Skin irritant reactivity following experimental cumulative irritant contact dermatitis.

abstract：:The occurrence of occupational contact dermatitis among workers in a rubber factory from 1976 to 1980 was studied. Insurance compensation was paid to 50 workers with dermatitis. 21 of the cases were allergic and 27 toxic contact dermatitis, giving a contact dermatitis frequency of 5.6/1000 workers. Paraphenylenediamin...

journal_title：Contact dermatitis

authors： Kilpikari I

更新日期：1982-11-01 00:00:00

abstract：:The low-molecular-weight phenols 2-methylol phenol (2-MP), 4-methylol phenol (4-MP), 2,4,6-trimethylol phenol (2,4,6-MP), 3-methylol phenol (3-MP), 2,4-dimethylol phenol (2,4-MP), and 2,6-dimethylol phenol (2,6-MP) are contact sensitizers in resins based on phenol and formaldehyde (P-F-R). Other chemically related low...

journal_title：Contact dermatitis

authors： Bruze M,Zimerson E

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Contact allergy prevalence rates change over time as a result of variations in allergen exposure. Data from patch test clinics are often used as markers for allergy trends. OBJECTIVES:The aim of the present retrospective study was to describe trends in rates of sensitization to allergens in the Swedish base...

journal_title：Contact dermatitis

authors： Fall S,Bruze M,Isaksson M,Lidén C,Matura M,Stenberg B,Lindberg M

更新日期：2015-05-01 00:00:00

abstract：:The possible interference of neighbouring allergic patch-test reactions is still an open question. In this study, we investigated whether there is a distance-related mutual modification of neighbouring allergic patch-test reactions to nickel sulfate and potassium dichromate. We used a double-blind multicentre study de...

journal_title：Contact dermatitis

authors： Brasch J,Kreilgård B,Henseler T,Aberer W,Fuchs T,Pflüger R,Hoeck U,Gefeller O

更新日期：2000-09-01 00:00:00

abstract：:In two cases, occupational contact dermatitis was found to be due to chicory (Cichorium) used as a salad plant. In one of the two cases, contact sensitivity to letuce (Lactuca) was also observed. The sesquiterpene lactones of the plant may be the allergens. ...

journal_title：Contact dermatitis

authors： Friis B,Hjorth N,Vail JT Jr,Mitchell JC

更新日期：1975-10-01 00:00:00

abstract：:Between 1995 and 1999, 1986 patients were tested in the 31 participating centres of the Information Network of Departments of Dermatology (IVDK), all of them members of the German Contact Dermatitis Research Group, with a textile dyes series containing Disperse Blue (DB) 106 and 124, and since 1997 also with a mix of ...

journal_title：Contact dermatitis

authors： Uter W,Geier J,Lessmann H,Hausen BM,IVDK and the German Contact Dermatitis Research Grooup. Information Network of Departments of Dermatology.

更新日期：2001-03-01 00:00:00

abstract：:Serum from guinea pigs exposed to a single high dose of UVB and from controls was injected into the spleen of normal animals 5 days prior to sensitization. When 1.0 ml was transferred 4.5 h after irradiation, immunosuppression was obtained. Transfer of 1.5 ml of serum 2.5 h after irradiation failed to induce immunosup...

journal_title：Contact dermatitis

authors： Christensen OB,Christensen MB,Wall LM

更新日期：1987-04-01 00:00:00

abstract：:Hydrolyzed wheat protein is used as an additive in several cosmetic products. We present a case of contact allergy to hydrolyzed wheat protein found in a cosmetic cream and highlight this additive is a potential allergen. ...

journal_title：Contact dermatitis

authors： Hann S,Hughes M,Stone N

更新日期：2007-02-01 00:00:00

abstract：:A 45-year-old woman developed dermatitis of the face after she applied a cosmetic package comprising day and night creams. Patch tests were performed with the British Contact Dermatitis Society (BCDS) standard, bases + preservatives, and cosmetic series in addition to samples of both creams and the individual constitu...

journal_title：Contact dermatitis

authors： Malik MM,Hegarty MA,Bourke JF

更新日期：2007-04-01 00:00:00

abstract：:Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to chromium from leather products includes both Cr(III) and Cr(VI). We have determined and compared the minimum elicitation threshold (MET) concentration for Cr(III) and Cr(VI) in Cr(VI)-sensitive patients. In addition,...

