Abstract:
:A comparison was made between the guinea pig maximization test (GPMT), open epicutaneous test (OET) and chamber test (CT), and the allergens were neomycin sulphate and propylene glycol (PG). The sensitization rate for neomycin in petrolatum was 35% in GPMT, 25% in OET and 25% in CT. The corresponding figures for neomycin in PG were 30% in GPMT, 45% in OET and 32% in CT. PG caused no hypersensitivity in 118 guinea pigs. The results suggested that as a hygroscopic, irritant and penetrating vehicle PG facilitates the induction of delayed contact allergy, especially in OET.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Kero M,Hannuksela Mdoi
10.1111/j.1600-0536.1980.tb04960.xsubject
Has Abstractpub_date
1980-08-01 00:00:00pages
341-4issue
5eissn
0105-1873issn
1600-0536journal_volume
6pub_type
杂志文章abstract:BACKGROUND:Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states. OBJECTIVES:To characterize patients with chromium allergy and their di...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12291
更新日期:2014-12-01 00:00:00
abstract::The occurrence and causes of occupational dermatoses at a film laboratory following modernization was studied. In 1983 the film laboratory moved to new premises built to reduce exposure to hazardous chemicals. The study was carried out during 1983-1986 with repeated interviews and dermatological examinations of all em...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb04656.x
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:The bark of the cinnamon tree is used as a spice; its flavour is from an essential oil containing mainly cinnamal. OBJECTIVE:To report new cases of occupational allergic contact dermatitis (ACD) from cinnamon and a novel case of airborne cinnamon contact allergy. METHODS:We examined the patient material of...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2008.01486.x
更新日期:2009-02-01 00:00:00
abstract::Three cases of contact allergy to Kathon CG, a preservative for cosmetics and toiletries containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one are presented. In two patients, Kathon CG was contained in a moisturizing cream, and the third was sensitized by a diagnos...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1985.tb01057.x
更新日期:1985-02-01 00:00:00
abstract::Murine models for the assessment of the contact sensitizing properties of chemicals rely on mouse ear swelling tests (Mest), which are not sensitive enough to detect weak sensitizers. The aim of the present study was to develop in mice an adjuvant-free Mest appropriate for in vivo detection of any type of sensitizer (...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1994.tb00650.x
更新日期:1994-04-01 00:00:00
abstract::Thirty-six of 37 veterinary surgeons with incapacitating dermatitis had allergic contact dermatitis, mainly from antibiotics such as spiramycin, Penethamate BP and tylosin. Eight were sensitive to rubber materials. Twenty of 36 had positive prick or scratch tests, mainly to animal hair. The atopic sensitivities were r...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1980.tb03885.x
更新日期:1980-01-01 00:00:00
abstract::The incidence of contact sensitivity to standard allergens present in the daily environment, such as chromium ion, cobalt, nickel and formaldehyde, is found to decrease in the fourth decade. It strongly suggests the presence of some immunoregulation in human beings, because sensitivity to these allergens should be equ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1979.tb04910.x
更新日期:1979-12-01 00:00:00
abstract::In this study, 333 nurses, 92 dentists and 167 doctors were investigated. Most positive patch tests obtained were unrelated to occupation. Nurses were most often sensitized to penicillins and, of the disinfectants, formaldehyde was the commonest cause of occupational dermatitis. Among dentists, the most common occupat...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03140.x
更新日期:1989-04-01 00:00:00
abstract::3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong s...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1990.tb03229.x
更新日期:1990-08-01 00:00:00
abstract::In recent years, there has been a dramatic rise in our understanding of contact dermatitis. This paper is a review of our knowledge of the mechanisms involved in contact dermatitis and related phenomena, the investigation of these events and the emergence of significant new allergens during the last 5 years. ...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.1987.tb01382.x
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:Panthenol (synonym: dexpanthenol), the alcohol analogue of panthothenic acid, is frequently included in moisturizers, wound-healing agents, and other cosmetics, and has been shown to be responsible for allergic contact dermatitis (ACD). OBJECTIVES:To evaluate the frequency of ACD caused by dexpanthenol, and...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13054
更新日期:2018-11-01 00:00:00
abstract::Protein kinase C (PKC) isoforms are important in cell signal transduction associated with regulation of cell proliferation and differentiation. In this study, alterations of PKC isoform levels in irritant patch test reactions were detected by Western immunoblots. 4 chemically and structurally different irritants, 4% a...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1998.tb05766.x
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:The presence of hexavalent chromium (Cr[VI]), which is carcinogenic to humans and a dermal sensitizer, in tattoo inks may represent a serious health concern. The level of this impurity is limited to 0.2 mg/kg in tattoo inks by the European Resolution ResAP(2008)1. OBJECTIVES:To analyse 29 tattoo inks, produ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13051
更新日期:2018-10-01 00:00:00
abstract::Acute irritant contact dermatitis (ICD) is frequently treated with cool water or saline compresses. While presumed effective, little quantitative evaluation documents the treatment's benefit. This study sought to determine the efficacy of both distilled water and physiologic saline compresses on experimentally-induced...
