Hand eczema in nickel-sensitive female twins. Genetic predisposition and environmental factors.

abstract：:Recognizing the growing need for international standardization of photopatch testing techniques, a standard procedure has been used by Scandinavian dermatological clinics since January 1980. The set-up includes a standardized patient examination scheme, including phototest evaluation of the patient's UVA- and UVB-sens...

journal_title：Contact dermatitis

authors： Jansén CT,Wennersten G,Rystedt I,Thune P,Brodthagen H

更新日期：1982-05-01 00:00:00

abstract：:The development of topical drug products requires testing for skin toxicology reactions. A variety of patch test systems are available with which chemicals are applied to skin. The purpose of this study was to determine the skin absorption of paraphenylenediamine (PPDA) from a variety of such systems. [14C]-PPDA (1% p...

journal_title：Contact dermatitis

authors： Kim HO,Wester RC,McMaster JA,Bucks DA,Maibach HI

更新日期：1987-09-01 00:00:00

abstract：:The dose- and time-related effect of sodium lauryl sulfate (SLS) on in vitro percutaneous penetration was studied using 3 radiolabeled tracer compounds with different physicochemical properties: tritiated water, hydrocortisone and nickel. Human cadaver abdominal skin from caucasian women was used as membrane in static...

journal_title：Contact dermatitis

authors： Frankild S,Andersen KE,Nielsen GD

更新日期：1995-06-01 00:00:00

abstract：:Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...

journal_title：Contact dermatitis

authors： Pontén A,Zimerson E,Sörensen O,Bruze M

更新日期：2004-05-01 00:00:00

abstract：:Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's ...

journal_title：Contact dermatitis

authors： Fenner J,Hadi A,Yeh L,Silverberg N

更新日期：2020-05-01 00:00:00

abstract：:Numerous studies have focused attention on the influence of various biological and environmental factors on contact hypersensitivity. In order to evaluate the persistence and/or modification of allergic contact sensitivity to a number of common contact sensitizers, the same standardized patch tests were repeated on 17...

journal_title：Contact dermatitis

authors： Ayala F,Balato N,Lembo G,Patruno C,Fabbrocini G,Nofroni I,Magliocchetti N,Schena D,Rafanelli A,Seidenari S,Motolese A,Angelini G,Tosti A,Saccabusi S,Pigatto P,Lisi P

更新日期：1996-05-01 00:00:00

abstract：:Allergic contact dermatitis affects a worrying proportion of the general population. The mechanisms underlying this chemical-triggered delayed-type hypersensitivity are still not fully understood. In recent years, basic research has shown that the immune system reacts to contact allergens by activation of signalling p...

journal_title：Contact dermatitis

authors： Martin SF

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Contact allergy to cocamidopropyl betaine has been attributed to its impurities dimethylaminopropylamine and cocamidopropyl dimethylamine. OBJECTIVES:To describe patients with positive patch test reactions to cocamidopropyl betaine-related compounds in an occupational dermatology clinic. METHODS:We reviewe...

journal_title：Contact dermatitis

authors： Suuronen K,Pesonen M,Aalto-Korte K

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The prevalence of body piercing and orthodontic treatment has increased during recent decades. Such changes in lifestyle may influence the occurrence of nickel allergy. OBJECTIVES:The aim of this study was to describe the prevalence of nickel allergy in a Swedish youth population. METHODS:In a cross-sectio...

journal_title：Contact dermatitis

authors： Fors R,Persson M,Bergström E,Stenlund H,Stymne B,Stenberg B

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis caused by (meth)acrylates is well known, both in occupational and in non-occupational settings. Contact hypersensitivity to electrocardiogram (ECG) electrodes containing (meth)acrylates is rarely reported. OBJECTIVE:To report the first case of contact dermatitis caused by acrylic...

journal_title：Contact dermatitis

authors： Stingeni L,Cerulli E,Spalletti A,Mazzoli A,Rigano L,Bianchi L,Hansel K

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:There is a lack of prospective studies investigating contact sensitization in patients with chronic leg ulcers. OBJECTIVES:To determine the frequency of contact sensitization in patients with chronic leg ulcers using a special series of patch tests and to determine whether the number of sensitizations was c...

