Spatial separation of catches in highly mixed fisheries.

abstract：:Alcoholic liver disease (ALD) causes significant morbidity and mortality, and pharmacological treatment options are limited. In this study, we evaluated the PCSK9 inhibitor alirocumab, a monoclonal antibody that robustly reduces low-density lipoprotein cholesterol (LDL-C), for the treatment of ALD using a rat model of...

journal_title：Scientific reports

authors： Lee JS,Mukhopadhyay P,Matyas C,Trojnar E,Paloczi J,Yang YR,Blank BA,Savage C,Sorokin AV,Mehta NN,Vendruscolo JCM,Koob GF,Vendruscolo LF,Pacher P,Lohoff FW

更新日期：2019-11-20 00:00:00

abstract：:Current studies addressing the influence of interleukin-33 or its receptor (IL-33R/ST2) on development of atopic dermatitis-like inflammation in mice have reported conflicting results. We compared the response in single- and double-deficient IL-33-/-/ST2-/- C57BL/6J BomTac mice in the well-established calcipotriol-ind...

journal_title：Scientific reports

authors： Pietka W,Sundnes O,Hammarström C,Zucknick M,Khnykin D,Haraldsen G

更新日期：2020-04-15 00:00:00

abstract：:Bacterial pneumonia is a major cause of acute lung injury and acute respiratory distress syndrome, characterized by alveolar barrier disruption. NLRP3 is best known for its ability to form inflammasomes and to regulate IL-1β and IL-18 production in myeloid cells. Here we show that NLRP3 protects the integrity of the a...

journal_title：Scientific reports

authors： Kostadinova E,Chaput C,Gutbier B,Lippmann J,Sander LE,Mitchell TJ,Suttorp N,Witzenrath M,Opitz B

更新日期：2016-08-01 00:00:00

abstract：:Three major white matter pathways connect the posterior temporal region and the adjacent inferior parietal lobule with the lateral frontal cortex: the arcuate fasciculus (AF), and the second and third branches of the superior longitudinal fasciculus (SLF II and SLF III). These pathways are found also in nonhuman prima...

journal_title：Scientific reports

authors： Barbeau EB,Descoteaux M,Petrides M

更新日期：2020-05-18 00:00:00

abstract：:Sodium butyrate (NaBu), a form of short-chain fatty acid (SCFA), acts classically as a potent anti-angiogenic agent in tumour angiogenesis models, some authors demonstrated that low concentrations of NaBu may contribute to healing of tendon-bone injury in part at least through promotion of tissue remodelling. Here, we...

journal_title：Scientific reports

authors： Liu D,Andrade SP,Castro PR,Treacy J,Ashworth J,Slevin M

更新日期：2016-10-03 00:00:00

abstract：:Skin ageing is an inevitable consequence of life and accelerated by exposure to ultraviolet (UV) rays. Senescence is an irreversible growth arrest and senescent cells accumulate in ageing tissues, at sites of age-related pathologies and in pre-neoplastic lesions. Conventionally, senescent cells have been detected by s...

journal_title：Scientific reports

authors： Wang AS,Ong PF,Chojnowski A,Clavel C,Dreesen O

更新日期：2017-11-15 00:00:00

abstract：:The interplay between the quasi 1-dimensional CuO-chains and the 2-dimensional CuO2 planes of YBa(2)Cu(3)O(6+x) (YBCO) has been in focus for a long time. Although the CuO-chains are known to be important as charge reservoirs that enable superconductivity for a range of oxygen doping levels in YBCO, the understanding o...

journal_title：Scientific reports

authors： Magnuson M,Schmitt T,Strocov VN,Schlappa J,Kalabukhov AS,Duda LC

更新日期：2014-11-12 00:00:00

abstract：:Blockage of Delta-like 4 (DLL4)-directed Notch signaling induces excessive tip cell formation and endothelial proliferation resulting in dysfunctional angiogenesis in tumors. MMGZ01, as a murine anti-human DLL4 monoclonal antibody, specifically binds to human DLL4 and blocks Notch pathway. Here, the structure of MMGZ0...

journal_title：Scientific reports

authors： Jia X,Wang W,Xu Z,Wang S,Wang T,Wang M,Wu M

更新日期：2016-06-15 00:00:00

abstract：:Meteorite impacts have caused catastrophic perturbations to the global environment and mass extinctions throughout the Earth's history. Here, we present petrographic and geochemical evidence of a possible impact ejecta layer, dating from about 11 Ma, in deep-sea clayey sediment in the Northwest Pacific. This clay laye...

journal_title：Scientific reports

authors： Nozaki T,Ohta J,Noguchi T,Sato H,Ishikawa A,Takaya Y,Kimura JI,Chang Q,Shimada K,Ishibashi JI,Yasukawa K,Kimoto K,Iijima K,Kato Y

