A review of contact dermatitis associated with transdermal therapeutic systems.

Abstract:

:The literature is reviewed for contact dermatitis associated with transdermal therapeutic systems. Clonidine, nitroglycerin, scopolamine, estradiol and testosterone are utilized in such applications, and fentanyl is under investigation. Most cutaneous reactions are limited to localized dermatitis; however, generalized systemic effects may occur. Investigators are reporting skin-related side-effects in up to 50% of patients using transdermal clonidine; however, with the other agents, this is demonstrated much less frequently. Reactivation of the dermatitis via oral medication, following sensitization to the patch, is noted in rare instances.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Holdiness MR

doi

10.1111/j.1600-0536.1989.tb03087.x

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

3-9

issue

1

eissn

0105-1873

issn

1600-0536

journal_volume

20

pub_type

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