Abstract:
:We report the results of scarified photopatch testing in 3 patients with photosensitivity to lomefloxacin, a new quinolone antibacterial agent introduced onto the Japanese market in April 1990. The patients developed pruritic eczematous lesions on sun-exposed areas 5 days to 3 weeks after they had started taking lomefloxacin. 2 cases reacted positively to lomefloxacin on scarified photopatch testing down to 0.1% pet., and 1 patient down to 10% pet. One of them also showed positive reactions on conventional photopatch testing. Scarified photopatch testing with 7 other pyridone carbonate derivatives in 2 of the 3 cases, however, did not show any positive reactions. Patch and scarified patch testing were negative in all patients. The clinical course, clinical and histological findings and results of skin tests in these patients suggest that photoallergic mechanisms are involved. This is the 1st report of positive reactions on scarified photopatch testing, which appears to be a useful method of detecting the causative drug in drug-induced photosensitivity.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Kurumaji Y,Shono Mdoi
10.1111/j.1600-0536.1992.tb00860.xkeywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
5-10issue
1eissn
0105-1873issn
1600-0536journal_volume
26pub_type
杂志文章abstract::The introduction of the euro has revived interest in the risk of nickel allergy due to the handling of coins. In the present work, the transfer of metallic contamination during the manipulation of coins is examined by means of leaching experiments and manipulation tests. It is shown that pre-existing metallic species ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2003.00028.x
更新日期:2003-04-01 00:00:00
abstract::Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...
journal_title:Contact dermatitis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0536.2001.045003146.x
更新日期:2001-09-01 00:00:00
abstract::We patch tested 141 patients with 0.05% aq. thimerosal and 222 patients with 0.05% aq. mercuric chloride, including 63 children. The frequency of positive patch test reactions to thimerosal was 16.3%. There was a marked preponderance in the young age groups after vaccination, while none of 36 infants (aged 3-48 months...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1991.tb01694.x
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:Several studies have assessed the effect of patient education regarding hand eczema (HE) severity and quality of life. Few studies, however, have evaluated patients' knowledge. OBJECTIVES:To examine knowledge of skin protection in HE patients following a guided talk, and to identify variables associated wit...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13264
更新日期:2019-08-01 00:00:00
abstract::A 59-year-old saleswoman of black hats presented with a severe purpuric eruption of the exposed areas of the face, neck and arms. Patch testing to paraphenylenediamine produced a purpuric test reaction. Similar eruptions have been reported due to N-isopropyl-N-phenylparaphenylenediamine (IPPD), a rubber antioxidant. T...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1978.tb03793.x
更新日期:1978-08-01 00:00:00
abstract::Numerous studies have focused attention on the influence of various biological and environmental factors on contact hypersensitivity. In order to evaluate the persistence and/or modification of allergic contact sensitivity to a number of common contact sensitizers, the same standardized patch tests were repeated on 17...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02222.x
更新日期:1996-05-01 00:00:00
abstract::Sixteen patients with verified light sensitivity to both UVB and UVA wavebands showed allergic reactions to various lichen plants (Parmelia spp., Hypogymnia spp., Pseuodovernia spp., Cladonia spp., Platismatia spp., Physcia spp., Umbilicaria spp. and Cetraria spp.). Among the aromatic lichen compounds, atranorin was o...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1980.tb03911.x
更新日期:1980-01-01 00:00:00
abstract::Risk assessment serves to ensure that dermal exposure to skin sensitizers does not result in the acquisition of allergic skin disease. Traditionally, the approach adopted was one of comparative analysis, involving benchmarking against other allergens of known potency. More recently, efforts have been made to embrace a...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.2006.01082.x
更新日期:2007-06-01 00:00:00
abstract::This report reviews individual-related variables, environment-related variables and instrument-related variables, with a focus on the Evaporimeter EP1 (ServoMed). Start-up and use is described, and guidelines for good laboratory practice given. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1990.tb01553.x
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Thiurams and dithiocarbamates are structurally related sensitizing rubber accelerators. OBJECTIVES:To study patterns of simultaneous patch test reactions to thiurams and dithiocarbamates at the Finnish Institute of Occupational Health in 1991-2015. METHODS:We searched the patch test files for patients with...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12687
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Contact allergy to cocamidopropyl betaine has been attributed to its impurities dimethylaminopropylamine and cocamidopropyl dimethylamine. OBJECTIVES:To describe patients with positive patch test reactions to cocamidopropyl betaine-related compounds in an occupational dermatology clinic. METHODS:We reviewe...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2011.02036.x
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:The use of permanent hair dyes exposes hairdressers to contact allergens such as p-phenylenediamine (PPD), and the preventive measures are insufficient. OBJECTIVES:To perform an in vivo test to study the protective effect of gloves commonly used by hairdressers. PATIENTS/MATERIALS/METHODS:Six gloves from S...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12320
更新日期:2015-04-01 00:00:00
abstract::We studied 39 patients with erythema-dyschromicum-perstans-like dermatitis seen at Changuinola Hospital in Panama. They were compared with 41 controls. The 2 groups were native field workers of the banana plantations exposed to many pesticides. In 34 patients, there was a positive patch test reaction to 2,4,5,6-1,3-te...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02360.x