更新日期：2019-11-20 00:00:00

abstract：:The interpenetrating morphology formed by the electron donor and acceptor materials is critical for the performance of polymer:fullerene bulk heterojunction (BHJ) photovoltaic (PV) cells. In this work we carried out a systematic investigation on a high PV efficiency (>6%) BHJ system consisting of a newly developed 5,6...

journal_title：Scientific reports

authors： Xiao T,Xu H,Grancini G,Mai J,Petrozza A,Jeng US,Wang Y,Xin X,Lu Y,Choon NS,Xiao H,Ong BS,Lu X,Zhao N

更新日期：2014-06-09 00:00:00

abstract：:Polysialic acid (PSA) is a large negatively charged glycan mainly attached to the neural cell adhesion molecule (NCAM). Several studies have shown that it is important for correct formation of brain circuitries during development and for synaptic plasticity, learning and memory in the adult. PSA also plays a major rol...

journal_title：Scientific reports

authors： Saini V,Lutz D,Kataria H,Kaur G,Schachner M,Loers G

更新日期：2016-06-21 00:00:00

abstract：:Diverse communities can adjust their trait composition to altered environmental conditions, which may strongly influence their dynamics. Previous studies of trait-based models mainly considered only one or two trophic levels, whereas most natural system are at least tritrophic. Therefore, we investigated how the addit...

journal_title：Scientific reports

authors： Ceulemans R,Gaedke U,Klauschies T,Guill C

更新日期：2019-05-17 00:00:00

abstract：:Dopamine is an important neurotransmitter that plays a key role in a wide range of both locomotive and cognitive functions in humans. Disturbances on the dopaminergic system cause, among others, psychosis, Parkinson's disease and Huntington's disease. Antipsychotics are drugs that interact primarily with the dopamine ...

journal_title：Scientific reports

authors： Goode-Romero G,Winnberg U,Domínguez L,Ibarra IA,Vargas R,Winnberg E,Martínez A

更新日期：2020-12-09 00:00:00

abstract：:Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy. In this study, we report the development of a novel DNAzyme that can efficiently cle...

journal_title：Scientific reports

authors： Chakravarthy M,Aung-Htut MT,Le BT,Veedu RN

更新日期：2017-05-09 00:00:00

abstract：:We aimed to investigate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in evaluating blunt abdominal trauma for patients presenting to the emergency department. Electronic search of Scopus and Pubmed was performed from inception to September 2016. Human studies investigating the diagnostic accuracy of ...

journal_title：Scientific reports

authors： Zhang Z,Hong Y,Liu N,Chen Y

更新日期：2017-06-30 00:00:00

abstract：:Leukotriene E4 (LTE4) the most stable of the cysteinyl leukotrienes (cysLTs) binds poorly to classical type 1 (CysLT1) and 2 (CysLT2) receptors although it induces potent responses in human airways in vivo, such as bronchoconstriction, airway hyperresponsiveness and inflammatory cell influx suggesting the presence of ...

journal_title：Scientific reports

authors： Foster HR,Fuerst E,Branchett W,Lee TH,Cousins DJ,Woszczek G

更新日期：2016-02-02 00:00:00

abstract：:Afforestation is an important approach to mitigate global warming. Its complex interactions with the climate system, however, makes it controversial. Afforestation is expected to be effective in the tropics where biogeochemical and biogeophysical effects act in concert; however, its potential in the large semi-arid re...

journal_title：Scientific reports

authors： Yosef G,Walko R,Avisar R,Tatarinov F,Rotenberg E,Yakir D

更新日期：2018-01-17 00:00:00

abstract：:Early cow-calf separation prevents much of cows' natural maternal behaviour. Early separation is thought to prevent the development of a cow-calf bond. To assess this bond, we measured motivation of dairy cows to reunite with their calf. To vary the degree of bonding, some cows were allowed continued contact with thei...

journal_title：Scientific reports

authors： Wenker ML,Bokkers EAM,Lecorps B,von Keyserlingk MAG,van Reenen CG,Verwer CM,Weary DM

更新日期：2020-08-28 00:00:00

abstract：:Many reports have demonstrated that radiation stimulates reactive oxygen species (ROS) production by mitochondria for a few hours to a few days after irradiation. However, these studies were performed using cell lines, and there is a lack of information about redox homeostasis in irradiated animals and humans. Blood r...