journal_title：Contact dermatitis

authors： Barbaud A,Collet E,Le Coz CJ,Meaume S,Gillois P

更新日期：2009-05-01 00:00:00

abstract：:The usefulness of a trivalent gold salt, gold trichloride (GTC), was evaluated as a marker of contact allergy to gold. Patients patch test-positive or patch test-negative to gold sodium thiosulfate (GSTS), 13 subjects of each, were patch tested with dilution series of GTC and equimolar concentrations of GSTS. In order...

journal_title：Contact dermatitis

authors： Möller H,Ahnlide I,Gruvberger B,Bruze M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Workers exposed to epoxy products are at risk of developing allergic contact dermatitis. OBJECTIVES:To compare workers throughout the German construction industry with and without skin allergy to epoxy resins, hardeners, and/or reactive diluents, and to investigate which determinants are related to the deve...

journal_title：Contact dermatitis

authors： Spee T,Timmerman JG,Rühl R,Kersting K,Heederik DJ,Smit LA

更新日期：2016-05-01 00:00:00

abstract：:In continuation of our preceding studies, we disclose long-term experiments to test more extensively the protective power of the novel 4H Glove. 2 compounds encountered in modern electron microscopy technique, 1-hexadecene (1-HD) and 2-hydroxyethyl acrylate (2-HEA), which elicit allergic and/or toxic reactions in labo...

journal_title：Contact dermatitis

authors： Tobler M,Freiburghaus AU

更新日期：1992-05-01 00:00:00

abstract：:The aim of our study was to investigate the risk and characteristics of self-reported skin diseases among hydrotherapists. We attempted to contact 400 adults who participated in 1 of 2 training courses. 248 were reached and 190 of them (76.6%) completed the questionnaires. The data were collected by means of a telepho...

journal_title：Contact dermatitis

authors： Lazarov A,Nevo K,Pardo A,Froom P

更新日期：2005-12-01 00:00:00

abstract：:There are at least 2 quantitative variables when applying allergens to obtain sensitization: the absolute amount of allergen and the surface concentration. This review analyzes the limited studies on surface concentration and determines surface area threshold levels for the allergens documented in the literature. ...

journal_title：Contact dermatitis

authors： Upadhye MR,Maibach HI

更新日期：1992-11-01 00:00:00

abstract：:This study presents a profile of patients with chronic recalcitrant eczematous disease referred by dermatologists for contact allergy evaluation. Allergic contact dermatitis (ACD) and irritant responses were carefully defined, as was the presence or absence of atopy obtained by history. Of 410 patients studied, 44% ha...

journal_title：Contact dermatitis

authors： Klas PA,Corey G,Storrs FJ,Chan SC,Hanifin JM

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. OBJECTIVES:To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a ...

journal_title：Contact dermatitis

authors： Isaksson M,Inerot A,Lidén C,Matura M,Stenberg B,Möller H,Bruze M

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:On skin contact, nickel accumulates in the stratum corneum, where it is probably bound to proteins and amino acids. One probable contributor is filaggrin, which binds nickel avidly. Filaggrin gene (FLG) null mutations lead to a complete lack of filaggrin production from the affected allele, and have been ass...

journal_title：Contact dermatitis

authors： Ross-Hansen K,Johansen JD,Vølund A,Menné T,Thyssen JP

更新日期：2014-07-01 00:00:00

abstract：:A pilot study was performed to compare the results obtained by leaving the test substances recommended by ICDRG on the backs of the patients for 24 and 48 h, respectively. The Pirilä chamber test method was used. We got different results between the two methods of application time as reported, and intend to continue t...

journal_title：Contact dermatitis

authors： Skog E,Forsbeck M

更新日期：1978-12-01 00:00:00

abstract：:9 common spices were tested epicutaneously in 338 dermatological patients, 118 of whom were allergic to balsam of Peru. Positive reactions to one or more spices were seen in 50 patients all of whom except 2 were allergic to balsam of Peru. The spices giving positive reactions most often were clove, Jamaica pepper and ...

