2-methoxy-6-pentyl-1,4-dihydroxybenzene (miconidin) from Primula obconica: a possible allergen?

abstract：BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...

journal_title：Contact dermatitis

authors： Corazza M,Borghi A,Gallo R,Schena D,Pigatto P,Lauriola MM,Guarneri F,Stingeni L,Vincenzi C,Foti C,Virgili A

更新日期：2014-02-01 00:00:00

abstract：:Exaggerated test conditions were frequently used to investigate the cutaneous tolerance of detergent products in the past. As the sensitivity of newly designed biometric methods is steadily improving, the trend towards more realistic test conditions should be encouraged. A hand immersion test under laboratory-controll...

journal_title：Contact dermatitis

authors： Paye M,Gomes G,Zerweck CR,Piérard GE,Grove GL

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:In 2016, dermatologists in Finland suspected contact allergy in several patients using moisturizers under the trade name Apobase®. Following a formulation change, Phenostat™, which is a mixture of phenoxyethanol, caprylhydroxamic acid, and methylpropanediol, was used as a preservative in Apobase® moisturizer...

journal_title：Contact dermatitis

authors： Ackermann L,Virtanen H,Korhonen L,Laukkanen A,Huilaja L,Riekki R,Hasan T

更新日期：2017-09-01 00:00:00

abstract：:Patch testing is an invaluable tool for the experimental induction of acute irritant contact dermatitis (ICD), with a variety of chamber systems available for use. Ideally, the inflammatory reactions produced should be of uniform intensity across the test area, thereby facilitating grading of the response and tissue s...

journal_title：Contact dermatitis

authors： Nicholson M,Willis CM

更新日期：1999-11-01 00:00:00

abstract：:The aim of the study is to describe the ability of patients with allergic contact dermatitis to avoid exposure to allergens in cosmetics. The study is a questionnaire survey among 382 patients with contact allergy to preservatives and fragrances, included from 3 dermatological clinics. The questionnaire included quest...

journal_title：Contact dermatitis

authors： Noiesen E,Munk MD,Larsen K,Johansen JD,Agner T

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Foot eczema often occurs in combination with hand eczema. However, in contrast to the situation with hand eczema, knowledge about foot eczema is scarce, especially in occupational settings. OBJECTIVE:To evaluate the prevalence of foot eczema and associated factors in patients with hand eczema taking part in...

journal_title：Contact dermatitis

authors： Brans R,Hübner A,Gediga G,John SM

更新日期：2015-08-01 00:00:00

abstract：:Fragrance substances represent a very diverse group of chemicals; a proportion of them are associated with the ability to cause allergic reactions in the skin. Efforts to find substitute materials are hindered by the need to undertake animal testing for determining both skin sensitization hazard and potency. One strat...

journal_title：Contact dermatitis

authors： Patlewicz GY,Basketter DA,Pease CK,Wilson K,Wright ZM,Roberts DW,Bernard G,Arnau EG,Lepoittevin JP

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:On skin contact, nickel accumulates in the stratum corneum, where it is probably bound to proteins and amino acids. One probable contributor is filaggrin, which binds nickel avidly. Filaggrin gene (FLG) null mutations lead to a complete lack of filaggrin production from the affected allele, and have been ass...

journal_title：Contact dermatitis

authors： Ross-Hansen K,Johansen JD,Vølund A,Menné T,Thyssen JP

更新日期：2014-07-01 00:00:00

abstract：:Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's ...

journal_title：Contact dermatitis

authors： Fenner J,Hadi A,Yeh L,Silverberg N

更新日期：2020-05-01 00:00:00

abstract：:The validity of questionnaire answers with respect to hand eczema was investigated. Car mechanics, dentists and office workers answered a questionnaire on the occurrence of hand eczema on any occasion during the past 12 months. "Yes"-responders and a random sample of "no"-responders were subsequently interviewed and e...