journal_title：Scientific reports

authors： Sun L,Inaba Y,Sato K,Hirayama A,Tsuboi K,Okazaki R,Chida K,Moritake T

更新日期：2018-05-09 00:00:00

abstract：:We present a combined geomorphological and biochronological study aimed at providing age constraints to the deposits forming a wide paleo-surface in the coastal area of the Tyrrhenian Sea, south of Anzio promontory (central Italy). We review the faunal assemblage recovered in Campoverde, evidencing the occurrence of t...

journal_title：Scientific reports

authors： Marra F,Petronio C,Ceruleo P,Di Stefano G,Florindo F,Gatta M,La Rosa M,Rolfo MF,Salari L

更新日期：2018-12-13 00:00:00

abstract：:We propose a new approach to the generation of acoustic frequency combs (AFC)-signals with spectra containing equidistant coherent peaks. AFCs are essential for a number of sensing and measurement applications, where the established technology of optical frequency combs suffers from fundamental physical limitations. O...

journal_title：Scientific reports

authors： Nguyen BQH,Maksymov IS,Suslov SA

更新日期：2021-01-08 00:00:00

abstract：:Symbiodinium is best-known as the photosynthetic symbiont of corals, but some clades are symbiotic in other organisms or include free-living forms. Identifying similarities and differences among these clades can help us understand their relationship with corals, and thereby inform on measures to manage coral reefs in ...

journal_title：Scientific reports

authors： González-Pech RA,Ragan MA,Chan CX

更新日期：2017-11-03 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Wolpe N,Zhang J,Nombela C,Ingram JN,Wolpert DM,Cam-CAN.,Rowe JB

更新日期：2018-11-22 00:00:00

abstract：:High-quality GaN epitaxial films have been grown on Si substrates with Al buffer layer by the combination of molecular beam epitaxy (MBE) and pulsed laser deposition (PLD) technologies. MBE is used to grow Al buffer layer at first, and then PLD is deployed to grow GaN epitaxial films on the Al buffer layer. The surfac...

journal_title：Scientific reports

authors： Wang W,Wang H,Yang W,Zhu Y,Li G

更新日期：2016-04-22 00:00:00

abstract：:Myostatin (Mstn) is a conserved negative regulator of skeletal muscle mass in mammals. However, whether precise disruption of Mstn in livestock can be achieved and safely used to improve meat productivity has not been proven. We applied CRISPR/Cas9 system to generate Mstn knock-out (KO) rabbits and goats and then anal...

journal_title：Scientific reports

authors： Guo R,Wan Y,Xu D,Cui L,Deng M,Zhang G,Jia R,Zhou W,Wang Z,Deng K,Huang M,Wang F,Zhang Y

更新日期：2016-07-15 00:00:00

abstract：:Crypt neurons are a third type of olfactory receptor neurons with a highly unusual "one cell type--one receptor" mode of expression, the same receptor being expressed by the entire population of crypt neurons. Attempts to identify the target region(s) of crypt neurons have been inconclusive so far. We report that TrkA...

journal_title：Scientific reports

authors： Ahuja G,Ivandic I,Saltürk M,Oka Y,Nadler W,Korsching SI

更新日期：2013-01-01 00:00:00

abstract：:The family of materials defined as ZrSiX (X = S, Se, Te) has been established as Dirac node-line semimetals, and subsequent study is urgent to exploit the promising applications of unusual magnetoresistance (MR) properties. Herein, we systematically investigated the anisotropic MR in the newly-discovered Dirac node-li...

journal_title：Scientific reports

authors： Pan H,Tong B,Yu J,Wang J,Fu D,Zhang S,Wu B,Wan X,Zhang C,Wang X,Song F

更新日期：2018-06-19 00:00:00

abstract：:Coral reefs around the world are undergoing severe decline in the past few decades. Mass coral mortalities have predominantly been reported to be caused by coral bleaching or disease outbreaks. Temporary hypoxic conditions caused by algal blooms can trigger mass coral mortalities though are reported rarely. In this st...

journal_title：Scientific reports

authors： Raj KD,Mathews G,Obura DO,Laju RL,Bharath MS,Kumar PD,Arasamuthu A,Kumar TKA,Edward JKP

更新日期：2020-12-17 00:00:00

abstract：:Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulated in various human carcinoma...

journal_title：Scientific reports

authors： Mishel S,Shneyer B,Korsensky L,Goldshmidt-Tran O,Haber T,Machluf M,Ron D

更新日期：2017-11-08 00:00:00

abstract：:Over the years, electrophysiological recordings in macaque monkeys performing visuomotor tasks brought about accumulating evidence for the expression of neuronal properties (e.g., selectivity in the visuospatial and somatosensory domains, encoding of visual affordances and motor cues) in the posterior parietal area V6...

journal_title：Scientific reports

authors： Santandrea E,Breveglieri R,Bosco A,Galletti C,Fattori P

更新日期：2018-05-02 00:00:00