Percutaneous absorption of 3 organic solvents in the guinea pig (V). Effect of "accelerants".

Abstract:

:The influence of "accelerants" on the percutaneous absorption of 3 organic solvents (butanol, toluene, 1,1,1-trichloroethane) was investigated in the guinea pig. DMSO in binary and ternary mixtures with various concentrations, the result of adding 0.1 M C18 fatty acids, and of pretreatment with DMSO and olive oil, were studied. Addition of DMSO (binary solutions) resulted in increased or decreased absorption of the solvents related to their water solubility. There was reduced absorption of toluene and trichloroethane in binary mixtures with DMSO, while DMSO in binary mixture with butanol gave a marked increase, with concentrations of 50 and 75%. Pretreatment with DMSO resulted in a decrease in the absorption of toluene and a marked increase in the absorption of butanol. The same tendency was seen when skin was pretreated with olive oil under occlusion. The results indicate that the effect of DMSO is related to the water solubility of the penetrant.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Boman A

doi

10.1111/j.1600-0536.1989.tb04748.x

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

304-11

issue

5

eissn

0105-1873

issn

1600-0536

journal_volume

21

pub_type

杂志文章
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    doi:10.1111/j.1600-0536.1995.tb00780.x

    authors: Färm G,Karlberg AT,Lidén C

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    doi:10.1111/j.1600-0536.1997.tb00393.x

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    更新日期:1997-03-01 00:00:00

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    doi:10.1111/j.1600-0536.1993.tb03555.x

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  • Immediate and delayed contact hypersensitivity to verbena plants.

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    pub_type: 杂志文章

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  • The nickel dose-response relationship by filaggrin genotype (FLG).

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    pub_type: 杂志文章

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  • Contact allergy to kojic acid in skin care products.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1995.tb00832.x

    authors: Nakagawa M,Kawai K,Kawai K

    更新日期:1995-01-01 00:00:00

  • Nickel deposited on the skin-visualization by DMG test.

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    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2010.01856.x

    authors: Julander A,Skare L,Vahter M,Lidén C

    更新日期:2011-03-01 00:00:00

  • An overview of the efficacy of topical corticosteroids in experimental human nickel contact dermatitis.

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    pub_type: 杂志文章,评审

    doi:10.1034/j.1600-0536.2000.043006317.x

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    更新日期:2000-12-01 00:00:00

  • Sunflower allergy. On the constituents of the trichomes of Helianthus annuus L. (Compositae).

    abstract::Sesquiterpene lactones (STL) of the sunflower, occurring in fragile multicellular capitate glandular hairs, have been shown to display a remarkable sensitizing capacity when investigated by experimental sensitization in guinea pigs. The strongest response was induced by the hemiketal form of 1-O-methyl-4,5-dihydronive...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb03168.x

    authors: Hausen BM,Spring O

    更新日期:1989-05-01 00:00:00

  • Evaluation of the sensitising potential of 4 polyamines present in technical triethylenetetramine using 2 animal species.

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    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1988.tb04498.x

    authors: Maisey J,Purchase R,Robbins MC,Miller K

    更新日期:1988-03-01 00:00:00

  • Structure-activity relationships in allergic contact dermatitis induced by methacrylates. Studies of the influence of side-chain length of methacrylates.

    abstract::Some methacrylates are known to be strong contact sensitizers. To determine the effect of side-chain length on sensitizing potential, we examined 11 derivatives with linear side chains from C1 to C18 in an experimental sensitization test in guinea pigs. The results showed an increase in the sensitizing potential with ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1999.tb05971.x

    authors: Kanazawa Y,Yoshida T,Kojima K

    更新日期:1999-01-01 00:00:00

  • Temperature-dependent nickel release from nickel alloys.