journal_title：Contact dermatitis

authors： Niinimäki A

更新日期：1984-07-01 00:00:00

abstract：:To investigate the mechanisms of non-immunologic contact urticaria (NICU), the effect of 120 mg of terfenadine (H1-antagonist) on contact reactions to methyl nicotinate, diethyl fumarate, benzoic acid, cinnamic acid, cinnamic aldehyde and dimethyl sulfoxide was studied in 20 subjects. Erythema and edema were observed ...

journal_title：Contact dermatitis

authors： Lahti A

更新日期：1987-04-01 00:00:00

abstract：:Chronic irritant contact dermatitis (ICD) is a common skin disease, especially in the workplace, but determining the recovery time of chronic ICD is not easy. To measure the recovery time of chronic ICD, we examined the skin reactivity to a model surfactant, sodium lauryl sulfate (SLS), on previous chronic ICD and nor...

journal_title：Contact dermatitis

authors： Choi JM,Lee JY,Cho BK

更新日期：2000-05-01 00:00:00

abstract：:The purpose of the present study was to compare the frequency of lanolin allergy during two periods and to assess the adequacy of testing with one standard allergen. Among 1230 consecutive patients with eczema who were standard patch tested, 33 (2.7%), 21 females and 12 males, gave a positive reaction to wool alcohols...

journal_title：Contact dermatitis

authors： Mortensen T

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Hand eczema is a disease with large variation in clinical presentation and severity. Scoring systems for quantitative severity assessment exist. However, they are observer-dependent. An objective quantitative tool for scoring of hand eczema would improve categorization of hand eczema. OBJECTIVE:To investiga...

journal_title：Contact dermatitis

authors： Hald M,Thyssen JP,Zachariae C,Røpke MA,Carstensen JM,Schultz N,Johansen JD

更新日期：2019-12-01 00:00:00

abstract：:The local lymph node assay (LLNA) is used for assessing sensitizing potential in hazard identification and risk assessment for regulatory purposes. Sensitizing potency on the basis of the LLNA is categorized into extreme (EC3 value of ≤0.2%), strong (>0.2% to ≤2%), and moderate (>2%). To compare the sensitizing potenc...

journal_title：Contact dermatitis

authors： Lidén C,Yazar K,Johansen JD,Karlberg AT,Uter W,White IR

更新日期：2016-11-01 00:00:00

abstract：:During the last 2 years, we have performed filaggrin genotyping in patients with eczema seen in our hand eczema clinic. We present pictures of healthy and diseased hands from individuals with filaggrin gene (FLG) mutations to describe a clinical entity of hand eczema. We show that xerosis and hyperkeratosis on the dor...

journal_title：Contact dermatitis

authors： Kaae J,Menné T,Carlsen BC,Zachariae C,Thyssen JP

更新日期：2012-09-01 00:00:00

abstract：:In cases of conjunctivitis associated with the use of soft lenses, delayed hypersensitivity to disinfecting components of the used soft lens liquids has to be considered. In 7/15 patients, positive patch test reactions to merthiolate, chlorhexidine or the soaking solutions were observed. The significance of these find...

journal_title：Contact dermatitis

authors： van Ketel WG,Melzer-van Riemsdijk FA

更新日期：1980-08-01 00:00:00

abstract：:Captafol is a common cause of dermatitis amongst workers in the timber industry. In a survey of 14 timber treatment plants 23% of 133 workers exposed to captafol gave a history suggestive of occupationally induced dermatitis. Although allergic dermatitis can occur, irritant dermatitis is far more common. Attention to ...

journal_title：Contact dermatitis

authors： Stoke JC

更新日期：1979-09-01 00:00:00

abstract：:Our aim was to quantify and qualify the use of complementary medicine (CM) by patients referred to our contact dermatitis clinic in Leicester, UK. A face-to-face structured questionnaire study was made of 109 consecutive patients referred to the contact dermatitis clinic. 109 such questionnaires were completed. 21/109...

journal_title：Contact dermatitis

authors： Nicolaou N,Johnston GA

更新日期：2004-07-01 00:00:00