Influence of area of application of allergen on sensitization in contact dermatitis.

abstract：:Common emulsifiers were tested in over 1,200 patients with eczema. Triethanolamine stearate tested at 5% in petrolatum caused irritant reactions in 9.5% of the patients. On the other hand, non-ionic emulsifying agents tested at 10-20% produced irritation in only a few cases. Allergic reactions were found in 2.1% of th...

journal_title：Contact dermatitis

authors： Hannuksela M,Kousa M,Pirilä V

更新日期：1976-08-01 00:00:00

abstract：:A maximization test (after Magnusson & Kligman 1970), a single injection adjuvant test (SIAT) and a modified Draize test procedure for assessing contact sensitization potential in guinea-pigs have been compared for their ability to detect 19 known human contact sensitizers. The results show that the modified Draize pr...

journal_title：Contact dermatitis

authors： Goodwin BF,Crevel RW,Johnson AW

更新日期：1981-09-01 00:00:00

abstract：:Skin protection measures - barrier creams, protective gloves - and skin care are widely recommended for the prevention of occupational hand dermatitis (HD) in skin risk professions, but there is hardly anything known about uptake levels of the measures. The objective of this controlled intervention study was to quanti...

journal_title：Contact dermatitis

authors： Bauer A,Kelterer D,Bartsch R,Pearson J,Stadeler M,Kleesz P,Elsner P,Williams H

更新日期：2002-02-01 00:00:00

abstract：:As part of the investigation of sources of exposure to rosin allergens, disposable diapers (napkins) common on the Swedish market were analyzed, using gas chromatography, to detect the main rosin compounds. Rosin components were detected in all diapers, the highest amounts in those from the 2 major producers. In these...

journal_title：Contact dermatitis

authors： Karlberg AT,Magnusson K

更新日期：1996-03-01 00:00:00

abstract：:In four patients suffering from allergic contact eczema, the risk of sensitization to a new residue-leaving fungicide (Plondrel) used in spraying roses is considered. Two patients, however, were probably also sensitized to materials from the roses themselves. By gas-liquid chromatography the amount of the fungicide, e...

journal_title：Contact dermatitis

authors： van Ketel WG

更新日期：1975-10-01 00:00:00

abstract：:Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to chromium from leather products includes both Cr(III) and Cr(VI). We have determined and compared the minimum elicitation threshold (MET) concentration for Cr(III) and Cr(VI) in Cr(VI)-sensitive patients. In addition,...

journal_title：Contact dermatitis

authors： Hansen MB,Johansen JD,Menné T

更新日期：2003-10-01 00:00:00

abstract：:Vulvar tissue is more permeable than exposed skin due to differences in structure, occlusion, hydration and susceptibility to friction. The safety assessment of products that contact the vulva should account for this potentially heightened permeability. Standard clinical patch tests may not sufficiently mimic vulvar e...

journal_title：Contact dermatitis

authors： Farage M,Maibach HI

更新日期：2004-10-01 00:00:00

abstract：:Adverse cutaneous reactions to topically applied olive oil are seldom reported, and positive patch tests to it are mostly regarded as allergic. To evaluate such "positive" patch test reactions, 77 female (mean age: 44 years) and 23 male eczema patients (mean age: 46 years) were prospectively patch tested with freshly ...

journal_title：Contact dermatitis

authors： Kränke B,Komericki P,Aberer W

更新日期：1997-01-01 00:00:00

abstract：:The aim of the study is to describe the ability of patients with allergic contact dermatitis to avoid exposure to allergens in cosmetics. The study is a questionnaire survey among 382 patients with contact allergy to preservatives and fragrances, included from 3 dermatological clinics. The questionnaire included quest...

journal_title：Contact dermatitis

authors： Noiesen E,Munk MD,Larsen K,Johansen JD,Agner T

更新日期：2007-08-01 00:00:00

abstract：:Captafol is a common cause of dermatitis amongst workers in the timber industry. In a survey of 14 timber treatment plants 23% of 133 workers exposed to captafol gave a history suggestive of occupationally induced dermatitis. Although allergic dermatitis can occur, irritant dermatitis is far more common. Attention to ...

