Variability in responsiveness to irritants: thoughts on possible underlying mechanisms.

abstract：:Patch testing, using European standard allergens and suspected causative substances brought in by patients, was carried out in 490 patients with eczema in Hong Kong and 437 completed the test. Before patch testing, 244, 141 and 105 patients were diagnosed as having contact dermatitis, endogenous eczema and unclassifie...

journal_title：Contact dermatitis

authors： Lee TY,Lam TH

更新日期：1996-07-01 00:00:00

abstract：UNLABELLED:BACKGROUND. Allergens included in the European baseline series should result in positive patch test reactions in at least 1% of a patch test population. Inclusion of local anaesthetics other than benzocaine in the baseline series has previously been debated. OBJECTIVES:To investigate temporal trends of benz...

journal_title：Contact dermatitis

authors： Thyssen JP,Engkilde K,Menné T,Johansen JD

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer, and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES:To report our experience with contact allergy and ACD caused by lavender, and to rai...

journal_title：Contact dermatitis

authors： Bingham LJ,Tam MM,Palmer AM,Cahill JL,Nixon RL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The development of persistent itchy nodules at the injection site following hyposensitization therapy with aluminium-precipitated antigen extract has been described in several reports. Occasionally, contact allergy to aluminium has been reported in individuals with such nodules. OBJECTIVES:To investigate if...

journal_title：Contact dermatitis

authors： Netterlid E,Hindsén M,Björk J,Ekqvist S,Güner N,Henricson KA,Bruze M

更新日期：2009-01-01 00:00:00

abstract：:The epidermal response to 2 different irritants, nonanoic acid (NAA) and sodium lauryl sulfate (SLS), was investigated with 2 different methods. NAA 80% and SLS 4% were applied under occlusion for up to 24 h. Elemental changes were determined in cryosections by x-ray microanalysis. Compared to unexposed skin a signifi...

journal_title：Contact dermatitis

authors： Grängsjö A,Leijon-Kuligowski A,Törmä H,Roomans GM,Lindberg M

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Chromium (Cr) is a common skin sensitizer. The use of Cr(VI) in leather is restricted in the EU, but that of Cr(III) is not. OBJECTIVES:To assess whether prolonged exposure to Cr-tanned leather with mainly Cr(III) release may elicit allergic contact dermatitis in Cr-allergic individuals. METHOD:Ten Cr-alle...

journal_title：Contact dermatitis

authors： Hedberg YS,Erfani B,Matura M,Lidén C

更新日期：2018-05-01 00:00:00

abstract：:Nickel-elicited systemic contact dermatitis is a well-known entity, although it is far less common than allergic contact dermatitis. In most of the cases, the main way of nickel administration is oral. Clinical manifestations are miscellaneous including pompholyx, diffuse exanthema, flexural dermatitis or baboon syndr...

journal_title：Contact dermatitis

authors： Raison-Peyron N,Guillard O,Khalil Z,Guilhou JJ,Guillot B

更新日期：2005-10-01 00:00:00

abstract：:In cases of conjunctivitis associated with the use of soft lenses, delayed hypersensitivity to disinfecting components of the used soft lens liquids has to be considered. In 7/15 patients, positive patch test reactions to merthiolate, chlorhexidine or the soaking solutions were observed. The significance of these find...

journal_title：Contact dermatitis

authors： van Ketel WG,Melzer-van Riemsdijk FA

更新日期：1980-08-01 00:00:00

abstract：:8 cases of contact dermatitis from toluenesulfonamide formaldehyde resin in a nail hardener are presented. Most patients had used nail lacquers containing this resin for many years without trouble, but became sensitized to the resin shortly after the introduction of this particular nail hardener. A hypothesis concerni...

journal_title：Contact dermatitis

authors： de Wit FS,de Groot AC,Weyland JW,Bos JD

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Wheat protein and its derivatives can cause protein contact dermatitis (PCD), which mainly occurs in bakers. Few studies have attempted to identify the allergens responsible for wheat PCD. OBJECTIVES:The aim of this study was to identify allergenic wheat proteins in patients with wheat PCD. METHODS:Water-s...

