Contact allergy in chronic leg ulcers: results of a multicentre study carried out in 423 patients and proposal for an updated series of patch tests.

abstract：:The epidermal response to 2 different irritants, nonanoic acid (NAA) and sodium lauryl sulfate (SLS), was investigated with 2 different methods. NAA 80% and SLS 4% were applied under occlusion for up to 24 h. Elemental changes were determined in cryosections by x-ray microanalysis. Compared to unexposed skin a signifi...

journal_title：Contact dermatitis

authors： Grängsjö A,Leijon-Kuligowski A,Törmä H,Roomans GM,Lindberg M

更新日期：1996-12-01 00:00:00

abstract：:During the last 2 years, we have performed filaggrin genotyping in patients with eczema seen in our hand eczema clinic. We present pictures of healthy and diseased hands from individuals with filaggrin gene (FLG) mutations to describe a clinical entity of hand eczema. We show that xerosis and hyperkeratosis on the dor...

journal_title：Contact dermatitis

authors： Kaae J,Menné T,Carlsen BC,Zachariae C,Thyssen JP

更新日期：2012-09-01 00:00:00

abstract：:Patch testing was carried out in 851 atopic patients; 181 atopic dermatitis (AD) patients were additionally tested with 50% dilutions of the test substances. The occurrence of allergic and irritant reactions was frequent, being 57% and 33% for AD patients aged 28-41 years and 19-27 years, respectively. Among age-match...

journal_title：Contact dermatitis

authors： Lammintausta K,Kalimo K,Fagerlund VL

更新日期：1992-04-01 00:00:00

abstract：:Thiourea compounds are mainly used as accelerators in the rubber industry, but also in other industries, e.g., as antioxidants in the graphics industry. Thiourea compounds may provoke allergic contact dermatitis, although the number of reported cases is relatively low. During 1985-1991, we had 5 patients with allergic...

journal_title：Contact dermatitis

authors： Kanerva L,Estlander T,Jolanki R

更新日期：1994-10-01 00:00:00

abstract：:Patch testing is an invaluable tool for the experimental induction of acute irritant contact dermatitis (ICD), with a variety of chamber systems available for use. Ideally, the inflammatory reactions produced should be of uniform intensity across the test area, thereby facilitating grading of the response and tissue s...

journal_title：Contact dermatitis

authors： Nicholson M,Willis CM

更新日期：1999-11-01 00:00:00

abstract：:The aim of our study was to investigate the risk and characteristics of self-reported skin diseases among hydrotherapists. We attempted to contact 400 adults who participated in 1 of 2 training courses. 248 were reached and 190 of them (76.6%) completed the questionnaires. The data were collected by means of a telepho...

journal_title：Contact dermatitis

authors： Lazarov A,Nevo K,Pardo A,Froom P

更新日期：2005-12-01 00:00:00

abstract：:The aim of this study was to elucidate the role of the C11-OH substituent of the corticosteroid molecule in relation to contact allergy to corticosteroids. This group, which is essential for glucocorticoid activity, is not present in other steroid molecules, such as deoxycortisol, progestagens, testosterone, and estro...

journal_title：Contact dermatitis

authors： Schoenmakers A,Vermorken A,Degreef H,Dooms-Goossens A

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:The preservative methyldibromo glutaronitrile (MDBGN) has been banned, first from stay-on, and later from rinse-off cosmetics, in the EU countries because of increasing rates of contact allergy. OBJECTIVES:To evaluate the frequency of contact allergy to MDBGN among patients patch tested by the Danish Contac...

journal_title：Contact dermatitis

authors： Johansen JD,Veien N,Laurberg G,Avnstorp C,Kaaber K,Andersen KE,Paulsen E,Sommerlund M,Thormann J,Nielsen NH,Vissing S,Kristensen O,Kristensen B,Agner T,Menné T

更新日期：2008-07-01 00:00:00

abstract：:Predictive guinea pig sensitization studies have been performed with commercial and purified 1H-benzotriazole. In only 3 animals, induced and challenged according to the maximization protocol with more than 100 times the normal use concentration, were slight erythemas elicited with the commercial grade of benzotriazol...

