The effects of protective occlusive gloves on stratum corneum barrier properties.

Abstract:

:Data suggests that protection from gloves is paradoxically reduced because of effects of occlusion on the skin. The aim of this study was to characterize these effects on physical and functional properties of stratum corneum. Volunteer trials were conducted using patches of polyvinyl chloride (PVC) glove material on the skin. Impairment of barrier function was assessed by measuring transepidermal water loss (TEWL). Hydration and water sorption-desorption was assessed using skin conductance. The major finding was a short-term impairment of barrier function, measured as an increase in TEWL of 1.7 gn-2h-1 (95% C.I. 0.4 to 2.6 gn-2h-1,p < 0.01). Temporary increases in hydration and water sorption were also observed. On this basis, the effects of wearing PVC gloves over 2 days on stratum corneum barrier properties on the dorsum of the hand were studied. TEWL measurements remained elevated by 1.5 gn-2h-1 the day after occlusive glove removal (95% C.I. 0.2 to 2.8 gn-2h-1, p < 0.01), indicating a possible cumulative effect. In conclusion, our studies demonstrate a potential hazard resulting from the repeated use of protective gloves.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Graves CJ,Edwards C,Marks R

doi

10.1111/j.1600-0536.1995.tb00542.x

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

183-7

issue

3

eissn

0105-1873

issn

1600-0536

journal_volume

33

pub_type

杂志文章
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    abstract::We studied 39 patients with erythema-dyschromicum-perstans-like dermatitis seen at Changuinola Hospital in Panama. They were compared with 41 controls. The 2 groups were native field workers of the banana plantations exposed to many pesticides. In 34 patients, there was a positive patch test reaction to 2,4,5,6-1,3-te...

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02360.x

    authors: Penagos H,Jimenez V,Fallas V,O'Malley M,Maibach HI

    更新日期:1996-10-01 00:00:00

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    doi:10.1111/j.1600-0536.1975.tb05305.x

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    更新日期:1975-01-01 00:00:00

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    pub_type: 杂志文章

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    authors: Osawa J,Kitamura K,Ikezawa Z,Nakajima H

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    更新日期:2015-07-01 00:00:00

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    更新日期:2005-12-01 00:00:00

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    doi:10.1111/j.1600-0536.1976.tb02986.x

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    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0536.1992.tb03280.x

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  • Formaldehyde is a significant allergen in women with hand eczema.

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    doi:10.1111/j.1600-0536.1991.tb01874.x

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1996.tb02246.x

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  • Percutaneous absorption of 3 organic solvents in the guinea pig (V). Effect of "accelerants".

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    doi:10.1111/j.1600-0536.1989.tb04748.x

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  • Contact sensitivity to topical antimicrobials. (II). Sensitizing potentials of some topical antimicrobials.

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    journal_title:Contact dermatitis

    pub_type: 杂志文章

    doi:10.1111/j.1600-0536.1989.tb04730.x

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    journal_title:Contact dermatitis

    pub_type: 杂志文章

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  • Contact Allergy to Polyhexamethylene Biguanide (Polyaminopropyl Biguanide).

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    pub_type: 杂志文章

    doi:10.1111/cod.13728

    authors: Sukakul T,Dahlin J,Pontén A,Antelmi A,Bruze M,Hamnerius N,Hauksson I,Isaksson M,Lejding T,Svedman C

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    pub_type: 杂志文章

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  • Topical cyclosporine: effects on allergic contact dermatitis in guinea pigs.

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    pub_type: 杂志文章

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    更新日期:1989-01-01 00:00:00

  • The role of contact allergy to aeroallergens in atopic dermatitis.

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