journal_title：Contact dermatitis

authors： Matsuo H,Uemura M,Yorozuya M,Adachi A,Morita E

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. OBJECTIVES:To study patterns of simultaneous patch test reactions to thiurams and dithiocarbamates at the Finnish Institute of Occupational Health in 1991-2015. METHODS:We searched the patch test files for patients with...

journal_title：Contact dermatitis

authors： Aalto-Korte K,Pesonen M

更新日期：2016-12-01 00:00:00

abstract：:A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...

journal_title：Contact dermatitis

authors： Mathias CG,Maibach HI

更新日期：1979-07-01 00:00:00

abstract：:A human 4-h patch test has recently been developed for testing the irritation hazard potential of chemicals. The original method was developed for comparative irritation assessments relative to benchmark irritants using simple statistical tests. In this context, the method has been shown to be robust in intralaborator...

journal_title：Contact dermatitis

authors： Robinson MK,Perkins MA,Basketter DA

更新日期：1998-04-01 00:00:00

abstract：:The results of patch tests with colophony in the standard series between 1983 and 1987 were analyzed. 5521 patients were tested in the Department of Dermatology, Hamburg, while 354 were tested in other clinics and private practices. Colophony was positive in 2.4% and 11.9%, respectively. Out of 62 patients in the 1st ...

journal_title：Contact dermatitis

authors： Hausen BM,Mohnert J

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Protein contact dermatitis is a frequent disorder among hand eczema patients who have occupational food contact. Knowledge about the consequences of having protein contact dermatitis is lacking. OBJECTIVES:To investigate the consequences of having occupational skin disease on the hands resulting from food h...

journal_title：Contact dermatitis

authors： Vester L,Thyssen JP,Menné T,Johansen JD

更新日期：2012-12-01 00:00:00

abstract：:Fragrance substances represent a very diverse group of chemicals; a proportion of them are associated with the ability to cause allergic reactions in the skin. Efforts to find substitute materials are hindered by the need to undertake animal testing for determining both skin sensitization hazard and potency. One strat...

journal_title：Contact dermatitis

authors： Patlewicz GY,Basketter DA,Pease CK,Wilson K,Wright ZM,Roberts DW,Bernard G,Arnau EG,Lepoittevin JP

更新日期：2004-02-01 00:00:00

abstract：:Allergic contact dermatitis caused by medical devices for diabetes patients has been increasingly described in the literature in the last few years. This article reviews the cases of allergic contact dermatitis caused by insulin pumps and glucose sensors reported since the 1970s, the culprit allergen(s), the results o...

journal_title：Contact dermatitis

authors： Herman A,de Montjoye L,Tromme I,Goossens A,Baeck M

更新日期：2018-12-01 00:00:00

abstract：:Numerous studies have focused attention on the influence of various biological and environmental factors on contact hypersensitivity. In order to evaluate the persistence and/or modification of allergic contact sensitivity to a number of common contact sensitizers, the same standardized patch tests were repeated on 17...

journal_title：Contact dermatitis

authors： Ayala F,Balato N,Lembo G,Patruno C,Fabbrocini G,Nofroni I,Magliocchetti N,Schena D,Rafanelli A,Seidenari S,Motolese A,Angelini G,Tosti A,Saccabusi S,Pigatto P,Lisi P

更新日期：1996-05-01 00:00:00

abstract：:Kojic acid (5-hydroxy-2-(hydroxymethyl)-4-pyrone), a fungal metabolic product, has increasingly been used as a skin-depigmenting agent in skin care products marketed in Japan since 1988. In order to determine its frequency of sensitization, during 1 year from October 1992 to September 1993, we performed patch testing ...

journal_title：Contact dermatitis

authors： Nakagawa M,Kawai K,Kawai K

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The bark of the cinnamon tree is used as a spice; its flavour is from an essential oil containing mainly cinnamal. OBJECTIVE:To report new cases of occupational allergic contact dermatitis (ACD) from cinnamon and a novel case of airborne cinnamon contact allergy. METHODS:We examined the patient material of...