journal_title：Contact dermatitis

authors： Meding B,Barregård L

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Several studies have assessed the effect of patient education regarding hand eczema (HE) severity and quality of life. Few studies, however, have evaluated patients' knowledge. OBJECTIVES:To examine knowledge of skin protection in HE patients following a guided talk, and to identify variables associated wit...

journal_title：Contact dermatitis

authors： Topal Y,Agner T,van der Heiden J,Ebbehøj NE,Clemmensen KKB

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to determine the types of side-effects occurring and for how long they lasted in a group of patients with side-effects assessed to be caused by resin-based materials. METHODS:A total of 618 reports were received by the Swedish National Register of Side-Effects to Dental Mater...

journal_title：Contact dermatitis

authors： Tillberg A,Stenberg B,Berglund A

更新日期：2009-12-01 00:00:00

abstract：:Bullous dermatitis, which resolved leaving hyperpigmentation and which was clinically consistent with phytophotodermatitis , affected the skin of the neck of 2 individuals who wore Hawaiian leis (as neck garlands ) made of the fruits of Pelea anisata . In a Daniels culture plate system portions of the fruits showed ph...

journal_title：Contact dermatitis

authors： Elpern DJ,Mitchell JC

更新日期：1984-04-01 00:00:00

abstract：:A cohort of initially 111 office apprentices was prospectively followed for the duration of their training (2 and 3 years, respectively). The point prevalence of (slight) irritant or atopic hand eczema was 18.9% in the initial and 25.0% in the final examinations. Altogether, 37 cases of (slight) hand eczema were noted...

journal_title：Contact dermatitis

authors： Uter W,Pfahlberg A,Gefeller O,Schwanitz HJ

更新日期：1998-02-01 00:00:00

abstract：:Although hand hygiene is an important and inexpensive measure to prevent nosocomial infections in clinical settings, the compliance of healthcare workers remains low. In Europe, alcoholic hand disinfection is first choice, but there exists a limited user acceptability due to estimated adverse effects on skin condition...

journal_title：Contact dermatitis

authors： Houben E,De Paepe K,Rogiers V

更新日期：2006-05-01 00:00:00

abstract：:The present report describes experimental studies on the proteolytic activity of the secretion on the surface of okra pods and the allergenicity of okra components, to clarify the etiology of skin lesions due to okra. Proteolytic activity was detected on the surface of immature okra pods and seemed to be sufficient to...

journal_title：Contact dermatitis

authors： Manda F,Tadera K,Aoyama K

更新日期：1992-02-01 00:00:00

abstract：:Cheilitis granulomatosa (CG) is a rare disorder of unknown origin, which is characterized clinically by painless, recurrent or persistent swelling of 1 or both lips. Betel quids, composed of betel nuts (seeds of the Areca catechu), slake lime, and Piper betel leaf/or Piper betel inflorescence, are widely used in Asia ...

journal_title：Contact dermatitis

authors： Chiu CS,Tsai YL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. OBJECTIVES:To study patterns of simultaneous patch test reactions to thiurams and dithiocarbamates at the Finnish Institute of Occupational Health in 1991-2015. METHODS:We searched the patch test files for patients with...

journal_title：Contact dermatitis

authors： Aalto-Korte K,Pesonen M

更新日期：2016-12-01 00:00:00

abstract：:Recognizing the growing need for international standardization of photopatch testing techniques, a standard procedure has been used by Scandinavian dermatological clinics since January 1980. The set-up includes a standardized patient examination scheme, including phototest evaluation of the patient's UVA- and UVB-sens...

journal_title：Contact dermatitis

authors： Jansén CT,Wennersten G,Rystedt I,Thune P,Brodthagen H

更新日期：1982-05-01 00:00:00

abstract：:Henna (Lawsonia inermis, family Lythraceae) is a shrub cultivated in India, Sri Lanka and North Africa and contains the active dye lawsone (2-hydroxy-1,4-naphthoquinone). Henna dye is obtained from the dried leaves, which are powdered and mixed with oil or water and are used to prepare hair and body dyes. Temporary he...