journal_title：Contact dermatitis

authors： Hansen MB,Johansen JD,Menné T

更新日期：2003-10-01 00:00:00

abstract：:The purpose of this study was to investigate the role of contact hypersensitivity (CHS) in adult widespread eczema (WE) and to analyse the aetiology of WE. 108 consecutive adult WE patients were patch tested. 352 patients with suspected localized allergic contact dermatitis (ACD) tested in the same period served as a ...

journal_title：Contact dermatitis

authors： Li LF,Wang J

更新日期：2002-12-01 00:00:00

abstract：:Predictive guinea pig sensitization studies have been performed with commercial and purified 1H-benzotriazole. In only 3 animals, induced and challenged according to the maximization protocol with more than 100 times the normal use concentration, were slight erythemas elicited with the commercial grade of benzotriazol...

journal_title：Contact dermatitis

authors： Maurer T,Meier F

更新日期：1984-03-01 00:00:00

abstract：:The correct concentration and vehicle for patch testing with corticosteroids is in many instances not known. The results of this study suggest that 1% in ethanol should be the initial choice, unless it can be shown that petrolatum as a vehicle is as sensitive (tixocortol pivalate and budesonide). We could find no evid...

journal_title：Contact dermatitis

authors： Wilkinson SM,Beck MH

更新日期：1996-05-01 00:00:00

abstract：:The sensitization capacity of ethylenediamine was examined by the guinea pig maximization test and compared with dinitrochlorobenzene. Ethylenediamine was found to be a potent sensitizer. An attempt at oral induction of unresponsiveness (tolerance) was unsuccessful with ethylenediamine and DNCB and the same negative r...

journal_title：Contact dermatitis

authors： Eriksen K

更新日期：1979-09-01 00:00:00

abstract：:Hand dermatitis is a prevalent disease with an episodic, chronic character. The use of medical resources is high and is often related to reduced (work) functioning. The burden is therefore high for patients and society. Management of hand dermatitis is often unsatisfactory, and for this reason prevention is important....

journal_title：Contact dermatitis

authors： van Gils RF,Boot CR,van Gils PF,Bruynzeel D,Coenraads PJ,van Mechelen W,Riphagen II,Anema JR

更新日期：2011-02-01 00:00:00

abstract：:Many factors can influence the elicitation of hypersensitivity reactions in guinea pigs and humans. The effect which the vehicle might have on the test response in guinea pigs sensitized with various acrylic compounds, using the "guinea pig maximization test", has been investigated. A marked decrease in the number of ...

journal_title：Contact dermatitis

authors： Björkner B,Niklasson B

更新日期：1984-11-01 00:00:00

abstract：:To investigate the mechanisms of non-immunologic contact urticaria (NICU), the effect of 120 mg of terfenadine (H1-antagonist) on contact reactions to methyl nicotinate, diethyl fumarate, benzoic acid, cinnamic acid, cinnamic aldehyde and dimethyl sulfoxide was studied in 20 subjects. Erythema and edema were observed ...

journal_title：Contact dermatitis

authors： Lahti A

更新日期：1987-04-01 00:00:00

abstract：:Our aim was to quantify and qualify the use of complementary medicine (CM) by patients referred to our contact dermatitis clinic in Leicester, UK. A face-to-face structured questionnaire study was made of 109 consecutive patients referred to the contact dermatitis clinic. 109 such questionnaires were completed. 21/109...

journal_title：Contact dermatitis

authors： Nicolaou N,Johnston GA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Hyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology. OBJECTIVE:To investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE. METHODS:Palmar skin biopsies (lesional and perilesional) were ob...

journal_title：Contact dermatitis

authors： Politiek K,Loman L,Pas HH,Diercks GFH,Lemmink HH,Jan SZ,van den Akker PC,Bolling MC,Schuttelaar MLA

更新日期：2020-09-01 00:00:00

abstract：:We compared the incidence of occupational dermatitis and transepidermal water vapour loss (TEWL) changes from cutting fluids (neat mineral oils) in 24 new machinists with 27 armed forces paramedics (controls) over a 6-month period. The cumulative incidence of occupational dermatitis in positive controls increased from...