journal_title:Contact dermatitis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0536.2001.045003146.x
更新日期:2001-09-01 00:00:00
abstract::Nickel is used in coins because the metal has beneficial properties, including price, colour, weight, and corrosion resistance, and also because it is easy to stamp. It has often been claimed that the duration of skin contact with coins is too short to cause nickel release and dermatitis. However, it is well known by ...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.2012.02127.x
更新日期:2013-01-01 00:00:00
abstract::Exposure to formaldehyde is common from both consumer products and industry. The reliability of the patch test is essential for the diagnosis of formaldehyde allergy as it is difficult to suspect from the patient's history. The recommended formaldehyde patch test concentration has been reduced over the last decades fr...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1998.tb05630.x
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Preservatives such as formaldehyde and formaldehyde-releasers are common causes of contact allergy. OBJECTIVES:To examine trends in contact allergy to formaldehyde and formaldehyde-releasers in patch tested patients in Denmark over a 10-year period (2007-2016), and to investigate relevant sources of formald...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13052
更新日期:2018-11-01 00:00:00
abstract::Twelve standard textile dyes were analyzed using thin layer chromatography and studied comparatively with dyes supposed to be chemically similar, having the same Colour Index number or Registration Code. According to the chromatograms, Disperse Yellow 3, Disperse Orange 1, Disperse Orange 3 and Disperse Orange 13 seem...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1986.tb05281.x
更新日期:1986-05-01 00:00:00
abstract::Erythema caused by occlusion of 3 concentrations of surfactant was quantified in vivo using a modified spectrophotometer. Standard chamber irritation test sites were evaluated objectively using the spectrophotometer and subjectively by trained observers. There was a good relationship between the instrumental and visua...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1988.tb02893.x
更新日期:1988-09-01 00:00:00
abstract:BACKGROUND:The preservative methyldibromo glutaronitrile (MDBGN) has been banned, first from stay-on, and later from rinse-off cosmetics, in the EU countries because of increasing rates of contact allergy. OBJECTIVES:To evaluate the frequency of contact allergy to MDBGN among patients patch tested by the Danish Contac...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2008.01364.x
更新日期:2008-07-01 00:00:00
abstract::An outbreak of occupational dermatitis in a rubber tyre factory is reported. An unusual clinical picture was recognized. Patch tests revealed a high sensitization rate to the MBT derivative used: 2-(2'-4'dinitrophenylthio)benzothiazole. Since tests with MBT mix and dinitrophenol were negative; sensitization to a conta...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1987.tb02637.x
更新日期:1987-07-01 00:00:00
abstract::The introduction of the euro has revived interest in the risk of nickel allergy due to the handling of coins. In the present work, the transfer of metallic contamination during the manipulation of coins is examined by means of leaching experiments and manipulation tests. It is shown that pre-existing metallic species ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2003.00028.x
更新日期:2003-04-01 00:00:00
abstract::"Eau de Javel" (liquid bleach) is a common cause of chromate contact allergy. A historical review explains the reasons for the addition of sodium dichromate after the First World War. The chromium content in different brands of eau de Javel has been determined by flameless atomic absorption spectrophotometry. The resu...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1980.tb03916.x
更新日期:1980-01-01 00:00:00
abstract::In 1988, 64% of our patients patch test positive to at least 1 allergen of the ICDRG standard series were nickel sensitive. In 70% of 300 patients evaluated, dermatitis started on the earlobes and was related to the regular wearing of cheap earrings. At the same time, 62% of 735 young schoolgirls were found to have de...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb03203.x
更新日期:1989-10-01 00:00:00
abstract:BACKGROUND:Hyperkeratotic hand eczema (HHE) is a typical clinical hand eczema subtype with a largely unknown pathophysiology. OBJECTIVE:To investigate histopathology, expression of keratins (K), epidermal barrier proteins, and adhesion molecules in HHE. METHODS:Palmar skin biopsies (lesional and perilesional) were ob...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13572
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Polyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad-spectrum antimicrobial substance used as a preservative in many products. Due to our limited knowledge on PHMB contact allergy frequency and the fact that cases of allergic contact dermatiti...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.13728
更新日期:2020-10-24 00:00:00
abstract::The Nyloprint process is becoming more frequently used in Great Britain. We report a case of contact dermatitis in a 60-year-old man who was employed in the production of Nyloprint formes. The process is described in detail. Patch tests showed him to be very sensitive to an acrylamide derivative, which is used as a mo...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1976.tb03013.x
更新日期:1976-06-01 00:00:00
abstract::Rubber chemicals are among the most common occupational contact sensitizers. The most common rubber sensitizers are thiurams, thiazoles, carbamates and paraphenylenediamine derivatives. Here we present data on a less-well-known rubber chemical, N-(cyclohexylthio)phthalimide (CTP; CAS 17796-82-6). This chemical is curr...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02106.x
更新日期:1996-01-01 00:00:00
abstract::We showed earlier that most patients with contact dermatitis due to corticosteroids show cross-reactions when patch tested with hydrocortisone-17-butyrate (H-17-B). To test whether H-17-B could be used for detecting topical corticosteroid allergy, we screened patients undergoing routine patch testing with H-17-B. Pati...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1989.tb04729.x
更新日期:1989-09-01 00:00:00
abstract::The purpose of the present study was to compare the frequency of lanolin allergy during two periods and to assess the adequacy of testing with one standard allergen. Among 1230 consecutive patients with eczema who were standard patch tested, 33 (2.7%), 21 females and 12 males, gave a positive reaction to wool alcohols...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1979.tb04824.x
更新日期:1979-05-01 00:00:00