The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals. Part I.

Abstract:

:To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Thyssen JP,Giménez-Arnau E,Lepoittevin JP,Menné T,Boman A,Schnuch A

doi

10.1111/j.1600-0536.2011.02004_2.x

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

11-24

eissn

0105-1873

issn

1600-0536

journal_volume

66 Suppl 1

pub_type

杂志文章,评审
  • Contact dermatitis in hairdressers' clients.

    abstract::The aim of our study was to report the frequency of sensitization to hairdressing allergens in a group of patients with contact dermatitis, in whom previous treatments with hair dyes or permanent wave solutions were suspected to be the cause. 49 of 261 hairdressers' clients (18.7%), who were patch tested with the hair...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb00893.x

    authors: Guerra L,Bardazzi F,Tosti A

    更新日期:1992-02-01 00:00:00

  • Patch test reactions to metal salts in patients with oral mucosal lesions associated with amalgam restorations.

    abstract::Patch testing with various metal salts was performed in patients with oral mucosal lesions associated with amalgam restorations, by using polypropylene-coated aluminium discs. Positive reactions to mercuric chloride were obtained in 5/12 (42%) of these patients, but only in 1/11 patients (9%) with oral mucosal lesions...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb05245.x

    authors: Nordlind K,Lidén S

    更新日期:1992-09-01 00:00:00

  • Contact sensitivity to flavourings and perfumes in atopic dermatitis.

    abstract::16 children with atopic dermatitis and 4 nonatopics were skin tested with flavourings and perfumes. Immediate reactions to balsam of Peru and fragrance-mix were found in 9 atopics, and none among nonatopics. An irritant is more probable than an immunologic mechanism. Allergen solutions should probably be assayed at a ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1992.tb05196.x

    authors: Abifadel R,Mortureux P,Perromat M,Ducombs G,Taieb A

    更新日期:1992-07-01 00:00:00

  • Sickness absence due to occupational dermatoses in a prefabrication construction factory.

    abstract::In a study of sickness absence due to occupational dermatoses among 360 construction workers in a prefabrication construction factory in 1984, we found 3 workers with allergic contact dermatitis from chromate in cement who required medical leave. There were 5 sickness absence spells due to occupational dermatoses and ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1986.tb01257.x

    authors: Goh CL

    更新日期:1986-07-01 00:00:00

  • Higher allergenicity of high molecular weight hydrolysed wheat protein in cosmetics for percutaneous sensitization.

    abstract:BACKGROUND:Wheat protein derivatives are used in a variety of products worldwide. Gluten is commercially used 'as is' or with modifications such as hydrolysis, which is carried out to overcome its insolubility. Several cases of contact urticaria following exposure to hydrolysed wheat protein (HWP) in cosmetics or of an...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2012.02168.x

    authors: Chinuki Y,Takahashi H,Dekio I,Kaneko S,Tokuda R,Nagao M,Fujisawa T,Morita E

    更新日期:2013-02-01 00:00:00

  • Cinnamic aldehyde in toothpaste. 1. Clinical aspects and patch tests.

    abstract::Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly-formulated 'spicy' toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire a...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1975.tb05330.x

    authors: Magnusson B,Wilkinson DS

    更新日期:1975-01-01 00:00:00

  • Skin irritant reactivity following experimental cumulative irritant contact dermatitis.

    abstract::Despite the frequency of irritant contact dermatitis, very little is known about the duration of barrier function impairment following cumulative irritant contact dermatitis. We studied post-irritation irritant reactivity by assessing the response to SLS irritation in previously irritated sites. Cumulative irritant co...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1994.tb00725.x

    authors: Widmer J,Elsner P,Burg G

    更新日期:1994-01-01 00:00:00

  • Structure-activity relationships in allergic contact dermatitis induced by methacrylates. Studies of the influence of side-chain length of methacrylates.

    abstract::Some methacrylates are known to be strong contact sensitizers. To determine the effect of side-chain length on sensitizing potential, we examined 11 derivatives with linear side chains from C1 to C18 in an experimental sensitization test in guinea pigs. The results showed an increase in the sensitizing potential with ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1999.tb05971.x

    authors: Kanazawa Y,Yoshida T,Kojima K

    更新日期:1999-01-01 00:00:00

  • Prevalence and 1-year outcome of facial allergic contact dermatitis in patients patch tested in a university hospital.

    abstract::Little is known about the prognosis of facial allergic contact dermatitis (FACD). The objective of the study was to investigate the prevalence and 1-year outcome of FACD in patients patch tested. 655 consecutive patients patch tested with European standard series in Peking University Hospital in a 2-year period were s...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.01198.x

    authors: Li LF,Liu G,Wang J

    更新日期:2007-09-01 00:00:00

  • p-Phenylenediamine exposure in real life - a case-control study on sensitization rate, mode and elicitation reactions in the northern Netherlands.

    abstract:BACKGROUND:The prevalence of p-phenylenediamine (PPD) sensitization is 4% in the patch tested population and varies between zero and 1.5% in the general population. Hair dye is a recognised sensitization source. OBJECTIVES:To define the prevalence rates of PPD sensitization in the general and patch tested populations ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.12354

    authors: Vogel TA,Coenraads PJ,Bijkersma LM,Vermeulen KM,Schuttelaar ML,EDEN Fragrance Study Group.

