Abstract:
BACKGROUND:The development of persistent itchy nodules at the injection site following hyposensitization therapy with aluminium-precipitated antigen extract has been described in several reports. Occasionally, contact allergy to aluminium has been reported in individuals with such nodules. OBJECTIVES:To investigate if hyposensitization therapy can induce contact allergy to aluminium and examine if there is any association between persistent subcutaneous nodules and aluminium allergy. PATIENTS/METHODS:Sixty-one children with allergic asthma and/or allergic rhinitis participated in the study of whom 37 had had hyposensitization therapy. The study consisted of a non-clinical part based on a questionnaire and a clinical part with a physical examination, self-assessment of itching, and patch testing. To secure an unbiased evaluation of possible reactions, the investigators were blinded. RESULTS:Contact allergy to aluminium was found in eight participants, all in the exposed group (8/37 versus 0/24, P = 0.02). Examination showed nodules on the upper arms in 13 participants, all in the group exposed to hyposensitization therapy. Nodules were over-represented in patients with contact allergy to aluminium. CONCLUSIONS:There was a statistically significant association between contact allergy to aluminium and persistent subcutaneous nodules in children who had had hyposensitization therapy.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Netterlid E,Hindsén M,Björk J,Ekqvist S,Güner N,Henricson KA,Bruze Mdoi
10.1111/j.1600-0536.2008.01474.xsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
41-9issue
1eissn
0105-1873issn
1600-0536pii
COD1474journal_volume
60pub_type
杂志文章abstract::Erythema caused by occlusion of 3 concentrations of surfactant was quantified in vivo using a modified spectrophotometer. Standard chamber irritation test sites were evaluated objectively using the spectrophotometer and subjectively by trained observers. There was a good relationship between the instrumental and visua...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1988.tb02893.x
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:Contact allergy to epoxy (meth)acrylates, 2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) phenyl]propane (bis-GMA), 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy)phenyl]-propane (bis-GA), 2,2-bis[4-(methacryl-oxyethoxy)phenyl] propane (bis-EMA), 2,2-bis[4-(methacryloxy)phenyl]-propane (bis-MA), and glycidyl methacrylat...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2009.01574.x
更新日期:2009-07-01 00:00:00
abstract::In two cases, occupational contact dermatitis was found to be due to chicory (Cichorium) used as a salad plant. In one of the two cases, contact sensitivity to letuce (Lactuca) was also observed. The sesquiterpene lactones of the plant may be the allergens. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05444.x
更新日期:1975-10-01 00:00:00
abstract::Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly-formulated 'spicy' toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire a...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05330.x
更新日期:1975-01-01 00:00:00
abstract::Some methacrylates are known to be strong contact sensitizers. To determine the effect of side-chain length on sensitizing potential, we examined 11 derivatives with linear side chains from C1 to C18 in an experimental sensitization test in guinea pigs. The results showed an increase in the sensitizing potential with ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1999.tb05971.x
更新日期:1999-01-01 00:00:00
abstract::A pilot study was performed to compare the results obtained by leaving the test substances recommended by ICDRG on the backs of the patients for 24 and 48 h, respectively. The Pirilä chamber test method was used. We got different results between the two methods of application time as reported, and intend to continue t...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1978.tb03851.x
更新日期:1978-12-01 00:00:00
abstract::Risk factors for cement eczema were studied among workers employed in the Danish construction industry. 2 cohorts exposed to cement containing different concentrations of water-soluble chromate were examined. A statistically significant decrease in the number of workers with allergic cement eczema was found in the coh...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1991.tb01793.x
更新日期:1991-08-01 00:00:00
abstract::In this study, 333 nurses, 92 dentists and 167 doctors were investigated. Most positive patch tests obtained were unrelated to occupation. Nurses were most often sensitized to penicillins and, of the disinfectants, formaldehyde was the commonest cause of occupational dermatitis. Among dentists, the most common occupat...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03140.x
更新日期:1989-04-01 00:00:00
abstract::The epidermal response to 2 different irritants, nonanoic acid (NAA) and sodium lauryl sulfate (SLS), was investigated with 2 different methods. NAA 80% and SLS 4% were applied under occlusion for up to 24 h. Elemental changes were determined in cryosections by x-ray microanalysis. Compared to unexposed skin a signifi...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02416.x
更新日期:1996-12-01 00:00:00
abstract::The frequencies of cosmetics intolerance and contact allergy to colophony were investigated among 116 singers and dancers and 16 make-up artists. Participants were interviewed, examined and patch tested with a standard series and materials from the opera house. Common skin lesions were found in 1/3 of participants and...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1995.tb00780.x
更新日期:1995-05-01 00:00:00
abstract::The case of a 40-year-old woman with severe edema of the face and neck after the injection of a local dental anesthetic is presented. The reaction is attributed to the presence of sodium metabisulfite, and antioxidant, in the local anesthetic. Both the anesthetic and the sodium metabisulfite gave a delayed positive pa...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03120.x
更新日期:1989-02-01 00:00:00
abstract::A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1979.tb04860.x
更新日期:1979-07-01 00:00:00
abstract::In an evaluation of the safety of new chemicals, of products containing them, or of novel formulations of existing chemicals which may come into contact with the skin, it is important to incorporate an assessment of specially susceptible sub-populations. Such a group is represented by those who are more likely to expe...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1993.tb03534.x
更新日期:1993-10-01 00:00:00
