Down-regulation of protein kinase C isoforms in irritant contact dermatitis.

abstract：:In an evaluation of the safety of new chemicals, of products containing them, or of novel formulations of existing chemicals which may come into contact with the skin, it is important to incorporate an assessment of specially susceptible sub-populations. Such a group is represented by those who are more likely to expe...

journal_title：Contact dermatitis

authors： Basketter DA,Griffiths HA

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Several studies have assessed the effect of patient education regarding hand eczema (HE) severity and quality of life. Few studies, however, have evaluated patients' knowledge. OBJECTIVES:To examine knowledge of skin protection in HE patients following a guided talk, and to identify variables associated wit...

journal_title：Contact dermatitis

authors： Topal Y,Agner T,van der Heiden J,Ebbehøj NE,Clemmensen KKB

更新日期：2019-08-01 00:00:00

abstract：:A sugar refinery worker developed allergic contact dermatitis of his feet secondary to rubber accelerators in his work boots. The dermatitis resolved when polyvinyl chloride work boots were substituted. The importance of controlling hyperhidrosis in the management of foot dermatitis in workers is discussed. ...

journal_title：Contact dermatitis

authors： Mathias CG,Maibach HI

更新日期：1979-07-01 00:00:00

abstract：:The development of hand eczema was evaluated in an 8-year follow-up study carried out in 51 junior hairdressers. Predisposing factors were investigated. Data were collected by use of a self-administered questionnaire: 74% response. None of the junior hairdressers presented with hand eczema at the start of the survey. ...

journal_title：Contact dermatitis

authors： Majoie IM,von Blomberg BM,Bruynzeel DP

更新日期：1996-04-01 00:00:00

abstract：:Colour developers are widely used and contact dermatitis and lichen planus-like eruptions from them are well-known. As a result of automation, there have been few recent reports of contact dermatitis from colour developers. We describe here 4 cases of dermatoses from Kodak CD4 colour developer and study their cross se...

journal_title：Contact dermatitis

authors： Goh CL,Kwok SF,Rajan VS

更新日期：1984-05-01 00:00:00

abstract：:In continuation of our preceding studies, we disclose long-term experiments to test more extensively the protective power of the novel 4H Glove. 2 compounds encountered in modern electron microscopy technique, 1-hexadecene (1-HD) and 2-hydroxyethyl acrylate (2-HEA), which elicit allergic and/or toxic reactions in labo...

journal_title：Contact dermatitis

authors： Tobler M,Freiburghaus AU

更新日期：1992-05-01 00:00:00

abstract：:Cyclosporine (CSA) is an effective immunosuppressive agent and is used in tissue transplantation. The present investigation was undertaken to determine the effect of topical delivery of CSA on allergic contact dermatitis in guinea pigs. Topical 15% CSA in an azone (1-dodecylazacycloheptan-2-one)-containing vehicle blo...

journal_title：Contact dermatitis

authors： Biren CA,Barr RJ,Ganderup GS,Lemus LL,McCullough JL

更新日期：1989-01-01 00:00:00

abstract：:3 patients with contact dermatitis to an ethyl cyanoacrylate glue are presented. Although reactions to cyanoacrylate glues are considered rare, more widespread use of these products by nail salons is likely to be associated with an increased incidence of positive reactions. All 3 of our patients came into contact with...

journal_title：Contact dermatitis

authors： Belsito DV

更新日期：1987-10-01 00:00:00

abstract：:A case of subacute parathion poisoning with an erysipeloid-like eruption of the left index finger is reported. Laboratory investigations showed no growth of pathogenic bacteria and cholinesterase activity in the blood showed a rise 10 days after the poisoning. Further blood investigations 6 weeks later showed subnorma...

journal_title：Contact dermatitis

authors： Svindland HB

更新日期：1981-07-01 00:00:00

abstract：:Deodorants are one of the most marketed types of cosmetics and are frequently reported as a cause of dermatitis, particularly among fragrance-sensitive persons. The aim of this study was to investigate the ability of deodorants, which had previously caused axillary dermatitis in fragrance-mix-sensitive eczema patients...