journal_title：Contact dermatitis

authors： Maurer T,Meier F

更新日期：1984-03-01 00:00:00

abstract：:Many factors can influence the elicitation of hypersensitivity reactions in guinea pigs and humans. The effect which the vehicle might have on the test response in guinea pigs sensitized with various acrylic compounds, using the "guinea pig maximization test", has been investigated. A marked decrease in the number of ...

journal_title：Contact dermatitis

authors： Björkner B,Niklasson B

更新日期：1984-11-01 00:00:00

abstract：:To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...

journal_title：Contact dermatitis

authors： Thyssen JP,Giménez-Arnau E,Lepoittevin JP,Menné T,Boman A,Schnuch A

更新日期：2012-04-01 00:00:00

abstract：:Allergic contact dermatitis affects a worrying proportion of the general population. The mechanisms underlying this chemical-triggered delayed-type hypersensitivity are still not fully understood. In recent years, basic research has shown that the immune system reacts to contact allergens by activation of signalling p...

journal_title：Contact dermatitis

authors： Martin SF

更新日期：2015-01-01 00:00:00

abstract：:Sesquiterpene lactones (STL) of the sunflower, occurring in fragile multicellular capitate glandular hairs, have been shown to display a remarkable sensitizing capacity when investigated by experimental sensitization in guinea pigs. The strongest response was induced by the hemiketal form of 1-O-methyl-4,5-dihydronive...

journal_title：Contact dermatitis

authors： Hausen BM,Spring O

更新日期：1989-05-01 00:00:00

abstract：:Diglycidyl ether of bisphenol A (DGEBA) is the monomer and most important contact allergen in epoxy resin(s) based on bisphenol A (DGEBA-R). Both thin-layer chromatography (TLC) and high-pressure liquid chromatography (HPLC) methods are available for the analysis of products containing DGEBA-R. With respect to detecti...

journal_title：Contact dermatitis

authors： Pontén A,Zimerson E,Sörensen O,Bruze M

更新日期：2004-05-01 00:00:00

abstract：:Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...

journal_title：Contact dermatitis

authors： Levin CY,Maibach HI

更新日期：2001-09-01 00:00:00

abstract：:We compared the incidence of occupational dermatitis and transepidermal water vapour loss (TEWL) changes from cutting fluids (neat mineral oils) in 24 new machinists with 27 armed forces paramedics (controls) over a 6-month period. The cumulative incidence of occupational dermatitis in positive controls increased from...

journal_title：Contact dermatitis

authors： Goh CL,Gan SL

更新日期：1994-08-01 00:00:00

abstract：:Piroxicam (PXM) is a nonsteroidal anti-inflammatory drug which may induce a photosensitive eruption shortly after administration. We examined whether animals sensitized to thimerosal developed a photosensitivity to PXM. Male Hartley strain guinea pigs were sensitized to thimerosal, thiosalicylate and PXM separately. T...

journal_title：Contact dermatitis

authors： Kitamura K,Osawa J,Ikezawa Z,Nakajima H

更新日期：1991-07-01 00:00:00

abstract：:"Eau de Javel" (liquid bleach) is a common cause of chromate contact allergy. A historical review explains the reasons for the addition of sodium dichromate after the First World War. The chromium content in different brands of eau de Javel has been determined by flameless atomic absorption spectrophotometry. The resu...

journal_title：Contact dermatitis

authors： Lachapelle JM,Lauwerys R,Tennstedt D,Andanson J,Benezra C,Chabeau G,Ducombs G,Foussereau J,Lacroix M,Martin P

更新日期：1980-01-01 00:00:00

abstract：:A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...

journal_title：Contact dermatitis

authors： Mathias CG,Maibach HI

更新日期：1979-07-01 00:00:00

abstract：:Serious adverse skin reactions to permanent hair dyes and temporary black tattoos have been reported. As temporary tattoos have become fashionable among adolescents, the risk profile for p-phenylenediamine (PPD) sensitization of the population has changed simultaneously with an increasing use of hair dyes in this age ...