journal_title：Contact dermatitis

authors： Stoke JC

更新日期：1979-09-01 00:00:00

abstract：:Between January 1993 and February 2002, 40 of 1354 (3%) workers who attended a tertiary referral occupational dermatology clinic were diagnosed with allergic contact dermatitis (ACD) from epoxy resin systems (ER). 20 of these patients were followed up at least 2 years post-diagnosis to establish prognosis. Characteris...

journal_title：Contact dermatitis

authors： Cahill J,Keegel T,Dharmage S,Nugriaty D,Nixon R

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Cosensitization to nickel, cobalt and chromium occurs in the general population and in some occupational groups. OBJECTIVES:To estimate the isolated and concurrent occurrence of nickel, cobalt and chromium contact sensitization and their association with individual and occupational risk factors. PATIENTS/M...

journal_title：Contact dermatitis

authors： Rui F,Bovenzi M,Prodi A,Fortina AB,Romano I,Corradin MT,Filon FL

更新日期：2012-12-01 00:00:00

abstract：:We report the results of scarified photopatch testing in 3 patients with photosensitivity to lomefloxacin, a new quinolone antibacterial agent introduced onto the Japanese market in April 1990. The patients developed pruritic eczematous lesions on sun-exposed areas 5 days to 3 weeks after they had started taking lomef...

journal_title：Contact dermatitis

authors： Kurumaji Y,Shono M

更新日期：1992-01-01 00:00:00

abstract：:Despite the frequency of irritant contact dermatitis, very little is known about the duration of barrier function impairment following cumulative irritant contact dermatitis. We studied post-irritation irritant reactivity by assessing the response to SLS irritation in previously irritated sites. Cumulative irritant co...

journal_title：Contact dermatitis

authors： Widmer J,Elsner P,Burg G

更新日期：1994-01-01 00:00:00

abstract：:Protein kinase C (PKC) isoforms are important in cell signal transduction associated with regulation of cell proliferation and differentiation. In this study, alterations of PKC isoform levels in irritant patch test reactions were detected by Western immunoblots. 4 chemically and structurally different irritants, 4% a...

journal_title：Contact dermatitis

authors： Li LF,Fiedler VC,Kumar R

更新日期：1998-06-01 00:00:00

abstract：:Machinists and machine maintenance men working in the metal industry use metal-working fluids capable of causing irritant and allergic contact dermatitis. The objectives of this study were to find out the frequency of skin symptoms in machinists and machine maintenance men (metal workers) and to compare the risk of th...

journal_title：Contact dermatitis

authors： Suuronen K,Jolanki R,Luukkonen R,Alanko K,Susitaival P

更新日期：2007-10-01 00:00:00

abstract：:Three cases of contact allergy to Kathon CG, a preservative for cosmetics and toiletries containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one are presented. In two patients, Kathon CG was contained in a moisturizing cream, and the third was sensitized by a diagnos...

journal_title：Contact dermatitis

authors： de Groot AC,Liem DH,Weyland JW

更新日期：1985-02-01 00:00:00

abstract：:Cheilitis granulomatosa (CG) is a rare disorder of unknown origin, which is characterized clinically by painless, recurrent or persistent swelling of 1 or both lips. Betel quids, composed of betel nuts (seeds of the Areca catechu), slake lime, and Piper betel leaf/or Piper betel inflorescence, are widely used in Asia ...

journal_title：Contact dermatitis

authors： Chiu CS,Tsai YL

更新日期：2008-04-01 00:00:00

abstract：:In 1988, 64% of our patients patch test positive to at least 1 allergen of the ICDRG standard series were nickel sensitive. In 70% of 300 patients evaluated, dermatitis started on the earlobes and was related to the regular wearing of cheap earrings. At the same time, 62% of 735 young schoolgirls were found to have de...

journal_title：Contact dermatitis

authors： Santucci B,Ferrari PV,Cristaudo A,Cannistraci C,Picardo M

更新日期：1989-10-01 00:00:00

abstract：:Piroxicam (PXM) is a nonsteroidal anti-inflammatory drug which may induce a photosensitive eruption shortly after administration. We examined whether animals sensitized to thimerosal developed a photosensitivity to PXM. Male Hartley strain guinea pigs were sensitized to thimerosal, thiosalicylate and PXM separately. T...