journal_title：Contact dermatitis

authors： Ackermann L,Aalto-Korte K,Jolanki R,Alanko K

更新日期：2009-02-01 00:00:00

abstract：:Contact allergy to dental allergens is a well-studied subject, more so among dental professionals than dental patients. 1632 subjects had been patch tested to either the dental patient series or dental personnel series at the department of Occupational and Environmental Dermatology, Malmö, Sweden. Positive patch tests...

journal_title：Contact dermatitis

authors： Goon AT,Isaksson M,Zimerson E,Goh CL,Bruze M

更新日期：2006-10-01 00:00:00

abstract：:Allergic contact dermatitis is recognized as a public health problem and some major allergens have been subject to intervention aiming at lowering skin exposure. There is an obvious interest in evaluating the effect of such interventions. Population studies are difficult to perform and epidemiological studies based on...

journal_title：Contact dermatitis

authors： Lindberg M,Edman B,Fischer T,Stenberg B

更新日期：2007-04-01 00:00:00

abstract：:A 59-year-old saleswoman of black hats presented with a severe purpuric eruption of the exposed areas of the face, neck and arms. Patch testing to paraphenylenediamine produced a purpuric test reaction. Similar eruptions have been reported due to N-isopropyl-N-phenylparaphenylenediamine (IPPD), a rubber antioxidant. T...

journal_title：Contact dermatitis

authors： Shimunes E

更新日期：1978-08-01 00:00:00

abstract：:Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...

journal_title：Contact dermatitis

authors： Seukeran DC,Wilkinson SM,Beck MH

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:The prevalence of p-phenylenediamine (PPD) sensitization is 4% in the patch tested population and varies between zero and 1.5% in the general population. Hair dye is a recognised sensitization source. OBJECTIVES:To define the prevalence rates of PPD sensitization in the general and patch tested populations ...

journal_title：Contact dermatitis

authors： Vogel TA,Coenraads PJ,Bijkersma LM,Vermeulen KM,Schuttelaar ML,EDEN Fragrance Study Group.

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Amines in epoxy hardeners are significant causes of occupational allergic contact dermatitis among workers who use epoxy resin systems. OBJECTIVES:To describe a novel group of contact allergens: N-(2-phenylethyl) derivatives of the reactive amine 1,3-benzenedimethanamine (1,3-BDMA). METHODS:We describe the...

journal_title：Contact dermatitis

authors： Pesonen M,Kuuliala O,Suomela S,Aalto-Korte K

更新日期：2016-12-01 00:00:00

abstract：:Surface-active agents (surfactants) are characterized by the possession of 2 different moieties, both polar and non-polar regions on the same molecule. Surfactants are broadly classified as anionic, cationic, amphoteric, or non-ionic, according to the nature of the hydrophile yielded in aqueous solution. In currently ...

journal_title：Contact dermatitis

authors： Effendy I,Maibach HI

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Panthenol (synonym: dexpanthenol), the alcohol analogue of panthothenic acid, is frequently included in moisturizers, wound-healing agents, and other cosmetics, and has been shown to be responsible for allergic contact dermatitis (ACD). OBJECTIVES:To evaluate the frequency of ACD caused by dexpanthenol, and...

journal_title：Contact dermatitis

authors： Fernandes RA,Santiago L,Gouveia M,Gonçalo M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Chromium-tanned leather footwear, which releases >3 ppm hexavalent Cr(VI), may pose a risk of sensitizing and eliciting allergic dermatitis. OBJECTIVES:To determine the content and potential release of chromium in leather footwear and to discuss the prevention of chromium contact allergy and dermatitis. ME...

journal_title：Contact dermatitis

authors： Thyssen JP,Strandesen M,Poulsen PB,Menné T,Johansen JD

更新日期：2012-05-01 00:00:00

abstract：:For more than 50 years, the Draize rabbit skin irritation test has reigned supreme as the regulatory method of choice for the identification of skin irritant chemicals. To date no in vitro alternative test has been validated as an adequate replacement. However, one potential option, to test the endpoint of concern (sk...

journal_title：Contact dermatitis

authors： Robinson MK,McFadden JP,Basketter DA

更新日期：2001-07-01 00:00:00