    abstract::Nickel release from Danish one krone coins and metal buttons from jeans has been measured at 20 degrees C in distilled water and at 35 degrees C in distilled water and synthetic sweat. The temperature elevation increased the nickel release from the coins and two of the nine metal buttons investigated. Obviously the se...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04803.x

    authors: Menne T,Solgaard P

    更新日期:1979-03-01 00:00:00

  • 2-methoxy-6-pentyl-1,4-dihydroxybenzene (miconidin) from Primula obconica: a possible allergen?

    abstract::Miconidin (2-methoxy-6-pentyl-1,4-dihydroxybenzene) and the allergen primin (2-methoxy-6-pentyl-1,4-benzoquinone) have been isolated from fresh unchopped plant material (leaves, stems and flowers together) of Primula obconica. Miconidin and primin were obtained in approximately equal amounts and their structures deter...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1995.tb00507.x

    authors: Krebs M,Christensen LP

    更新日期:1995-08-01 00:00:00

  • Age distribution of the incidence of contact sensitivity to standard allergens.

    abstract::The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04910.x

    authors: Sugai T,Takagi T,Yamamoto S,Takahashi Y

    更新日期:1979-12-01 00:00:00

  • Occupational contact dermatitis caused by 1,3-benzenedimethanamine, N-(2-phenylethyl) derivatives in hardeners for epoxy paints and coatings.

    abstract:BACKGROUND:Amines in epoxy hardeners are significant causes of occupational allergic contact dermatitis among workers who use epoxy resin systems. OBJECTIVES:To describe a novel group of contact allergens: N-(2-phenylethyl) derivatives of the reactive amine 1,3-benzenedimethanamine (1,3-BDMA). METHODS:We describe the...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12652

    authors: Pesonen M,Kuuliala O,Suomela S,Aalto-Korte K

    更新日期:2016-12-01 00:00:00

  • Epidemiological, clinical and allergological observations on pompholyx.

    abstract::We have studied a group of 104 patients with pompholyx, to investigate the relationship between allergological factors and its etiopathogenesis. The following examinations were performed: blood sampling (routine tests and IgE levels), allergological tests (patch, prick, intradermal, and oral provovation tests with nic...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00862.x

    authors: Lodi A,Betti R,Chiarelli G,Urbani CE,Crosti C

    更新日期:1992-01-01 00:00:00

  • Photocontact dermatitis to hydrocortisone.

    abstract::A patient was found to have a delayed positive patch test to hydrocortisone on multiple testing. This proved to be due to a photoallergy with an action spectrum in the UV-A range. The patient coincidently had a polymorphous light eruption in the UV-B range. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1978.tb03845.x

    authors: Rietschel RL

    更新日期:1978-12-01 00:00:00

  • Self-reported skin disease in hydrotherapists working in swimming pools.

    abstract::The aim of our study was to investigate the risk and characteristics of self-reported skin diseases among hydrotherapists. We attempted to contact 400 adults who participated in 1 of 2 training courses. 248 were reached and 190 of them (76.6%) completed the questionnaires. The data were collected by means of a telepho...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2005.00699.x

    authors: Lazarov A,Nevo K,Pardo A,Froom P

    更新日期:2005-12-01 00:00:00

  • Consequences of occupational food-related hand dermatoses with a focus on protein contact dermatitis.

    abstract:BACKGROUND:Protein contact dermatitis is a frequent disorder among hand eczema patients who have occupational food contact. Knowledge about the consequences of having protein contact dermatitis is lacking. OBJECTIVES:To investigate the consequences of having occupational skin disease on the hands resulting from food h...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2012.02101.x

    authors: Vester L,Thyssen JP,Menné T,Johansen JD

    更新日期:2012-12-01 00:00:00

  • Frictional hyperkeratotic hand dermatitis responding to Grenz ray therapy.