journal_title：Contact dermatitis

authors： Kitamura K,Osawa J,Ikezawa Z,Nakajima H

更新日期：1991-07-01 00:00:00

abstract：:Patch testing with chemical irritants almost always produces a striking variability in the intensity of reaction between individuals, even amongst normal, healthy subjects. Whilst there have been many attempts to define factors which predispose to heightened or, conversely, to diminished reactivity, the underlying cel...

journal_title：Contact dermatitis

authors： Willis CM

更新日期：2002-11-01 00:00:00

abstract：:Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...

journal_title：Contact dermatitis

authors： Seukeran DC,Wilkinson SM,Beck MH

更新日期：1997-03-01 00:00:00

abstract：:A 24-year-old female working in the Department of Pathology of a University Hospital developed an acute peri-ocular eczema clearly being related to her daily work at the microscope. Patch testing revealed delayed type hypersensitivity against the black rubber mix, N-isopropyl-N'-phenyl paraphenylenediamine, N-cyclohex...

journal_title：Contact dermatitis

authors： Kuijpers DI,Hillen F,Frank JA

更新日期：2006-08-01 00:00:00

abstract：:Chronic irritant contact dermatitis (ICD) is one of the most pressing problems in occupational medicine and is common in the food processing industry. To date, protective creams that fulfil the special requirements in the foodstuffs industry have not been available. Therefore, we studied the efficacy of pre-exposure a...

journal_title：Contact dermatitis

authors： Schliemann-Willers S,Wigger-Alberti W,Kleesz P,Grieshaber R,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to elucidate the role of the C11-OH substituent of the corticosteroid molecule in relation to contact allergy to corticosteroids. This group, which is essential for glucocorticoid activity, is not present in other steroid molecules, such as deoxycortisol, progestagens, testosterone, and estro...

journal_title：Contact dermatitis

authors： Schoenmakers A,Vermorken A,Degreef H,Dooms-Goossens A

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Exposure to humid environments/water and prolonged glove occlusion are both believed to cause irritant contact dermatitis. OBJECTIVES:To study the effects of different forms of wet work, especially the differences between water exposure and occlusion, by using an experimental model simulating occupational w...

journal_title：Contact dermatitis

authors： Fartasch M,Taeger D,Broding HC,Schöneweis S,Gellert B,Pohrt U,Brüning T

更新日期：2012-10-01 00:00:00

abstract：:16 children with atopic dermatitis and 4 nonatopics were skin tested with flavourings and perfumes. Immediate reactions to balsam of Peru and fragrance-mix were found in 9 atopics, and none among nonatopics. An irritant is more probable than an immunologic mechanism. Allergen solutions should probably be assayed at a ...

journal_title：Contact dermatitis

authors： Abifadel R,Mortureux P,Perromat M,Ducombs G,Taieb A

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Nickel is the most common cause of contact allergy and an important risk factor for hand eczema. Visualization techniques may be powerful in showing exposures. The dimethylglyoxime (DMG) test might be used to establish skin exposure to nickel. OBJECTIVES:To develop and evaluate methods for visualization of ...

journal_title：Contact dermatitis

authors： Julander A,Skare L,Vahter M,Lidén C

更新日期：2011-03-01 00:00:00

abstract：:A pilot study was performed to compare the results obtained by leaving the test substances recommended by ICDRG on the backs of the patients for 24 and 48 h, respectively. The Pirilä chamber test method was used. We got different results between the two methods of application time as reported, and intend to continue t...

journal_title：Contact dermatitis

authors： Skog E,Forsbeck M

更新日期：1978-12-01 00:00:00

abstract：:Surface-active agents (surfactants) are characterized by the possession of 2 different moieties, both polar and non-polar regions on the same molecule. Surfactants are broadly classified as anionic, cationic, amphoteric, or non-ionic, according to the nature of the hydrophile yielded in aqueous solution. In currently ...

journal_title：Contact dermatitis

authors： Effendy I,Maibach HI

更新日期：1995-10-01 00:00:00