journal_title：Contact dermatitis

authors： Kang IJ,Lee MH

更新日期：2006-07-01 00:00:00

abstract：:Musk ambrette has become one of the commonest photosensitizers in many countries and is the cause of persistent light reactions in many patients. A simple method is presented for qualitative analysis for musk ambrette and other nitromusks in colognes using thin-layer chromatography with toluene as carrier solvent and ...

journal_title：Contact dermatitis

authors： Goh CL,Kwok SF

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Environmental exposure and personal susceptibility both contribute to the development of hand eczema. In this study, we investigated the effect of loss-of-function mutations in the filaggrin gene (FLG), atopic dermatitis and wet work exposure on the development of hand eczema in apprentice nurses....

journal_title：Contact dermatitis

authors： Visser MJ,Verberk MM,Campbell LE,McLean WH,Calkoen F,Bakker JG,van Dijk FJ,Bos JD,Kezic S

更新日期：2014-03-01 00:00:00

abstract：:Sensitization rates are influenced by sex and age. Crude rates from different departments cannot be compared without taking into account these variables. However, the influence of sex and age has never been considered quantitatively. In 2 hypothetical populations with identical age-specific sensitizations rates, but d...

journal_title：Contact dermatitis

authors： Schnuch A

更新日期：1996-06-01 00:00:00

abstract：:Among patients consecutively patch tested at St John's from 1984-1989, the prevalence rate of formaldehyde sensitivity was 2.2% for men and 3.7% for women. During these 6 years, 117 women were primarily sensitized by formaldehyde, of whom 61 (52%) had hand eczema. Exposure was occupational in 12% and domestic in 88%. ...

journal_title：Contact dermatitis

authors： Cronin E

更新日期：1991-11-01 00:00:00

abstract：:Prevention of NiSO4 induced allergic contact dermatitis (ACD) using ZnSO4 in drinking water was studied in a guinea pig model. Without ZnSO4 interventions, nickel (Ni)-exposure resulted in significantly higher (p less than 0.05) stimulation indices (SIs) as compared to non-exposed controls, using NiSO4 as an allergen ...

journal_title：Contact dermatitis

authors： Warner RD,Dorn CR,Blakeslee JR,Gerken DF,Gordon JC,Angrick EJ

更新日期：1988-08-01 00:00:00

abstract：:Predictive guinea pig sensitization studies have been performed with commercial and purified 1H-benzotriazole. In only 3 animals, induced and challenged according to the maximization protocol with more than 100 times the normal use concentration, were slight erythemas elicited with the commercial grade of benzotriazol...

journal_title：Contact dermatitis

authors： Maurer T,Meier F

更新日期：1984-03-01 00:00:00

abstract：:During the 2-year period 1976--1977, seven patients were studied with primary irritant dermatitis from topical preparations containing clioquinol. During the same period contact hypersensitivity to the compound was recorded in 35 eczema patients. Six of the seven patients with clioquinol irritancy had used creams cont...

journal_title：Contact dermatitis

authors： Kero M,Hannuksela M,Sothman A

更新日期：1979-03-01 00:00:00

abstract：:To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...

journal_title：Contact dermatitis

authors： Thyssen JP,Giménez-Arnau E,Lepoittevin JP,Menné T,Boman A,Schnuch A

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:While allergy to food proteins is almost exclusively found in association with atopy, it has been our experience that contact allergy to some contact allergens/haptens with both cutaneous and gastrointestinal exposures is reduced in atopic dermatitis (AD) patients as a group. OBJECTIVE:To assess the contact...

journal_title：Contact dermatitis

authors： McFadden JP,White JM

更新日期：2008-05-01 00:00:00

abstract：:1310 patients were routinely patch tested with a paratertiary-butylphenol-formaldehyde resin (PTBP-F-R), a resol resin based on phenol and formaldehyde (P-F-R-2), and a mixture of these 2 resins. Approximately 2.5 times more patients with contact allergy to phenol-formaldehyde resins were diagnosed when routinely patc...

journal_title：Contact dermatitis

authors： Bruze M

更新日期：1988-08-01 00:00:00