journal_title：Contact dermatitis

authors： Goh CL,Gan SL

更新日期：1994-08-01 00:00:00

abstract：:Several factors may be responsible for stomatitis in general and the burning mouth syndrome in particular. The results of patch testing are reported in 4 patients with burning mouth symptoms thought to be due to sensitization to denture material. 2 patients reacted to substances in Luxene dentures, but the allergens w...

journal_title：Contact dermatitis

authors： van Joost T,van Ulsen J,van Loon LA

更新日期：1988-02-01 00:00:00

abstract：:A 30-year-old male developed asthma and pruritus after using an insecticidal spray (Pyrex). The same symptoms appeared with an alcoholic skin disinfectant (M-sprit) and other spirituous preparations denaturated with denatonium benzoate (Bitrex). An open epicutaneous test (20 min) showed wheal and erythema to Pyrex, M-...

journal_title：Contact dermatitis

authors： Björkner B

更新日期：1980-12-01 00:00:00

abstract：:In a study of sickness absence due to occupational dermatoses among 360 construction workers in a prefabrication construction factory in 1984, we found 3 workers with allergic contact dermatitis from chromate in cement who required medical leave. There were 5 sickness absence spells due to occupational dermatoses and ...

journal_title：Contact dermatitis

authors： Goh CL

更新日期：1986-07-01 00:00:00

abstract：:Japanese lacquer is made from the sap of the Japanese lacquer tree (Toxicodendron vernicifluum), a member of the Anacardiacae plant family. Objects painted with this material are described collectively as lacquerware. Both fresh lacquer and lacquerware may evoke allergic contact reactions ascribable to the urushiols c...

journal_title：Contact dermatitis

authors： Kawai K,Nakagawa M,Kawai K,Miyakoshi T,Miyashita K,Asami T

更新日期：1992-10-01 00:00:00

abstract：:Surgical rubber gloves contain allergens derived from natural rubber latex which may sensitize, causing contact urticaria and even systemic reactions. We examined 15 hospital employees allergic to latex surgical gloves, using various skin tests and RAST, to determine the most reliable diagnostic method and to investig...

journal_title：Contact dermatitis

authors： Turjanmaa K,Reunala T,Räsänen L

更新日期：1988-10-01 00:00:00

abstract：:A human 4-h patch test has recently been developed for testing the irritation hazard potential of chemicals. The original method was developed for comparative irritation assessments relative to benchmark irritants using simple statistical tests. In this context, the method has been shown to be robust in intralaborator...

journal_title：Contact dermatitis

authors： Robinson MK,Perkins MA,Basketter DA

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis is known to occur in children with and without atopic dermatitis, but more data are needed on contact sensitization profiles in these two groups. OBJECTIVES:To identify frequent allergens in children with and without atopic dermatitis suspected of having allergic contact dermatit...

journal_title：Contact dermatitis

authors： Lubbes S,Rustemeyer T,Sillevis Smitt JH,Schuttelaar ML,Middelkamp-Hup MA

更新日期：2017-03-01 00:00:00

abstract：:During the last 2 years, we have performed filaggrin genotyping in patients with eczema seen in our hand eczema clinic. We present pictures of healthy and diseased hands from individuals with filaggrin gene (FLG) mutations to describe a clinical entity of hand eczema. We show that xerosis and hyperkeratosis on the dor...

journal_title：Contact dermatitis

authors： Kaae J,Menné T,Carlsen BC,Zachariae C,Thyssen JP

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Alkyl glucosides were not expected to have a sensitizing potential at the concentrations to be used in finished consumer products; however, several contact allergy cases have been published. OBJECTIVES:To report on the patients suffering from allergic contact dermatitis caused by alkyl glucosides observed i...

journal_title：Contact dermatitis

authors： Gijbels D,Timmermans A,Serrano P,Verreycken E,Goossens A

更新日期：2014-03-01 00:00:00

abstract：:Patch testing with chemical irritants almost always produces a striking variability in the intensity of reaction between individuals, even amongst normal, healthy subjects. Whilst there have been many attempts to define factors which predispose to heightened or, conversely, to diminished reactivity, the underlying cel...

journal_title：Contact dermatitis

authors： Willis CM

更新日期：2002-11-01 00:00:00