    更新日期:2015-06-01 00:00:00

  • Self-reported skin disease in hydrotherapists working in swimming pools.

    abstract::The aim of our study was to investigate the risk and characteristics of self-reported skin diseases among hydrotherapists. We attempted to contact 400 adults who participated in 1 of 2 training courses. 248 were reached and 190 of them (76.6%) completed the questionnaires. The data were collected by means of a telepho...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2005.00699.x

    authors: Lazarov A,Nevo K,Pardo A,Froom P

    更新日期:2005-12-01 00:00:00

  • Airborne contact dermatitis in gaitas (flageolets) constructors after exposure to sawdust of caviuna.

    abstract::Exotic wood species are used in the manufacture of furniture, musical instruments, tool handles, and other wooden items. Exposure to sawdust of the wood can produce dermatitis on exposed areas in woodworkers. We studied 7 patients, gaitas constructors who used caviuna wood to make their instruments. They developed der...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2007.01095.x

    authors: Rojas-Hijazo B,Lezaun A,Hausen BM,Segura N,Mar Garcés M,Colás C

    更新日期:2007-05-01 00:00:00

  • Photopatch test method: influence of type of irradiation and value of day-7 reading.

    abstract::118 consecutive patients were photopatch tested with 5J UVA and 10mJ UVB. In addition, day 7 readings were taken. Testing with UVB and performing late readings conferred no advantage. The current recommendations of the British Photodermatology Group regarding photopatch testing remain the most recent guide to photopat...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2001.440502.x

    authors: Pollock B,Wilkinson SM

    更新日期:2001-05-01 00:00:00

  • Patch testing of 490 patients in Hong Kong.

    abstract::Patch testing, using European standard allergens and suspected causative substances brought in by patients, was carried out in 490 patients with eczema in Hong Kong and 437 completed the test. Before patch testing, 244, 141 and 105 patients were diagnosed as having contact dermatitis, endogenous eczema and unclassifie...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02261.x

    authors: Lee TY,Lam TH

    更新日期:1996-07-01 00:00:00

  • Terfenadine does not inhibit non-immunologic contact urticaria.

    abstract::To investigate the mechanisms of non-immunologic contact urticaria (NICU), the effect of 120 mg of terfenadine (H1-antagonist) on contact reactions to methyl nicotinate, diethyl fumarate, benzoic acid, cinnamic acid, cinnamic aldehyde and dimethyl sulfoxide was studied in 20 subjects. Erythema and edema were observed ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1987.tb01429.x

    authors: Lahti A

    更新日期:1987-04-01 00:00:00

  • Chemical analysis of monomers in epoxy resins based on bisphenols F and A.

    abstract::Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.0105-1873.2004.00319.x

    authors: Pontén A,Zimerson E,Sörensen O,Bruze M

    更新日期:2004-05-01 00:00:00

  • Age distribution of the incidence of contact sensitivity to standard allergens.

    abstract::The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1979.tb04910.x

    authors: Sugai T,Takagi T,Yamamoto S,Takahashi Y

    更新日期:1979-12-01 00:00:00

  • Contact allergy and allergic contact dermatitis caused by lavender: A retrospective study from an Australian clinic.

    abstract:BACKGROUND:Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer, and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES:To report our experience with contact allergy and ACD caused by lavender, and to rai...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13247

    authors: Bingham LJ,Tam MM,Palmer AM,Cahill JL,Nixon RL

    更新日期:2019-07-01 00:00:00

  • Sensitivity to some rubber additives.

    abstract::The frequency of positive patch tests to 13 rubber accelerators in Poland was recorded. Of particular interest was the relatively large group of patients positive to several, mostly chemically unrelated, accelerators. The mechanism of this multiple sensitivity is discussed. Positive tests to N-isopropyl-N-phenyl-p-phe...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1976.tb02974.x

    authors: Rudzki E,Ostaszewski K,Grzywa Z,Kozlowska A

    更新日期:1976-02-01 00:00:00

  • Guidelines for transepidermal water loss (TEWL) measurement. A report from the Standardization Group of the European Society of Contact Dermatitis.

    abstract::This report reviews individual-related variables, environment-related variables and instrument-related variables, with a focus on the Evaporimeter EP1 (ServoMed). Start-up and use is described, and guidelines for good laboratory practice given. ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1990.tb01553.x

    authors: Pinnagoda J,Tupker RA,Agner T,Serup J

    更新日期:1990-03-01 00:00:00

  • Contact allergy to Disperse Blue 106 and Disperse Blue 124 in German and Austrian patients, 1995 to 1999.

    abstract::Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章,多中心研究

    doi:10.1034/j.1600-0536.2001.044003173.x

    authors: Uter W,Geier J,Lessmann H,Hausen BM,IVDK and the German Contact Dermatitis Research Grooup. Information Network of Departments of Dermatology.