journal_title：Contact dermatitis

authors： Sosted H,Johansen JD,Andersen KE,Menné T

更新日期：2006-02-01 00:00:00

abstract：:The possible interference of neighbouring allergic patch-test reactions is still an open question. In this study, we investigated whether there is a distance-related mutual modification of neighbouring allergic patch-test reactions to nickel sulfate and potassium dichromate. We used a double-blind multicentre study de...

journal_title：Contact dermatitis

authors： Brasch J,Kreilgård B,Henseler T,Aberer W,Fuchs T,Pflüger R,Hoeck U,Gefeller O

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Reviews on irritant and allergic airborne contact dermatitis have been previously reported in the literature. MATERIALS AND METHODS:Here, we present an update based on recently published airborne-induced skin reactions. For this survey, we screened the journals Contact Dermatitis, Dermatitis, and included r...

journal_title：Contact dermatitis

authors： Swinnen I,Goossens A

更新日期：2013-04-01 00:00:00

abstract：:There are at least 2 quantitative variables when applying allergens to obtain sensitization: the absolute amount of allergen and the surface concentration. This review analyzes the limited studies on surface concentration and determines surface area threshold levels for the allergens documented in the literature. ...

journal_title：Contact dermatitis

authors： Upadhye MR,Maibach HI

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Exposure to humid environments/water and prolonged glove occlusion are both believed to cause irritant contact dermatitis. OBJECTIVES:To study the effects of different forms of wet work, especially the differences between water exposure and occlusion, by using an experimental model simulating occupational w...

journal_title：Contact dermatitis

authors： Fartasch M,Taeger D,Broding HC,Schöneweis S,Gellert B,Pohrt U,Brüning T

更新日期：2012-10-01 00:00:00

abstract：:Serum from guinea pigs exposed to a single high dose of UVB and from controls was injected into the spleen of normal animals 5 days prior to sensitization. When 1.0 ml was transferred 4.5 h after irradiation, immunosuppression was obtained. Transfer of 1.5 ml of serum 2.5 h after irradiation failed to induce immunosup...

journal_title：Contact dermatitis

authors： Christensen OB,Christensen MB,Wall LM

更新日期：1987-04-01 00:00:00

abstract：:Although hand hygiene is an important and inexpensive measure to prevent nosocomial infections in clinical settings, the compliance of healthcare workers remains low. In Europe, alcoholic hand disinfection is first choice, but there exists a limited user acceptability due to estimated adverse effects on skin condition...

journal_title：Contact dermatitis

authors： Houben E,De Paepe K,Rogiers V

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. OBJECTIVES:To study patterns of simultaneous patch test reactions to thiurams and dithiocarbamates at the Finnish Institute of Occupational Health in 1991-2015. METHODS:We searched the patch test files for patients with...

journal_title：Contact dermatitis

authors： Aalto-Korte K,Pesonen M

更新日期：2016-12-01 00:00:00

abstract：:According to some reports in the literature, the hormonal fluctuations which occur during the menstrual cycle may affect the clinical expression of contact allergy to a greater or lesser degree. In clinical practice, too, patient history often shows exacerbation of the contact dermatitis during the days immediately pr...

journal_title：Contact dermatitis

authors： Bonamonte D,Foti C,Antelmi AR,Biscozzi AM,Naro ED,Fanelli M,Loverro G,Angelini G

更新日期：2005-06-01 00:00:00

abstract：:Patch testing, using European standard allergens and suspected causative substances brought in by patients, was carried out in 490 patients with eczema in Hong Kong and 437 completed the test. Before patch testing, 244, 141 and 105 patients were diagnosed as having contact dermatitis, endogenous eczema and unclassifie...

journal_title：Contact dermatitis

authors： Lee TY,Lam TH

更新日期：1996-07-01 00:00:00

abstract：:1310 patients were routinely patch tested with a paratertiary-butylphenol-formaldehyde resin (PTBP-F-R), a resol resin based on phenol and formaldehyde (P-F-R-2), and a mixture of these 2 resins. Approximately 2.5 times more patients with contact allergy to phenol-formaldehyde resins were diagnosed when routinely patc...

journal_title：Contact dermatitis

authors： Bruze M

更新日期：1988-08-01 00:00:00