    abstract::Frictional hyperkeratotic hand dermatitis (FHHD) is an unusual form of chronic eczema relating to repeated frictional trauma. This form of hand eczema is often occupationally related and recalcitrant to therapy. We describe the case of FHHD in a 48-year-old dermatologic surgeon. The eruption was resistant to all topic...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.01152.x

    authors: Walling HW,Swick BL,Storrs FJ,Boddicker ME

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  • Sensitization to olive oil (olea europeae).

    abstract::Sensitization to olive oil is seldom reported in the literature. By use of epicutaneous tests a delayed type of hypersensitivity to pure freshly-prepared olive oil could be demonstrated in two patients. Patch tests with certain major constituents of olive oil; the methyl ester of linoleic acid, the glyceryl ester of p...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1981.tb04086.x

    authors: van Joost T,Smitt JH,van Ketel WG

    更新日期:1981-11-01 00:00:00

  • Quantification of para-phenylenediamine and heavy metals in henna dye.

    abstract::Henna (Lawsonia inermis, family Lythraceae) is a shrub cultivated in India, Sri Lanka and North Africa and contains the active dye lawsone (2-hydroxy-1,4-naphthoquinone). Henna dye is obtained from the dried leaves, which are powdered and mixed with oil or water and are used to prepare hair and body dyes. Temporary he...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2006.00845.x

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    更新日期:2006-07-01 00:00:00

  • Purpuric contact dermatitis from black rubber chemicals.

    abstract::Black rubber chemicals are capable of causing an allergic contact dermatitis, in some cases associated with a purpuric capillaritis. A typical case of such a purpuric reaction is described in a man sensitive to black rubber chemicals. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1988.tb04504.x

    authors: Roed-Petersen J,Clemmensen OJ,Menné T,Larsen E

    更新日期:1988-03-01 00:00:00

  • Polyvinyl chloride work boots in the management of shoe dermatitis in industrial workers.

    abstract::A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04860.x

    authors: Mathias CG,Maibach HI

    更新日期:1979-07-01 00:00:00

  • Allergic contact dermatitis of the lip margins from para-tertiary-butylphenol in a lip liner.

    abstract::We describe the use of gas chromatography with mass spectrometry (GC-MS) in the investigation of a case of allergic contact dermatitis of the lip margins caused by a lip liner. Patch testing identified sensitization to para-tertiary-butylphenol-formaldehyde resin (PTBP-FR), a resin glue frequently used in leather work...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1993.tb03375.x

    authors: Angelini E,Marinaro C,Carrozzo AM,Bianchi L,Delogu A,Giannello G,Nini G

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  • Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01425.x

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  • A hand immersion test under laboratory-controlled usage conditions: the need for sensitive and controlled assessment methods.

    abstract::Exaggerated test conditions were frequently used to investigate the cutaneous tolerance of detergent products in the past. As the sensitivity of newly designed biometric methods is steadily improving, the trend towards more realistic test conditions should be encouraged. A hand immersion test under laboratory-controll...

    journal_title:Contact dermatitis

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1600-0536.1999.tb06010.x

    authors: Paye M,Gomes G,Zerweck CR,Piérard GE,Grove GL

    更新日期:1999-03-01 00:00:00

  • Fragrance allergy in patients with hand eczema - a clinical study.

    abstract::Fragrance allergy and hand eczema are both common among dermatological patients. Fragrance mix (FM) and its constituents have a recognized relevance to exposure to fine fragrances and cosmetic products. Based on extensive chemical analysis and database search, a new selection of fragrances was established, including 1...

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    doi:10.1034/j.1600-0536.2003.00133.x

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    更新日期:2003-06-01 00:00:00

  • Anaphylaxis due to formaldehyde released from root-canal disinfectant.

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    pub_type: 杂志文章,评审

    doi:10.1034/j.1600-0536.2002.470405.x

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    更新日期:2002-10-01 00:00:00

  • The Scandinavian standard photopatch test procedure.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1982.tb04174.x

    authors: Jansén CT,Wennersten G,Rystedt I,Thune P,Brodthagen H

    更新日期:1982-05-01 00:00:00