Chlorothalonil, a possible cause of erythema dyschromicum perstans (ashy dermatitis).

Abstract:

:We studied 39 patients with erythema-dyschromicum-perstans-like dermatitis seen at Changuinola Hospital in Panama. They were compared with 41 controls. The 2 groups were native field workers of the banana plantations exposed to many pesticides. In 34 patients, there was a positive patch test reaction to 2,4,5,6-1,3-tetrachloroisophthalonilnitrile (chlorothalonil, TCPN) 0.001% in acetone. In 39 cases, biopsies showed a lichenoid tissue reaction compatible with a chronic pigmented dermatitis or erythema-dyschromicum-perstans-like dermatitis. Chlorothalonil is possibly the cause of the pigmented dermatitis observed in the 39 banana farm workers studied. Until additional studies are carried out, we consider this a possible rather than definite cause-and-effect relationship.

journal_name

Contact Dermatitis

journal_title

Contact dermatitis

authors

Penagos H,Jimenez V,Fallas V,O'Malley M,Maibach HI

doi

10.1111/j.1600-0536.1996.tb02360.x

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

214-8

issue

4

eissn

0105-1873

issn

1600-0536

journal_volume

35

pub_type

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