journal_title：Contact dermatitis

authors： Johansen JD,Rastogi SC,Bruze M,Andersen KE,Frosch P,Dreier B,Lepoittevin JP,White I,Menné T

更新日期：1998-10-01 00:00:00

abstract：:Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...

journal_title：Contact dermatitis

authors： Levin CY,Maibach HI

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Contact allergy is frequent among persons with hand eczema and may be associated with a poor prognosis. OBJECTIVES:To identify allergens associated with the most severe initial clinical symptoms and the worst prognosis in a cohort of hand eczema patients followed for 6 months. METHODS:The study population ...

journal_title：Contact dermatitis

authors： Hald M,Agner T,Blands J,Ravn H,Johansen JD

更新日期：2009-08-01 00:00:00

abstract：:Numerous studies have focused attention on the influence of various biological and environmental factors on contact hypersensitivity. In order to evaluate the persistence and/or modification of allergic contact sensitivity to a number of common contact sensitizers, the same standardized patch tests were repeated on 17...

journal_title：Contact dermatitis

authors： Ayala F,Balato N,Lembo G,Patruno C,Fabbrocini G,Nofroni I,Magliocchetti N,Schena D,Rafanelli A,Seidenari S,Motolese A,Angelini G,Tosti A,Saccabusi S,Pigatto P,Lisi P

更新日期：1996-05-01 00:00:00

abstract：:Murine models for the assessment of the contact sensitizing properties of chemicals rely on mouse ear swelling tests (Mest), which are not sensitive enough to detect weak sensitizers. The aim of the present study was to develop in mice an adjuvant-free Mest appropriate for in vivo detection of any type of sensitizer (...

journal_title：Contact dermatitis

authors： Garrigue JL,Nicolas JF,Fraginals R,Benezra C,Bour H,Schmitt D

更新日期：1994-04-01 00:00:00

abstract：:Musk ambrette has become one of the commonest photosensitizers in many countries and is the cause of persistent light reactions in many patients. A simple method is presented for qualitative analysis for musk ambrette and other nitromusks in colognes using thin-layer chromatography with toluene as carrier solvent and ...

journal_title：Contact dermatitis

authors： Goh CL,Kwok SF

更新日期：1986-01-01 00:00:00

abstract：:A maximization test (after Magnusson & Kligman 1970), a single injection adjuvant test (SIAT) and a modified Draize test procedure for assessing contact sensitization potential in guinea-pigs have been compared for their ability to detect 19 known human contact sensitizers. The results show that the modified Draize pr...

journal_title：Contact dermatitis

authors： Goodwin BF,Crevel RW,Johnson AW

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:The prognosis of occupational hand eczema is strongly associated with its duration, severity, and the onset of treatment. OBJECTIVES:The study was aimed at characterizing skin eruptions that might be potential precursors of occupational hand eczema, their pattern, and typical sites in a population at modera...

journal_title：Contact dermatitis

authors： Baumeister T,Uter W,Weistenhöfer W,Drexler H,Kütting B

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Cyclic acid anhydrides often cause allergic respiratory diseases, but contact urticaria because of these anhydrides has been considered rare. OBJECTIVE:We describe 21 patients diagnosed with occupational contact urticaria at the Finnish Institute of Occupational Health during the period 1990-2006. METHOD:P...

journal_title：Contact dermatitis

authors： Helaskoski E,Kuuliala O,Aalto-Korte K

更新日期：2009-04-01 00:00:00

abstract：:During the last 2 years, we have performed filaggrin genotyping in patients with eczema seen in our hand eczema clinic. We present pictures of healthy and diseased hands from individuals with filaggrin gene (FLG) mutations to describe a clinical entity of hand eczema. We show that xerosis and hyperkeratosis on the dor...

journal_title：Contact dermatitis

authors： Kaae J,Menné T,Carlsen BC,Zachariae C,Thyssen JP

更新日期：2012-09-01 00:00:00

abstract：:The dose- and time-related effect of sodium lauryl sulfate (SLS) on in vitro percutaneous penetration was studied using 3 radiolabeled tracer compounds with different physicochemical properties: tritiated water, hydrocortisone and nickel. Human cadaver abdominal skin from caucasian women was used as membrane in static...