更新日期:1996-10-01 00:00:00
abstract::To investigate the mechanisms of non-immunologic contact urticaria (NICU), the effect of 120 mg of terfenadine (H1-antagonist) on contact reactions to methyl nicotinate, diethyl fumarate, benzoic acid, cinnamic acid, cinnamic aldehyde and dimethyl sulfoxide was studied in 20 subjects. Erythema and edema were observed ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1987.tb01429.x
更新日期:1987-04-01 00:00:00
abstract::Sensitization to olive oil is seldom reported in the literature. By use of epicutaneous tests a delayed type of hypersensitivity to pure freshly-prepared olive oil could be demonstrated in two patients. Patch tests with certain major constituents of olive oil; the methyl ester of linoleic acid, the glyceryl ester of p...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1981.tb04086.x
更新日期:1981-11-01 00:00:00
abstract::In four patients suffering from allergic contact eczema, the risk of sensitization to a new residue-leaving fungicide (Plondrel) used in spraying roses is considered. Two patients, however, were probably also sensitized to materials from the roses themselves. By gas-liquid chromatography the amount of the fungicide, e...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05441.x
更新日期:1975-10-01 00:00:00
abstract::The Persian cloth shoe (Maleki) which has been in use for more than 800 years has a strong cloth sole and a woven cotton upper. In the last 20 years, used car tires have become readily available in Iran and the soles of some shoes are now made from these. A man with the typical picture of rubber dermatitis on the sole...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1977.tb03605.x
更新日期:1977-04-01 00:00:00
abstract:BACKGROUND:Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states. OBJECTIVES:To characterize patients with chromium allergy and their di...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12291
更新日期:2014-12-01 00:00:00
abstract::The allergenicity and the cross-reactivity of naphthenic acid (NA) and its metallic salts were evaluated in experimental animals. In the guinea pig maximization test, sensitizing skin reactions were observed with cobalt naphthenate (CoN), zinc naphthenate (ZnN) and NA, but not with copper naphthenate, with CoN being t...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2006.00728.x
更新日期:2006-01-01 00:00:00
abstract::1310 patients were routinely patch tested with a paratertiary-butylphenol-formaldehyde resin (PTBP-F-R), a resol resin based on phenol and formaldehyde (P-F-R-2), and a mixture of these 2 resins. Approximately 2.5 times more patients with contact allergy to phenol-formaldehyde resins were diagnosed when routinely patc...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1988.tb05507.x
更新日期:1988-08-01 00:00:00
abstract::Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1983.tb04459.x
更新日期:1983-11-01 00:00:00
abstract::The case of a 40-year-old woman with severe edema of the face and neck after the injection of a local dental anesthetic is presented. The reaction is attributed to the presence of sodium metabisulfite, and antioxidant, in the local anesthetic. Both the anesthetic and the sodium metabisulfite gave a delayed positive pa...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03120.x
更新日期:1989-02-01 00:00:00
abstract::Investigations on light reactions in a patient with vitiligo are presented. The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1983.tb04429.x
更新日期:1983-09-01 00:00:00
abstract::A comparison was made between the guinea pig maximization test (GPMT), open epicutaneous test (OET) and chamber test (CT), and the allergens were neomycin sulphate and propylene glycol (PG). The sensitization rate for neomycin in petrolatum was 35% in GPMT, 25% in OET and 25% in CT. The corresponding figures for neomy...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1980.tb04960.x
更新日期:1980-08-01 00:00:00
abstract::9 common spices were tested epicutaneously in 338 dermatological patients, 118 of whom were allergic to balsam of Peru. Positive reactions to one or more spices were seen in 50 patients all of whom except 2 were allergic to balsam of Peru. The spices giving positive reactions most often were clove, Jamaica pepper and ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1984.tb00168.x
更新日期:1984-07-01 00:00:00
abstract::According to some reports in the literature, the hormonal fluctuations which occur during the menstrual cycle may affect the clinical expression of contact allergy to a greater or lesser degree. In clinical practice, too, patient history often shows exacerbation of the contact dermatitis during the days immediately pr...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2005.00588.x
更新日期:2005-06-01 00:00:00
abstract::A 24-year-old female working in the Department of Pathology of a University Hospital developed an acute peri-ocular eczema clearly being related to her daily work at the microscope. Patch testing revealed delayed type hypersensitivity against the black rubber mix, N-isopropyl-N'-phenyl paraphenylenediamine, N-cyclohex...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.0105-1873.2006.00876.x
更新日期:2006-08-01 00:00:00
abstract::Exposure to formaldehyde is common from both consumer products and industry. The reliability of the patch test is essential for the diagnosis of formaldehyde allergy as it is difficult to suspect from the patient's history. The recommended formaldehyde patch test concentration has been reduced over the last decades fr...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1998.tb05630.x
更新日期:1998-01-01 00:00:00
abstract::The development of hand eczema was evaluated in an 8-year follow-up study carried out in 51 junior hairdressers. Predisposing factors were investigated. Data were collected by use of a self-administered questionnaire: 74% response. None of the junior hairdressers presented with hand eczema at the start of the survey. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02193.x
更新日期:1996-04-01 00:00:00
abstract::Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1997.tb00393.x
更新日期:1997-03-01 00:00:00