Abstract:
:Translational control is a common mechanism used to regulate gene expression and occur in bacteria to mammals. Typically in translational control, an RNA-binding protein binds to a unique sequence in the mRNA to regulate protein synthesis by the ribosomes. Alternatively, a protein may bind to or modify a translation factor to globally regulate protein synthesis by the cell. Here, we review translational control by the fragile X mental retardation protein (FMRP), the absence of which causes the neurological disease, fragile X syndrome (FXS).
journal_name
Biochimiejournal_title
Biochimieauthors
Chen E,Joseph Sdoi
10.1016/j.biochi.2015.02.005subject
Has Abstractpub_date
2015-07-01 00:00:00pages
147-54eissn
0300-9084issn
1638-6183pii
S0300-9084(15)00040-1journal_volume
114pub_type
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