journal_title：Contact dermatitis

authors： Frankild S,Andersen KE,Nielsen GD

更新日期：1995-06-01 00:00:00

abstract：:Investigations on light reactions in a patient with vitiligo are presented. The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins...

journal_title：Contact dermatitis

authors： Kavli G,Midelfart K,Raa J,Volden G

更新日期：1983-09-01 00:00:00

abstract：:Thiourea compounds are mainly used as accelerators in the rubber industry, but also in other industries, e.g., as antioxidants in the graphics industry. Thiourea compounds may provoke allergic contact dermatitis, although the number of reported cases is relatively low. During 1985-1991, we had 5 patients with allergic...

journal_title：Contact dermatitis

authors： Kanerva L,Estlander T,Jolanki R

更新日期：1994-10-01 00:00:00

abstract：:Surface-active agents (surfactants) are characterized by the possession of 2 different moieties, both polar and non-polar regions on the same molecule. Surfactants are broadly classified as anionic, cationic, amphoteric, or non-ionic, according to the nature of the hydrophile yielded in aqueous solution. In currently ...

journal_title：Contact dermatitis

authors： Effendy I,Maibach HI

更新日期：1995-10-01 00:00:00

abstract：:Allergic contact dermatitis is recognized as a public health problem and some major allergens have been subject to intervention aiming at lowering skin exposure. There is an obvious interest in evaluating the effect of such interventions. Population studies are difficult to perform and epidemiological studies based on...

journal_title：Contact dermatitis

authors： Lindberg M,Edman B,Fischer T,Stenberg B

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The preservative methyldibromo glutaronitrile (MDBGN) has been banned, first from stay-on, and later from rinse-off cosmetics, in the EU countries because of increasing rates of contact allergy. OBJECTIVES:To evaluate the frequency of contact allergy to MDBGN among patients patch tested by the Danish Contac...

journal_title：Contact dermatitis

authors： Johansen JD,Veien N,Laurberg G,Avnstorp C,Kaaber K,Andersen KE,Paulsen E,Sommerlund M,Thormann J,Nielsen NH,Vissing S,Kristensen O,Kristensen B,Agner T,Menné T

更新日期：2008-07-01 00:00:00

abstract：:An outbreak of occupational dermatitis in an electroforming plant where there was heavy exposure to nickel is described. Patch test investigations confirmed nickel allergy in 13 of 27 exposed individuals. Nickel chloride was found to be a more reliable patch test allergen than nickel sulphate. Improvements in industri...

journal_title：Contact dermatitis

authors： Wall LM,Calnan CD

更新日期：1980-10-01 00:00:00

abstract：:We review controlled trials of corticosteroid effect in experimentally elicited acute nickel contact dermatitis in man, in the hope of clarifying optimal efficacy for clinical use. To maximize discrimination and objectivity, we focus on data with 1 well-characterized allergen, nickel, in studies utilizing bioengineeri...

journal_title：Contact dermatitis

authors： Levin C,Maibach HI

更新日期：2000-12-01 00:00:00

abstract：:Shiitake (Lentinus edodes) is a mushroom which is eaten in Chinese and Japanese meals and is nowadays the second most commonly produced edible mushroom in the world. Shiitake dermatitis was first described by Nakamura in 1977. This disease presents with very characteristic skin manifestations. From April 1974 to April...

journal_title：Contact dermatitis

authors： Nakamura T

更新日期：1992-08-01 00:00:00

abstract：:Copolymers or heteropolymers are large molecules with high molecular weights (>1000 D). They have been underestimated for a long time as to their sensitizing capacities. Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still u...

journal_title：Contact dermatitis

authors： Quartier S,Garmyn M,Becart S,Goossens A

更新日期：2006-11-01 00:00:00

abstract：:The ingredients previously reported to cause protective glove allergy are presented and evaluated for strength of evidence. Allergens that have caused both delayed hypersensitivity and contact urticaria are considered for rubber, plastic, leather, and textile gloves. The current guidelines regarding glove manufacture ...

journal_title：Contact dermatitis

authors： Rose RF,Lyons P,Horne H,Mark Wilkinson S

更新日期：2009-09-01 00:00:00