    更新日期:2001-03-01 00:00:00

  • Hand eczema among Hong Kong nurses: a self-report questionnaire survey conducted in a regional hospital.

    abstract:BACKGROUND:Hand eczema is common in the nursing profession, and has been reported widely in various parts of the world. OBJECTIVES:The aim of this study was to determine the prevalence and severity of hand eczema among nurses working in a regional hospital in Hong Kong, as well as its psychosocial impact and any possi...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2011.01961.x

    authors: Luk NM,Lee HC,Luk CK,Cheung YY,Chang MC,Chao VK,Ng SC,Tang LS

    更新日期:2011-12-01 00:00:00

  • Occupational contact dermatitis among rubber workers.

    abstract::The occurrence of occupational contact dermatitis among workers in a rubber factory from 1976 to 1980 was studied. Insurance compensation was paid to 50 workers with dermatitis. 21 of the cases were allergic and 27 toxic contact dermatitis, giving a contact dermatitis frequency of 5.6/1000 workers. Paraphenylenediamin...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1982.tb04259.x

    authors: Kilpikari I

    更新日期:1982-11-01 00:00:00

  • Olive oil--contact sensitizer or irritant?

    abstract::Adverse cutaneous reactions to topically applied olive oil are seldom reported, and positive patch tests to it are mostly regarded as allergic. To evaluate such "positive" patch test reactions, 77 female (mean age: 44 years) and 23 male eczema patients (mean age: 46 years) were prospectively patch tested with freshly ...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1997.tb00914.x

    authors: Kränke B,Komericki P,Aberer W

    更新日期:1997-01-01 00:00:00

  • Clinical scoring and biophysical evaluation of nasolabial skin barrier damage caused by rhinorrhea.

    abstract:BACKGROUND:An acute viral cold is a very common illness and is characterized by sneezing and a runny nose. Because of rhinorrhea and frequent use of handkerchiefs, the skin around the nose feels uncomfortably dry and flaky. OBJECTIVES/METHODS:To evaluate the nasolabial skin barrier impairment, 14 female volunteers wit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2008.01425.x

    authors: Houben E,Adam R,Hachem JP,Roseeuw D,Rogiers V,De Paepe K

    更新日期:2008-11-01 00:00:00

  • Olive oil as a cause of contact allergy in patients with venous eczema, and occupationally.

    abstract::From 1985 to 1989, 13 cases of contact allergy to olive oil have been identified in the Departments of Dermatology of Kristianstad and Ostersund Hospitals. Known components of olive oil could not be proved to be the cause of the allergy. This high number of patients with contact allergy to olive oil and possible expla...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1990.tb03226.x

    authors: Malmkvist Padoan S,Pettersson A,Svensson A

    更新日期:1990-08-01 00:00:00

  • Hand eczema patients' knowledge of skin protection following a guided talk-A retrospective study with a follow-up questionnaire.

    abstract:BACKGROUND:Several studies have assessed the effect of patient education regarding hand eczema (HE) severity and quality of life. Few studies, however, have evaluated patients' knowledge. OBJECTIVES:To examine knowledge of skin protection in HE patients following a guided talk, and to identify variables associated wit...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/cod.13264

    authors: Topal Y,Agner T,van der Heiden J,Ebbehøj NE,Clemmensen KKB

    更新日期:2019-08-01 00:00:00

  • Sodium-lauryl-sulphate-induced cutaneous irritation. Comparison of white and Hispanic subjects.

    abstract::Reactivity of white and hispanic skin after exposure to sodium lauryl sulphate (SLS) has been investigated. The tests were performed on the back as follows: untreated skin, skin pre-treated with short-term occlusion and delipidized skin. Irritant reactions were induced by applying 0.5% and 2.0% SLS via Finn chamber pa...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1988.tb05512.x

    authors: Berardesca E,Maibach HI

    更新日期:1988-08-01 00:00:00

  • Antigen-presenting cells and keratinocytes express interleukin-12 in allergic contact dermatitis.

    abstract::Interleukin-12 (IL-12) has previously been suggested as playing a major rôle in the activation of cytotoxic lymphocytes. Recent reports indicate that cytotoxic CD8+ cells are critically involved in the elicitation phase of contact hypersensitivity reactions. In this study, the in situ expression of IL-12 was investiga...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1034/j.1600-0536.2000.042001018.x

    authors: Yawalkar N,Egli F,Brand CU,Pichler WJ,Braathen LR

    更新日期:2000-01-01 00:00:00

  • Late skin reaction to iodixanol (Visipaque): clinical manifestations, patch test study, and histopathological evaluation.

    abstract::Late reactions to iodinated contrast media are frequent. Cutaneous manifestations are the commonest, in which maculopapular exanthema, a type of cutaneous presentation, is widespread. Controversy exists about the utility of the skin test in the management of these reactions. The aim of this study is to analyse the cli...

    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.2006.00957.x

    authors: Delgado-Jimenez Y,Perez-Gala S,Aragüés M,Sanchez-Perez J,Garcia-Diez A

    更新日期:2006-12-01 00:00:00