryptosporidium parvum IId isolates from several species of animals in China, Sweden, and Egypt were subtyped by multilocus sequence typing (MLST). One to eleven subtypes were detected at each of the 12 microsatellite, minisatellite, and single nucleotide polymorphism (SNP) loci, forming 25 MLST sub...

journal_title：Scientific reports

authors： Wang R,Zhang L,Axén C,Bjorkman C,Jian F,Amer S,Liu A,Feng Y,Li G,Lv C,Zhao Z,Qi M,Dong H,Wang H,Sun Y,Ning C,Xiao L

更新日期：2014-02-27 00:00:00

abstract：:Cross-linked protein crystals (CLPCs) are very useful materials in applications such as biosensors, catalysis, and X-ray crystallography. Hence, preparation of CLPCs is an important research direction. During the preparation of CLPCs, an often encountered problem is that cracks may appear in the crystals, which may fi...

journal_title：Scientific reports

authors： Yan EK,Lu QQ,Zhang CY,Liu YL,He J,Chen D,Wang B,Zhou RB,Wu P,Yin DC

更新日期：2016-10-05 00:00:00

abstract：:Unambiguous identification of trace amounts of biochemical molecules in a complex background using terahertz spectroscopy is extremely challenging owing to the extremely small absorption cross sections of these molecules in the terahertz regime. Herein, we numerically propose a terahertz nonresonant nano-slits structu...

journal_title：Scientific reports

authors： Qin J,Cheng W,Han B,Du Y,Han Z,Zhao Z

更新日期：2020-02-28 00:00:00

abstract：:Third-generation sequencing technologies allow to sequence long reads of tens of kbp, that are expected to solve various problems. However, they display high error rates, currently capped around 10%. Self-correction is thus regularly used in long reads analysis projects. We introduce CONSENT, a new self-correction met...

journal_title：Scientific reports

authors： Morisse P,Marchet C,Limasset A,Lecroq T,Lefebvre A

更新日期：2021-01-12 00:00:00

abstract：:Boiling histotripsy (BH) is a High Intensity Focused Ultrasound (HIFU) method for precise mechanical disintegration of target tissue using millisecond-long pulses containing shocks. BH treatments with real-time ultrasound (US) guidance allowed by BH-generated bubbles were previously demonstrated ex vivo and in vivo in...

journal_title：Scientific reports

authors： Khokhlova TD,Schade GR,Wang YN,Buravkov SV,Chernikov VP,Simon JC,Starr F,Maxwell AD,Bailey MR,Kreider W,Khokhlova VA

更新日期：2019-12-27 00:00:00

abstract：:In the chemical mechanical polishing process of semiconductor manufacturing, the concentration of 'large' particles ([Formula: see text]0.5 μm) in the slurry, which is considerably larger in size than the main abrasives ([Formula: see text] 0.1 μm), is a critical parameter that strongly influences manufacturing defect...

journal_title：Scientific reports

authors： Lee M,Kim D,Heo TY,Park T,Kim W,Choi D,Kim H,Kim J

更新日期：2020-09-07 00:00:00

abstract：:Precision Medicine in Oncology requires tailoring of therapeutic strategies to individual cancer patients. Due to the limited quantity of tumor samples, this proves to be difficult, especially for early stage cancer patients whose tumors are small. In this study, we exploited a 2.4 × 2.4 centimeters polydimethylsiloxa...

journal_title：Scientific reports

authors： Wong AH,Li H,Jia Y,Mak PI,Martins RPDS,Liu Y,Vong CM,Wong HC,Wong PK,Wang H,Sun H,Deng CX

更新日期：2017-08-22 00:00:00