abstract::Kojic acid (5-hydroxy-2-(hydroxymethyl)-4-pyrone), a fungal metabolic product, has increasingly been used as a skin-depigmenting agent in skin care products marketed in Japan since 1988. In order to determine its frequency of sensitization, during 1 year from October 1992 to September 1993, we performed patch testing ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1995.tb00832.x
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Amines in epoxy hardeners are significant causes of occupational allergic contact dermatitis among workers who use epoxy resin systems. OBJECTIVES:To describe a novel group of contact allergens: N-(2-phenylethyl) derivatives of the reactive amine 1,3-benzenedimethanamine (1,3-BDMA). METHODS:We describe the...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12652
更新日期:2016-12-01 00:00:00
abstract::Data suggests that protection from gloves is paradoxically reduced because of effects of occlusion on the skin. The aim of this study was to characterize these effects on physical and functional properties of stratum corneum. Volunteer trials were conducted using patches of polyvinyl chloride (PVC) glove material on t...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1995.tb00542.x
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this cross-sectional study was to collect data on the prevalence of hand eczema and relevant risk factors in geriatric nurses in Germany. METHODS:1375 geriatric nurses from 86 nursing homes were investigated by 41 occupational physicians. RESULTS:Hand eczema was diagnosed in 243 n...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2008.01496.x
更新日期:2009-03-01 00:00:00
abstract::Exotic wood species are used in the manufacture of furniture, musical instruments, tool handles, and other wooden items. Exposure to sawdust of the wood can produce dermatitis on exposed areas in woodworkers. We studied 7 patients, gaitas constructors who used caviuna wood to make their instruments. They developed der...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2007.01095.x
更新日期:2007-05-01 00:00:00
abstract::Murine models for the assessment of the contact sensitizing properties of chemicals rely on mouse ear swelling tests (Mest), which are not sensitive enough to detect weak sensitizers. The aim of the present study was to develop in mice an adjuvant-free Mest appropriate for in vivo detection of any type of sensitizer (...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1994.tb00650.x
更新日期:1994-04-01 00:00:00
abstract:BACKGROUND:Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer, and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES:To report our experience with contact allergy and ACD caused by lavender, and to rai...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13247
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Cobalt release from dental prostheses has been shown to elicit allergic reactions in cobalt-allergic patients. It is therefore important to investigate whether these prostheses are possible sources of sensitization. OBJECTIVES:To assess (i) cobalt release from dental prostheses and (ii) allergic reactions t...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12649
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Reviews on irritant and allergic airborne contact dermatitis have been previously reported in the literature. MATERIALS AND METHODS:Here, we present an update based on recently published airborne-induced skin reactions. For this survey, we screened the journals Contact Dermatitis, Dermatitis, and included r...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/cod.12022
更新日期:2013-04-01 00:00:00
abstract::The aim of our study was to investigate the risk and characteristics of self-reported skin diseases among hydrotherapists. We attempted to contact 400 adults who participated in 1 of 2 training courses. 248 were reached and 190 of them (76.6%) completed the questionnaires. The data were collected by means of a telepho...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2005.00699.x
更新日期:2005-12-01 00:00:00
abstract::The results of patch tests with colophony in the standard series between 1983 and 1987 were analyzed. 5521 patients were tested in the Department of Dermatology, Hamburg, while 354 were tested in other clinics and private practices. Colophony was positive in 2.4% and 11.9%, respectively. Out of 62 patients in the 1st ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03149.x
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:The evidence on the safety of topical preparations containing botanical extracts is limited. OBJECTIVES:To assess (i) the use of botanically derived compounds in a large population, (ii) the incidence of cutaneous side-effects, and (iii) the diagnostic usefulness of patch testing. METHODS:A questionnaire w...
journal_title:Contact dermatitis
pub_type: 杂志文章,多中心研究
doi:10.1111/cod.12124
更新日期:2014-02-01 00:00:00
abstract::Captafol is a common cause of dermatitis amongst workers in the timber industry. In a survey of 14 timber treatment plants 23% of 133 workers exposed to captafol gave a history suggestive of occupationally induced dermatitis. Although allergic dermatitis can occur, irritant dermatitis is far more common. Attention to ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1979.tb04880.x
更新日期:1979-09-01 00:00:00
abstract::The possible interference of neighbouring allergic patch-test reactions is still an open question. In this study, we investigated whether there is a distance-related mutual modification of neighbouring allergic patch-test reactions to nickel sulfate and potassium dichromate. We used a double-blind multicentre study de...
journal_title:Contact dermatitis
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1034/j.1600-0536.2000.043003144.x
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Nickel is the most common cause of contact allergy and an important risk factor for hand eczema. Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel. OBJECTIVES:To develop and evaluate methods for visualization of ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2010.01856.x
更新日期:2011-03-01 00:00:00
abstract::Of 240 patients treated with 1% tromantadine hydrochloride ointment, 20 showed local irritation, of which 12 were due to contact allergy as demonstrated by patch testing. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1976.tb03049.x
更新日期:1976-10-01 00:00:00
abstract::Investigations on light reactions in a patient with vitiligo are presented. The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1983.tb04429.x
更新日期:1983-09-01 00:00:00